Clinical trials: Abdominal Fat
Abdominal Fat
A Study of MI226 Injection for Abdominal Fat Accumulation
This is a Phase 1, randomized, double-blind (with open-label sentinel cohorts), placebo-controlled, single-ascending-dose study designed to evaluate the safety, tolerability, and pharmacokinetics (PK) of MI226 Injection in…
- Trial name
- NCT07749742
- Testing
- MI226 injection（dose 1）, MI226 Injection（dose 2）, MI226 Injection（dose 3）
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Nanjing Minova Pharmaceutical Co., Ltd.
Fat Reduction in the Abdomen
Non-Invasive Reduction of Abdominal Fat Utilizing the CoolFlex and eZ App 6.3 Applicators
This study is being performed to reduce unwanted abdominal fat using two different applicators for the Zeltiq System.
- Trial name
- NCT01377740
- Testing
- The Zeltiq System
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Obesity, Visceral Obesity
Nutrition and Energy Restriction for Cancer Prevention
This study evaluates the effect of intermittent calorie restriction versus continued calorie restriction on weight loss, gene expression profile of subcutaneous adipose tissue and abdominal fat distribution.
- Conditions
- Obesity, Visceral Obesity, Weight Loss, Metabolic Diseases
- Trial name
- HELENA (NCT02449148)
- Testing
- Calorie Restriction
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- German Cancer Research Center
Abdominal Obesity
Physical Activity in Youth: Implications for Reversing Risk Factors for Type 2 Diabetes
In this randomized controlled trial, we will examine the effect of a 3-month exercise training (aerobic exercise versus resistance exercise) without calorie restriction on total and regional adiposity, and risk of type 2 diabetes…
- Trial name
- NCT00739180
- Testing
- Control, Resistance Exercise, Aerobic exercise
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Fat Burn
Non-invasive Lipolysis and Improvement of Muscle Tone in Lateral Abdomen
This study will evaluate the clinical efficacy and performance of the BTL-899 device for changes in subcutaneous fat and muscle tissue in the lateral abdomen region (also referred to as flanks or "love handles").
- Trial name
- NCT05540080
- Testing
- BTL-899
- Where
- 6 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Epicardial Fat Tissue (EFT), Chronic Non-Communicable Diseases (NCDs)
Epicardial Fat Tissue and Cardiometabolic Risk in Russian and Asian Populations
Visceral obesity is a well-established risk factor for the development of chronic non-communicable diseases (NCDs). Epicardial fat tissue (EFT) is located on the surface of the myocardium and may directly affect cardiac function…
- Conditions
- Epicardial Fat Tissue (EFT), Chronic Non-Communicable Diseases (NCDs), Visceral Obesity
- Trial name
- EPIGRAPH (NCT07604610)
- Where
- Russia
- Volunteers
- 500 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Obesity, Impaired Glucose Tolerance
Effects of Rosiglitazone on the Metabolic Phenotype of Impaired Glucose Tolerance in Youth
The purpose of the study is to determine whether treatment of children and adolescents with Impaired Glucose Tolerance (IGT) with rosiglitazone will lead to improvements in insulin sensitivity and glucose tolerance.
- Conditions
- Obesity, Impaired Glucose Tolerance, Type 2 Diabetes Mellitus
- Trial name
- NCT00413335
- Testing
- Rosiglitazone
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Yale University
Abdominal Subcutaneous Fat
Low-Frequency, High-Intensity Ultrasound for Waist Circumference Reduction
This study evaluates the effectiveness and safety of externally applied lower frequency ultrasound to the waist/abdominal region of adults to achieve a reduction of fat cells/tissues below the skin, evidenced by a reduction in…
- Trial name
- NCT04206384
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- CAO Group, Inc.
Abdominal Fat, Body Weight
Effects of Whole Grain on Weight Maintenance
Epidemiological studies suggest that whole grain consumption affects measures of obesity including BMI, body fat tissue, and body weight.
- Trial name
- NCT01239147
- Testing
- Diet rich in whole grain, Refined grain
- Where
- France
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Cereal Partners Worldwide
Excess Abdominal Fat
Clinical Study to Evaluate the Safety and Efficacy of the UltraShape Device for Non-Invasive Abdominal Fat Reduction
Prospective, blinded, one arm, baseline-controlled clinical study for the evaluation of the UltraShape treatment for non-invasive abdominal fat reduction. Study subjects will undergo UltraShape treatments on the abdominal area
- Trial name
- NCT02700152
- Testing
- UltraShape
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Subcutaneous Fat Disorder
Combination of Light and Ultrasound to Reduce Abdominal Fat
Light and ultrasound can be interesting alternatives to reduce abdominal fat. Thus, the main objective of this study will be to evaluate the effects of these isolated techniques and their association in subcutaneous abdominal…
- Trial name
- NCT05155683
- Testing
- Photobiomodulation (PBM) with infrared LED, Low-frequency ultrasound (LOFU), Muscle electrostimulation
- Where
- Brazil
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Visceral Obesity, Tooth Erosion
The Effect of Vinegar Consumption on Visceral Fat and Blood Glucose Concentration
The purpose of this study is to test the potential ability of vinegar to significantly decrease visceral fat in healthy adults with "central obesity".
- Conditions
- Visceral Obesity, Tooth Erosion, Insulin Resistance
- Trial name
- VIVO (NCT03577834)
- Testing
- liquid vinegar, vinegar pill
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Carol Johnston
Abdominal Obesity Metabolic Syndrome
Effects of Green-MED Diet Via the Gut-fat-brain Axis
Mediterranean (MED) diet, richer in plants/seeds (and dietary polyphenols) and low in processed meat (green-MED diet) may have a pronounced beneficial effect on age-related declines that begin in middle age, reflected by changes…
- Trial name
- DIRECT-PLUS (NCT03020186)
- Testing
- Physical activity, Physical activity+ MED diet, Physical activity+green MED diet
- Where
- Israel
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Ben-Gurion University of the Negev
Psoriasis, Arthritic Psoriasis
Evaluation of Adipokines and Fat Tissue in Psoriasis and Psoriatic Arthritis
Body composition analysis and especially body fat distribution in regions of interest (android and in particular intra-abdominal region) provides some information on the risk of cardiovascular disease.
- Trial name
- ADIPSO (NCT02849795)
- Testing
- bone densitometry, questionnaires, biological analyses
- Where
- France
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Abdominal Obesity, Physical Activity
Physical Activity in Overweight Girls: Implications for Reversing Risk Factors for Type 2 Diabetes
In this randomized controlled trial, we will examine the effect of a 3-month exercise training (aerobic exercise versus resistance exercise) without calorie restriction on total and regional adiposity, ectopic fat in the liver…
- Trial name
- NCT01323088
- Testing
- Control, Resistance Exercise, Aerobic exercise
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-Alcoholic Steato-Hepatitis (NASH)
How Abnormal Function of Fat Tissue in Type 1 Diabetes Contributes to Fat in the Liver
Steatotic liver disease associated with metabolic dysfunction (MASLD) is a disease caused by excess fat storage in the liver. Excessive fat delivery to the liver and MASLD typically occurs in people with abdominal obesity and…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-Alcoholic Steato-Hepatitis (NASH), Type 1 Diabetes Mellitus
- Trial name
- AGL14 (NCT07133854)
- Testing
- Imaging PET/MRI, Stable isotope infusions, meal test
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Obesity, Visceral, Obesity; Endocrine
Study of Lipolysis of Visceral Reserve Fat Using Tecar Therapy.
The Scope of this study is to assess the visceral and subcutaneous fat loss in patients having Tecar (Radiofrequency) Therapy and its effects on other anthropometric variables, adipokines and inflammation.
- Trial name
- NCT06377358
- Testing
- Tecar Therapy
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- CAPENERGY MEDICAL, SL
Diabetes Mellitus, Type 2, Insulin Resistance
Evaluation of Intra-Abdominal Fat Extraction Using HydraSolve T2D™ in Obese Subjects With Type 2 Diabetes
This study will investigate the safety and efficacy of the investigational use of the HydraSolve T2D™ System in improving blood glucose control and insulin resistance in patients with obesity (Class 1, BMI 30-39.9 kg/m2) and type…
- Trial name
- NCT03953963
- Testing
- HydraSolve T2D™
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medality Medical
Obese
Metabolism Associated With Abdominal Fat Mass Distribution
Objectives: The primary objective of this clinical trial is to characterize metabolic signatures associated with abdominal fat distribution in 40 women with different BMI 29-40 and different abdominal distribution of fat…
- Trial name
- NCT01726647
- Where
- 2 sites in Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Metabolic Syndrome
Effect of Physical Activity and Diet on the Treatment of Metabolic Syndrome
Metabolic syndrome has been defined as a group of associated risk factors for cardio-vascular diseases and diabetes. It is usually treated with an association of restrictive diet, physical exercise and drugs.
- Trial name
- NCT00917917
- Testing
- Type of physical activity (resistance, endurance), Restrictive diet
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand