Clinical trials: Abortion, Induced
Abortion in First Trimester
Manual Versus Electric Vacuum Aspiration for Pregnancy Termination Between 10-14 Weeks
The study titled, Manual Versus Electric Vacuum Aspiration for Pregnancy Termination Between 10-14 weeks: A Randomized Trial, is a randomized trial to compare procedure times for manual and electric vacuum aspiration for surgical…
- Trial name
- NCT03079622
- Testing
- Electric Vacuum Aspiration, Manual Vacuum Aspiration
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Washington University School of Medicine
Pregnancy
Feasibility of Medical Abortion by Telemedicine in Mexico
This study is designed to obtain preliminary data on the safety, acceptability, and feasibility of direct-to-consumer telemedicine abortion in Mexico.
- Trial name
- NCT03931460
- Testing
- Medical Abortion
- Where
- 5 sites in Mexico
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion in First Trimester, Abortion, Second Trimester
Second-trimester TOP : a Retrospective Study Comparing Complications at 12-14 vs 14-16 Weeks of Gestation
In France, the recently adopted law relating to the legal time limit for access to voluntary interruption of pregnancy has set a threshold of the term at which it can be performed up to 16 weeks of gestation.
- Trial name
- NCT05469594
- Volunteers
- 122 people
- Sponsor
- Central Hospital, Nancy, France
Missed Abortion
Oxytocin Effectiveness in First Trimester Dilatation and Curettage
The aim of this study is to investigate the impact of oxytocin on perioperative blood loss during the D\&C procedure, as well as to assess early and late complications associated with it's use.
- Trial name
- NCT06469203
- Testing
- Oxytocin, Sodium Chloride 0.9% Inj
- Volunteers
- 160 people
- Sponsor
- Assuta Ashdod Hospital
Medical Abortion
De-Medicalizing Mifepristone Medical Abortion
This study will investigate the possibility that medical abortion using mifepristone and misoprostol - a safe, proven therapy for terminating early first trimester pregnancy - can be administered in a manner that is simpler and…
- Trial name
- NCT00120224
- Where
- 3 sites in United States
- Volunteers
- 4,410 people
- Sponsor
- Gynuity Health Projects
Pain
Hydrocodone For Pain Control in First Trimester Surgical Abortion
The purpose of this study is to determine whether preoperatively administered hydrocodone/acetaminophen (HC/APAP) reduces pain during a first trimester surgical abortion.
- Trial name
- NCT01330459
- Testing
- Hydrocodone/acetaminophen, Ibuprofen, Lorazepam
- Where
- 2 sites in United States
- Volunteers
- 121 people
- Sponsor
- Elizabeth Micks
Missed Miscarriage
Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed Miscarriage
Miscarriage is the most common complication of pregnancy. As many as 15-25% of pregnancies end in miscarriage, and the number of miscarriages in England is estimated to be approximately 125,000 per year.
- Trial name
- MifeMiso (NCT03065660)
- Testing
- Mifepristone, Oral, 200 Mg
- Where
- 28 sites in United Kingdom
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Abortion Early, Abortion in First Trimester
Delivery of Audiovisual Information on Early Medical Abortion
The majority of abortions in the United Kingdom (UK) are performed before 9 weeks (63 days) gestation using a method known as Early Medical Abortion (EMA).
- Trial name
- EMAVID (NCT03417362)
- Testing
- Animation
- Where
- 3 sites in France, Sweden and 1 more
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Pregnancy, Abdominal, Termination of Pregnancy
TENS for Suction Evacuation for Termination of 1st Trimester Pregnancies
To study the effectiveness of the pain relief method of transcutaneous electrical nerve stimulation (TENS) for women who will undergo suction evacuation under conscious sedation for first trimester termination of pregnancy.
- Conditions
- Pregnancy, Abdominal, Termination of Pregnancy, Pain, Nerve
- Trial name
- NCT03494842
- Testing
- Transcutaneous nerve stimulation (TENS)
- Where
- Hong Kong
- Volunteers
- 170 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Abortion
Trial of Immediate Versus Delayed Initiation of Transdermal Hormonal Contraception After Therapeutic Abortion
This is a randomized, controlled trial investigating whether immediate versus standard, "Sunday Start", initiation of transdermal hormonal contraception (the patch) in post-abortion subjects can improve compliance and the…
- Trial name
- NCT00235547
- Testing
- timing of initiation of transdermal patch after an abortion
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Early Pregnancy, Early Pregnancy Loss
EARLY-PREG: A Preconception Cohort Study Based on Counterfactuals to Study Maternal-Embryonic Molecular Interactions
EARLY-PREG is an open-cohort clinical study with a preconception, longitudinal, bidirectional and counterfactual design. The aim of this cohort is to investigate the proteomic signatures of maternal-embryonic communication by…
- Conditions
- Early Pregnancy, Early Pregnancy Loss, Childbirth, Healthy
- Trial name
- EARLY-PREG (NCT07358026)
- Testing
- EMBRYO EXPOSURE
- Where
- Chile
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- MELISA Institute Genomics & Proteomics Research SpA
Polycystic Ovary Syndrome, Miscarriage
The Effects of Metformin on Pregnancy and Miscarriage Rates in Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine whether metformin may improve pregnancy rates, and decrease miscarriage rates and complications of pregnancy, such as toxemia and gestational diabetes, in women with polycystic ovary…
- Conditions
- Polycystic Ovary Syndrome, Miscarriage, Infertility, Toxemia
- Trial name
- NCT00994812
- Testing
- metformin
- Where
- 5 sites in Finland
- Volunteers
- 326 people
- Sponsor
- University of Oulu
Cervical Insufficiency
Relation of the Area of Cerclage With Preterm Birth
This study is planned prospectively in pregnancies who applied to Etlik Zübeyde Hanım Women's Health Care, Training and Research Hospital which is a teritiary hospital with 15.000 births anually, between January 2022 and January…
- Trial name
- NCT05220839
- Testing
- Type of cerclage procedure Mc Donald
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Threatened Abortion
Pregnancy Outcome in Woman With Threatened Abortion
The study aims to quantify the relations between first \& second trimester bleeding and maternal \& neonatal morbidity. Additionally, the study will help in assessing the risk for abortions in women with threatened abortions and…
- Trial name
- POTA (NCT02686112)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Missed Abortion
Comparison of Efficacy and Safety of Oral Versus Vaginal Misoprostol in Missed Abortion in First Trimester of Pregnancy
Incomplete abortion has an eminent clinical diagnosis and is characterized by transvaginal bleeding associated with an open uterine cervix upon physical examination when the products of conception have not been wholly discharged.
- Trial name
- NCT07526064
- Testing
- Oral misoprostol, Misoprostol (given vaginally)
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Hamna Khaliq
Pregnancy
Better Contraceptive Choices: Immediate or Delayed Insertion of IUC After Second Trimester Abortion
Hypothesis Intrauterine contraception placed immediately after a second trimester abortion will result in fewer pregnancies than current standard practice of intended placement at 4 weeks post-abortion.
- Trial name
- NCT00877344
- Testing
- Immediate insertion, Interval insertion
- Where
- 3 sites in Canada
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Abortion, Induced, Abortion, Incomplete
Developing and Testing Interventions to Address Conscientious Objection to Abortion Care in Mexico and South Africa
The primary purpose of this research is to develop strategies and interventions to mitigate the impact of conscientious objection on women's access to safe abortion care in Mexico and South Africa using a user-centered design…
- Trial name
- NCT04290832
- Testing
- CO Intervention
- Where
- 2 sites in Mexico, South Africa
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Ipas
Incomplete Abortion
Treatment of Incomplete Abortion With 600 Mcg Oral Misoprostol Compared to Standard Surgical Treatment
This study aims to compare the efficacy, side effects profile and acceptability of a single dose of 600mcg misoprostol taken orally compared to standard surgical treatment as per local protocols for the treatment of incomplete…
- Trial name
- NCT00674232
- Testing
- 600 mcg misoprostol, Surgical treatment
- Where
- 3 sites in Ecuador, Venezuela
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Threatened Abortion, Progesterone Resistance
Progesterone Supplementation in Threatened Abortion
To decide whether progesterone supplementation in threatened abortion is a sound practice.
- Trial name
- Prothreat (NCT03930212)
- Testing
- Progesterone
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Tanta University
Cervical Incompetence
Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage
This study aims to compare the effect of chloroprocaine vs. bupivacaine on duration of motor block and duration until meeting discharge criteria in patients undergoing cervical cerclage.
- Trial name
- NCT03305575
- Testing
- Chloroprocaine, Bupivacaine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Tufts Medical Center