Clinical trials: Abdominal Obesity, active
Ventral Hernia
Bariatric SUrgery With Mesh REpair of Ventral Hernia: a Randomized Controlled Trial
The primary objective of the study is to demonstrate that hernia recurrence (VH) repair with non absorbable mesh concomitant to Bariatric Surgery (BS) decreases the risk of VH, with or without surgical repair, during the first…
- Trial name
- BeSURE (NCT05488288)
- Testing
- Mesh repair, Suture repair
- Where
- France
- Volunteers
- 354 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abdominal Obesity, Postoperative Pain
Transversus Abdominis Plan Block Versus Rectus Sheath Block
The investigator aims to compare the analgesic efficacy of Transversus Abdominis Plan Block and Rectus Sheath Block which are used to prevent intraoperative and postoperative pain and reduce the use of opioid in abdominoplasty…
- Conditions
- Abdominal Obesity, Postoperative Pain, Postoperative Complications
- Trial name
- NCT06897345
- Testing
- transversus abdominis plane block, rectus sheat block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Metabolic Syndrome, Insulin Resistance
EFFECTS OF OLEUROPEIN ON BLOOD PARAMETERS AND INFLAMMATORY MARKERS IN ADULTS WITH METABOLIC SYNDROME
The aim of this study is to determine the effect of 6 weeks supplementation of oleuropein on individuals diagnosed with metabolic syndrome.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Obesity, Abdominal, Obesity
- Trial name
- NCT06673914
- Testing
- Control Group: Diet Group, Oleuropein and Diet Group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Atlas University
Dyslipidemias, Obesity
Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity
The major objective of this project is to examine whether daily consumption of milk polar lipids (MPLs) influences cardiometabolic risk factors.
- Trial name
- NCT05700916
- Testing
- Milk Polar Lipid-Rich Dairy Powder, Dairy Powder
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Obesity
Effect of Non-invasive Vagal Nerve Stimulation on Selected Outcomes in Central Obesity
Trans Cutanous Electric Nerve Stimulation of Auricular Vagus Nerve
- Trial name
- NVN-CO (NCT07341971)
- Testing
- Transcutanous Auricular vagus nerve stimulation
- Volunteers
- 60 people
- Sponsor
- Cairo University
Overweight and Obesity, Metabolic Syndrome
Testing the Adipose Expandability Hypothesis In Vivo During Overfeeding
Adipose, or fat, tissue is a plastic organ that retains the ability to expand and store excess calories during positive energy balance in humans.
- Trial name
- EAT 2 (NCT04583514)
- Testing
- Control, Overfeeding
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity, Abdominal, Diabetes
Exploratory Evaluation of the Effect of Cholestyramine on Serum Levels of POPs in Obese Female Patients
Environmental endocrine disruptors (EDCs) represent a major problem for human health.Some PEEs can accumulate in the fatty tissue of the human body thanks to their lipophilic nature, and are known as persistent organic pollutants…
- Conditions
- Obesity, Abdominal, Diabetes, Bariatric Surgery Candidate
- Trial name
- OBESE (NCT05966727)
- Testing
- Cholestyramine Powder
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Obesity and Obesity-related Medical Conditions, Sarcopenic Obesity
Changes in Fat and Muscle Tissue Function and Their Impact on Metabolic Health After Bariatric Surgery
This prospective, single-center observational cohort study aims to explore the relationship between skeletal muscle quality, fat distribution, and metabolic health in Chinese patients with obesity, and to evaluate how bariatric…
- Conditions
- Obesity and Obesity-related Medical Conditions, Sarcopenic Obesity, Adipose Tissue, Abdominal
- Trial name
- NCT07035483
- Testing
- bariatric surgery
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shaihong Zhu
Abdominal Muscles Strength, Abdominal Muscles Endurance
Combined Effects of Dead Bug Exercise and Double Straight Leg Raises Versus Conventional Physical Therapy Exercise on Core Stability and Waist Circumference in Healthy Young Individuals
Increased sedantry lifestyle has caused a decrese in core stability. Moreover alongwith sedantry lifestyle unhealthy eating habits have also increased causing an increase in abdominal adiposity and waist circumference.
- Conditions
- Abdominal Muscles Strength, Abdominal Muscles Endurance, Abdominal Muscles Flexibility, Waist Circumference
- Trial name
- NCT07467044
- Testing
- Combination of Dead Bug Exercise and Double Straight Leg Raises, Abdominal stretches
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Visceral Obesity, Metabolic Syndrome
Polygonatum Sibiricum Reduces Visceral Fat in Obese Adults
This study is being done to find out if a traditional Chinese herb called Polygonatum sibiricum (Huangjing) can help reduce belly fat and improve metabolic health in adults with visceral obesity.
