Clinical trials: Abdominal Hernia
Drainage, Seroma
Effect of Drainage on the Incidence of Seroma After Laparoscopic Trans Abdominal Preperitoneal Inguinal Hernia Repair
The aim of the study is to evaluate the effect of drainage on the incidence of seroma after laparoscopic transabdominal preperitoneal inguinal hernia repair.
- Conditions
- Drainage, Seroma, Laparoscopic, Trans-abdominal
- Trial name
- NCT07681700
- Testing
- Trans-abdominal preperitoneal repair + Drainage, Trans-abdominal preperitoneal repair
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Obese Adults, Hernia Abdominal Wall
Tirzepatide-Based Prehabilitation Before Elective Ventral and Incisional Hernia Repair in Patients With Obesity
This study evaluated whether a 16-week weight-loss program using tirzepatide before elective ventral and incisional hernia surgery could improve surgical readiness and outcomes in patients with obesity.
- Conditions
- Obese Adults, Hernia Abdominal Wall, Prehabilitation
- Trial name
- NCT07638592
- Testing
- Tirzepatide prehabilitation
- Where
- Italy
- Volunteers
- 91 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Eventration, Regional Anesthesia
Serratus Intercostal Block Versus Epidural/Port Infiltration Analgesia in Eventration: Prospective Non Inferiority Study
Adequate pain control, rehabilitation and early postoperative recovery are currently the model to follow according to the recommended guidelines.In this project the main objective is to evaluate 2 different analgesic strategies…
- Conditions
- Eventration, Regional Anesthesia, Epidural; Anesthesia, Abdominal Hernia
- Trial name
- Analgesic Stra (NCT06014749)
- Testing
- undergo, ultrasound, Local anesthetic
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Hospital del Rio Hortega
Ventral Hernia, Hernia
Pilot Trial of Abdominal Core Rehabilitation To Improve Outcomes After Ventral Hernia Repair
This study aims to evaluate the potential role of physical therapy in improving outcomes after ventral hernia repair.
- Conditions
- Ventral Hernia, Hernia, Herniorrhaphy, Abdominal Wall
- Trial name
- ABVENTURE-P (NCT05142618)
- Testing
- Supervised Physical Therapy, Post-operative Precautions
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Ohio State University
Abdominal Hernia
Open Versus Robotic-assisted Ventral Hernia Repair, Short and Long-term Outcome
In this randomized clinical trial, the investigators will compare the conventional open repair for hernia in the anterior abdominal wall with the robotic-assisted approach.
- Trial name
- NCT05906017
- Testing
- Open Hernia surgery, Robotic Hernia surgery
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- University of Southern Denmark
Intra-Abdominal Hypertension, Inguinal Hernia
Measuring Intraabdominal Pressure, Lactic Acid, and Urine Output
This study serves as a pilot study with the intention to to measure intraabdominal pressure, lactic acid, and urine output in obese individuals undergoing laparoscopic inguinal hernia repair.
- Trial name
- NCT05070572
- Testing
- Accuryn Monitoring System
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Antonios Likourezos
Hernia, Ventral Hernia
Prospective Clinical Evaluation of High-Purity Type I Collagen in Select High-Risk Hernia Repair Scenarios
This prospective, single-arm clinical study evaluates the safety, feasibility, and early clinical outcomes of High-Purity Type I Collagen (HPTC; Surgicoll-Mesh®) when used as a biologic reinforcement in selected hernia repair…
- Conditions
- Hernia, Ventral Hernia, Incisional Hernia, İnguinal Hernia
- Trial name
- NCT07360691
- Testing
- High-Purity Type I Collagen Mesh
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Cholecystectomy, Hernia, Abdominal
Exploring the Impact of Genetic Variations on The Clinical Efficacy of Nalbuphine in Postoperative Pain Management
The goal of this study is to identify the genes as well as their association with Nalbuphine. This will help the investigator to identify opioid vulnerability in Pakistani population in the postoperative patients and will…
- Conditions
- Cholecystectomy, Hernia, Abdominal, Appendectomy, Open Colorectal Surgery
- Trial name
- Nal (NCT06996561)
- Testing
- Nalbuphine Injection, Next Generation Sequencing, whole exome sequencing
- Where
- Pakistan
- Volunteers
- 263 people
- Sponsor
- Dr. Asma Abdus Salam
Abdominal Wall Hernia
Preoperative Weight Loss for Open Abdominal Wall Reconstruction
The goal of this randomized controlled trial is to compare preoperative intensive weight management to upfront surgery in obese patients undergoing complex abdominal wall reconstruction.
- Trial name
- NCT05925959
- Testing
- Preoperative Weight Management Program
- Where
- 2 sites in United States
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Benjamin T. Miller
Abdominal Wall Hernia, Umbilical Hernia Repair
Evaluating the Efficacy of Suture Mesh vs. Planar Mesh in Ventral Hernia Treatment
The goal of this clinical trial is to investigate whether mesh-suture affects wound complication rates, patient-reported quality of life, and operation time in adult patients undergoing surgery for small ventral hernias.
- Conditions
- Abdominal Wall Hernia, Umbilical Hernia Repair, Epigastric Hernia Repair
- Trial name
- MeMa (NCT07476560)
- Testing
- mesh suture, planar mesh
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- Regionshospital Nordjylland
Hernia, Ventral Hernia Repair
Complication Rate of Onlay vs Sublay Mesh Repair in Incisional Hernia
This randomized controlled trial was conducted at the Department of Surgery, Hayatabad Medical Complex, Peshawar. Eligible patients with incisional hernia were randomized into two parallel groups: sublay mesh repair and onlay…
- Conditions
- Hernia, Ventral Hernia Repair, Incisional Hernia Repair, Abdominal Wall Hernia
- Trial name
- NCT07401446
- Testing
- Sublay Mesh Repair, Onlay Mesh Repair
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Abdominal Wall Hernia
Hernia Repair Using Rectus Fascia Allograft
Abdominal wall closure in highly complex patients is one of the most difficult tasks in abdominal surgery. Repeated laparotomies, enterocutaneous fistulas, loss of the fascial layer and contaminated operative fields may prevent…
- Trial name
- NCT07326826
- Testing
- Allogeneic non-vascularized rectus abdominis fascial graft (NVRF)
- Volunteers
- 20 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Transplant;Failure,Kidney, Transplant; Failure, Liver
Abdominal Wall Transplant
The purpose of this protocol is to determine the safety and efficacy of abdominal wall transplantation as a treatment for the reconstruction of abdominal wall defects.
- Conditions
- Transplant;Failure,Kidney, Transplant; Failure, Liver, Transplant; Failure, Bowel, Abdominal Wall Defect
- Trial name
- NCT03310905
- Testing
- Abdominal Wall Transplant with another solid organ transplant, Abdominal Wall Transplant alone
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Chronic Pain, Wound Dehiscence
Comparing Polyglactin vs Polypropylene Sutures for Rectus Sheath Closure
This randomized controlled trial aims to compare the outcomes of Polyglactin (Vicryl) versus Polypropylene (Prolene) sutures for rectus sheath closure in patients undergoing midline laparotomy.
- Conditions
- Chronic Pain, Wound Dehiscence, Surgical Site Infection (SSI), Incisional Hernia
- Trial name
- PolySuture (NCT07280975)
- Testing
- Polyglactin 910 (Vicryl) Suture, Polypropylene (Prolene) Suture
- Where
- Pakistan
- Volunteers
- 156 people
- Sponsor
- Lady Reading Hospital, Pakistan
Appendicitis, Hernia
Aromatherapy Versus Acupressure: Impact on Postoperative Pain and Sleep Quality in Pediatric Abdominal Surgery Patients
The study's aim is to examine the effect of using aromatherapy versus acupressure on pain intensity and sleep pattern for children undergoing abdominal surgeries.
- Conditions
- Appendicitis, Hernia, Abdominal Exploration, Splenectomy
- Trial name
- NCT07157501
- Testing
- Accupressure, Aromatherapy inhaler
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Abdominal Hernia
Light vs Heavy Weighted Mesh Repair in Primary Abdominal Hernia in Terms of Surgical Site Infection
This study compares the incidence of surgical site infections (SSI) in patients undergoing abdominal hernia repair using either light or heavy-weighted polypropylene mesh.
- Trial name
- NCT06644612
- Testing
- Light Weight Mesh, Heavy Weight Mesh
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- Khyber Medical University Peshawar
Hernia, Abdominal
Population Based Strategies for Standardized Surgical Care
Evidence-based guidelines to improve clinical care for abdominal wall hernia repair are common, but adherence is low. This proposal aims to evaluate a stakeholder informed Replicating Effective Programs (REP) using a randomized…
- Trial name
- NCT07106541
- Testing
- Replicating Effective Programs (REP), REP with facilitation (REP-PLUS)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Michigan
Ventral Hernia, Incisional Hernia
A Prospective Study of Fortiva in Hernia Repair
The goal of this study is to evaluate safety and performance of the Fortiva Tissue Matrix. Participants will complete questionnaires to measure outcomes after hernia surgery for two years.
- Conditions
- Ventral Hernia, Incisional Hernia, Abdominal Wall Reconstruction
- Trial name
- NCT06101979
- Testing
- Fortiva Tissue Matrix
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- RTI Surgical
Ventral Hernia Repair, Abdominal Hernia
Comparison Between eTEP-RS vs IPOM PLUS
This study aims to compare the outcomes of Enhanced View Totally Extraperitoneal Rives-Stoppa (eTEP-RS) repair and Intraperitoneal Onlay Mesh Plus (IPOM Plus) repair in the management of ventral wall hernias.
- Trial name
- NCT07055464
- Testing
- eTEP-RS Hernia Repair, IPOM Plus Hernia Repair
- Where
- India
- Volunteers
- 174 people
- Sponsor
- GSVM Medical College
Hernia, Ventral, Intestinal Fistula
RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction
The purpose of the study is to compare the clinical outcomes of two commonly used, FDA-approved biologic meshes in hernia repair and abdominal wall reconstruction (Strattice and XenMatrix).
- Conditions
- Hernia, Ventral, Intestinal Fistula, Fibromatosis, Abdominal
- Trial name
- NCT02228889
- Testing
- Abdominal wall reconstruction with Strattice, Assess pain intensity at last office visit preoperatively, Assess pain interference at last office visit preoperatively
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Jeffrey Janis