Clinical trials: Abdominoplasty
Incisional Hernia Repair, Ventral Hernia Repair
Comparative Evaluation of Preoperative Preparation Methods in Patients With Large Incisional Hernias
Patients with large, complex, or giant incisional hernias often require advanced preoperative optimization to facilitate safe abdominal wall reconstruction and reduce postoperative complications.
- Trial name
- AWR-PREP (NCT07549113)
- Testing
- Botulinum Toxin A (Botox ), Progressive Preoperative Pneumoperitoneum, Combined Preoperative Preparation
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- State Budget Public Health Institution Scientific Research Institute - Ochapovsky Regional Clinical Hospital
Disorder of Abdomen
Plication of the Rectus Abdominis in Two Planes and in One Continuous Suture Plan
Thirty women with similar abdominal deformities, who had had at least one pregnancy, were randomized into three groups to undergo abdominoplasty.
- Trial name
- NCT02674035
- Testing
- Correction of diastasis of the rectus abdominis muscles
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Luiz Jose Muaccad Gama
Acute Pain, Postoperative Pain Control
An Efficacy and Safety Study of LTG-001 Following Abdominoplasty
The goal of this clinical trial is to learn if LTG-001 works to treat post-operative / acute pain after an abdominoplasty procedure. It will also learn more information on the safety of LTG-001.
- Trial name
- NCT07102459
- Testing
- Experimental: LTG-001 High Dose, Experimental: LTG-001 Low Dose, Active Comparator: HB/APAP
- Where
- 5 sites in United States
- Volunteers
- 343 people
- Sponsor
- Latigo Biotherapeutics
Delay in GI Recovery/Postoperative Ileus (POI)
TU-100 for Accelerating GI Recovery After Major Abdominopelvic Surgery (RC & CAWR)
This Phase 2, multicenter, randomized, double-blind, placebo-controlled master protocol study will evaluate the safety and efficacy of TU-100, adjunctive to an Enhanced Recovery After Surgery (ERAS) pathway, for accelerating…
- Trial name
- NCT07765589
- Testing
- TU-100
- Volunteers
- 240 people
- Sponsor
- Tsumura USA
Abdominal Pain
A Comparison of Postoperative Outcomes Provided by a Continuous Preperitoneal Infusion Versus Ultrasound Guided Rectus Sheath Block for Midline Emergency Laparotomy
aim of this study is to compare the postoperative analgesia provided bya continuous preperitoneal infusion versus ultrasound guided rectus sheath block for midline emergency laparotomy. anticoagulated patients
- Trial name
- NCT03228797
- Testing
- an ultrasound guided rectus sheath block, multiholed catheter, an ultrasound guided rectus sheath block &multiholed catheter
- Volunteers
- 60 people
- Sponsor
- Dr Manar Mamdouh Fahmy Elsharkawi
Healthy Volunteers
Safety Study of Acellular Adipose Tissue for Soft Tissue Reconstruction
The purpose of this study is to assess the safety and tolerability of acellular adipose tissue (AAT), intended for the repair of soft tissue defects in humans, in healthy volunteers.
- Trial name
- NCT02817984
- Testing
- Acellular Adipose Tissue (AAT)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Pain
Comparison of Local Anesthetic Infusion Pump Versus DepoFoam Bupivacaine for Pain Management
The purpose of this study is to identify the best pain management for patients undergoing abdominoplasty after massive weight loss or transverse rectus abdominis myocutaneous (TRAM) flap for breast reconstruction.
- Trial name
- NCT02542956
- Testing
- Exparel, Marcaine
- Where
- United States
- Sponsor
- Henry Ford Health System
Abdominoplasty
Histologic Evaluation of Tissue Following Lutronic System Exposure
Enrollment of up to 25 subjects; subjects enrolled may be greater than subjects receiving test spot exposure visits. No pre-treatment medication prior to test spot exposure.
- Trial name
- NCT04207047
- Testing
- Genius, eC02, PicoPlus
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Submental Fat (SMF), Double Chin
RJV001 Study in Adults Receiving Abdominoplasty
In this study, we are testing a new drug against submental fat (SMF), which is characterized with the accumulation of fat under the chin that often appears as a "double chin".
- Trial name
- NCT04821648
- Testing
- RJV001
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rejuven Dermaceutical Co., Ltd.
Abdominal Obesity
A Study to Evaluate Safety, Tolerability of Subcutaneous Injection in Adult Subjects Undergoing Abdominoplasty
Dose-ranging, randomized, double-blind, vehicle-controlled study
- Trial name
- NCT05422378
- Testing
- STP705
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Sirnaomics
Abdominal Skin Redundancy
Laser Fluorescent Imaging of Abdominal Skin During Abdominoplasty
Abdominoplasty is a common cosmetic operation. Some investigators believe that the risk of complications is reduced by limiting the operative dissection. However, this can compromise the quality of the result.
- Trial name
- NCT02196779
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swanson Center
Scar Prevention
Safety and Efficacy Study of Different Dose Levels of EXC 001 to Improve the Appearance of Scars in Subjects Undergoing Elective Abdominoplasty
This study will compare how well EXC 001 works versus placebo in reducing the appearance of scars in subjects undergoing elective abdominoplasty. The study will also evaluate the safety of EXC 001 in healthy adult subjects.
- Trial name
- NCT01038297
- Testing
- EXC 001
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pfizer
Obesity, Hypesthesia
Post-bariatric Abdominoplasty: Skin Sensation Evaluation
The purpose of this study is to quantify the skin sensation of the anterior abdominal wall of the post-bariatric patients submitted to anchor-line abdominoplasty without flap undermining.
- Trial name
- NCT00831610
- Testing
- Bariatric surgery (Roux-en-Y Gastric Bypass) + Post-bariatric abdominoplasty., Roux-en-Y gastric bypass (bariatric surgery) + Post-bariatric abdominoplasty (without flap undermining)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of São Paulo
Abdominoplasty Surgery
Comparison Between Vacuum Drain and Passive Drain In Abdominoplasty
The aim of the present study is to: Compare the subcutaneous collection with Vacuum Drain and Passive Drain insertion at abdominoplasty surgery
- Trial name
- NCT06486298
- Testing
- Vacuum Drain and Passive Drain insertion at abdominoplasty surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Abdominal Wall Defect, Abdominal Wall Hernia
Abdominal Wall Reconstruction With PVDF Mesh in the Setting of Active Infection
The use of synthetic mesh to repair infected defects of the abdominal wall remains controversial. This study aimed to evaluate the short-term outcomes of using PVDF mesh to treat infected abdominal wall defects in the elective…
- Conditions
- Abdominal Wall Defect, Abdominal Wall Hernia, Abdominal Wall Infection, Abdominal Wall Fistula
- Trial name
- NCT05061264
- Testing
- Abdominal wall reconstruction
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- University of Sao Paulo General Hospital
Abdominal Obesity, Postoperative Pain
Transversus Abdominis Plan Block Versus Rectus Sheath Block
The investigator aims to compare the analgesic efficacy of Transversus Abdominis Plan Block and Rectus Sheath Block which are used to prevent intraoperative and postoperative pain and reduce the use of opioid in abdominoplasty…
- Conditions
- Abdominal Obesity, Postoperative Pain, Postoperative Complications
- Trial name
- NCT06897345
- Testing
- transversus abdominis plane block, rectus sheat block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Hernia, Ventral, Intestinal Fistula
RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction
The purpose of the study is to compare the clinical outcomes of two commonly used, FDA-approved biologic meshes in hernia repair and abdominal wall reconstruction (Strattice and XenMatrix).
- Conditions
- Hernia, Ventral, Intestinal Fistula, Fibromatosis, Abdominal
- Trial name
- NCT02228889
- Testing
- Abdominal wall reconstruction with Strattice, Assess pain intensity at last office visit preoperatively, Assess pain interference at last office visit preoperatively
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Jeffrey Janis
Post Operative Pain
Transversus Abdominis Plane Blocks With Abdominoplasty
Comparing morphine consumption and recovery with two different TAP block techniques after abdominoplasty.
- Trial name
- TAPA (NCT01278264)
- Testing
- Ropivacaine 0.25%, 0.5 ml/kg
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Saint-Jean, Bruxelles
Cicatrix, Scar Prevention
Evaluation of the Safety, Pharmacokinetics, and Preliminary Effect on Scar Formation by RXI-109
The primary purpose of this study is to evaluate the safety and tolerability of a single intradermal administration of RXI-109 at small surgical incisions in the abdominal skin that will later be removed during an elective…
- Trial name
- NCT01640912
- Testing
- RXI-109
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- RXi Pharmaceuticals, Corp.
Anemia, Iron-Deficiency, Weight Loss
Iron Supplementation for Acute Anemia After Postbariatric Abdominoplasty
The purpose of this study is to determine whether intravenous or oral iron are effective in the treatment of postoperative anemia and iron deficiency in patients submitted in postbariatric abdominoplasty.
- Trial name
- ISAPA (NCT01857011)
- Testing
- Intravenous Iron sucrose, Oral Iron
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Federal University of São Paulo