- Trial name
- NCT07759323
- Testing
- Polygonatum sibiricum, Lifestyle Intervention
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhejiang Provincial Tongde Hospital
Central Obesity
Effect of Ultrasound Cavitation on Insulin Resistance in Patients with Central Obesity in Female
The purpose of this study was to investigate the effect of ultrasound cavitation on insulin resistance, HbA1c and skin fold in patients with abdominal central obesity.
- Trial name
- NCT06729203
- Testing
- Ultrasound cavitation, Exercise
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Fitness Trackers, Cardio Vascular Disease
Effects of Wearable Device Functions and Health Coaching on Device-measured Movement Behaviours and Cardiometabolic Risk Factors in Adults With Central Obesity
This study is a randomized controlled trial. The objective of this study is to investigate: 1. the effects of 1-year evidence-based interventions incorporating wearable device functions alone on device-measured movement…
- Conditions
- Fitness Trackers, Cardio Vascular Disease, Physical Activities, Exercise
- Trial name
- NCT07379970
- Testing
- Fitbit Wearable Device, Lifestyle Coaching Program
- Where
- Hong Kong
- Volunteers
- 133 people
- Sponsor
- The University of Hong Kong
Abdominal Aortic Aneurysm, Morbid Obesity
Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH)
The aim of the study is to describe the effectiveness of Optilene® Silver Mesh Elastic on prevention of surgical site infection (SSI) at 6 months follow-up in patients undergoing urgent laparotomy by collecting clinical data on…
- Trial name
- SSIHLVER (NCT06547138)
- Testing
- Prophylactic mesh
- Where
- 5 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Aesculap AG
Diet, Healthy, Obesity, Visceral
NUTritional Impact of a Hypocaloric Hyperprotein Diet Before Obesity Surgery
Obesity is a major public health problem and is constantly on the rise. Therapeutic approaches based on dietary advice, physical activity and the management of psychological difficulties are not always sufficient to achieve a…
- Conditions
- Diet, Healthy, Obesity, Visceral, Bariatric Surgery Candidate
- Trial name
- NUTRACOB (NCT04942093)
- Testing
- With low-calorie, high-protein diet, Without low-calorie, high-protein diet
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Rouen
Obesity, Abdominal, Adiposity
Transcriptional Changes in Isolated Human Adipocytes During Obesity
Adipocytes play an important role in our body through their function as metabolic energy stores in the form of fat deposits, which are stored when metabolic energy is in excess and released when energy levels are low.
- Trial name
- NCT06907212
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Lifestyle, Healthy, Muscle Weakness
RE-inventing Strategies for Healthy Ageing; Recommendations and Tools
The goal of the RESTART RCT is to examine whether a complex lifestyle intervention, coordinated with municipal and non-government organizations (NGO), can establish and preserve improvements in risk factors and functional…
- Conditions
- Lifestyle, Healthy, Muscle Weakness, Abdominal Obesity, Cardiometabolic Syndrome
- Trial name
- RESTART (NCT06122441)
- Testing
- Complex lifestyle intervention, Physical activity monitoring and recommendations
- Where
- Norway
- Volunteers
- 119 people
- Sponsor
- University of Tromso
Thymoma, Mediastinal Tumor
Clinical Investigation of the da Vinci Surgical System
This prospective, multicenter, single-arm study is being conducted to confirm safety, effectiveness, and usability of da Vinci Surgical System in performing robotic-assisted surgical procedures.
- Conditions
- Thymoma, Mediastinal Tumor, Gynecologic Disease, Gynecologic Cancer
- Trial name
- NCT05682742
- Testing
- Robotic-assisted Surgery
- Where
- 4 sites in United States
- Volunteers
- 53 people
- Sponsor
- Intuitive Surgical
Central Obesity
Cavitaion vs W-BEMS on Central Obesity
The purpose of this study is to compare the effects of ultrasound cavitation and whole-body electromyostimulation (WB-EMS) on inflammatory markers in individuals with central obesity.
- Trial name
- w-bems (NCT07307898)
- Testing
- cavitation, whole body electromyostimulation
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ventral Hernia, Surgery
STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair
The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes.
- Conditions
- Ventral Hernia, Surgery, Risk Reduction, Lifestyle
- Trial name
- STRONG-Hernia (NCT06611462)
- Testing
- Prehabilitation (the STRONG programme)
- Where
- 3 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Bispebjerg Hospital
PostoperativePulmonaryComplications
A Multicenter Randomized Controlled Clinical Trial of the Impact of Minimally Invasive Abdominal Surgery Esophageal Pressure Monitoring Guided Individualized PEEP on Postoperative Pulmonary Complications in Obese Patients
The aim of this study is to compare the effect of individualized PEEP based on transmural lung pressure and fixed PEEP on postoperative pulmonary complications during laparoscopic or robotic abdominal surgery in obese patients.
- Trial name
- NCT06996288
- Testing
- Transpulmonary pressure-guided individualized PEEP
- Volunteers
- 180 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital