Clinical trials: Abortion, Recurrent
Cervical Insufficiency, Preterm Birth
Optimal Timing of Routine Cervical Length Measurements During Anatomy Survey
The goal of this clinical trial is to determine the optimal timing for measuring cervical length (CL) during fetal anatomy surveys in pregnant individuals.
- Conditions
- Cervical Insufficiency, Preterm Birth, Cervical Length Measurement
- Trial name
- NCT06822647
- Testing
- Cervical Length Measurement at the Beginning of the Anatomy Survey, Cervical Length Measurement at the End of the Anatomy Survey
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Henry Ford Health System
vitD3 Level in Cases of Recuurent Pregnancy Loss
Assesment of Vit D3 Level in Cases of Unexplaind Pregnancy Loss in Assiut
Assesment of Vit D3 leve in cases of unexplained recurrent pregnancy loss in assiut
- Trial name
- vitDinRPL (NCT03327766)
- Testing
- 4-Measurment of serum 25(OH)D3 using Vidas by ELFA meathod.
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Habitual Abortion
Low Molecular Weight Heparin and/or Aspirin in Prevention of Habitual Abortion
1 % of all pregnancies end in habitual/recurrent abortion. In about half of women with habitual abortions (HAB) hereditary or acquired (antiphospholipid antibodies) thrombophilia are observed.
- Trial name
- HABENOX (NCT00959621)
- Testing
- Aspirin, Klexane, Klexane and ASA
- Where
- Finland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Recurrent Abortion
Low-molecular-weight Heparin (LMWH) Versus Unfractionated Heparin (UFH) in Pregnant Women With Recurrent Abortion Secondary to Antiphospholipid Syndrome
The aim of this study is to compare the efficacy and safety of Low molecular weight heparin (LMWH) plus low dose aspirin (LDA) with unfractionated heparin(UFH) plus LDA in women with recurrent pregnancy loss associated with…
- Trial name
- NCT01051778
- Testing
- enoxaparin 40mg plus low dose aspirin, Heparin calcium5,000 U twice daily plus low dose aspirin
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Recurrent Pregnancy Losses
The Role of Uterine NK Cells and T Cell Cytokines in Recurrent Miscarriage
The aim of the study is to evaluate the role of uterine natural killer cell(uNK)in recurrent pregnancy losses and the correlation between the numbers of it and embryo toxicity by measuring the level of the Th2 cytokines in normal…
- Trial name
- NCT01688284
- Testing
- office hysteroscopy
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Recurrent Abortion
Sildenafil Citrate and Recurrent Abortion
Two groups of unexplained recurrent spontaneous abortion, each included 65 participants. scheduled randomly into; the study group received Sildenafil Citrate and Placebo group.
- Trial name
- NCT03475160
- Testing
- Sildenafil Citrate vaginal suppositories, Uterine artery Doppler before treatment, Uterine artery Doppler after treatment
- Volunteers
- 130 people
- Sponsor
- Benha University
Recurrent Miscarriage
Distinct Alterations in Gut Microbiota Composition Among Women of Reproductive Age With Elevated Homocysteine Levels.
The goal of this observational study is to test the alterations of gut microbiota composition among women of reproductive age with elevated homocysteine levels.
- Trial name
- NCT06001060
- Where
- China
- Volunteers
- 38 people
- Sponsor
- First People's Hospital of Hangzhou
Preterm Labor, Cervical Incompetence
Cervical Cerclage for Singleton Pregnant on Vaginal Progesterone With Progressive Cervical Length Shortening
The aim of this study is to Determine whether cerclage with vaginal progesterone will: 1. Reduce the overall spontaneous preterm birth rate. 2. Prolong pregnancy latency. 3. Improve neonatal outcome.
- Trial name
- NCT03837288
- Testing
- Cerclage
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Recurrent Pregnancy Loss, Anxiety
Cardiac Autonomic and Anxiety Regulation Via Closed-loop nEurofeedback in Recurrent Pregnancy Loss
The goal of this clinical trial is to learn whether right dorsolateral prefrontal cortex (right DLPFC)-targeted fNIRS-BCI online closed-loop neurofeedback, delivered with slow-wave acoustic cueing, can reduce anxiety symptoms and…
- Trial name
- CARE-RPL (NCT07325370)
- Testing
- Right DLPFC fNIRS-BCI closed-loop neurofeedback (real feedback)
- Where
- 2 sites in China
- Volunteers
- 62 people
- Sponsor
- Shenyang Medical College
Recurrent Miscarriage
Intralipid Related Effect on NKcells in Patients With Unexplained Recurrent Spontaneous Abortion
Evaluating the effect of intralipid on the natural killer cells
- Trial name
- NCT03132779
- Testing
- Intralipid
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ahmed Mohamed Bahaa Eldin Ahmed
Hyperinsulinemia, Miscarriages
Maternal Lifestyle and Neonatal Hypoglycemia
tPA has a pivotal role in placentation, mediationg activation of growth factors, such as vascular endothelial growth factor and brain-derived neurotrophic factor, degradation of extracellular matrix and basement membrane…
- Conditions
- Hyperinsulinemia, Miscarriages, Pregnancy, Sedentary Lifestyle
- Trial name
- NCT01409382
- Testing
- Daily brisk walking plus a carbohydrate-restricted diet
- Where
- Brazil
- Volunteers
- 480 people
- Sponsor
- Hospital dos Servidores do Estado do Rio de Janeiro
Recurrent Miscarriage
Expression of EPK in Recurrent Miscarriage
The present study is based on hypotheses that some as yet unknown genetic factors may result in recurrent miscarriage (RM). Consequently, the main aim of this study was to gain new information about the underlying genetic causes…
- Trial name
- EPK-RM (NCT02694367)
- Testing
- Investigate the MAP kinase signaling pathways through ERK and p-ERK proteins
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Assiut University
Recurrent Pregnancy Loss, Anxiety Disorders
Right Prefrontal Autonomic Mapping in Recurrent Pregnancy Loss With Comorbid Anxiety
Recurrent pregnancy loss is often accompanied by substantial anxiety and may also be associated with autonomic imbalance and increased long-term cardiovascular vulnerability.
- Trial name
- NCT06968026
- Testing
- repetitive transcranial magnetic stimulation(rTMS)
- Where
- 4 sites in China
- Volunteers
- 55 people
- Sponsor
- Shenyang Jinghua Hospital
Recurrent Spontaneous Abortion
Prospective Study of BMD and Ca-P Metabolism in RSA Patients: LMWH Use Versus Control
The goal of this prospective observational study is to learn about the effect of low molecular weight heparin (LMWH) application on bone mineral density (BMD) and on calcium-phosphorus metabolism in patients with recurrent…
- Trial name
- NCT05878574
- Testing
- Low molecular weight heparin
- Where
- China
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Aimin Zhao
Recurrent Pregnancy Loss, Infertility, Female
Effects of PGS2.0 in Patients With Unexplained RPL
50%-60% of the known causes of recurrent pregnancy loss(RPL) are associated with embryonic aneuploidy, such that preimplantation genetic screening (PGS) on embryos acquired by assisted reproductive treatment should improve the…
- Trial name
- NCT03214185
- Testing
- IVF/ICSI, PGS 2.0, Conventional embryo morphology evaluation
- Where
- China
- Volunteers
- 710 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Recurrent Pregnancy Loss, Recurrent Implantation Failure
Use of Metabolomics for the Identification of Endometrial Biomarkers for IRPL and RIF After in Vitro Fertilization
It is a case-control study composed of 3 groups : 2 cases groups (RIF and IRPL) already composed as part of a pre-existing research project and 1 control group including patients undergoing ART for male factor infertility.
- Trial name
- ENDOMETAB (NCT03690830)
- Testing
- metabolomics analysis
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers