Clinical trials: Abdominal Obesity
Abdominal Obesity, Insulin Resistance
Effects of Acipimox on Mitochondrial Function in Obesity
The purpose of the study is to examine whether a medication called acipimox can improve your body's mitochondria. Mitochondria are the "power house" of the cell and make energy for your body.
- Conditions
- Abdominal Obesity, Insulin Resistance, Hypertriglyceridemia
- Trial name
- NCT01488409
- Testing
- Acipimox
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Massachusetts General Hospital
Hypogonadism
Efficacy and Tolerability of Testogel/Nebido in Combination With Exercise and Diet in Hypogonadal Male Patients
With advancing age testosterone levels decline in men. Low testosterone levels plus certain symptoms are called "Late Onset Hypogonadism (LOH)". Adipose tissue may contribute to testosterone deficiency.
- Trial name
- NCT00847314
- Testing
- Testosterone Undeconate (Nebido-R, BAY86-5037)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Bayer
Diabetes Mellitus, Type 2, Obesity
Culturally Adapted Dietary Clinical Trial in PR
This project will determine whether a diet culturally adapted to adults in Puerto Rico can effectively decrease cardiometabolic risk factors.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Dyslipidemias
- Trial name
- PRECISION (NCT05962372)
- Testing
- Culturally tailored food and diet advice, Standard healthy eating advice
- Where
- Puerto Rico
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Abdominoplasty Surgery
Correlation Between Intra-abdominal Pressure and Diaphragmatic Mobility in Women Submitted to Abdominoplasty After Bariatric Surgery
Background: Plication of the rectus abdominis muscles leads to an increase in intra-abdominal pressure (IAP), which may negatively impact the respiratory system due to its effects on diaphragmatic mobility (DM).
- Trial name
- NCT06648694
- Testing
- Abdominoplasty surgery, Abdominoplasty
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Obesity
Bioimpedance Analysis for Follow-up of Dieters
Prospective, single arm, dietary intervention study.
- Trial name
- BIA (NCT02975427)
- Testing
- Diet group
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Baskent University Ankara Hospital
Thymoma, Mediastinal Tumor
Clinical Investigation of the da Vinci Surgical System
This prospective, multicenter, single-arm study is being conducted to confirm safety, effectiveness, and usability of da Vinci Surgical System in performing robotic-assisted surgical procedures.
- Conditions
- Thymoma, Mediastinal Tumor, Gynecologic Disease, Gynecologic Cancer
- Trial name
- NCT05682742
- Testing
- Robotic-assisted Surgery
- Where
- 4 sites in United States
- Volunteers
- 53 people
- Sponsor
- Intuitive Surgical
Obesity, Visceral, Obesity
Genes Variability in Obesity and Normal Body Weight Patients.
The goal of this clinical trial is to learn about variability of gene SCD and MT-ATP6 in describe participant population and health conditions.
- Trial name
- NCT05789888
- Testing
- MT-ATP6 mtDNA gene variability in obesity and normal body weight patients., SCD gene variability in obesity and normal body weight patients., Finding TOFI and FOTI phenotypes in participants with obesity and normal weight.
- Where
- Poland
- Volunteers
- 116 people
- Sponsor
- Medical University of Bialystok
Uncomplicated Ventral Incisional Hernia, Obesity
ProSpectic Italian Laparoscopic Hybrid mEsh hErnia Repair in Obese patientS Trials
The aim of this study is to evaluate safety and effectiveness of a hybrid mesh (GORE® SYNECOR Intraperitoneal Biomaterial) in patients with a BMI of 30 kg/m2 or more undergoing laparoscopic ventral hernia repair (LVHR) with…
- Trial name
- PSICHE-EROS (NCT05632952)
- Testing
- Intraperitoneal Onlay Mesh positioning Plus
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Obesity, Dyslipidemia
Effect of Abdominal Obesity on Lipoprotein Metabolism
Abdominal obesity is strongly associated with dyslipidemia, which may account for the associated increased risk of atherosclerosis and coronary disease.
- Conditions
- Obesity, Dyslipidemia, Insulin Resistance
- Trial name
- NCT00438061
- Testing
- Weight loss by dietary restriction
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Western Australia
Obese Individuals, Central Adiposity
Post-exercise Blood Pressure With Inorganic Nitrate
This study is examining whether acute inorganic nitrate supplementation in the form of beetroot juice, paired with an acute bout of exercise, affects blood pressure and what is the magnitude of the difference compared to exercise…
- Trial name
- BEET-DOWN (NCT07869472)
- Testing
- Beetroot Juice - Active + Exercise, Beetroot Juice - Active + No exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Abdominal Obesity, Metabolic Syndrome
Diet, Exercise, Metabolism, and Obesity in Older Women
Reductions in fat oxidation and resting metabolic rate (RMR) are associated with normal aging and are accelerated with menopause.
- Trial name
- DEMO (NCT00664729)
- Testing
- Caloric Restriction, Caloric Restriction + Low-Intensity aerobic exercise, Caloric Restriction plus High-intensity aerobic exercise
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity, Microalbuminuria
Evaluation of the Rimonabant Impact on the Regression of Asymptomatic Damage Caused by Cardiovascular Risk Factors
Primary objective: To assess the effect on microalbuminuria levels of treatment with rimonabant 20 mg versus a placebo during a 12 month period.
- Conditions
- Obesity, Microalbuminuria, Diabetes Mellitus, Type 2, Dyslipidemia
- Trial name
- RIALTO (NCT00458081)
- Testing
- Rimonabant
- Where
- Spain
- Volunteers
- 174 people
- Sponsor
- Sanofi
Glucose Intolerance, Obesity
Clinical Trial to Assess the Effects of Candesartan on the Carbohydrate Metabolism of Obese Subjects
Hypothesis: The use of candesartan 16-32 mg/d for 6 months improves the carbohydrate metabolism, and decreases the plasmatic levels of adipocytokines and oxidative stress markers, in non diabetic, non hypertensive subjects with…
- Trial name
- ARAMIA (NCT00319202)
- Testing
- Candesartan
- Where
- Colombia
- Volunteers
- 56 people
- Sponsor
- Fundación Cardiovascular de Colombia
Obesity, Abdominal, Metabolic Syndrome
Omega-3 PUFA in Prevention of Cardiovascular and Metabolic Diseases (CARDMET3)
The study is aimed to assess the efficacy of animal, plant sources of omega-3 polyunsaturated fatty acids and omega-3 pharmacological supplements on obesity, metabolic syndrome and cardiovascular disease.
- Conditions
- Obesity, Abdominal, Metabolic Syndrome, Cardiovascular Risk Factor
- Trial name
- CARDMET3 (NCT04208308)
- Testing
- Chia seeds supplementation (25 g), Chia seeds supplementation (15 g), Combine supplementation: chia seeds (15g) and fish oil Maxi Cor 70+20
- Where
- Slovakia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pavol Jozef Safarik University
Weight Loss, Abdominal Obesity
Highest Weight Loss and Abdominal Adiposity Loss With Hypocaloric Diet Plan and Auricular Acupuncture
The implications of obesity, especially visceral fat, in health are well known. It would be desirable to control obesity by safe and effective treatment modalities.
- Trial name
- NCT04834180
- Testing
- Hypocaloric diet plan, Auricular Acupuncture, Acupressure
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Andreia Vieira
Obesity, Type 2 Diabetes
Evaluation of Intra-Abdominal Fat in Patients With Type 2 Diabetes Using a Non-Invasive Method
The main aim of this study is to compare 2 different measurements of visceral fat that can be easily used in clinical practice (waist circumference versus bioelectric impedance) in relation to known risk factors of coronary…
- Conditions
- Obesity, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT01283113
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Joslin Diabetes Center
Laparoscopic Surgical Procedure, Obesity
Previous Abdominal Surgery and Obesity Does Not Affect Unfavorably the Outcome of Total Laparoscopic Hysterectomy
Previous surgery and obesity has disputed as an unfavorable factor during Total Laparoscopic Hysterectomy. The aim of the investigator's study was to assess the effects of previous abdominal surgery and obesity on intra-operative…
- Conditions
- Laparoscopic Surgical Procedure, Obesity, Surgery--Complications
- Trial name
- NCT03738085
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Ankara University
Insulin Resistance, Obesity
Surgical Removal of Visceral Fat Tissue (Omentectomy) Associated to Bariatric Surgery: Effects on Insulin Sensitivity
The intraabdominal fat is associated with insulin resistance, a condition that is in the basis of diabetes, metabolic syndrome and some cardiovascular diseases.
- Conditions
- Insulin Resistance, Obesity, Metabolic Syndrome X
- Trial name
- NCT00545805
- Testing
- Roux-en-Y Gastric Bypass plus total omentectomy, Roux-en-Y Gastric Bypass
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Campinas, Brazil
Mitral Valve Insufficiency
Determinants of the Progression and Outcome of Mitral Regurgitation
Mitral regurgitation (MR) is one of the most frequent valve lesions, both in North America and in Europe, and its prevalence is increasing with the aging of the population.
- Trial name
- PROGRAM (NCT01835054)
- Testing
- Blood biomarkers, DNA collection, Echocardiography
- Where
- 4 sites in Belgium, Canada and 1 more
- Volunteers
- 440 people
- Sponsor
- Laval University
Surgical Site Infection, Gynecologic Cancer
Effectiveness of Wound Drains for the Prevention Of Surgical sITe infectION
The aim of the present randomized trial is to assess the efficacy of wound drains in terms of reducing the rates of surgical site infection in obese patients with gynecological cancer.
- Conditions
- Surgical Site Infection, Gynecologic Cancer, Wound Drain
- Trial name
- POSITION (NCT05179122)
- Testing
- Surgical drain
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens