Clinical trials: Abdominal Hernia
Congenital Diaphragmatic Hernia
North American Fetal Therapy Network Prospective Registry for Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia
The purpose of this research is to determine if babies who undergo a Fetoscopic Endoluminal Tracheal Occlusion (FETO) procedure survive more often and have less long-term complications than babies who have similarly severe…
- Trial name
- NCT07564297
- Testing
- Fetoscopic Endoluminal Tracheal Occlusion, Standard of Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Inguinal Hernia, Abdominal Wall Muscles
Transversus Abdominis Plane Block and Inguinal Hernia Repair
This prospective, randomized, double blinded, placebo-controlled study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided transversus abdominis plane block with ropivacaine 0,75 %, in patients…
- Conditions
- Inguinal Hernia, Abdominal Wall Muscles, Regional Anesthesia, Postoperative Pain
- Trial name
- NCT02030223
- Testing
- Transversus abdominis plane block
- Where
- Greece
- Volunteers
- 59 people
- Sponsor
- Papacharalampous Panagiota
Inguinal Hernia
Comparative Study on the Post-operative Pain and Other Outcomes of Mesh Fixation With Prolene vs Vicryl vs Skin Staples in Lichtenstein Inguinal Hernia Repair.
We are going to see the outcome measures for patient and compare them across two groups, those who are undergoing mesh fixation for inguinal hernia by sutures, and those who are fixated by skin staples.
- Trial name
- NCT07210424
- Testing
- Mesh Fixation
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Herniorrhaphy, Postoperative Pain
Safety and Efficacy of CollaRx® Bupivacaine Implant in Men After Open Laparotomy Herniorrhaphy
This study will assess pain intensity for the first 72 hrs after after aggravated movement (cough)following open laparotomy inguinal herniorrhaphy in patient who receive either the CollaRx Bupivacaine implant or a plain collagen…
- Conditions
- Herniorrhaphy, Postoperative Pain, Inguinal Hernia
- Trial name
- NCT01220024
- Testing
- Bupivacaine Collagen Sponge
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Innocoll
Inguinal Hernia
Flemish Inguinal and Femoral Hernia Prospective Registry
Prospective registry. The purpose of this clinical trial will be to measure surgical outcome parameters (e.g. recurrence, chronic pain and other quality indicators) after inguinal hernia repair using Patient Reported Outcome…
- Trial name
- FLIPR (NCT04623580)
- Testing
- Surgical inguinal or femoral hernia repair
- Where
- 2 sites in Belgium
- Volunteers
- 560 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ventral Hernia
Video-based Collaborative Learning to Improve Ventral Hernia Repair
Recent studies demonstrate the critical role of individual surgeon performance, including both the approach they take to an operation as well as their technical skill, in determining patient outcomes.
- Trial name
- NCT04173884
- Testing
- Coaching, Constructive Feedback
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Gastroschisis
Sutureless vs Sutured Gastroschisis Closure
This study aims to prospectively assess outcomes of sutureless versus sutured gastroschisis closure with a randomized control trial. The parameters of this trial were determined using our retrospective study as pilot data.
- Trial name
- NCT01094587
- Testing
- Gastroschisis closure with suture, Gastroschisis closure without suture
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Stanford University
Inguinal Hernia, Indirect, Postoperative Pain
Comparison of Postoperative Pain After Hernial Sac Ligation Versus Non-ligation in Inguinal Hernioplasty
This study is intends to compare mean postoperative pain scores for 48-hours in patients undergoing Inguinal hernioplasty with and without hernia sac ligation in Department of Surgery, Dow University of Health Sciences \& Dr.
- Trial name
- NCT04079504
- Testing
- Ligation of indirect hernia sac, Non-ligation of Indirect Inguinal hernia sac
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Pain, Postoperative, Hernia, Ventral
An Open-label Safety and Pharmacokinetic Study of INL-001 in Adults Following Various Open Soft-Tissue Surgeries
This is a multicenter, Phase 3, open-label, safety, tolerability, and characterization of pharmacokinetics study of the INL 001 (bupivacaine HCl) implant, at 300 mg, in patients following various soft-tissue surgeries: open…
- Conditions
- Pain, Postoperative, Hernia, Ventral, Abdominoplasty, Hysterectomy
- Trial name
- NCT04785638
- Testing
- INL-001 (bupivacaine hydrochloride) implant
- Where
- 8 sites in United States
- Volunteers
- 100 people
- Sponsor
- Innocoll
Hiatal Hernia
Hiatal Hernia Repair by Tension-free Mesh Closure or Simple Suturing
One-hundred and fifty-nine patients undergoing Nissen fundoplication for symptomatic gastro-oesophageal reflux disease (GORD), who had a concomitant hiatal hernia of > 2 cm axial length, were randomized to closure of the…
- Trial name
- NCT03730233
- Testing
- Hiatal hernia repair by tension-free mesh closure, Hiatal hernia repair by simple suturing
- Volunteers
- 156 people
- Sponsor
- Karolinska Institutet
Ventral Hernia, Adhesions
Comparative Effectiveness Multicenter Trial for Adhesion Characteristics of Ventral Hernia Repair Mesh
The proposed study will compare the benefits, harms, and comparative effectiveness of intraperitoneal barrier-coated and non-barrier coated ventral hernia repair (VHR) mesh in reducing adhesions, adhesion-related complications…
- Trial name
- NCT01355939
- Testing
- Clinically-Indicated Abdominal Re-Exploration Surgery
- Where
- 6 sites in United States
- Volunteers
- 173 people
- Sponsor
- Washington University School of Medicine
Inguinal Hernia
Awake Caudal Catheter vs General Anesthesia
It is well established that preterm inguinal hernias discovered in the NICU pose a significant surgical risk due to the associated co-morbid conditions that accompany these patients.
- Trial name
- NCT05919732
- Testing
- Bupivacaine, Dexmedetomidine, Caffeine, Tylenol, Propofol, rocuronium, caffeine, Tylenol, bupivacaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Congenital Diaphragmatic Hernia
Management of Late Presenting Congenital Diaphragmatic Hernia .
Diagnosis and different ways of surgical repair of Congenital diaphragmatic hernia
- Trial name
- NCT07397793
- Testing
- MIS and open surgery repair
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Jehad Emam Abdelrahman
Inguinal Hernia
A Prospective Study Comparing Telescopic vs. Balloon Dissection in Single Incision Laparoscopic Inguinal Herniorraphy (SILTELESCOPIC)
Our recent prospective randomized controlled study comparing single-port vs. multiport laparoscopic total extraperitoneal inguinal herniorraphy (NCT 01660048) demonstrated superiority of the single-port technique in reducing…
- Trial name
- SILTelescopic (NCT01883115)
- Where
- 2 sites in Australia
- Volunteers
- 102 people
- Sponsor
- The Sydney Hernia Specialists Clinic
Inguinal Hernia Repair, Postoperative Pain
Visually Guided TAP Block in Laparoscopic TAPP Hernia Repair
This prospective, randomized clinical study aims to evaluate the effectiveness of the Transversus Abdominis Plane (TAP) block performed under direct laparoscopic vision in reducing postoperative pain and improving recovery after…
- Conditions
- Inguinal Hernia Repair, Postoperative Pain, TAP Block
- Trial name
- VIS-TAP-TAPP (NCT07264699)
- Testing
- Laparoscopic Transversus Abdominis Plane (TAP) Block with Bupivacaine
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Congenital Diaphragmatic Hernia
Safety and Efficacy of Fetoscopic Endoluminal Tracheal Occlusion in Congenital Diaphragmatic Hernia
The purpose of this study is to evaluate the safety and efficacy of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in cases of severe Congenital Diaphragmatic Hernia (CDH).
- Trial name
- NCT06946576
- Testing
- Fetoscopic Endoluminal Tracheal Occlusion (FETO) Procedure
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Oregon Health and Science University
Ventral Hernia, Abdominal Wall Defect
ExtrAperitoneaL Plasty vs Intraperitoneal oNlay mEsh in Ventral Hernia Repair
This study investigates on the effect of two different operative techniques to treat abdominal wall hernias. The goal of this clinical trial is to learn if the eTEP (Extended totally extraperitoneal repair) technique leads to a…
- Trial name
- ALPINE (NCT06367309)
- Testing
- Extended totally extraperitoneal repair, Intraperitoneal onlay mesh
- Where
- Switzerland
- Volunteers
- 138 people
- Sponsor
- University Hospital, Basel, Switzerland
Umbilical Hernia, TARUP
rTARUP: Long-term Analysis
The aim of the study is to assess the recurrence rate and potential long-term complications, at least 48 months, after a robotic assisted transabdominal retromuscular approach (rTARUP technique) for the repair of an umbilical…
- Conditions
- Umbilical Hernia, TARUP, Robotic Abdominal Wall Surgery
- Trial name
- rTARUP FU (NCT05939206)
- Testing
- rTARUP
- Where
- Belgium
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Inguinal Hernia
Clinical Study of Self-gripping Mesh in TAPP Versus Lichtenstein Hernia Repair
The goal of this prospective study is to compare the clinical efficacy of self-gripping mesh in laparoscopic transabdominal preperitoneal versus Lichtenstein hernia repair, in order to improve the outcome of inguinal hernia…
- Trial name
- NCT06240858
- Testing
- Laparoscopic transabdominal preperitoneal hernia repair., Lichtenstein hernia repair.
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Second Hospital of Jilin University
Ventral Hernia
Regional Differences In Indication for Ventral Hernia Repair
The aim of the present study is to investigate whether there are differences in indication for ventral hernia repair and surgical approach among hernia surgeons from different geographical regions of Denmark.
- Trial name
- NCT02263625
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital