Clinical trials: Ablation Treatment
Varicose Veins of Lower Limb
Ongoing Registry of Treatment of Chronic Venous Diseases
Ongoing registration of patients with varicose veins disease treated by means of conventional surgery, endovenous thermal ablations, sclerotherapy, non-tumescent non-thermal methods
- Trial name
- RRT CVD (NCT03035747)
- Testing
- conventional surgery, endovenous laser ablation, sclerotherapy
- Where
- Russia
- Volunteers
- 5,000 people
- Sponsor
- Medalp Private Surgery Clinic
Prostate Cancer
Sunitinib Malate, Hormone Ablation and Radiation Therapy in Patients With Prostate Cancer
The goal of this clinical research study is to learn the safety of adding 3 different dose-levels of Sutent® (sunitinib malate) to a combination of hormone therapy and radiation in patients with prostate cancer.
- Trial name
- NCT00631527
- Testing
- Leuprolide, Goserelin, Sunitinib Malate
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- M.D. Anderson Cancer Center
Unresectable Hepatocellular Carcinoma
Atezolizumab Plus Bevacizumab Combined With Locoregional Therapies in Unresectable Hepatocellular Carcinoma (ISMIO-001)
This is a retrospective, multicenter, real-world cohort study designed to evaluate the effectiveness and safety of atezolizumab plus bevacizumab (Atezo+Bev) combined with various locoregional therapies (LRTs), including…
- Trial name
- ISMIO001 (NCT07204327)
- Testing
- Atezo+Bev plus Locoregional Therapy
- Where
- China
- Volunteers
- 1,136 people
- Sponsor
- Zhongda Hospital
Low Back Pain
A Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves for theTreatment of Lumbar Facet Syndrome
This study is being done to determine whether cooled radiofrequency ablation (CRFA) on the medial branch nerves of the lumbar facet joint is effective for the treatment of low back pain.
- Trial name
- STU00097239 (NCT02478437)
- Testing
- Conventional radiofrequency ablation (RFA), Cooled Radiofrequency Ablation (CRFA)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Northwestern University
Adenocarcinoma of the Prostate, Stage IV Prostate Cancer
R-(-)-Gossypol and Androgen Ablation Therapy in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer
This phase II trial is studying how well giving gossypol together with androgen ablation therapy works in treating patients with newly diagnosed metastatic prostate cancer.
- Trial name
- NCT00666666
- Testing
- AT-101, Bicalutamide, LHRH agent
- Where
- 4 sites in United States
- Volunteers
- 55 people
- Sponsor
- National Cancer Institute (NCI)
Obesity, Adiposity
HybridAPC for Gastric Mucosal Ablation in Obese Patients.
This study is intended to investigate safety and feasibility of a new weight loss technique called Gastric Mucosal Ablation (GMA) that does not require surgery, but can be achieved using an endoscopic procedure.
- Trial name
- NCT05587491
- Testing
- Hybrid Argonplasma coagulation (HAPC)
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Erbe Elektromedizin GmbH
Prostate Cancer
Study of Focal Ablation of the Prostate With NanoTherm® Therapy System for Intermediate-Risk Prostate Cancer
Stage 2B: NanoTherm ablation of focal prostate cancer in small lesions in Gleason 3+4 disease. The outcome of this ablation is validated by a transperineal biopsy at 4 months after ablation.
- Trial name
- NCT05010759
- Testing
- NanoTherm Ablation
- Where
- 4 sites in United States
- Volunteers
- 3 people
- Sponsor
- MagForce USA
Atrial Fibrillation
Safety and Efficacy Study of The Combined Ablation Procedure To Treat Longstanding Persistent Atrial Fibrillation
This is a multi-center, prospective open label, feasibility study evaluating the safety and efficacy of the combined ablation procedure for the treatment of longstanding persistent atrial fibrillation.
- Trial name
- CAPstopsLSPAF (NCT01103661)
- Testing
- Numeris®-AF Guided Coagulation System with VisiTrax®
- Where
- 4 sites in United States
- Volunteers
- 7 people
- Sponsor
- nContact Surgical Inc.
Ventricular Tachycardia, Ischemic
Early Ablation Therapy for the Treatment of Ischemic Ventricular Tachycardia in Patients With Implantable Cardioverter Defibrillators
The purpose of this study is to determine if early ablation (i.e., ablation of ventricular tachycardia in patients with infrequent VT episodes) is more effective than medical therapy alone for the treatment of ischemic…
- Trial name
- ASPIRE (NCT01557842)
- Testing
- Drug Treatment, Catheter Ablation
- Where
- 23 sites in United States
- Volunteers
- 15 people
- Sponsor
- Biosense Webster, Inc.
Atrial Fibrillation, Pulmonary Vein Isolation
Lesion Characteristics After Pulsed-Field Ablation in Patients With Atrial Fibrillation and a Left Common Ostium
This study aims to investigate the lesion characteristics after pulmonary vein isolation using pulsed-field ablation in patients with atrial fibrillation and a common of the left pulmonary veins.
- Conditions
- Atrial Fibrillation, Pulmonary Vein Isolation, Ablation Therapy
- Trial name
- PFALCO Remap (NCT05812261)
- Testing
- Creating an electro-anatomical map
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
MI Related Malignant Ventricular Arrhythmia
Effect of Radiofrequency Ablation in Patients With Ventricular Arrhythmia Undergoing CABG
Patients with myocardial infarction related potential malignant ventricular arrhythmia have high risk of sudden death. The aim of this clinical trial is evaluating therapeutic efficacy of unipolar or bipolar radiofrequency…
- Trial name
- RACAVA (NCT02991170)
- Testing
- unipolar or bipolar radiofrequency ablation+CABG, CABG
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Beijing Anzhen Hospital
Head and Neck Cancer
Pilot Study of AuroLase(tm) Therapy in Refractory and/or Recurrent Tumors of the Head and Neck
This is an open-label, multicenter, single-dose pilot study of AuroLase(TM) Therapy in the treatment of patients with refractory and/or recurrent tumors of the head and neck.
- Trial name
- NCT00848042
- Testing
- AuroLase Therapy
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Nanospectra Biosciences, Inc.
Lung Cancer
Cryospray Ablation of Surgical Resection Specimens To Determine Safety And Histological Effect In The Lung
The purpose of this study is to evaluate the feasibility and general safety in the human airway as well as assess the safety and depth and area of treatment using liquid nitrogen sprayed through a catheter via flexible fiber…
- Trial name
- CSAir 1 (NCT00747773)
- Testing
- CryoSpray Ablation System
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- CSA Medical, Inc.
Lung Cancer
Percutaneous Thermal Ablation in Lung Tumors
Lung cancer has a high incidence globally, with Egypt having it as the third most common and most lethal cancer, affecting 16.9% of males and 3.8% of females.
- Trial name
- Radiofrequency (NCT06891183)
- Testing
- Percutaneous thermal ablation of lung tumors
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Atrial Fibrillation, Heart Failure
AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study
The purpose of this study is to determine whether early atrioventricular node (AVN) ablation with pacing device therapy will reduce death and hospitalization when compared to the conventional drug therapy in elderly patients with…
- Trial name
- PACIFIC (NCT00589303)
- Testing
- FDA approved rate and rhythm control drugs, AV Node ablation and device implant
- Where
- 6 sites in United States, Canada
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Ventricular Tachycardia, Coronary Artery Disease
Trial Comparing Ablation With Medical Therapy in Patients With Ventricular Tachycardia
This study aims to compare antiarrhythmic drug therapy with catheter ablation using the SmartTOUCH catheter (Biosense Webster Inc.) as treatment for patients with ventricular tachycardia and coronary artery disease
- Trial name
- VeTAMed (NCT01798277)
- Testing
- Catheter Ablation, Medical therapy (sotalol or amiodarone)
- Sponsor
- Newmarket Electrophysiology Research Group Inc
Parkinson Disease
Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)
Evaluate the Safety and Effectiveness of Staged Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD).
- Trial name
- NCT04728295
- Testing
- Exablate 4000
- Where
- 9 sites in United States, Spain and 1 more
- Volunteers
- 50 people
- Sponsor
- InSightec
Varicose Veins
Compression Therapy Following Endothermal Ablation
This study will be looking at the effect of compression therapy in patients having endovenous treatment for truncal incompetence of their varicose veins using either radiofrequency ablation (RFA) or endovenous laser therapy…
- Trial name
- COMETA (NCT02522845)
- Testing
- Class II Compression Stockings (no specific device used)
- Where
- United Kingdom
- Volunteers
- 204 people
- Sponsor
- Imperial College London
Varicose Veins
Mechanochemical Ablation Compared to Cyanoacrylate Adhesive
This study will be comparing the treatment of varicose veins using either mechanochemical ablation (MOCA) or cyanoacrylate adhesive (CAE). Patients will be randomised to receiving either MOCA or CAE.
- Trial name
- NCT03392753
- Testing
- Mechanochemical ablation, Cyanoacrylate adhesive
- Where
- United Kingdom
- Volunteers
- 167 people
- Sponsor
- Imperial College London
Persistent Atrial Fibrillation
Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation
The purpose of this study is to establish the safety and effectiveness of pulsed field ablation as a first-line ablation treatment for subjects with persistent atrial fibrillation as compared to subjects who received an initial…
- Trial name
- AVANT GUARD (NCT06096337)
- Testing
- FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone
- Where
- 61 sites in United States, Australia and 11 more
- Volunteers
- 484 people
- Sponsor
- Boston Scientific Corporation