Clinical trials: Abdominal Distension
Asymptomatic Conditions
Assessing the Effect of Lettuce on Intestinal Water Content Through Magnetic Resonance Imaging of the Small Bowel
When patients have bowel surgery they are sometimes left with a stoma, where the small bowel exits onto the wall of the abdomen, not into the colon.
- Trial name
- LETIS (NCT02939716)
- Testing
- Rhubarb, Bread, Lettuce
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Idiopathic Gastroparesis
A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adult Subjects With Idiopathic Gastroparesis.
The goal of this clinical trial is to evaluate if the study drug CIN-102 (deudomperidone) can help to decrease nausea severity associated with idiopathic gastroparesis severity in adult subjects.
- Trial name
- NCT06899217
- Testing
- CIN-102 Dose 15mg, CIN-102 Dose 10mg
- Where
- 85 sites in United States
- Volunteers
- 416 people
- Sponsor
- CinDome Pharma, Inc.
Constipation - Functional, Abdominal Distension
Stress Ball and Video Distraction During Pediatric Enema
This randomized controlled trial aims to evaluate the effects of stress ball use and video distraction during enema administration on fear, anxiety, and pain levels in children treated in the pediatric emergency department.
- Trial name
- SAVE (NCT07695428)
- Testing
- Stress Ball, Video Distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Manisa Celal Bayar University
Gastrointestinal Symptoms, Bloating
A Clinical Trial to Evaluate the Effects of Super Liver Liquid Drops on Gut Health, Digestive Comfort, and Daily Energy Levels
This is a decentralized (fully virtual), single-group, open-label, prospective clinical trial evaluating the effects of Super Liver Liquid Drops, a liquid botanical dietary supplement, on gut health, digestive comfort, energy…
- Conditions
- Gastrointestinal Symptoms, Bloating, Digestive Discomfort, Low Energy Levels
- Trial name
- NCT07742657
- Testing
- Super Liver
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- SuperBonsai Inc.
Small Intestinal Bacterial Overgrowth, SIBO
The Safety And Efficacy Of A Probiotic Intervention On Lactulose Hydrogen Breath Test-Positive Patients And Related Gastrointestinal Symptoms
The goal of this study is to test the effect of a probiotic formulation on gastrointestinal symptoms, gut and small intestine microbiota in participants suffering from small intestinal bacterial overgrowth (SIBO).
- Trial name
- NCT06317441
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Nimble Science Ltd.
Chronic Diarrhea, Abdominal Pain
Antiparasitic Treatment for Returning Travelers With Chronic Diarrhea
Study hypotheses is that Antiparasitic therapy in patients with chronic diarrhea after travel to a developing country, with a negative stool findings, will be significantly effective in eliminating diarrhea and other…
- Conditions
- Chronic Diarrhea, Abdominal Pain, Bloating
- Trial name
- NCT01070277
- Testing
- Tinidazole and Albendazole
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Feeding Intolerance, Abdominal Distention
SAFEstart Feeding Intolerance Study Phase II
Feeding intolerance is a common problem in the NICU. Feeding intolerance complicates the hospitalization, lengthens the hospital stay, and adds substantially to the cost of care.
- Conditions
- Feeding Intolerance, Abdominal Distention, Gastric Residual, Emesis and Diarrhea
- Trial name
- NCT00331201
- Testing
- SAFEstart
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Intermountain Health Care, Inc.
Healthy
The Effect of Post Colonoscopy Abdominal Massage on Abdominal Pain, Distension, Discomfort and Patient Satisfaction
Background: Abdominal pain, distension, and discomfort are the most frequently seen side effects after colonoscopy. These side effects can cause physical and mental results and increased workloads and care costs.
- Trial name
- NCT04979351
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
IBS - Irritable Bowel Syndrome, Healthy
Capsule Microbiota Sampling in IBS/Functional Gastrointestinal Disease
We will sample intestinal microbiota using a microbiome sampling capsule in Healthy, Irritable Bowel Syndrome (IBS), and Functional Gastrointestinal Disease.
- Conditions
- IBS - Irritable Bowel Syndrome, Healthy, Functional Bloating, Functional Gastrointestinal Disorders
- Trial name
- NCT06215222
- Testing
- Microbiota Sampling
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
Irritable Bowel Syndrome
Safety Study of Probiotics in Adults With Irritable Bowel Syndrome
Determine the safety and preliminary effectiveness of VSL#3 in adults with IBS.
- Trial name
- NCT00971711
- Testing
- Probiotic
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Baylor College of Medicine
Functional Dyspepsia
Trial of Itopride 150mg Once a Day Versus Itopride 50 mg Thrice a Day; in Patients With Functional Dyspepsia
The study is conducted in patients with functional dyspepsia or chronic gastritis. The purpose of this study is to: assess whether the dose of Itopride Hydrochloride 150 mg extended release tablets, taken once daily has a similar…
- Trial name
- NCT06217393
- Testing
- Itopride Hydrochloride 150 mg extended release tablets, Itopride Hydrochloride 50 mg film coated tablets
- Where
- 19 sites in Armenia, Malaysia and 3 more
- Volunteers
- 564 people
- Sponsor
- Abbott
Dyspepsia
The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia.
"Functional dyspepsia" has been defined loosely as "pain or discomfort centered in the upper abdomen." The symptoms can also include fullness, early satiety, bloating, belching, nausea, retching and vomiting.
- Trial name
- NCT00303264
- Testing
- dexloxiglumide, Nexium (esomeprazole)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Forest Laboratories
Irritable Bowel Syndrome, Abdominal Bloating
Galactol® Enzyme Supplement for Post-Prandial Abdominal Bloating in Irritable Bowel Syndrome
This multicenter, randomized, controlled clinical trial aims to evaluate the efficacy and safety of a dietary supplement containing a combination of digestive enzymes (alpha-galactosidase, beta-galactosidase, and…
- Trial name
- NCT07465562
- Testing
- Galactol®, High-FODMAP Exclusion Diet
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Colorectal Cancer
RADOX' Reduced Abdominal Distension and Oxygen Delivery
The use of laparoscopic surgery is continuing to increase in colorectal resection and expected reach 80% in the next 10 years. Although laparoscopic (keyhole) or minimally invasive surgery can lead to faster recovery it can also…
- Trial name
- RADOX (NCT02045680)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Dr Michael Scott
Abdominal Distention, Abdominal Bloating
Clinical Characteristics of Small Intestinal Bacterial Overgrowth in Individuals With Abdominal Bloating/Distention
Abdominal bloating/distention represents a prevalent clinical manifestation characterized by an unclear etiology and pathogenesis.
- Trial name
- NCT06285734
- Testing
- Breath test
- Where
- China
- Volunteers
- 387 people
- Sponsor
- Shandong University
Functional Bowel Disorder
Efficacy and Safety of Mebeverine + Simethicone in Patients With Functional Bowel Disorders
The parallel three-group study of efficacy and safety was planned to investigate the reduction in abdominal pain and bloating during treatment with the fixed-dose combination of Mebeverine + Simethicone versus Duspatalin® and…
- Trial name
- NCT05175131
- Testing
- Mebeverine+Simethicone, Mebeverine, Simethicone
- Where
- Russia
- Volunteers
- 465 people
- Sponsor
- Abbott