Clinical trials: Abortion, Spontaneous
Recurrent Miscarriage
Genetic Abnormalities and Oxidative Stress in Sperm as Cause of Recurrent Miscarriage.
In recurrent miscarriage, the male factor has been poorly evaluated. In fact, in the vast majority of clinical protocols of recurrent miscarriage, the sperm is not considered or assessed.
- Trial name
- NCT00447395
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Missed Abortion
Termination Of Anembryonic Pregnancy
Anembryonic pregnancy is a leading cause of early miscarriage. The American Pregnancy Association estimates that blighted ovum causes approximately 50 percent of all first-trimester miscarriages.
- Trial name
- NCT02573051
- Testing
- Misoprostol, Isosorbide mononitrate
- Where
- Egypt
- Sponsor
- Assiut University
Abortion, Spontaneous, Miscarriage, Recurrent
The Role of Hydrosalpinx in Recurrent Miscarriage
Miscarriage affects one in five pregnancies and little progress has been made in understanding and treating this distressing condition. C. trachomatis is the most common sexually transmitted infection in the UK. C.
- Conditions
- Abortion, Spontaneous, Miscarriage, Recurrent, Hydrosalpinx
- Trial name
- NCT03703401
- Testing
- Hysterosalpingo-contrast-sonogram
- Where
- United Kingdom
- Volunteers
- 137 people
- Sponsor
- University of Birmingham
Miscarriage, Preterm Birth
Progesterone for the Prevention of Miscarriage and Preterm Birth in Women With First Trimester Bleeding: PREEMPT Trial
Miscarriages and preterm births are common and serious events affecting women, families, and healthcare systems on many levels. One of the risk factors for miscarriage and preterm birth is bleeding in the first trimester of…
- Trial name
- NCT02145767
- Testing
- Progesterone
- Where
- 7 sites in Canada
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Infertility and Miscarriage
Natural Procreative Technology Evaluation and Surveillance of Treatment for Infertility and Miscarriage
This study involves research, and the purpose of this study is to evaluate live birth rates among couples who are treated by Natural procreative technology, (NPT) for infertility and miscarriage.
- Trial name
- Fertility (NCT02925390)
- Volunteers
- 46 people
- Sponsor
- St. Louis University
Spontaneous Abortion
Comprehensive Assessment of Risks for Miscarriage.
This study aims to determine the role of serum biomarkers and placental bloodflow in the comprehensive evaluation of the risk for spontaneous abortion
- Trial name
- MIS-CARE (NCT04456660)
- Testing
- Markers of ultrasound, Immunologic factors, Serum factors
- Where
- Bulgaria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Orthogyn Medical Center, Bulgaria
Birth Defects, Miscarriages
Pesticides--Health Fertility and Reproductive Risk
This project is designed to establish whether pesticides or other environmental agents have a role in the excess birth defects identified in the Red River Valley of Minnesota.
- Conditions
- Birth Defects, Miscarriages, Cancer
- Trial name
- NCT00015561
- Where
- United States
- Volunteers
- 1,803 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Pregnancy of Unknown Location, Ectopic Pregnancy
Assessment of Biomarkers in Pregnancy on Unknown Location and Ectopic Pregnancy
To further develop the patient care pathway for women classified with a pregnancy of unknown location (PUL) and ectopic pregnancy (EP).
- Conditions
- Pregnancy of Unknown Location, Ectopic Pregnancy, Early Pregnancy, Early Pregnancy Loss
- Trial name
- ABPEP (NCT04738370)
- Testing
- Sample collection
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Birth Defect, Spontaneous Abortions
Nplate® Pregnancy Exposure Registry
US study to estimate the prevalence at birth of major birth defects (ie, those that cause significant functional or cosmetic impairment, require surgery, or are life-limiting) in children born to mothers who have received Nplate®…
- Conditions
- Birth Defect, Spontaneous Abortions, Low Birth Weight
- Trial name
- NPER (NCT02090088)
- Testing
- Not applicable- observational study
- Volunteers
- 4 people
- Sponsor
- Amgen
Spontaneous Abortion, Fetal Death
Environmental Factors and Embryonic Development Project
The Environmental Factors and Embryonic Development Project was set up to investigate environmental exposures and behavioral factors responsible for embryonic dysplasia and gestational complications in pregnant women.
- Conditions
- Spontaneous Abortion, Fetal Death, Stillbirth, Birth Defects
- Trial name
- EFED (NCT04182503)
- Testing
- No intervention
- Where
- 19 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Congenital Uterine Anomalies
Prevalence of Congenital Uterine Malformations
Aims: We plan to investigate how common uterine malformations are in high-risk women (with history of miscarriage or preterm delivery), by analysing different characteristics in these groups.
- Trial name
- PUMA (NCT01487616)
- Where
- United Kingdom
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Abortion, Induced, Labor Stage, Third/Drug Effects
Oxytocin Infusion vs. Spontaneous Follow-up for Third-stage of Labor After Second-trimester Abortion
This study compares oxytocin infusion to spontaneous follow-up for third-stage of labor at induced mid-trimester abortions. Patients will be randomized to oxytocin infusion or observation with no pharmacologic intervention.
- Conditions
- Abortion, Induced, Labor Stage, Third/Drug Effects, Pregnancy Trimester, Second, Oxytocin/Administration & Dosage
- Trial name
- NCT02485444
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ataturk University
Abortion, Spontaneous, Abortion, Induced
Treatment of Late Abortion: Evacuatio Uteri or Conservative Treatment
A randomize trial: expectation or evacuatio uteri for the treatment after late abortion
- Trial name
- NCT00256009
- Testing
- Cytotec
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Vitamin D Deficiency, Recurrent Miscarriage
The Cohort Study of the Correlation Between Serum 25(OH)D Level and Pregnancy Outcome
The objective of this single-center prospective observational study is to clarify the trend of maternal serum 25(OH)D levels before pregnancy and during pregnancy, and to explore the correlation between serum 25(OH)D levels and…
- Conditions
- Vitamin D Deficiency, Recurrent Miscarriage, Pregnancy Related
- Trial name
- NCT05824897
- Testing
- Serum levels of vitamin D
- Where
- China
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Aimin Zhao
Spontaneous Abortion, Missed Abortion
Dilation and Curettage Versus Operative Hysteroscopy for Missed Abortion
Randomizedtrial comparing success and complication rates of operative hysteroscopy versus traditional dilation and curettage (D\&C) in the management of first trimester missed abortion.
- Conditions
- Spontaneous Abortion, Missed Abortion, Intrauterine Adhesion, Retained Products of Conception
- Trial name
- NCT04705324
- Testing
- Operative Hysteroscopy, D&C, Operative Hysteroscopy - safety and feasibility
- Where
- Israel
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Missed Abortion
Sublingual Versus Vaginal Misoprostol In Medical Treatment of First Trimestric Missed Miscarriage
The aim of this work is to compare the effectiveness of vaginal versus sub-lingual misoprostol for medical treatment of first trimester missed miscarriage.
- Trial name
- NCT02686840
- Testing
- sublingual misoprostol, vaginal misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Abortion, Missed
Amniotomy for Second-trimester Pregnancy Termination
The termination of abortion is an important issue that has many controversies. The most common time of serious abortion-related complications is the second trimester.
- Trial name
- NCT04906278
- Testing
- Foley catheter balloon, Amniotomy, Oxytocin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Preterm Birth, Cervical Insufficiency
Nordic Randomized Trial on Laparoscopic Versus Vaginal Cerclage
Every year 15 million babies are born prematurely, which can lead to death or life-long disabilities. It is often caused by a dysfunction of the uterine cervix, which constitutes the narrow channel between the vagina and womb.
- Trial name
- NORACT (NCT06122506)
- Testing
- Laparoscopic cerclage, Vaginal cerclage
- Where
- 2 sites in Denmark
- Volunteers
- 188 people
- Sponsor
- University of Aarhus
High Risk Pregnancy, Incompetent Cervix
Amniotic Fluid Sludge in Cerclage Patients as an Indicator for Increased Risk of Preterm Delivery and Neonatal Outcome.
Amniotic Fluid "Sludge" Does Not Increase Risk of Preterm Delivery in Cerclage Patients.
- Conditions
- High Risk Pregnancy, Incompetent Cervix, Cerclage, Amniotic Fluid Sludge
- Trial name
- NCT00722085
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Center For Maternal Fetal Medicine
Acupuncture, Recurrent Spontaneous Abortion
The Effects of Acupuncture on the Natural Pregnancy in Patients With Recurrent Abortion
Recurrent spontaneous abortion (RSA) is a common pregnancy complication in women of reproductive age and the cause of RSA remains largely unclear. Acupuncture is widely used in clinical practice to treat infertility and abortion.
- Conditions
- Acupuncture, Recurrent Spontaneous Abortion, Ultrasound Therapy, Coagulation
- Trial name
- NCT05998421
- Testing
- acupuncture, routine aspirin and heparin treatment
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Jianmei Xia