Clinical trials: Abortion; Induced
Neutrophil Extracellular Traps; Antiphospholipid Antibody-induced Pregnancy Loss
Neutrophil Extracellular Traps Mediate Antiphospholipid Antibody-induced Pregnancy Loss
1. Establish a multi-platform detection system for neutrophil extracellular traps in blood and tissues, and evaluate the detection performance; 2.
- Trial name
- NCT03735108
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai First Maternity and Infant Hospital
Abortion, Induced, Labor Stage, Third/Drug Effects
Oxytocin Infusion vs. Spontaneous Follow-up for Third-stage of Labor After Second-trimester Abortion
This study compares oxytocin infusion to spontaneous follow-up for third-stage of labor at induced mid-trimester abortions. Patients will be randomized to oxytocin infusion or observation with no pharmacologic intervention.
- Conditions
- Abortion, Induced, Labor Stage, Third/Drug Effects, Pregnancy Trimester, Second, Oxytocin/Administration & Dosage
- Trial name
- NCT02485444
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ataturk University
Undifferentiated Connective Tissue Disease, Recurrent Pregnancy Loss
Immunosuppressant Regimens for Living Fetuses Study
Undifferentiated connective tissue diseases (UCTD) are known to increase the risk of pregnancy morbidities, including recurrent pregnancy loss.
- Trial name
- NCT03671174
- Testing
- Prednisone, Hydroxychloroquine, Aspirin
- Where
- China
- Volunteers
- 420 people
- Sponsor
- RenJi Hospital
Acupuncture, Recurrent Spontaneous Abortion
The Effects of Acupuncture on the Natural Pregnancy in Patients With Recurrent Abortion
Recurrent spontaneous abortion (RSA) is a common pregnancy complication in women of reproductive age and the cause of RSA remains largely unclear. Acupuncture is widely used in clinical practice to treat infertility and abortion.
- Conditions
- Acupuncture, Recurrent Spontaneous Abortion, Ultrasound Therapy, Coagulation
- Trial name
- NCT05998421
- Testing
- acupuncture, routine aspirin and heparin treatment
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Jianmei Xia
Medical Abortion
Medical Abortion at Gestational Age of 8 to ≤9 Weeks Versus >9 to ≤12 Weeks
The purpose of this study is to assess the effectiveness, safety, and acceptability of home-administered medical abortion at gestational age of 8 to ≤9 weeks versus >9 to ≤12 weeks among a cohort of women in Mexico City.
- Trial name
- NCT02745093
- Testing
- Mifepristone, Misoprostol
- Where
- 3 sites in Mexico
- Volunteers
- 648 people
- Sponsor
- Ibis Reproductive Health
Abortion in First Trimester
Pharmacist Provision of Medication Abortion
This will be a pilot study among two pharmacists providing start to finish medication abortions to 10 patients utilizing a previously created toolkit.
- Trial name
- NCT04956731
- Testing
- Pharmacist Provision of Medication Abortion
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Abortion, Induced
Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks
A common practice for preparation for surgical abortion after 19 weeks gestation is the placement of multiple sets of osmostic dilators 1-2 days prior to the procedure.
- Trial name
- NCT01615731
- Testing
- Mifepristone, Hygroscopic cervical dilators, Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Circulating Cell Free Fetal DNA, Intrauterine Fetal Demise
The Use of Cell Free Fetal DNA in the Maternal Blood in the Evaluation of Intrauterine Fetal Demise and Miscarriage
Women presenting to Washington Hospital Center with fetal loss would be offered participation in the study. The objective is to determine if ccffDNA obtained from maternal blood is present in the setting of missed abortion or…
- Conditions
- Circulating Cell Free Fetal DNA, Intrauterine Fetal Demise, Miscarriage
- Trial name
- NCT01916928
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Abortion, Missed
Use of Fetoscopy in Missed Abortion
The purpose of this study is to evaluate the use of hysteroscopic embryoscopy or fetoscopy as a powerful diagnostic tool to provide better counseling for couples having experienced pregnancy loss.
- Trial name
- NCT03799081
- Testing
- Fetoscopy
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hillel Yaffe Medical Center
Miscarriage, Preterm Birth
Progesterone for the Prevention of Miscarriage and Preterm Birth in Women With First Trimester Bleeding: PREEMPT Trial
Miscarriages and preterm births are common and serious events affecting women, families, and healthcare systems on many levels. One of the risk factors for miscarriage and preterm birth is bleeding in the first trimester of…
- Trial name
- NCT02145767
- Testing
- Progesterone
- Where
- 7 sites in Canada
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Intrauterine Adhesion
Clinical Study on a Novel Anti-adhesion Barrier Film
The aim of this clinical study was to verify the effectiveness and safety of the anti-adhesion diaphragm in preventing intrauterine adhesions.
- Trial name
- NCT05888545
- Testing
- anti-adhesion diaphragm
- Where
- 8 sites in China
- Volunteers
- 1,176 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Bleeding, Real-world Study
Post-marketing Safety and Efficacy Surveillance of Motherwort Injection
This study aims to provide evidence concerning the safety and efficacy of motherwort injection in real-world settings.
- Conditions
- Bleeding, Real-world Study, Adverse Events
- Trial name
- NCT06636422
- Testing
- Motherwort injection
- Volunteers
- 20,000 people
- Sponsor
- Zhong Wang
Early Pregnancy Loss, Intrauterine Adhesion
Operative Hysteroscopy Versus Suction Curettage for Surgical Termination of Early Pregnancy Loss (Miscarriage)
Non-blinded prospective randomized study. 100 women diagnosed with early pregnancy loss up to 10 gestational weeks who opted for surgical management (after being offered the options of conservative management and medical…
- Trial name
- NCT06309927
- Testing
- Operative hysteroscopy (by tissue removal device), Suction curettage
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Abortion, Missed
Testing the Efficiency of Karman Curette in the Treatment of Misoprostol Failure in Women With Missed Abortion
the purpose of this study is to examine the success rates of Karman curettage in completing the abortion after failed recurred treatment with Misoprostol for women with missed abortion.
- Trial name
- NCT02917785
- Testing
- Karman curettage
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Infertility and Miscarriage
A Multicenter, Prospective, Randomized, Controlled Clinical Study on the Effect of Hysteroscopic Uterine Septum Resection on the Natural Pregnancy Outcomes in Patients With Non-recurrent Spontaneous Abortion
The study aims to compare the effects of transcervical resection of septa (TCRS) and expectant management on the natural pregnancy outcomes of patients with septate uterus without recurrent abortion, also covering the treatment…
- Trial name
- NCT07039097
- Testing
- Transcervical resection of septum
- Where
- China
- Volunteers
- 418 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Spontaneous Abortion
Comprehensive Assessment of Risks for Miscarriage.
This study aims to determine the role of serum biomarkers and placental bloodflow in the comprehensive evaluation of the risk for spontaneous abortion
- Trial name
- MIS-CARE (NCT04456660)
- Testing
- Markers of ultrasound, Immunologic factors, Serum factors
- Where
- Bulgaria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Orthogyn Medical Center, Bulgaria