Clinical trials: Abdominal Surgeries
Chronic Postoperative Pain
Effect of Intraoperative Dexmedetomidine on Postoperative Pain in Elderly Patients Undergoing Major Abdominal Surgery: a Secondary Analysis Based on Prospective Data
This study is a secondary analysis of multicenter prospective data, including elderly patients who underwent elective major abdominal surgery between April 2020 and April 2022 from a perioperative database of elderly patients in…
- Trial name
- NCT07744308
- Where
- China
- Volunteers
- 2,754 people
- Sponsor
- Chinese PLA General Hospital
Pain, Postoperative
US-guided Thoracic Spinal Epidural Anesthesia VS GA for Abdominal and Breast Surgeries
Ultrasound-guided combined thoracic segmental spinal epidural anesthesia in comparison with general anesthesia in upper abdominal and breast surgery.
- Trial name
- NCT05587608
- Testing
- combined thoracic segmental spinal epidural anesthesia
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- South Egypt Cancer Institute
Postoperative Respiratory Complication
Postoperative Pulmonary Complications in Robotic Versus Non-robotic Laparoscopic Surgery
This secondary analysis aims to identify factors associated with the development of postoperative pulmonary complications (PPCs) in patients undergoing abdominal surgery, pooling and analyzing the data of two worldwide…
- Trial name
- LapRas (NCT06234774)
- Testing
- Robot-assisted laparoscopic surgery, Conventional (non-robotic) laparoscopic surgery
- Volunteers
- 2,378 people
- Sponsor
- University of Genova
Pain Management, Postoperative Care
The Effect of the Strategic Game Tangram on Postoperative Patient Outcomes
The aim of this study was to investigate the effects of playing tangram game after surgery on pain, fatigue and comfort levels in patients undergoing abdominal surgery.
- Conditions
- Pain Management, Postoperative Care, Nursing Care
- Trial name
- NCT07031271
- Testing
- Tangram game
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Aydin Adnan Menderes University
Colorectal Neoplasms
Immunotoxin in Peritoneal Carcinomatosis- ImmunoPeCa Trial
The purpose of this study is through a phase I/II clinical trial to assess the safety and toxicity of intraperitoneally administered MOC31PE immunotoxin, given on the 1.postoperative day after cytoreductive surgery (CRS) and…
- Trial name
- ImmunoPeCa (NCT02219893)
- Testing
- MOC31PE Immunotoxin
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Delirium
Autonomic Cardiovascular Control for Elderly Surgery Patients
The purpose of this study is to study aspects of autonomic cardiovascular control and the level of stress hormones and inflammatory markers in saliva or serum, in elderly patients exposed to elective, major abdominal surgery…
- Trial name
- NCT01698125
- Testing
- Abdominal surgery
- Where
- Norway
- Volunteers
- 3 people
- Sponsor
- Oslo University Hospital
Hernia, Incisional Hernia
"Nanotechnologies Applied to General Surgery and Emergency Surgery: Buckypaper as a New Fixing Method for Prosthetic Materials for the Treatment of Hernia and Incisional Hernia in Laparotomy and Laparoscopic
"Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias, diaphragmatic hernias, diaphragmatic rupture…
- Trial name
- 36P (NCT02137018)
- Testing
- PPL fixation by BP, PPL mesh
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Anxiety
Effect of Informing Family Members of Patients During Surgery
Psychological and physiological issues encountered by family members due to the intraoperative process are factors that complicate the support and care systems of the patient.
- Trial name
- NCT06723600
- Testing
- Information
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Pain, Postoperative, Hernia, Ventral
An Open-label Safety and Pharmacokinetic Study of INL-001 in Adults Following Various Open Soft-Tissue Surgeries
This is a multicenter, Phase 3, open-label, safety, tolerability, and characterization of pharmacokinetics study of the INL 001 (bupivacaine HCl) implant, at 300 mg, in patients following various soft-tissue surgeries: open…
- Conditions
- Pain, Postoperative, Hernia, Ventral, Abdominoplasty, Hysterectomy
- Trial name
- NCT04785638
- Testing
- INL-001 (bupivacaine hydrochloride) implant
- Where
- 8 sites in United States
- Volunteers
- 100 people
- Sponsor
- Innocoll
Postoperative Pulmonary Complications (PPCs)
Perioperative Prophylactic Positive Pressure Ventilation Reduces Postoperative Pulmonary Complications.
The incidence of postoperative pulmonary complications (PPCs) ranges from 5% to 33%. PPCs significantly prolong hospital stay, increase the economic burden, and are associated with postoperative mortality at 30 days and 1 year.
- Trial name
- NCT07461285
- Testing
- Conventional Ventilation, Perioperative positive pressure ventilation
- Volunteers
- 206 people
- Sponsor
- Jun Zhang
Surgery, Anxiety
The Effect of Preoperative Education on Anxiety
This randomized controlled study aimed to evaluate the effect of preoperative education on anxiety levels in patients undergoing abdominal surgery at a training hospital in Istanbul.
- Trial name
- Anxiety (NCT06629571)
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Marmara University
Surgery, Recovery
Postoperative Quality Recovery Scale (PQRS)
Recovery following general anesthesia and surgery is a complex issue confounded by the type of surgery, surgical care, inflammation, different anesthetic drugs and techniques, patient co-morbidities, and differing patient and…
- Trial name
- NCT01902147
- Testing
- Postoperative Quality Recovery Scale (PQRS)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Franco Carli
Acute Postoperative Pain
Combined Epidural Morphine and Midazolam on Postoperative Pain
this study aim to Compare the effect of preoperative Epidural Midazolam, Morphine and their combination in postoperative pain relief and total morphine consumption.
- Trial name
- NCT04033471
- Testing
- midazolam
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Open Abdominal Surgery
Intrathecal Morphine for Quality of Recovery After Open Abdominal Surgery Within an Enhanced Recovery Pathway
Pain management after open abdominal surgery still faces severe challenges, with the incidence of moderate to severe pain after surgery as high as 50 - 90%.
- Trial name
- NCT07575321
- Testing
- Intrathecal Morphine, Intrathecal saline injection, TAPB
- Volunteers
- 756 people
- Sponsor
- Sun Yat-sen University
Abdominal Obesity, Obesity
Suture Length Effects in Acupoint Implantation for Abdominal Obesity
Obesity is a metabolic disorder and has become a global health issue with a steadily increasing prevalence. According to the Health Promotion Administration's statistical report, the overweight and obesity rate among adults in…
- Trial name
- NCT07125716
- Testing
- 1 inch, 0.5 inch
- Where
- Taiwan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Pain
Comparison of Patient Controlled & Continuous Epidural Analgesia in Thoraco-abdominal Surgeries in Cancer Patients
This study aims to compare the efficacy of pain control, the consumption of local anesthetic and opioids, side effects, and patient satisfaction between continuous epidural infusion and patient controlled epidural analgesia after…
- Trial name
- NCT02803385
- Testing
- Continous Epidural Analgesia, Patient Controlled Epidural Analgesia
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Tata Memorial Centre
Major Elective Abdominal and Thoracic Surgery
Evaluation of Glycocalyx in Major Abdominal and Thoracic Surgery
Background: The glycocalyx is a fundamental component of the endothelial barrier and alterations at this level have been shown to exacerbate the inflammatory response in the microcirculation.
- Trial name
- NCT04900779
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Surgical Site Infection
INtestinal Dysbiosis and TRanslocation of Bacteria in Patients Undergoing Surgery
The goal of this observational study is to contribute to a better understanding of the perioperative kinetics of intestinal microbial composition and association with surgical site infections.
- Trial name
- INTRA (NCT05775341)
- Testing
- No Intervention
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ventral Hernia
Microlyte in Prevention of SSI After Open Ventral Hernia Repair
Participants who are scheduled to have open ventral hernia repair (OVHR) will be asked to take part in this study. The purpose of this study is to find out if placing Microlyte (which is a dissolvable sheet coated in silver) on…
- Trial name
- NCT05093894
- Testing
- Group 1
- Where
- 3 sites in United States
- Sponsor
- Prisma Health-Upstate
Acute Abdomen
Upper Gastrointestinal Perforations: a Nationwide Registry-based Study
The primary aim of this project is to increase the knowledge about how perforations in the esophagus, stomach and small intestine are treated on a national level.
- Trial name
- NCT06154603
- Testing
- Surgical treatment type
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Stockholm