Clinical trials: Abdominoplasty
Characteristics of Subcutaneous Tissue
Histopathology Following CCH Injection
To evaluate the histopathology of subcutaneous tissue isolated after single or multiple Collagenase Clostridium Histolyticum (CCH) injection techniques in adult female participants undergoing abdominoplasty.
- Trial name
- NCT04236635
- Testing
- Collagenase Clostridium Histolyticum Single Injection Technique, Collagenase Clostridium Histolyticum Multiple Injection Technique
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Seroma, Hematoma
Efficacy and Safety of ARTISS for Flap Adherence in Abdominoplasty
The purpose of the study is to compare the safety and efficacy of ARTISS versus standard of care in adhering tissue places and reducing seroma/hematoma formation in subjects undergoing abdominoplasty.
- Trial name
- NCT01112735
- Testing
- FS VH S/D 4 s-apr (= two-component fibrin sealant, double virus inactivated, made from pooled human plasma), Standard of care
- Where
- 6 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Elastosis
PEAK PlasmaBlade™ vs. Traditional Electrosurgery in Abdominoplasty
The objective of this clinical study is to evaluate healing of incisions made with the PEAK PlasmaBlade 4.0 compared to scalpel and traditional electrosurgery (Bovie); to monitor and record key post-operative metrics following…
- Trial name
- PRECISE (NCT00943150)
- Testing
- PEAK PlasmaBlade, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medtronic Surgical Technologies
Scars
Safety and Efficacy of SLI-F06 in Wound Healing and Scar Appearance
Multicenter, double-blind study comparing SLI-F06 to vehicle formulation buffer for the improvement in scar appearance and wound strength in routine surgical excisions, as well as post-operative abdominoplasty scar appearance.
- Trial name
- NCT03880058
- Testing
- SLI-F06, Formulation buffer
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Scarless Laboratories, Inc.
Cicatrix, Scar Prevention
Evaluation of the Safety, Pharmacokinetics, and Preliminary Effect on Scar Formation by RXI-109
The primary purpose of this study is to evaluate the safety and tolerability of a single intradermal administration of RXI-109 at small surgical incisions in the abdominal skin that will later be removed during an elective…
- Trial name
- NCT01640912
- Testing
- RXI-109
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- RXi Pharmaceuticals, Corp.
Hernia, Abdominal, Abdominal Injuries
ENHANCE: A Prospective EvaluatioN of Permacol™ in tHe Repair of Complex AbdomiNal Wall CasEs
The objective of this prospective study is to evaluate short-term, mid-term, and long-term clinical outcomes associated with the use of Permacol™ Biological Implant in the treatment of complex abdominal wall defects
- Trial name
- ENHANCE (NCT01268514)
- Where
- 12 sites in Belgium, Germany and 3 more
- Volunteers
- 115 people
- Sponsor
- Medtronic - MITG
Abdominal Wall Defects
A Retrospective Study Evaluating the Use of Permacol Surgical Implant in the Repair of Abdominal Wall Defects
To evaluate short, mid and long term clinical outcomes associated with the use of Permacol in the treatment of abdominal wall defects.
- Trial name
- NCT01214252
- Testing
- Permacol Surgical Implant
- Where
- United States
- Volunteers
- 343 people
- Sponsor
- Medtronic - MITG
Ventral Hernia, Incisional Hernia
A Prospective Study of Fortiva in Hernia Repair
The goal of this study is to evaluate safety and performance of the Fortiva Tissue Matrix. Participants will complete questionnaires to measure outcomes after hernia surgery for two years.
- Conditions
- Ventral Hernia, Incisional Hernia, Abdominal Wall Reconstruction
- Trial name
- NCT06101979
- Testing
- Fortiva Tissue Matrix
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- RTI Surgical
Abdominoplasty
In-vivo Analysis of a Fractional CO2 Laser System (eMatrixCO2) Intended for Treatment of Soft Tissue
This study will: Evaluate the in vivo effects of treatment with eMatrixCO2 and to determine the dynamics of their development over time following treatment.
- Trial name
- eMatrixCO2 (NCT01026662)
- Testing
- Ablation and skin resurfacing, eMatrixCO2
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Unwanted Abdomen Fat
VelaShape and Contour I V3 for Abdominal Fat Reduction vs. Control
Prospective, 2-arm, clinical study for the evaluation of the VelaShape device and Contour I V3 device for non-invasive fat reduction vs. control.
- Trial name
- NCT02553278
- Testing
- VelaShape device, Contour I V3 device
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Analgesia
A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE
This is a Phase 4, randomized, blinded, active-controlled, multicohort study to evaluate HTX-011 compared with bupivacaine HCl in subjects undergoing abdominoplasty (Cohort 2).
- Trial name
- NCT06109428
- Testing
- HTX-011, Bupivacaine Hydrochloride, Ibuprofen
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Heron Therapeutics
Acute Pain
A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After an Abdominoplasty
The purpose of this study is to evaluate the efficacy and safety of VX-548 doses in treating acute pain after an abdominoplasty.
- Trial name
- NCT05034952
- Testing
- VX-548, HB/APAP
- Where
- 7 sites in United States
- Volunteers
- 303 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Pain, Postoperative, Hernia, Ventral
An Open-label Safety and Pharmacokinetic Study of INL-001 in Adults Following Various Open Soft-Tissue Surgeries
This is a multicenter, Phase 3, open-label, safety, tolerability, and characterization of pharmacokinetics study of the INL 001 (bupivacaine HCl) implant, at 300 mg, in patients following various soft-tissue surgeries: open…
- Conditions
- Pain, Postoperative, Hernia, Ventral, Abdominoplasty, Hysterectomy
- Trial name
- NCT04785638
- Testing
- INL-001 (bupivacaine hydrochloride) implant
- Where
- 8 sites in United States
- Volunteers
- 100 people
- Sponsor
- Innocoll
Disorder of Skin and/or Subcutaneous Tissue of Trunk
Clinical Trial Comparing Standard Wound Closure Techniques Versus TissuGlu® Surgical Adhesive
The purpose of this study is to determine if TissuGlu® Surgical Adhesive is safe and effective alternative to drains(standard of care) for fluid management following abdominoplasty.
- Trial name
- NCT01791504
- Testing
- TissuGlu Surgical Adhesive
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Cohera Medical, Inc.
Acute Pain
A Study of Cebranopadol for the Treatment of Acute Pain After Abdominoplasty
The purpose of this study is to evaluate the efficacy and safety of Cebranopadol for acute pain after a Abdominoplasty.
- Trial name
- ALLEVIATE1 (NCT06545097)
- Testing
- Cebranopadol 400 ug, Cebranopadol 200 ug
- Where
- 4 sites in United States
- Volunteers
- 279 people
- Sponsor
- Tris Pharma, Inc.
Herniorrhaphy, Abdominoplasty
The Management of Closed Surgical Incisions Resulting From Incisional Hernia Repair and/or Functional Panniculectomy Using the Prevena™ Customizable™ Dressing
The goal of this study is to evaluate the impact of Customizable in the management of extensive closed surgical incisions for Subjects undergoing abdominal surgery for incisional hernia repair and/or functional panniculectomy as…
- Trial name
- NCT02302222
- Testing
- Customizable Dressing with ActiV.A.C. Therapy Unit, Standard of Care Dressing
- Where
- 2 sites in United States
- Volunteers
- 71 people
- Sponsor
- KCI USA, Inc
Scar, Surgical Scar
Pilot Study of a Novel 532nm KTP Laser for the Treatment of Fresh Surgical Scars
The purpose of this study is to evaluate the safety and efficacy of the 532nm potassium titanyl phosphate (KTP) laser in comparison with the 595nm pulsed-dye laser (PDL) for the treatment of fresh surgical scars.
- Conditions
- Scar, Surgical Scar, Cicatrix, Cicatrix, Hypertrophic
- Trial name
- NCT01789346
- Testing
- 532nm KTP, 595nm PDL
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cutera Inc.
Characteristics of Subcutaneous Fat
ATX-101 Abdominoplasty
Histopathological study of abdominal fat excised from subjects undergoing abdominoplasty
- Trial name
- ATX-101-08-10 (NCT00835952)
- Testing
- ATX-101
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kythera Biopharmaceuticals
Scar, Incision
A Safety and Efficacy Study to Evaluate AIV001 in Wound Healing Following Surgical Incision
To evaluate the safety, efficacy and pharmacokinetic profile of ascending concentrations of the study medication compared with vehicle in subjects with incisional wounds
- Conditions
- Scar, Incision, Abdominal, Wound (Morphologic Abnormality)
- Trial name
- NCT03639883
- Testing
- AIV001
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AiViva BioPharma, Inc.
Wounds
OxyGenesys Dissolved Oxygen Dressing; Abdominoplasty at Northwestern University
Twelve acute wounds (6 on either side of the umbilicus) will be surgically created in the lower abdominal area. One side of the umbilicus will be randomized to Oxygenesys treatment arm and the other side will be receiving a…
- Trial name
- NCT02591537
- Testing
- OxyGenesys Dissolved Oxygen Dressing
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Halyard Health