Clinical trials: Abdominal Wall Defect
Hernia
Safety Study of MotifMESH (cPTFE) in Abdominal Surgery
This study will monitor surgically repaired large abdominal hernias requiring condensed fenestrated polytetrafluoroethylene mesh (cPTFE).
- Trial name
- NCT01364233
- Testing
- MotifMESH
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medline Industries
Gastroschisis
Fetal Repair of Complex Gastroschisis: A Safety and Feasibility Trial
The goal of this clinical trial is to evaluate the safety and feasibility of fetal repair of complex gastroschisis (GS) via a fetoscopic surgical approach by assessing maternal, fetal, neonatal, and infant outcomes in a cohort of…
- Trial name
- NCT05704257
- Testing
- fetoscopy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Abdominal Wall Defect, Incisional Hernia
Change in Fascial Tension in Open Abdomens
The goal of this observational study is to quantitatively measure the change in tension of the abdominal wall over time in subjects with open abdomens using a tensiometer.
- Trial name
- NCT05579652
- Testing
- Abdominal tension measurement
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Benjamin T. Miller
Abdominal Wall Defect
Study to Evaluate Reduction in Pain After Laparoscopic Hernia Repair With Mesh Soaked in Bupivacaine Solution
Early post-operative pain and discomfort after laparoscopic repair remains a concern for patients requiring hospital stay and parenteral narcotic analgesics .
- Trial name
- HAPPIEST (NCT03035617)
- Testing
- Bupivacaine, Saline
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Aga Khan University
Incisional Hernia, Ventral Hernia
Risk Factors for Mesh Infection After Abdominal Wall Reconstruction
Abdominal wall reconstruction (AWR) with mesh is the standard repair for ventral, incisional, parastomal and complex abdominal wall defects, but mesh-related infection remains one of its most serious complications - prolonging…
- Conditions
- Incisional Hernia, Ventral Hernia, Parastomal Hernia, Abdominal Wall Defect
- Trial name
- NCT07725718
- Where
- Egypt
- Volunteers
- 420 people
- Sponsor
- Minia University
Abdominal Wall Defect, Abdominal Wall Injury
Safety and Clinical Performance of a Biological Matrix Used in Abdominal Wall Reconstruction
The general objective of the study is to confirm the medium/long-term safety and clinical performance of the CELLIS membrane used in abdominal wall reconstruction including, but not limited to, ventral hernia repair and stoma…
- Conditions
- Abdominal Wall Defect, Abdominal Wall Injury, Abdominal Hernia
- Trial name
- PMCF_AWR (NCT04580511)
- Testing
- CELLIS (Porcine Acellular Dermal Matrix, PADM)
- Where
- 4 sites in France
- Volunteers
- 92 people
- Sponsor
- Meccellis Biotech
Abdominal Wall Defect, Abdominal Wall Hernia
Abdominal Wall Reconstruction With PVDF Mesh in the Setting of Active Infection
The use of synthetic mesh to repair infected defects of the abdominal wall remains controversial. This study aimed to evaluate the short-term outcomes of using PVDF mesh to treat infected abdominal wall defects in the elective…
- Conditions
- Abdominal Wall Defect, Abdominal Wall Hernia, Abdominal Wall Infection, Abdominal Wall Fistula
- Trial name
- NCT05061264
- Testing
- Abdominal wall reconstruction
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- University of Sao Paulo General Hospital
Abdominal Wall Defect
Vascularized Composite Allotransplantation for Treatment of Abdominal Wall Defects
Abdominal wall transplantation surgery is the transfer of abdominal wall tissues from a deceased human donor to a patient with a large abdominal wall defect.
- Trial name
- NCT02416674
- Testing
- abdominal wall transplantation, Immunosuppressive Agents
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Incisional Hernia
ACute Treatment of Incisional Ventral Hernia
This observational, retrospective study aims to examine surgical outcomes in non-elective surgery for incisional hernia. The main questions it aims to answer are: 30-day morbidity short- and long-term surgical outcomes Data will…
- Trial name
- ACTIVE (NCT05620121)
- Testing
- Surgery for Incisional hernias
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Ospedale San Camillo
Amputation, Traumatic, Amputation;Traumatic;Old
Novel Strategies to Improve Immunomodulation and Non-invasive Clinical Monitoring in VCA
The objective of this study is to develop a feasible and safe regimen for minimization of immune suppression in recipients of vascularized composite allotransplants (VCA) using a daily dose of recombinant IL-2.
- Conditions
- Amputation, Traumatic, Amputation;Traumatic;Old, Face Injury, Face; Deformity
- Trial name
- NCT03241719
- Testing
- IL-2
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Brigham and Women's Hospital
Hernia of Abdominal Wall, Incisional Hernia
"BP as a New Device for Surgery and Solid Cancer and Hematopoietic System Tumors Treatment. Effects of BP Implantation"
Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias in humans, in laparotomic procedures and as a new device…
- Trial name
- DM159 (NCT02328352)
- Testing
- BP selfstanding felt, PP mesh, BP intraperitoneal mesh
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Incisional Hernia, Abdominal Wall Defect
Stepwise for the Treatment of Lateral Incisional Hernias
The best approach for lateral incisional hernia is not known. Posterior component separation (reverse TAR) offers the possibility of using the retromuscular space for medial extension of the challenging preperitoneal plane.
- Conditions
- Incisional Hernia, Abdominal Wall Defect, Abdominal Wall Hernia, Hernia
- Trial name
- NCT05205213
- Testing
- Surgical Technique (lateral retromuscular preperitoneal)
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Henares University Hospital
Hernia, Ventral, Intestinal Fistula
RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction
The purpose of the study is to compare the clinical outcomes of two commonly used, FDA-approved biologic meshes in hernia repair and abdominal wall reconstruction (Strattice and XenMatrix).
- Conditions
- Hernia, Ventral, Intestinal Fistula, Fibromatosis, Abdominal
- Trial name
- NCT02228889
- Testing
- Abdominal wall reconstruction with Strattice, Assess pain intensity at last office visit preoperatively, Assess pain interference at last office visit preoperatively
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Jeffrey Janis
Hernia
TIGR vs Polypropylene (Permanent) Mesh: Randomised Trial
Hypothesis: TIGR mesh as a reconstruction material is a more effective mesh for the repair of the abdominal wall post lipectomy, transverse rectus abdominis myocutaneous (TRAM) / deep inferior epigastric perforator (DIEP) flap.
- Trial name
- NCT01136603
- Testing
- TIGR Mesh
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- National University Hospital, Singapore
Hernia
Feasibility of Permacol Use in Infected Fields
This pilot study is to examine the feasibility of using Permacol Surgical Implant in the repair of abdominal wall defects after removal of infected prosthetic mesh
- Trial name
- NCT00820040
- Testing
- acellular porcine dermal collagen mesh
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Medtronic - MITG
Transplant;Failure,Kidney, Transplant; Failure, Liver
Abdominal Wall Transplant
The purpose of this protocol is to determine the safety and efficacy of abdominal wall transplantation as a treatment for the reconstruction of abdominal wall defects.
- Conditions
- Transplant;Failure,Kidney, Transplant; Failure, Liver, Transplant; Failure, Bowel, Abdominal Wall Defect
- Trial name
- NCT03310905
- Testing
- Abdominal Wall Transplant with another solid organ transplant, Abdominal Wall Transplant alone
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Abdominal Wound Dehiscence, Burst Abdomen
Vacuum-Assisted Closure Versus Graduated Primary Skin Closure for Postoperative Burst Abdomen
Burst abdomen, or complete abdominal wound dehiscence, is a severe postoperative complication characterized by the separation of the musculo-aponeurotic layer of the abdominal wall.
- Conditions
- Abdominal Wound Dehiscence, Burst Abdomen, Surgical Wound Dehiscence
- Trial name
- NCT07797868
- Testing
- Vacuum-Assisted Closure (VAC) Therapy, Graduated Primary Skin Closure
- Volunteers
- 50 people
- Sponsor
- Assiut University