Clinical trials: Abortion in Second Trimester
Lactation Suppressed, Second Trimester Abortion
Pharmacological Inhibition of Lactation After 16 to 20 Week Abortion
The goal of this clinical trial is to compare breast symptoms (lactation, engorgement, etc) of individuals who undergo a procedure for second trimester of pregnancy loss between 16 weeks and 20 weeks gestational age.
- Trial name
- NCT06123026
- Testing
- Cabergoline
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Abortion, Second Trimester, PPROM
Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial
When time allows, administration of mifepristone prior to second trimester induction of labor decreases total labor time. However, in the setting of many pregnancy complications, decreasing time from diagnosis of nonviable…
- Conditions
- Abortion, Second Trimester, PPROM, Rupture, Spontaneous, Fetal Demise
- Trial name
- MIST (NCT05322252)
- Testing
- Mifepristone, Misoprostol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington University School of Medicine
Blood Loss, Surgical, Second Trimester Abortion
MisOpRostol Effect on Second Trimester Abortion Blood Loss
Although serious complications from second trimester abortion are rare hemorrhage is the most common cause of procedural abortion related morbidity and mortality.
- Trial name
- MORESTABL (NCT06078501)
- Testing
- Misoprostol 400mcg buccal
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Stanford University
Abortion, Second Trimester
Transcervical Balloon Compared to Osmotic Dilators Prior to Surgical Abortion
The purpose of this study is to determine whether a Foley balloon is similar to osmotic dilators for preparing the cervix prior to a second trimester abortion.
- Trial name
- NCT05099991
- Testing
- Single Foley Balloon, Dilapan-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Stanford University
Second Trimester Abortion
Cervical Preparation With Mifepristone Prior to Osmotic Dilators
The investigators plan to study the role of mifepristone prior to the placement of cervical osmotic dilators to evaluate if the medication helps increase the number of dilators.
- Trial name
- NCT03714880
- Testing
- Mifepristone 200 MG
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Second Trimester Abortion
Laminaria Compared to Dilapan-S for Cervical Preparation Before Dilation and Evacuation at 18-24 Weeks of Gestation
Primary objective: To study the difference in dilation and evacuation (D\&E) procedure time following overnight cervical preparation with laminaria or Dilapan-S™.
- Trial name
- NCT02033083
- Testing
- Laminaria, Dilapan-S
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
Abortion Second Trimester
Overnight Pain Treatment Investigating Opioids vs. Nonopioids
The purpose of this study is to compare maximum pain scores between patients seeking induced abortion and requiring cervical preparation with osmotic dilators.
- Trial name
- OPTION (NCT03545893)
- Testing
- Ibuprofen 600 mg, OxyCODONE 5 Mg Oral Tablet
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Pennsylvania
Abortion, Second Trimester
24-hour Mifepristone and Buccal Versus Mifepristone and Vaginal Misoprostol for Cervical Preparation for D&E
This study aims to compare mifepristone and buccal misoprostol to mifepristone and vaginal misoprostol for cervical preparation for second trimester dilation and evacuation (D\&E).
- Trial name
- NCT03134183
- Testing
- Vaginal Misoprostol, Buccal Misoprostol
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University