Clinical trials: Abdominal Laparoscopic Surgery, open to volunteers
Neuroblastoma, Ganglioneuroma
Abdominal Neuroblastoma Laparoscopic Surgery Risk Factors Stratification
Surgery plays significant role in treatment of neurogenic tumors, both for benign ganglioneuroma and for high risk neuroblastoma.
- Conditions
- Neuroblastoma, Ganglioneuroma, Ganglioneuroblastoma
- Trial name
- ANLAP-R (NCT06296732)
- Testing
- Duration of surgery intervention
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Cervical Cancer, Hysterectomy
Minimally Invasive Surgery Versus Open Radical Hysterectomy in Presumably Early Stage Cervical Cancer: a Retrospective Multicenter Non-inferiority Study Comparing Overall and Progression-free Survival.
The goal of this retrospective observational study with prospective follow-up is to compare the safety and treatment outcomes of radical laparoscopic hysterectomy (removal of the uterus with cervix) versus abdominal (open)…
- Trial name
- MOOSE (NCT07120529)
- Testing
- CT scan, Ultrasound scan (Transvaginal or Transabdominal), Gynecological examination
- Where
- 5 sites in Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Silesia
Robotic Surgical Procedures, Right Colon Tumors
Comparison of Short- and Long-term Outcomes Between Robotic and Laparoscopic Hemicolectomy of Right Colon Cancer : A Multicenter Propensity Score Matching Analysis
This is a retrospective, multicenter cohort study to compare short- and long-term outcomes between robotic and laparoscopic hemicolectomy of right colon cancer.
- Conditions
- Robotic Surgical Procedures, Right Colon Tumors, Cancer, Laparoscopic Abdominal Surgery
- Trial name
- NCT07029464
- Volunteers
- 4,000 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Neuromuscular Blockade
Comparison of Two Quantitative EMG Monitors for Deep Neuromuscular Block in Laparoscopic/Robotic and VATS Surgery
The main objective of the study is to compare the frequency of intraoperative spontaneous diaphragmatic movements and breath-initiation efforts in participants undergoing robotic and/or thoracic surgery under deep neuromuscular…
- Trial name
- NCT07706504
- Testing
- TetraGraph (Senzime)-Guided Neuromuscular Monitoring (Dominant Hand), TwitchView (Blink)-Guided Neuromuscular Monitoring (Dominant Hand)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Abdominal Laparoscopic Surgery
Application of the Maestro Surgical System for Surgical Assistance in Laparoscopic Abdominal Surgery
This study is designed to evaluate the application of the Maestro Robotic Platform for surgical assistance in laparoscopic abdominal surgery.
- Trial name
- MAESTRO (NCT07858929)
- Testing
- Any abdominal laparoscopic surgery with the usage of the Maestro Platform.
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Laparoscopic Abdominal Surgeries
Effect of Low-dose Pregabalin Retard (82.5 mg) Versus Standard-dose Pregabalin Retard (165 mg) on Postoperative Pain and Opioid Consumption After Elective Laparoscopic Abdominal Surgery
The goal of this clinical trial is to detect whether pregabalin retard (82.5 mg or 165 mg) improves analgesia after elective laparoscopic abdominal surgery in adults. It will also evaluate the safety of both doses.
- Trial name
- NCT07456761
- Testing
- Pregabalin retard 82.5 mg, Pregabalin retard 165 mg
- Volunteers
- 80 people
- Sponsor
- South Egypt Cancer Institute
Elderly Patients, Laparoscopic Surgery
Transnasal Microstream EtCO2 Reduces Hypoxemia During Emergence in Aged Post-Abdomen Surgery
This prospective, randomized controlled study aims to investigate whether transnasal microstream end-tidal carbon dioxide (EtCO₂) monitoring in the post-anesthesia care unit (PACU) reduces the incidence of postoperative hypoxemia…
- Conditions
- Elderly Patients, Laparoscopic Surgery, Postoperative Hypoxemia, Capnography
- Trial name
- NCT07652385
- Testing
- EtCO₂ Monitoring, Routine Monitoring
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Cervical Cancer Stage IB2
Modified Tumor-free Techniques Operation to Cervical Cancer
The goal of this clinical trial is to learn if laparoscopic radical hysterectomy incorporating modified tumor-free techniques (LRH-MTF) works to treat FIGO stage IB2 cervical cancer as good as abdominal radical hysterectomy…
- Trial name
- MOTTO (NCT06836869)
- Testing
- Laparoscopic radical hysterectomy incorporating modified tumor-free techniques, Abdominal radical hysterectomy
- Where
- 17 sites in China
- Volunteers
- 524 people
- Sponsor
- Peking Union Medical College Hospital
Obesity, Obesity, Morbid
Endoscopic Metabolic and Bariatric Therapies
This is a prospective collection of data from adult patients who have had an endoscopic metabolic and bariatric endoscopy procedure (EMBT) for primary or revision surgical procedures for obesity.
- Conditions
- Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate
- Trial name
- EMBTs (NCT05725967)
- Testing
- Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Christopher C. Thompson, MD, MSc
Oncologic Surgery, Cancer
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery.
- Conditions
- Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer
- Trial name
- LapTAP (NCT06731998)
- Testing
- Local Anesthesia, Laparoscopic Transversus Abdominis Plane block
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Hypotension During Surgery
Effect of Titrated Administration of Ciprofol on Perioperative Hypotension in Elderly Patients Undergoing Laparoscopic Abdominal Surgery: A Randomized Controlled Trial
Elderly patients are frequently burdened with age-associated comorbidities and frailty, accompanied by physiological changes such as vascular stiffening, cardiac dysfunction, and impaired autonomic regulation.
- Trial name
- TAPH (NCT07328958)
- Testing
- titrated anesthesia
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Postoperative Pain
Tegileridine vs Sufentanil for Postoperative Pain Management and Gastrointestinal Recovery After Major Laparoscopic Abdominal Surgery
This study is a single-center, randomized, triple-blind clinical trial designed to compare tegileridine and sufentanil for postoperative analgesia and gastrointestinal tolerability in patients undergoing major laparoscopic…
- Trial name
- TASPER (NCT07637968)
- Testing
- Tegileridine, Sufentanil, Palonosetron
- Volunteers
- 84 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Gastric Adenocarcinoma, Laparoscopic Gastrectomy
Feasibility of Enhanced Recovery After Surgery Without Prophylactic Abdominal Drainage Tubes After Laparoscopic Distal Gastrectomy For Gastric Cancer
This study aims to compare the effects of using prophylactic abdominal drainage tubes during Enhanced Recovery After Surgery (ERAS) in patients undergoing Laparoscopic Distal Gastrectomy (LDG) for gastric cancer through a…
- Conditions
- Gastric Adenocarcinoma, Laparoscopic Gastrectomy, Complications
- Trial name
- NCT07029269
- Testing
- ERAS-tubeless group, ERAS-tube group
- Where
- 6 sites in China
- Volunteers
- 454 people
- Sponsor
- Zuoyi Jiao
Fraily, Abdominal Surgery
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
This is a bicentric, prospective, non-pharmacological, randomized study designed to compare the efficacy and safety of awake neuraxial anesthesia with sedation versus general anesthesia in frail patients undergoing elective major…
- Conditions
- Fraily, Abdominal Surgery, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- SAFE-AWARENESS (NCT07486336)
- Testing
- Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Oxycodone, Chronic Pain, Postoperative
Effect of Preventive Analgesia with Oxycodone and Parecoxib Sodium on the Chronification of Acute Post-operative Pain
The goal of this clinical trial is to learn if the administration of oxycodone for preventive analgesia works to reduce the chronification of acute postoperative pain in adult participants undergoing major abdominal surgery.
- Trial name
- AOPC (NCT06721988)
- Testing
- oxycodone and parecoxib sodium combinations
- Volunteers
- 1,316 people
- Sponsor
- Ailin Luo
Perioperative Hypothermia, Hernia, Inguinal
Effect of Laryngeal Mask Airway vs Endotracheal Tube on Hypothermia in Laparoscopic Hernia Surgery
This study aims to compare the effects of a laryngeal mask airway (i-gel) and an endotracheal tube on perioperative hypothermia in patients undergoing laparoscopic inguinal hernia surgery.
- Trial name
- LMA-HYPOTH (NCT07913841)
- Testing
- i-gel Supraglottic Airway Device, Endotracheal Tube
- Volunteers
- 256 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Abdominal Surgery, Postoperative Pain
External Oblique Intercostal Plane Block for Postoperative Analgesia After Major Upper Abdominal Surgery
Postoperative pain after laparoscopic major upper abdominal surgery (e.g., gastric, hepatic, gallbladder, pancreatic surgery) is often severe, and inadequate analgesia may lead to increased opioid use, opioid dependence, and poor…
- Trial name
- NCT07331441
- Testing
- External Oblique Intercostal Plane Block, Standard multimodal analgesia
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Jun Zhang
PCV-VG Versus VCV Ventilation Mode Effects on Hemodynamics
Effect of Pressure-Controlled Volume Guaranteed Versus Volume-Controlled Ventilation Modes on Hemodynamic Outcomes e.g ( SV, CO ) and Respiratory Mechanics During Laparoscopic Abdominal Cancer Surgeries With Exaggerated Trendelenberg Postion
The primary outcome is to compare the hemodynamic outcomes ( e.g SV , CO and CI ) using The ICON of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated…
- Trial name
- NCT07550738
- Testing
- electrical cardiometry ('ICON CARDIOTRONIC, OSYPKA MEDICAL') , Lung ultrasonography (LUS) for atelectasis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University