Clinical trials: Abdominal Infection
Acute Appendicitis
Presentation and Outcomes of Acute Appendicitis During COVID Pandemic
Acute appendicitis (AA) is a frequent cause of acute abdominal pain in emergency rooms around the world [1]. The lifetime risk of developing AA is estimated to be about 8% [1-3].
- Trial name
- AA (NCT05104346)
- Testing
- appendectomy
- Where
- Egypt
- Volunteers
- 1,945 people
- Sponsor
- Mansoura University
Acute Appendicitis
Changes in the Treatment of Acute Appendicitis
The purpose of this study was to analyse the epidemiology, diagnostics, the type of surgical techniques and their development over time, and mortality in acute appendicitis in 68 hospitals in Germany based on routine data between…
- Trial name
- TreatApp (NCT06558760)
- Volunteers
- 31,988 people
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Appendicitis
Morphine Analgesia in Patients With Acute Appendicitis
The purpose of the study is to evaluate morphine effect on pain reduction and diagnostic accuracy in patients admitted to emergency ward with the diagnosis of acute appendicitis.
- Trial name
- NCT00477061
- Testing
- Morphine
- Where
- Iran
- Volunteers
- 71 people
- Sponsor
- Tehran University of Medical Sciences
Other Specified Complications of Pregnancy
Laparoscopic Treatment for Appendicitis During Pregnancy
Acute appendicitis is the most frequent non-obstetric surgical emergency during pregnancy. The benefits of laparoscopy during pregnancy are well known, but complications can occur, and these can affect both the mother and/or the…
- Trial name
- NCT04753502
- Testing
- Laparoscopy
- Where
- Argentina
- Volunteers
- 63 people
- Sponsor
- Austral University, Argentina
Acute Appendicitis in Elderly
Clinicopathological Aspects of Acute Appendicitis in Patients Above Age of Thirty at Sulaimani Emergency Hospital
Aims of this study are : Estimate the incidence of A.A. in patients above age of 30 y in 4 age groups . Correlate between different clinical aspects and histopathological results.
- Trial name
- NCT04033198
- Testing
- Appendectomy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Sulaimani
Antibiotic Prophylaxis, Wound Infection
The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients
This study aims to investigate the impact of antibiotic prophylaxis on reducing wound infection rates following open repair of primary elective groin hernias in high-risk patients.
- Conditions
- Antibiotic Prophylaxis, Wound Infection, Groin Hernia
- Trial name
- NCT06576154
- Testing
- Cefazolin 1000 MG
- Where
- Syria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Gut Microbiota, Intra-abdominal Infections
Gut Microbiota Analysis in IAI Patients With Sepsis-associated Liver Dysfunction
With the rapid development of intensive care medicine, the mortality of patients with sepsis has decreased over the past decade, but it is still the leading cause of death in intensive care unit (ICU).
- Conditions
- Gut Microbiota, Intra-abdominal Infections, Acute Gastrointestinal Injury, Sepsis-associated Liver Dysfunction
- Trial name
- 2022-11-09 (NCT05628493)
- Testing
- Gut microbiota Analysis
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Chinese Medical Association
Peritoneal Dialysis Catheter Infection
Reduction of Exit Site Infection in Peritoneal Dialysis Patients
In peritoneal dialysis patients, the presence of the catheter presents a risk of infection - exit site infection, tunnel infection or peritonitis.
- Trial name
- NCT03798171
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Morbid Obesity, Acidosis
Intraoperative Fluid Management in Laparoscopic Bariatric Surgery
The objective of this study is to evaluate the effects of 'high' versus 'low' volume intraoperative fluid administration (Ringer Lactate, RL) on intra- and postoperative parameters, in obese patients undergoing laparoscopic…
- Conditions
- Morbid Obesity, Acidosis, Intra-Abdominal Abscess, Hemorrhage
- Trial name
- NCT00905502
- Testing
- Lactated Ringer's solution
- Where
- Israel
- Volunteers
- 107 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cytomegalovirus Disease
Cytogam Administration in Abdominal Organ Transplant Recipients at High Risk for Cytomegalovirus Infection
The purpose of the study is to assess the incidence and severity of late Cytomegalovirus (CMV) disease, defined as CMV syndrome or tissue invasive disease occurring between 100 and 200 days and after 200 days post-transplant in…
- Trial name
- NCT01509404
- Testing
- Valganciclovir, CMV hyperimmune globulin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Appendicitis
The Safety and Pharmacokinetics of Intraperitoneal Administration in Patients Undergoing Appendectomy for Uncomplicated Appendicitis
The objective of this trial is to evaluate the safety of the intraperitoneal administration of the combination of fosfomycin, metronidazole, and granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients undergoing…
- Trial name
- NCT03046758
- Testing
- A combination of fosfomycin, metronidazole and GM-CSF i.p.
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Herlev Hospital
Liver Abscess
Characteristics and Treatment Outcome of Liver Abscesses: An Observational Study
1. To assess the frequency, clinical presentation, microbiological and radiological characteristics of liver abscesses. 2. To evaluate the management plan and treatment outcome of liver abscess. 3.
- Trial name
- NCT06852235
- Volunteers
- 70 people
- Sponsor
- Assiut University
Wound Infection, Surgical
Clinical Outcome in View of Surgical Site Infection (SSI) With Antibacterial Skin Sutures
Background: Poor wound healing and the development of surgical site infection (SSI) continue to occur and remain a significant cause of disability among operated patients.
- Trial name
- NCT01540279
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- University Hospital, Basel, Switzerland
Intraabdominal Infections
A Study of Levornidazole Disodium Phosphate for Injection vs. Ornidazole in Treatment of Postoperative Intra-Abdominal Infections Caused by Anaerobic Bacteria
Anaerobic infections are very common in clinical practice. Poor control of anaerobic infections in patients undergoing abdominal surgery may lead to the occurrence of complications.
- Trial name
- NCT06828874
- Testing
- Levornidazole Disodium Phosphate for Injection, Ornidazole and Sodium Chloride Injection
- Where
- 32 sites in China
- Volunteers
- 696 people
- Sponsor
- Yangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Acute Appendicitis
Laparoscopic Assisted or Total Laparoscopic Appendectomy
Acute appendicitis (AA), is a common intra-abdominal surgical pathology with the overall incidence of approximately 7% and mortality of 0.2-0.8%.
- Trial name
- NCT02673528
- Testing
- Laparoscopic appendectomy
- Volunteers
- 451 people
- Sponsor
- Medical Park Gaziantep Hospital
Low Gelsolin, Trauma
Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels
This study is designed to assess the pharmacokinetics and safety of an infusion of a single dose of recombinant plasma gelsolin (rhu-pGelsolin) when given to patients admitted to the Intensive Care Unit with documented low levels…
- Conditions
- Low Gelsolin, Trauma, Infection, Burns
- Trial name
- NCT00671307
- Testing
- rhu-pGelsolin
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Critical Biologics Corporation
Acute Appendicitis, Superficial SSI
Laparoscopic vs Open Appendectomy
his randomized controlled trial was conducted to compare the frequency of superficial surgical site infections (SSIs) following laparoscopic appendectomy and open appendectomy in patients undergoing surgical treatment for acute…
- Trial name
- NCT07841444
- Testing
- Laparoscopic appendectomy, Open Appendectomy
- Where
- Pakistan
- Volunteers
- 276 people
- Sponsor
- Quaid-e-Azam Medical College
Intra-Abdominal Infections, Skin Disease, Infectious
Tygacil Drug Use Investigation
Secondary Data Collection Study; safety and effectiveness of Tigecycline .under Japanese medical practice
- Trial name
- TIGER (NCT01789905)
- Testing
- Tigecycline (Tygacil)
- Volunteers
- 116 people
- Sponsor
- Pfizer
Acute Appendicitis
Endoscopic Retrograde Appendicitis Therapy
This is a prospective pilot study on the efficacy of endoscopic therapy for adult uncomplicated acute appendicitis. In recent years, antibiotics treatment has been a new alternative approach to surgical appendicectomy for acute…
- Trial name
- NCT04281251
- Testing
- Endoscopic retrograde appendicitis therapy
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong