Clinical trials: Abrasion
Gingival Recession, Localized, Tooth Abrasion
Use of a Novel Volume-stable Collagen Matrix (VCMX) in the Treatment of Single Gingival Recession Associated With Non-carious Cervical Lesion Partially Restored
Gingival recessions (GR) are often associated with non-carious cervical lesions (NCCL), resulting, thus, in a combined defect. This mucogingival condition has a different treatment prognosis when compared with a GR without…
- Trial name
- NCT05916716
- Testing
- Restorative procedure, Coronally Advanced Flap (CAF)., Volume-stable collagen matrix (VCMX)
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Healthy
Meals and Grazing Study
The purpose of this study was to determine the effects of low vs. high eating frequency (EF) on biomarkers of health and subjective appetite.
- Trial name
- MAGS (NCT02548026)
- Testing
- High Eating Frequency (High EF), Low Eating Frequency (Low EF)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Leg Ulcer, Diabetic Foot Ulcer
Study to Examine Clinical Performance and Safety of Cutimed® Gelling Fiber in Routine Clinical Practice
This is a post - market study with a wound dressing, a CE-marked medical device available on the european market. The device will be used in routine clinical practice, i.e.
- Conditions
- Leg Ulcer, Diabetic Foot Ulcer, Pressure Ulcer, Surgical Wound
- Trial name
- GELFI (NCT05148390)
- Testing
- Cutimed® Gelling Fiber
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- BSN Medical GmbH
Hypersensitivity Dentin, Tooth Hypersensitivity
Effectiveness of Bioactiveglass Air Abrasion Versus Fluoride Varnish in Management of Dentin Hypersensitivity
Will the use of Bioactive glass with air abrasion technology (Sylc) compared to Fluoride Varnish (Biflourid 10) affects the degree of pain in patients complaining from hypersensitivity due to non-carious lesions?
- Trial name
- NCT03285360
- Testing
- Sylc, fluoride varnish (Bifluorid 10)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries; Initial, Pit and Fissure Caries
Retention Rate of Self-etch Resin Based Sealant With and Without Prior Sandblasting
The aim of the study is to clinically assess the effect of sandblasting prior to self-etch resin based sealant on its retention after one year follow up.
- Trial name
- NCT04929327
- Testing
- Self etch Pit and fissure sealant application (prevent seal), Self etch Pit and fissure sealant application (prevent seal) with prior sandblasting, Total etch resin based sealant ultraseal xt
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spontaneous Pneumothorax, Idiopathic Pneumothorax
Thoracoscopy for Idiopathic Pneumothorax in Children
The goal of this retrospective study is to describe the outcomes of spontaneous idiopathic pneumothorax treated by thoracoscopy with pleural abrasion and blebectomy.
- Conditions
- Spontaneous Pneumothorax, Idiopathic Pneumothorax, Bleb Lung, Child, Only
- Trial name
- THOPED (NCT06734442)
- Testing
- Video-Assisted Thoracoscopy with blebectomy and pleural abrasion
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Clermont-Ferrand
Corneal Abrasion
Bandage Contact Lens Application for the Management of Corneal Abrasion
The researchers are trying to understand if the application of a bandage contact lens results in better relief than usual treatment for a corneal abrasion.
- Trial name
- NCT04159714
- Testing
- Air Optix contact lens
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Corneal Abrasions
IN PATIENTS WITH CORNEAL ABRASIONS TREATED WITH COLLAGEN CORNEAL SHIELDS IN THE EMERGENCY DEPARTMENT SETTING
This is a single-center, double-arm, patient masked, randomized controlled trial. Subjects will be enrolled in the Emergency Department at the Penn State Milton S. Hershey Medical Center.
- Trial name
- NCT07225699
- Testing
- Oasis 72-Hour collagen shield
- Volunteers
- 60 people
- Sponsor
- Milton S. Hershey Medical Center
Gum Injury
Assessing Effects of a Denture Gel on Gum Abrasions
This is a parallel design study. Up to 40 subjects with a full mandibular and full maxillary dentures will be enrolled into the study. Subjects will use their current denture care +/- a treatment gel for 4 weeks.
- Trial name
- NCT04913636
- Testing
- Treatment Gel
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Corneal Abrasion
Effect of Tetracaine on Pain Management and Corneal Healing in Patients With Acute Corneal Abrasion
Corneal abrasions are associated with significant discomfort during a 24-48 hrs healing phase. Current practice guidelines discourage the use of topical anesthetics in treating these patients due to concerns that these…
- Trial name
- NCT02483897
- Testing
- Tetracaine 0.5% ophthalmic drops
- Sponsor
- Queen's University
Periodontal Diseases
Impact of Full Mouth Erythritol Powder Air Polishing on Systemic Inflammatory Response
Periodontitis (PD) is an inflammatory condition that affects 20%-50% of the total global population, with severe disease occurring in 9.8% of individuals.
- Trial name
- NCT05812391
- Testing
- test, conventional
- Where
- Iraq
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Junctional Epidermolysis Bullosa, Epidermolysis Bullosa (EB)
Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa
This study consists of two phases: an Observational Phase to evaluate the natural history of ocular manifestations in subjects with Dystrophic and Junctional Epidermolysis Bullosa, followed by a Treatment Phase to assess the…
- Conditions
- Junctional Epidermolysis Bullosa, Epidermolysis Bullosa (EB), Dystrophic Epidermolysis Bullosa, Recessive Dystrophic Epidermolysis Bullosa
- Trial name
- GOTAS-ELK-EB (NCT06713434)
- Testing
- ELK-003 (Standarized Amniotic Fluid Secretome Eye Drops)
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Fundación DEBRA Chile, Niños Piel de Cristal
Gingival Recession, Tooth Abrasion
A New Surgical-restorative Approach to Treat Gingival Recessions Associated With Non-carious Cervical Lesions (NCCL)
The aim of the present study is to evaluate the clinical, aesthetic and patient-centered parameters of connective tissue graft associated or not with partial resin composite (RC) for the treatment of gingival recession with NCCL…
- Trial name
- NCT02817763
- Testing
- Connective tissue graft (CTG), CTG plus resin composite restoration, sodium dipyrone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Quality of Life, Cervical Abrasion
The Role of Biodentine in Class V Dental Lesions on Oral Health Related Quality of Life
The study will compare two different dental materials on dental lesions near the gum line that cause chronic pain on oral health related quality of life.
- Trial name
- NCT03304184
- Testing
- Photac-fil, Biodentine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Michigan
Skin Wounds, Abrasion
A Study to Evaluate the Safety and Clinical Performance of a Dexpanthenol Medicated Hydrogel Patch in the Treatment of Standardized Superficial Abrasions
Clinical evaluation of a Dexpanthenol-medicated wound plaster on standardized superficial skin abrasions
- Trial name
- Dexpanthenol (NCT07642973)
- Testing
- hydrogel plaster with dexpanthenol, Standard plaster
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wooshin Labottach Co., Ltd.
Eyes Dry Chronic, Chronic Conjunctivitis of Both Eyes
CDL Validation Study
Ocular surface photography is significantly limited in standardization and reproducibility. This reduces its applicability for clinical monitoring of acute or chronic disease.
- Conditions
- Eyes Dry Chronic, Chronic Conjunctivitis of Both Eyes, Limbal Stem-cell Deficiency, Eye Lesion
- Trial name
- NCT05461469
- Where
- Austria
- Volunteers
- 104 people
- Sponsor
- Occyo GmbH
Skin Laceration, Skin Abrasion
Retrospective, Observationnal Study to Investigate Procedural Analgesia Delivered to Patients With Lacerations, Abrasions, Burns and Leg Ulcers.
The main part of the study is a retrospective analysis of 200 reports concerning patients with skin wounds and injuries : 50 consecutive patient reports dealing with skin lacerations 50 consecutive patient reports dealing with…
- Conditions
- Skin Laceration, Skin Abrasion, Skin Burn, Leg Ulcer
- Trial name
- APPABU (NCT07350811)
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Versailles Hospital
Hyperkalaemia
Study of SZC and Enhanced Nutrition Advice Compared to SoC in Dialysis Patients With Hyperkalaemia
Prescribing Sodium zirconium cyclosilicate (SZC) with enhanced nutritional advice to participants with hyperkalaemia on haemodialysis will reduce serum K+ (S-K+ ) and enable the consumption of more fruit and vegetables and more…
- Trial name
- GRAZE (NCT04997161)
- Testing
- Sodium Zirconium Cyclosilicate (SZC), Enhanced dietary advice, Standard dietary advice including K+ restriction.
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- AstraZeneca
Pneumothorax
Pleural Abrasion Plus Minocycline Versus Apical Pleurectomy for Primary Spontaneous Pneumothorax
Optimal surgical management of primary spontaneous pneumothorax has been a matter of devate, especially regarding the method of pleurodesis.
- Trial name
- NCT00270751
- Testing
- 1 apical pleurectomy, 2 pleural abrasion + minocycline pleurodesis
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Irritation/Irritant
21 Day Cumulative Skin Irritation of RUT058-60
The purpose of this study is to determine the skin irritation potential of RUT058-60 after repetitive patch application to abraded and non-abraded skin of human subjects.
- Trial name
- NCT02198963
- Testing
- Hypochlorous acid solution 106 mg/L, 0.1% (w/v) Sodium Lauryl Sulfate, 0.9% Physiological Saline, USP
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pulmatrix Inc.