Clinical trials: Abdominal Distension
Gastroparesis
Cardiac Vagal Effects of GES in Patients With Gastroparesis and Vagal Nerve Action Potentials in Vagus Nerve
The objective of this study is to determine if Gastric Electrical Stimulation may influence vagal outflow via vagal afferent fibers that terminate in the Central Nervous System.
- Trial name
- GES (NCT02159586)
- Testing
- gastric electrical stimulator
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Indiana University
Gastrointestinal Discomfort, Gastrointestinal Side Effects of GLP-1 Receptor Agonist Use
A Study to Evaluate the Effects of a Supplement on Gut Comfort in GLP-1 Receptor Agonist Users
This is a randomized, triple-blind, placebo-controlled, virtual clinical trial evaluating the effects of the Oxxynea® botanical supplement on gut comfort in adults who use GLP-1 receptor agonists (GLP-1 RAs).
- Conditions
- Gastrointestinal Discomfort, Gastrointestinal Side Effects of GLP-1 Receptor Agonist Use, Nausea, Abdominal Pain
- Trial name
- NCT07898189
- Testing
- Oxxynea® Supplement
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- AB Mauri (UK) Limited,
Gastrointestinal Irritation, Nutrition, Healthy
Effects of Wheat Flour Milling Method on Glycemic Response and Gastrointestinal Symptoms
The goal of this clinical trial is to learn if the way wheat flour is ground - by stone milling (an older method) or roller milling (used for most flour today) - changes blood sugar levels after eating bread, in healthy adults…
- Trial name
- STONEMILL (NCT07858110)
- Testing
- Stone-milled wheat flour bread, Roller-milled wheat flour bread (sourdough)
- Where
- Norway
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Constipation, Bloating
Impact of the Inno Cleanse Dietary Supplement on Gut Health and Associated Variables in Healthy Men and Women
The purpose of the present study is to investigate the impact of a natural dietary supplement, Inno Cleanse™, to reduce bloating in a population of otherwise healthy men and women, who claim to feel frequently bloated.
- Trial name
- NCT07215351
- Testing
- Dietary supplement for digestive health
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Neuromuscular Blockade
Influence of Analgesia and Neuromuscular Block on Abdominal Distension and Operating Conditions Laparoscopic Operations
Neuromuscular block improves operation conditions during laparoscopic surgery. In this study, a new measurement tool is assessed: the degree of abdominal distension during the time course of the neuromuscular block is measured…
- Trial name
- NCT03605628
- Testing
- measuring tape, neuromuscular block, Surgical rating score
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Kreiskrankenhaus Dormagen
Abdominal Pain
The Effect of Progressive Muscle Relaxation on Abdominal Pain and Distension in Colonoscopy Patients.
Patients undergoing colonoscopy were divided into progressive relaxation exercises and control groups. Pretest and posttest abdominal pain and distention scores of the patients were determined after colonoscopy.
- Trial name
- NCT04935645
- Testing
- Progressive Muscle Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Mardin Artuklu University
Constipation, Bloating
A Study of Microbiome Transplantation for the Treatment of Constipation and/or Significant Bloating in Patients With Systemic Sclerosis
The purpose of this study is to characterize the intestinal flora in subjects with systemic sclerosis-related constipation and/or significant bloating and to determine safety and trends in improvements in the diversity of colonic…
- Trial name
- NCT06827977
- Testing
- PRIM-DJ2727
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The University of Texas Health Science Center, Houston
Colonoscopy Pain, Abdominal Distension
Effect of Foot Bath After Colonoscopy
This randomized controlled trial evaluated whether a 30-minute foot bath with warm water (40-41°C) after colonoscopy reduces post-procedure pain and abdominal distension and shortens the time to first passage of flatus.
- Trial name
- FOOTBATH-COL (NCT07636109)
- Testing
- Warm foot bath
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kocaeli University
Indigestion, Nausea
YM443 in Subjects With Functional Dyspepsia
The primary objective of this study will be to characterize the dose response profile of YM443 in subjects with functional dyspepsia (FD) to enable the selection of doses for the Phase 3 clinical trial.
- Trial name
- NCT00102310
- Testing
- YM443
- Where
- 59 sites in United States
- Volunteers
- 416 people
- Sponsor
- Astellas Pharma Inc
Constipation - Functional, Abdominal Pain (AP)
Co-Development and Validation of Colonic Symptom Pictograms for Young People
Severe constipation affects 10% of children, often leading to significant physical and emotional distress. While constipation is commonly associated with impaired bowel movements, it is fundamentally linked to abnormalities in…
- Conditions
- Constipation - Functional, Abdominal Pain (AP), Nausea and Vomitting, Bloating
- Trial name
- NCT07337343
- Testing
- Pictogram comprehension and validation
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Bloating, Distension
Investigation of the Relationship Between Core Muscles Functions and Symptoms of Patients with Abdominal Bloating/Distension
The aim of this study is to investigate the relationship between core muscle functions (strength, endurance, thickness) and symptoms in individuals with abdominal bloating/distension.
- Trial name
- NCT06659874
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Dokuz Eylul University
Aortic Aneurysm, Abdominal, Popliteal Artery Aneurysm
Venous Distension in Patients With Aneurysmatic Arterial Disease
The aim of the study is to assess if venous distension in patients with aneurysmatic arteriopathy is higher compared to patients with peripheral arterial occlusive disease (PAOD) and in controls.
- Conditions
- Aortic Aneurysm, Abdominal, Popliteal Artery Aneurysm, Peripheral Arterial Occlusive Disease, Vascular Diseases
- Trial name
- NCT02867501
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Baselland Bruderholz
Healthy
Efficacy of Dietary Supplement in Subjects With Acid Reflux and/or Abdominal Bloating/Distention and GI Symptoms
This study was a prospective randomized clinical study. There was interventional treatment for a total of 8 weeks including a 2-week washout period.
- Trial name
- NCT06808867
- Testing
- Dietary Supplement with Active Ingredient Blend
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Olly, PBC
Premenstrual Dysphoric Disorder
Intranasal PH80 Spray for Acute Management of the Symptoms of Premenstrual Dysphoric Disorder
The objective of this study is to evaluate the effectiveness and safety in double-blind, randomized, placebo-controlled clinical trials of self administered PH80 intranasal spray for the acute management of cycle related symptoms…
- Trial name
- PH80-PMD (NCT01217775)
- Testing
- PH80
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- Pherin Pharmaceuticals, Inc.
Gut Health, Bowel Movements
A Clinical Trial to Evaluate the Effect of ConcenTrace Trace Mineral Drops on Gut Health
This is a virtual single-arm trial that will last 12 weeks. Participants will take the drops daily and complete questionnaires at Baseline, Week 4, Week 8, and Week 12.
- Conditions
- Gut Health, Bowel Movements, Constipation, Bloating
- Trial name
- NCT06122571
- Testing
- ConcenTrace
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trace Minerals
Postprandial Abdominal Distension, Bloating
A Study to Evaluate Acute and Short-term Efficacy of Digest Gold on Postprandial Abdominal Distension and Subjective Bloating in Healthy Adults
The goal of this clinical trial is to investigate the acute and short-term efficacy of Digest Gold on postprandial abdominal distension and subjective bloating in healthy adults.
- Trial name
- NCT07830992
- Testing
- Digest Gold
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Enzymedica
Stomach Distended, Bloating
Examining the Effectiveness of Digestive Enzymes at Reducing Bloating and Stomach Distension
Flatter Me is a product that includes digestive enzymes in a way to support digestion of macronutrients and their constituents and provides herbs traditionally used for digestive health support.
- Trial name
- NCT05520411
- Testing
- HUM Flatter Me
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- HUM Nutrition, Inc.
Stool Assessment, Skin Rash
GI Symptoms in Infants Fed Goat Milk-based Infant Formula
A cross-sectional observational survey was conducted in Brazil, Mexico, Russia, and The Netherlands by recruiting parents/legal guardians through social media.
- Conditions
- Stool Assessment, Skin Rash, Urticaria, Regurgitation
- Trial name
- NCT06755424
- Where
- Netherlands
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Cystic Fibrosis, Abdominal Pain
Rifaximin for Treatment of Bloating in Children and Adults With Cystic Fibrosis
Gastrointestinal symptoms are commonly reported in as much as 65% of people with CF even independent of pancreatic enzyme replacement therapy (PERT) and the most frequent of these symptoms are bloating/distension, flatulence…
- Conditions
- Cystic Fibrosis, Abdominal Pain, Small Bowel Disease
- Trial name
- NCT05408910
- Testing
- Rifaximin 550 MG Oral Tablet [XIFAXAN]
- Sponsor
- Wake Forest University Health Sciences
Dyspepsia
Effect of Itopride, on Symptoms of Functional Dyspepsia, Such as Indigestion, Bloating, Inability to Finish a Meal
Itopride is a new compound that is already marketed in Japan and in some countries of Eastern Europe under the name of Ganaton. It is used to treat symptoms of functional dyspepsia.
- Trial name
- NCT00112177
- Testing
- Itopride Hydrochloride
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Forest Laboratories