Clinical trials: Abdominal Hysterectomy
Abdominal Hysterectomy (& Wertheim)
Lidocaine and Ketamine in Abdominal Surgery
This study is being done to determine if combined infusions of lidocaine and ketamine is better than a lidocaine or ketamine infusion alone, or to placebo in improving recovery after abdominal hysterectomy.
- Trial name
- NCT00721110
- Testing
- Lidocaine, Ketamine, Ketamine + Lidocaine
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- The Cleveland Clinic
Pain, Postoperative, Anesthesia
Transversus Abdominal Plane Block at Total Laparoscopic Hysterectomy: Effect on Quality of Recovery
The Transversus Abdominal Plane (TAP) block has been used with good success to decrease postoperative pain following laparatomy.
- Trial name
- TAP (NCT01479270)
- Testing
- TAP Block
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Acute Pain Following a Total Abdominal Hysterectomy
A Study of MK0663/Etoricoxib for Post-Abdominal Hysterectomy Surgery Pain (0663-097)(COMPLETED)
The purpose of this study is to evaluate the efficacy and safety of etoricoxib compared to placebo in the treatment of postoperative pain associated with total abdominal hysterectomy.
- Trial name
- NCT00788710
- Testing
- etoricoxib (MK0663) 120 mg, etoricoxib (MK0663) 90 mg
- Volunteers
- 430 people
- Sponsor
- Organon and Co
Post Operative Pain
Ultrasound-guided Transversus Abdominis Plane Block After Hysterectomy
In this randomized, controlled, observer-blinded study we plan to evaluate ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management in patients undergoing abdominal hysterectomy.
- Trial name
- TAP (NCT01153503)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pain, Postoperative, Hysterectomy
Abdominal Ice Packs for Pain Control and Reduction of Narcotic Use Following Laparoscopic Hysterectomy
The purpose of this study is to evaluate the effect of using ice packs on the abdomen immediately after laparoscopic hysterectomy surgery on pain control and narcotic pain medication use.
- Conditions
- Pain, Postoperative, Hysterectomy, Narcotic Use, Cryotherapy Effect
- Trial name
- NCT03341533
- Testing
- Ice packs plus usual post-op analgesia, Usual post-op analgesia
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Mayo Clinic
Hysterectomy (MeSH nr: E04.950.300.399)
Effects of General Anesthesia and Spinal-Morphine Anesthesia on Recovery and Comfort After Benign Abdominal Hysterectomy
The purpose of this study is to determine whether spinal anesthesia combined with intrathecal morphine in abdominal hysterectomy on benign gynecological indications gives better outcome concerning duration of hospital stay and…
- Trial name
- NCT00527332
- Testing
- Bupivacain, Morphine, Propofol
- Where
- 5 sites in Sweden
- Volunteers
- 180 people
- Sponsor
- Preben Kjolhede
Postoperative Pain
EXPAREL Administered Into the TAP for Analgesia in Subjects Undergoing Open Total Abdominal Hysterectomy
The primary objective of this study is to determine the optimal of two different volumes of EXPAREL 266 mg when administered via infiltration into the transversus abdominis plane (TAP) for prolonged postoperative analgesia in…
- Trial name
- NCT01919606
- Testing
- EXPAREL
- Volunteers
- 1 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Pain, Postoperative, Analgesia
Oral Pregabalin as Preemptive Analgesia in Abdominal Hysterectomy
Postoperative pain affects 80% of surgical patients and is one of the main negative symptoms resulting from surgery. It impairs the recovery of patient since it is related to chronic pain, nausea and vomiting and longer hospital…
- Conditions
- Pain, Postoperative, Analgesia, Gabapentin Adverse Reaction, Opioid Abuse
- Trial name
- NCT04495374
- Testing
- Pregabalin 300mg
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Universidade Federal de Alfenas
Pain, Postoperative
Efficacy and Safety of the CollaRx Bupivacaine Implant Compared to the ON-Q Painbuster Following Abdominal Hysterectomy
The purpose of this study is to determine whether the CollaRx Bupivacaine Implant is safe and effective in reducing the amount of narcotic pain medication needed to control pain during the first 96 hours after abdominal…
- Trial name
- NCT00749749
- Testing
- Bupivacaine Collagen Sponge (CollaRx Bupivacaine Implant), ON-Q PainBuster Post-op Pain relief System
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Innocoll
Acute Pain
Oral Treatment for Gynaecological Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride
This study aims to evaluate the analgesic efficacy of single and repeated doses of fixed combination of dexketoprofen trometamol (DKP) and tramadol hydrochloride (TRAM) in comparison to the single agents (and placebo for the…
- Trial name
- DAVID lap (NCT01904149)
- Testing
- Dexketoprofen-single dose, Tramadol-single dose, Dexketoprofen/Tramadol-single dose
- Where
- 28 sites in Hungary, Latvia and 6 more
- Volunteers
- 606 people
- Sponsor
- Menarini Group
Monitoring, Intraoperative
Effects of IV Administration of Ketamine on the Analgesia Nociception Index (ANI) Measured With the PhysioDoloris
This study evaluates effects of the analgesic ketamine on ANI measurements (Anti Nociceptive Index)
- Trial name
- NCT01717521
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Hysterectomy, Postoperative
A Study to Evaluate the Efficacy and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain After Abdominal Hysterectomy
The main objective of this study is to demonstrate the efficacy and safety of multiple-dose application of three different oral doses of CG5503 IR (tapentadol immediate release) compared to placebo in women undergoing abdominal…
- Trial name
- NCT00478023
- Testing
- Morphine, CG5503 IR
- Where
- 52 sites in Hungary, Latvia and 7 more
- Volunteers
- 854 people
- Sponsor
- Grünenthal GmbH
Postoperative Pain
An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Undergoing Hysterectomy
The objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing hysterectomy on the basis of pharmacokinetics, efficacy and safety evaluations.
- Trial name
- NCT00993226
- Testing
- SABER-Bupivacaine Treatment 1a, Bupivacaine HCl Treatment 1c, SABER-Bupivacaine Treatment 2a
- Where
- 14 sites in France, Germany and 4 more
- Volunteers
- 115 people
- Sponsor
- Durect
Endometrial Cancer
Robot Assisted Laparoscopic Hysterectomy vs. Abdominal Hysterectomy in Endometrial Cancer
The purpose of the trial is to determine whether robot assisted laparoscopic hysterectomy compared with abdominal hysterectomy in a fast track program gives a faster recovery postoperatively, causes less tissue damage and less…
- Trial name
- NCT01526655
- Testing
- Abdominal total hysterectomy, Robot assisted laparoscopic hysterectomy
- Where
- 2 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- University Hospital, Linkoeping
Postoperative Pain
TAP Block With Plain Bupivacaine Versus Wound Infiltration With Exparel for Postoperative Pain Management
In this randomized, controlled, observer-blinded study we plan to evaluate pain relief after ultrasound-guided transversus abdominis plane (TAP) block using bupivacaine and wound infiltration using liposomal bupivacaine in…
- Trial name
- NCT02074709
- Testing
- Plain bupivacaine, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hysterectomy
Mixture of Liposomal Bupivacaine and Bupivacaine for TAP Block for Open Hysterectomy
The goal of this study is to evaluate the effectiveness of different formulations of bupivacaine infiltrated into the transversus abdominis plane (TAP) on post-operative pain management after open abdominal hysterectomy.
- Trial name
- NCT03250507
- Testing
- Bupivacaine, Liposomal bupivacaine, Saline
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Henry Ford Health System
Post Operative Pain
Effect of Pregabalin on Post Operative Pain in Abdominal Hysterectomy Under Spinal Anesthesia With Intrathecal Morphine
This study aims to compare the effect of pre-operative oral pregabalin on post operative morphine consumption after abdominal hysterectomy with/without salpingo-oophorectomy.
- Trial name
- NCT02285010
- Testing
- Pregabalin
- Where
- Thailand
- Volunteers
- 125 people
- Sponsor
- Mahidol University
Neuromuscular Blockade, Pain
Recovery After Laparoscopic Hysterectomy With Deep Neuromuscular Blockade and Low Intra-abdominal Pressure
The purpose of this study on laparoscopic hysterectomy is to investigate postoperative pain. Patients are allocated to either deep neuromuscular blockade and low intra-abdominal pressure (8 mmHg) or moderate neuromuscular…
- Conditions
- Neuromuscular Blockade, Pain, Laparoscopy
- Trial name
- NCT01722097
- Testing
- Rocuronium
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- Herlev Hospital
Postoperative Pain
Efficacy and Safety of a Collagen Bupivacaine Implant in Women Following Abdominal Hysterectomy
The purpose of this study is to determine whether the CollaRx Bupivacaine implant is safe and effective in reducing the amount of narcotic pain medication needed to control pain during the first 24 hours after abdominal…
- Trial name
- NCT00624910
- Testing
- Bupivacaine Collagen Sponge (CollaRx®)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Innocoll
Bladder Injury, Complications; Cesarean Section
Cystoinflation to Prevent Bladder Injury in Obstetrics and Gynaecology Surgery
Part1:The healthy pregnant women with previous operative deliveries admitted for elective C-section will be counselled and conditioned informed consent will be taken to be included in either study group if dense pelvic adhesions…
- Conditions
- Bladder Injury, Complications; Cesarean Section, Adhesions Pelvic
- Trial name
- NCT04302545
- Testing
- Cystoinflation
- Where
- Pakistan
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Shazia Saaqib