Clinical trials: Abnormalities, Jaw
Mandibular Deficiency
Vertical Ramus Osteotomy With Iliac Graft Versus Sagittal Split Osteotomy
Patients will be collected from faculty of dentistry bilateral vertical ramus osteotomy (VRO )with iliac graft group (group I):- 10 patients will be treated via VRO and iliac crest or bilateral sagital spilt osteotomy (BSSO)…
- Trial name
- NCT06850194
- Testing
- vertical ramus osteotomy with iliac graft, bilateral sagittal splitting osteotomy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Fayoum University
Congenital Deformity of Face, Post-traumatic Deformity
Patient Satisfaction After Patient-specific Jawline Augmentation
The survey studies patient satisfaction after titanium patient specific jawline augmentation in congenital, post-trauma, deformity and transgender/cosmetic jaw angle/border deficiencies.
- Trial name
- NCT03932734
- Testing
- survey
- Where
- Belgium
- Volunteers
- 26 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cleft Palate
The Role of Antibiotic Prophylaxis in Cleft Palate and Velopharyngeal Insufficiency Repair
Cleft Lip and Palate surgical repair is one of the most common procedures performed by Plastic and Reconstructive Surgeons in the World.
- Trial name
- Cleft Palate (NCT02688634)
- Testing
- Amoxicillin
- Where
- 2 sites in United States
- Sponsor
- University of Florida
Basal Cell Carcinoma, Basal Cell Nevus Syndrome
Vitamin D as a Nutritional Neoadjuvant During Photodynamic Therapy of Basal Cell Carcinoma
The purpose of this study is to study 50 patients with multiple Basal Cell Carcinoma (BCC) who will be receiving Photodynamic Therapy (PDT) as treatment for their tumors.
- Trial name
- NCT03467789
- Testing
- Dietary Vitamin D3 pre-treatment, Photodynamic therapy, Serum Maintenance Vitamin D3
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Case Comprehensive Cancer Center
Maxillary Hypoplasia
Maxillary Segment Tipping During Transpalatal Distraction
The investigator proposes a multi-centre study to investigate tipping of teeth, bringing into consideration the height of the osteotomy line and the height and placement of the transpalatal distractor as possible factors.
- Trial name
- NCT04041388
- Testing
- Conebeam CT
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cleft Palate
Velopharyngeal Insufficiency Evaluation Post Cleft Palate Repair. Furlow With Buccinator Myomucosal Flap Versus Two Flap Palatoplasty
Cleft palate is one of the most common congenital abnormalities of the orofacial region throughout the world. This condition can cause facial deformity, feeding problems, frequent middle ear infections, dental defects, speech…
- Trial name
- NCT06477679
- Testing
- • Furlow with buccinators myomucosal flap, • Two flap palatoplasty as von langenbeck technique
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Dentofacial Deformities, Dentofacial Anomalies [Including Malocclusion] and Other Disorders of Jaw (M26-M27)
Effect of Proximal Segment Positioning on Postoperative Condylar Remodeling in Bimaxillary Orthognathic Surgery
Bimaxillary orthognathic surgery is a surgical procedure that involves simultaneous corrections to both the maxilla (upper jaw) and mandible (lower jaw).
- Trial name
- NCT06897787
- Testing
- manuel positioning group, mandibular basis osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Palatal Expansion Technique, Malocclusion
Comparison Between Two Rates of Activation of Miniscrew-Supported Upper Jaw Expander in Adolescents
Miniscrew-supported maxillary expanders provide advantages over conventional tooth-supported expanders. However, there is no consensus in the literature regarding their activation protocol.
- Conditions
- Palatal Expansion Technique, Malocclusion, Posterior Crossbite, Maxillary Hypoplasia
- Trial name
- NCT04225637
- Testing
- Miniscrew-Supported Maxillary Expander- Slow activation, Miniscrew-Supported Maxillary Expander- Rapid activation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Cleft Palate
Nebulized Bupivacaine Analgesia for Cleft Palate Repair
In this study we introduce a potent local anesthetic; bupivacaine 0.5% in 0.5 mg/kg dose by nebulization as a preemptive analgesia to compare efficacy and safety in children with cleft palate repair.
- Trial name
- NCT04928352
- Testing
- Bupivacaine Hydrochloride, 0.9% saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Nerve Block, Cleft Palate
Maxillary Nerve Blocks in Children - An MRI Study of the Suprazygomatic Approach
Ultrasound-guided suprazygomatic maxillary nerve block (SMNB) will be performed in paediatric patients with or without the aid of ultrasound guidance.
- Conditions
- Nerve Block, Cleft Palate, Analgesia
- Trial name
- NCT05778903
- Testing
- Nerve block
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Cleft Palate
Middle Ear Pressure Disregulation in Cleft Palate Patients
The investigators know that middle-ear disease is very common in infants with cleft palate and causes hearing loss that can last into childhood.
- Trial name
- NCT00423072
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Pittsburgh
Mouth Abnormalities, Cleft Palate
Evaluation of Trigeminal Nerve Blockade
Cleft palate repair requires high doses of opioids for pain control postop. An alternative approach is placement of nerve blocks in the pterygopalatine fossa bilaterally, blocking the maxillary nerve \& covering the entire…
- Conditions
- Mouth Abnormalities, Cleft Palate, Birth Defect
- Trial name
- NCT03632044
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Kallmann Syndrome, Hypogonadotropic Hypogonadism
Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate
The purpose of this study is to explore the genetic basis of reproductive disorders and cleft lip and/or palate.
- Conditions
- Kallmann Syndrome, Hypogonadotropic Hypogonadism, Hypothalamic Amenorrhea, Polycystic Ovarian Syndrome
- Trial name
- NCT01601171
- Where
- Switzerland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Retrognathia, Malocclusion, Angle Class II
Maxillary Patient Specific Implants in Bimaxillary Orthognathic Surgery
Orthognathic surgery is a type of jaw surgery where a surgeon cuts the bones of the upper and lower jaw and places them better. There are two ways they can put the bones in the correct place and keep them in place after the…
- Trial name
- NCT06297109
- Testing
- Patient-specific implants, Conventional mini-plates
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Jaw Deformity
Evaluation of "Tent-Pole" Grafting Technique for Reconstruction of Mandibular Ridge Vertical Defects
The aim of this study is to evaluate clinically and radio-graphically the efficiency of "Tent- Pole "grafting technique for reconstruction of anterior or posterior mandibular ridge defects using synthetic bone graft and Platelet…
- Trial name
- NCT04192851
- Testing
- Tent Pole Technique
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Nourhan M.Aly
Orthognathic Surgery, Malocclusions
Evaluation of Emotional Responses Using the I-Motions System and Self-assessment Questionnaires, and Assessment of Postoperative Anatomical and Structural Units (TMJ and Masticatory Muscles) in Orthognathic Surgery Patients
Orthognathic surgery is a surgical procedure involving one or both jaws to correct skeletal discrepancies, restore proper occlusion, and improve facial aesthetics.
- Conditions
- Orthognathic Surgery, Malocclusions, Jaw Abnormalities, Dentofacial Deformities
- Trial name
- NCT07477873
- Testing
- Observational Assessment
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Pierre Robin Sequence
Usefulness of Cephalometry in the Second and Third Trimester of Pregnancy in the Diagnosis of Fetal Microretrognathia
Congenital retrognathia, with or without Pierre Robin Sequence (PRS), is a rare anomaly which can be associated with chromosomal abnormalities. Respiratory and feeding consequences can be present at birth.
- Trial name
- NCT04422067
- Testing
- Fetal cephalometry
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Montpellier
Cleft Palate
Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair
The primary objective of this study is to evaluate the efficacy of administering intravenous dexmedetomidine as a single preemptive dose to placebo in reducing the total 24 hour dose of opioids as measured on a weight adjusted…
- Trial name
- NCT02915042
- Testing
- Dexmedetomidine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Cleft Palate, Trauma
Cell Therapy for Craniofacial Bone Defects
The purpose of this research is to determine if a patient's own bone marrow tissue can help regenerate bone in the area of the jaw where an implant will be placed. The name of the process is called Bone Repair Cell (BRC) Therapy.
- Trial name
- NCT01616953
- Testing
- Ixmyelocel-T, Autogenous Bone Grafting
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Sleep Apnea Syndromes in Children, Functional Orthodontic Treatment
Evaluation of Functional Orthodontic Treatment on Sleep Quality
Functional appliances are used in the treatment of Class II anomalies caused by mandibular rethrognathia. Herbst which is a fixed and rigid functional appliance and TWB which is removable appliance can be successful in the…
- Conditions
- Sleep Apnea Syndromes in Children, Functional Orthodontic Treatment, Mandibular Retrognathia, Upper Airway
- Trial name
- NCT06660771
- Testing
- Functional orthodontic treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Gökçenur Gökçe Kara