Clinical trials: Ablation Techniques
Liver Disease
Randomised Prospective Study of CUSA Versus Radiofrequency Ablation Technique in Liver Resections
The purpose of this study is to determine whether a particular method of operating on the liver is superior to the "gold" standard commonest technique.
- Trial name
- NCT06980571
- Testing
- radiofrequency ablation
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Barts & The London NHS Trust
Atrial Fibrillation, Atrial Tachycardia
AutoMatic disPERsion Tagging Function Preliminary Evaluation
Interventional, prospective, non-randomized, single-center, non-controlled clinical investigation as part of the premarket clinical evaluation of VX1+ medical device, aiming to verify that VX1+ in bidirectional configuration with…
- Conditions
- Atrial Fibrillation, Atrial Tachycardia, Atrial Arrhythmia
- Trial name
- AMPERE (NCT05362656)
- Testing
- VX1+ dispersion mapping
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Volta Medical
Osteoarthritis Knee, Chronic Pain
Comparison of Denervation Techniques for the Treatment of Knee Osteoarthritis: Continuous Ablative Radiofrequency Vs. Chemical Denervation with Absolute Alcohol
This randomized clinical trial compares two minimally invasive treatments for knee osteoarthritis pain that has not responded to conventional therapies.
- Trial name
- NCT06858228
- Testing
- Continuous Ablative Radiofrequency, Chemical Denervation with Absolute Alcohol
- Where
- Brazil
- Volunteers
- 288 people
- Sponsor
- Federal University of São Paulo
Atrial Fibrillation
Esophagus Imaging for Radiofrequency Ablation of Atrial Fibrillation
As the left atrium is in close vicinity to the esophagus, radiofrequency ablation in the left atrium may damage the esophagus and create esophageal perforations and esophageal left atrial fistula.
- Trial name
- NCT00650728
- Testing
- placing gastric tube
- Where
- Switzerland
- Sponsor
- Luzerner Kantonsspital
Atrial Fibrillation
The Physiological Effects of Pacing on Catheter Ablation Procedures to Treat Atrial Fibrillation
This is a two arm randomized, paired prospective study comparing the percentage of time spent above Contact Force (CF), Force Time Integral (FTI) and other lesion parameters in the setting of pacing versus non-pacing.
- Trial name
- PEP AF (NCT02766712)
- Testing
- Pace During 1st Half of Lesion, Pace During 2nd Half of Lesion
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- NYU Langone Health
Pilonidal Sinus
Pilonidal Sinus Disease
The aim of this study is to compare the outcomes of Karydakis technique versus sinus tract ablation procedure using 1470 nm Diode laser for the treatment of pilonidal sinus and provide evidence-based guidance to select the most…
- Trial name
- NCT06508086
- Testing
- laser ablation technique in the treatment of pilonidal sinus, Karydakis technique in the treatment of pilonidal sinus
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Ablation Techniques, RFA, Ablation Treatment
Efficacy and Safety of RFA vs MWA for Treatment of Large Benign Thyroid Nodules, RCT
We conduct a multi-institutional randomized control trial of RFA and MWA for the primary treatment of large, benign nodules. Adult patients >/=18 years of age who have a solitary thyroid nodule ≥20ml in volume who presents to 1)…
- Conditions
- Ablation Techniques, RFA, Ablation Treatment, Benign Thyroid Nodules, Local Anaesthesia
- Trial name
- NCT07804862
- Testing
- Radiofrequency ablation alone, Microwave ablation
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Plantar Fasciopathy, Chronic Pain
One Cause of Heel Pain is Plantar Fasciopathy (PF). In Most Cases, a Heel Spur is Frequently Present Alongside PF. We Aim to Evaluate the Efficacy of Corticosteroid Injection and Radiofrequency Ablation, Along With Tissue Elasticity Assessed by Ultrasound, in Patients With Chronic Pain (≥6 Months).
Heel pain is common among adults. One cause of heel pain is plantar fasciopathy (PF). In most cases, a heel spur, a bony prominence that extends into the plantar fascia, is frequently present alongside PF.
- Conditions
- Plantar Fasciopathy, Chronic Pain, Corticosteroid Injection, Radiofrequency Ablation
- Trial name
- NCT07120204
- Testing
- Corticosteroid Injection, Radiofrequency thermocoagulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- TC Erciyes University
ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION, PFA Ablation and LAAC Procedures
Left Atrial Appendage Closure With Versus Without Pulsed Field Ablation in Atrial Fibrillation Patients With Mild Symptoms and High Stroke Risk
This study is a prospective, multicenter, single-blinded, randomized controlled trial to investigate whether concomitant left atrial appendage closure (LAAC) and pulsed field ablation (PFA) is more effective than LAAC alone in…
- Trial name
- REVERSE-OPTION (NCT07453940)
- Testing
- LAAC plus PFA for persistent AF with high risk of stroke, LAAC for persistent AF with high risk of stroke
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sir Run Run Shaw Hospital
Atrial Fibrillation, Catheter Ablation
Registry Evaluating AF Ablation Techniques
The purpose of this observational registry is to prospectively collect procedure efficiency, safety and acute and long term outcome data from catheter ablation procedures as treatment of paroxysmal atrial fibrillation, using the…
- Trial name
- PRIME-AF (NCT03695484)
- Where
- 3 sites in Belgium, Netherlands and 1 more
- Volunteers
- 212 people
- Sponsor
- Erasmus Medical Center
Atrial Fibrillation
Risk of Asymptomatic Cerebral Embolism During AF Ablation With AI-HPSD Strategy Versus Standard Settings
The purpose of this prospective randomized controlled study is to evaluate the risk of asymptomatic cerebral embolism during catheter ablation of atrial fibrillation (AF) with AI-HPSD strategy versus standard radiofrequency…
- Trial name
- NCT04408716
- Testing
- Ablation Index Guided High-Power Short-Duration Strategy, Standard Radiofrequency Ablation Technique
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Barrett's Esophagus, High-grade Dysplasia in Barrett Esophagus
Eradicating Barrett's Esophagus Using Radiofrequency Ablation or a Novel Hybrid Argon Plasma Coagulation Technique
Lay summary: Barrett's Esophagus (BE) involves a change of the esophagus lining (BE epithelium) which in a small proportion of patients could be the starting point for the development of cancer (esophageal adenocarcinoma).
- Conditions
- Barrett's Esophagus, High-grade Dysplasia in Barrett Esophagus, Low Grade Dysplasia in Barrett Esophagus
- Trial name
- BURN (NCT03621319)
- Testing
- Hybrid argon plasma ablation (HAPC), Radiofrequency ablation (RFA)
- Where
- 13 sites in United States
- Volunteers
- 41 people
- Sponsor
- Erbe Elektromedizin GmbH
Liver Cancer
Feasibility of a Minimally Invasive Image-Guided Surgery System for Hepatic Procedures
This study was designed in two phases: Phase I is designed to confirm that the surgeon is able to perform accurate liver surface registration including standard liver features used as landmarks during a scheduled laparoscopic…
- Trial name
- NCT01286428
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Pathfinder Therapeutics
Vascular Anomalies
Radiofrequency Ablation of Vascular Anomalies
Vascular Anomalies (VA) are areas of disorganized blood vessel tissue that can appear as lumps or bumps under the skin. Sometimes they can cause you discomfort, or you may not like how they look.
- Trial name
- NCT06803667
- Testing
- Radiofrequency ablation alone
- Volunteers
- 15 people
- Sponsor
- Baylor College of Medicine
Obesity, Obesity, Morbid
Biological Sample Repository for Gastrointestinal Disorders
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients…
- Conditions
- Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder
- Trial name
- NCT05874726
- Testing
- Blood Collection, Urine Collection, Tissue Sample Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
Therapy Resistant Hypertension
Randomized Comparison of Ultrasound Versus Radiofrequency Denervation in Patients With Therapy Resistant Hypertension
Prospective, randomized trial to assess the effectiveness of different renal sympathetic denervation methods (radiofrequency main vs. branches + main vs.
- Trial name
- RADIOSOUND (NCT02920034)
- Testing
- Radiofrequency denervation of the main renal arteries, Radiofrequency denervation of renal arteries and branches, Ultrasound denervation of the main renal arteries
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Heart Center Leipzig - University Hospital
Contraceptive Usage
Ablation of Subcutaneous Contraceptive Implants in the Operating Room
The ablation of subcutaneous contraceptive implants is usually performed in consultation under local anesthesia. However, it happens that the implant was placed too deeply or that it migrated too deeply making it impossible to…
- Trial name
- TAICS (NCT05932537)
- Testing
- Preoperative visualization techniques
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Hepatocellular Carcinoma, Radiofrequency Ablation
Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma With No-touch Technique
The aim of this study is to evaluate clinical outcome of RFA for small single nodular HCC using no touch technique with separable clustered electrode (Octopus) in a prospective multicenter manner Participating center: Seoul…
- Trial name
- NCT03375281
- Testing
- RFA
- Where
- 5 sites in South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital
Low Back Pain
Technical Efficacy of a Direction Specific Radiofrequency Device in the Performance of Lumbar Medial Branch Neurotomies
The purpose of this study is to document the effectiveness of the Nimbus Multi-tined Expandable Electrode (MEE) Probe in carrying out the heating and ablation (cutting) of the small medial branch nerves that carry pain…
- Trial name
- NCT02120625
- Testing
- Lumbar MB RFN
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Nimbus Concepts, LLC
Patient Satisfaction, Dehydration
NPO and Patient Satisfaction in the Cath Lab
The purpose of this randomized, control study is to compare liberal vs strict nil per os (NPO) policies on patients undergoing transcatheter aortic valve replacement (TAVR) or arrhythmia ablation.
- Conditions
- Patient Satisfaction, Dehydration, Physiological Effects Secondary to Dehydration
- Trial name
- FAST (NCT04079543)
- Testing
- NPO past midnight, NPO
- Volunteers
- 200 people
- Sponsor
- Stony Brook University