Clinical trials: Abortion in Second Trimester
Pregnancy Loss
Cervical Length on Pregnancy Termination
Cervical length is used as a parameter to predict cervical insufficiency and onset of labor. However, its role in predicting abortion induction is unclear.To investigate the impact of cervical length measurement and fetal…
- Trial name
- NCT04013035
- Testing
- cervical length measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pregnancy
Better Contraceptive Choices: Immediate or Delayed Insertion of IUC After Second Trimester Abortion
Hypothesis Intrauterine contraception placed immediately after a second trimester abortion will result in fewer pregnancies than current standard practice of intended placement at 4 weeks post-abortion.
- Trial name
- NCT00877344
- Testing
- Immediate insertion, Interval insertion
- Where
- 3 sites in Canada
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Abortion, Induced, Labor Stage, Third/Drug Effects
Oxytocin Infusion vs. Spontaneous Follow-up for Third-stage of Labor After Second-trimester Abortion
This study compares oxytocin infusion to spontaneous follow-up for third-stage of labor at induced mid-trimester abortions. Patients will be randomized to oxytocin infusion or observation with no pharmacologic intervention.
- Conditions
- Abortion, Induced, Labor Stage, Third/Drug Effects, Pregnancy Trimester, Second, Oxytocin/Administration & Dosage
- Trial name
- NCT02485444
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ataturk University
Induced Abortion
Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical Preparation
A randomized double---blinded comparison of same---day mifepristone and misoprostol with misoprostol only for cervical preparation in second---trimester surgical abortion in 100 women at 14 0/7---19 6/7 weeks gestation.
- Trial name
- MMSAP (NCT02412618)
- Testing
- Mifepristone, Misoprostol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Blood Loss, Surgical, Second Trimester Abortion
MisOpRostol Effect on Second Trimester Abortion Blood Loss
Although serious complications from second trimester abortion are rare hemorrhage is the most common cause of procedural abortion related morbidity and mortality.
- Trial name
- MORESTABL (NCT06078501)
- Testing
- Misoprostol 400mcg buccal
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Stanford University
Cervical Ripening
Misoprostol Versus Dilapan-S for Cervical Preparation
The purpose of this study is to compare the dilatory effect of 400 mcg of buccally administered misoprostol to one Dilapan-S rod placed 3-4 hours before abortion by dilation and evacuation in women who are 12 weeks 0 days to 15…
- Trial name
- NCT00835731
- Testing
- misoprostol, Dilapan-S, vitamin B-12
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Termination of Pregnancy (TOP)
Interest of Cervical Dilators in Second Trimester Termination of Pregnancy
The purpose of this study is to evaluate whether the use of cervical dilators for cervical ripening in case of second trimester medical termination of pregnancy (TOP) is effective to reduce duration of labor.
- Trial name
- DILATOP (NCT03194230)
- Testing
- With cervical dilatator
- Where
- France
- Volunteers
- 355 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abortion
Comparative Psychiatric Problems Between First and Second Trimester Miscarriage
Description of the psychiatric impact of miscarriage on women.
- Trial name
- NCT06742632
- Testing
- Symptoms checklist-90
- Where
- Egypt
- Volunteers
- 155 people
- Sponsor
- Assiut University
Abortion in Second Trimester
Mifepristone and Misoprostol for Midtrimester Termination of Pregnancy in Uzbekistan
The primary goal is to examine the efficacy and feasibility of a mifepristone-misoprostol medical abortion regimen in terminating pregnancies 13-22 weeks in Uzbekistan.
- Trial name
- NCT02235155
- Where
- 3 sites in Uzbekistan
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Late Second Trimester Termination of Pregnancy
Vaginal Misoprostol and Foley Catheter for Late Second Trimester Termination of Pregnancy
Vaginal Misoprostol Versus Combined Low Dose Misoprostol Plus Foley Catheter for Late Second Trimester Termination of Pregnancy With Previous Multiple Cesarean Sections
- Trial name
- NCT02989324
- Testing
- MisoprostoL, Foley Catheter
- Where
- Egypt
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Abortion, Blood Loss
Effect of Preoperative Buccal Misoprostol on Blood Loss in Second-trimester Dilation and Evacuation Abortion
Misoprostol is a medication used extensively in obstetrics and gynecology for its ability to aid in softening the cervix as well as decreasing blood loss after abortion or vaginal delivery.
- Trial name
- PreopMiso (NCT01436266)
- Testing
- Misoprostol, Folic acid
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Boston University
Miscarriage
Could Colour Dopper Improve the Diagnosis of Retained Placental Fragments After Second Trimester Miscarriage ?
Value of pelvi- abdominal ultrasound and Doppler in diagnosis of retained products of conception after second trimester miscarriage to select who will benefit from surgical evacuations or conservative management.
- Trial name
- NCT02419300
- Testing
- ultrasoungraphy
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Ain Shams University
Abortion Early
Mid Trimester Abortion Effectiveness by Dilapan s
This study is done aiming to find out an effective method to induce second trimester abortion within a reasonable time and with the least possible cost and complications.
- Trial name
- NCT05147857
- Testing
- Dilapan s, Misoprostol
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Abortion Second Trimester
Overnight Pain Treatment Investigating Opioids vs. Nonopioids
The purpose of this study is to compare maximum pain scores between patients seeking induced abortion and requiring cervical preparation with osmotic dilators.
- Trial name
- OPTION (NCT03545893)
- Testing
- Ibuprofen 600 mg, OxyCODONE 5 Mg Oral Tablet
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Pennsylvania
Termination of Pregnancy
Comparison of Surgical Versus Medical Termination of Pregnancy Between 13-20 Weeks of Gestation in Ethiopia
The purpose of the study is to determine the safety and effectiveness of dilation and evacuation for surgical abortion as compared to medical abortion
- Trial name
- NCT04602052
- Testing
- Dilation and evacuation
- Where
- Ethiopia
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- St. Paul's Hospital Millennium Medical College, Ethiopia
Lactation Suppressed, Second Trimester Abortion
Pharmacological Inhibition of Lactation After 16 to 20 Week Abortion
The goal of this clinical trial is to compare breast symptoms (lactation, engorgement, etc) of individuals who undergo a procedure for second trimester of pregnancy loss between 16 weeks and 20 weeks gestational age.
- Trial name
- NCT06123026
- Testing
- Cabergoline
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Abortion Induced Complicated, Abortion
Second Trimester Abortion With Letrozole and Misoprostol Compared to Misoprostol Alone
Termination of Second trimester Abortion with Letrozole and Misoprostol Compared to Misoprostol Alone
- Trial name
- NCT07767435
- Testing
- · Misoprostol + letrozole, misoprostol alone
- Volunteers
- 80 people
- Sponsor
- Sohag University
Retained Placenta
Management of Third-stage of Labor After Second Trimester Medical Pregnancy Termination
Prospective randomized trail which compare 2 regimens for third-stage management after second trimester medical pregnancy termination : 10UI intra venous oxytocin or no additional medication after fetal expulsion.
- Trial name
- ANDDROID (NCT02969447)
- Testing
- Administration of 10 units of intra venous oxytocin after fetal expulsion
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Bordeaux
Contraception Behavior
Immediate vs. Delayed Insertion of Copper T 380A IUD After Termination of Pregnancy Over 12-weeks Gestation
The purpose of this study is to compare delayed vs. immediate insertion of the Copper T 380 IUD after termination of pregnancy after 12 weeks.
- Trial name
- NCT00540046
- Testing
- Copper T 380A IUD
- Where
- 2 sites in United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Arrhythmia, ECG Changes
Intra Amniotic Injection of DIGOXIN for Feticide in Second Trimester Termination of Pregnancy
In second trimester abortion above 22 weeks the investigators usually inject intra-cardiac Kcl for feticide. Digoxin intra-amniotic injection has been described in the literature in doses of 1-1.5 mg.
- Conditions
- Arrhythmia, ECG Changes, Hypotension
- Trial name
- NCT01951079
- Testing
- Intra-amniotic injection of DIGOXIN
- Where
- 2 sites in Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center