Clinical trials: Abuse Cannabis
HIV Infections
Integrated Treatment of Marijuana Abuse for HIV+ Youth
This is an exploratory study that will adapt and test a combined cognitive behavioral treatment and contingency management intervention for alcohol and/or marijuana abuse for use in HIV-infected adolescents.
- Trial name
- NCT00683488
- Testing
- Focus Group, First Intervention Trial, Intervention Trial 2
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- University of North Carolina, Chapel Hill
Cannabis Use
Electrophysiological Study of the Functioning of Magnocellular Visual Pathway in Regular Cannabis Users
This study will evaluate the impact of regular use of cannabis on the spatial sensitivity of magnocellular system (visual event-related potential, visual ERP).
- Trial name
- CAUSA MAP (NCT02864680)
- Testing
- Electroretinography, Contrast sensitivity test during Electroencephalography, Visual simultaneity test during Electroencephalography
- Where
- France
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Behavior, Addictive
The Effectiveness of a Brief Motivational Nursing Intervention
This was a two-staged study undertaken in entertainment-sector workers in Spain: the first part was transversal and observational, and the second was semi-experimental.
- Trial name
- BMNI (NCT04125303)
- Testing
- brief motivational psychoeducational therapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Cardenal Herrera University
Driving Behavior, Driving Under the Influence
Validation of the Drug Impaired Driving Scenario (DIDS) on the CRCDS-miniSim
Subjects will participate in a 4-visit study protocol at the National Advanced Driving Simulator, part of the University of Iowa, in which they will be asked to complete assorted questionnaires, computerized cognitive tasks, and…
- Trial name
- PDID (NCT04970342)
- Testing
- 0.75 mg Alprazolam Capsule, Cannabis (6.18% THC / <0.025% CBD), Cannabis (0%/ THC / 0% CBD)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Timothy L. Brown
Marijuana Abuse
Treatment for Adolescent Marijuana Abuse
Marijuana remains the most prevalent illicit substance used by adolescents and the number of adolescents receiving treatment for marijuana abuse more than tripled during the last decade.
- Trial name
- NCT00580671
- Testing
- MET/CBT, CM, BPT
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cannabis, Marijuana Use
Developing and Strengthening Cannabis Warnings: Warning Message Testing
The purpose of this activity is to identify promising cannabis warning messages from different themes. Participants will be adults who live in the United States, including both people who use cannabis and those who do not use…
- Trial name
- NCT07699198
- Testing
- Constituents, Cognitive Functioning, Cardiovascular Health
- Where
- United States
- Volunteers
- 1,750 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy
Single and Multiple Dose Study of VER-01 in Healthy Volunteers
Evaluation of pharmacokinetics, tolerability and safety of VER-01 in healthy volunteers
- Trial name
- NCT04930809
- Testing
- VER-01
- Where
- Austria
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vertanical GmbH
Cannabis Use Disorder, Repetitive Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation to People With Cannabis Use Disorder (SToP-C-rTMS x CUD)
This study is to explore if repetitive transcrinal magnetic stimulation (rTMS) with different stimulation schedules will be equally effective in reducing carving, frequency of cannabis use, and the severity of cannabis use…
- Trial name
- NCT05292547
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Marijuana Dependence
The Effects of Marijuana on Orientation and Motor Coordination and Brain Metabolism in Regular Smokers of Marijuana
This study investigates the effects of 17mg and 13mg Delta THC on orientation and motor coordination and brain metabolic activity in regular users of marijuana.
- Trial name
- NCT00270803
- Testing
- Tetra Hydro Cannabinol (THC)
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Marijuana Abuse, Substance-Related Disorders
Effectiveness of Bupropion in Treating Marijuana Dependent Individuals
A definable and significant withdrawal syndrome occurs upon cessation of chronic, heavy marijuana use. Bupropion (Zyban) is a medication currently used to treat withdrawal symptoms associated with tobacco use.
- Trial name
- NCT00142870
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cannabis Use Disorder
Evaluation of the Effects of Cannabidiol (CBD) Compared to Delta-9-Tetrahydrocannabinol (THC) and Alprazolam
The purpose of this study is to evaluate the abuse potential of CBD to determine whether it should remain as a Schedule I drug under the Controlled Substances Act, or be recommended for decontrol.
- Trial name
- NCT03398083
- Testing
- THC, Alprazolam, CBD
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cigarette Smoking, Marijuana Abuse
Mobile Contingency Management for Marijuana and Tobacco Cessation
The purpose of this pilot project is to pilot-test a combined cannabis and smoking cessation treatment. The intervention combines mobile technology with behavioral strategies, counseling, and medications.
- Trial name
- NCT02869451
- Testing
- bupropion, transdermal nicotine patch, Nicotine polacrilex
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University
Cannabis Use
Environment and Lung Cancer
Cannabis is the most consumed drug in the world and the French are the main consumers in Europe. The most recognized effects of cannabis on human health are of a neuro-psychic nature.
- Trial name
- ECP (NCT05119244)
- Testing
- blood and hair sampling
- Where
- 3 sites in France
- Volunteers
- 150 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Pain, Cannabis
Enhancing Medication-based Analgesia in Humans
This is a single-group, within-subject, double-blind, double-dummy, placebo and active-controlled study evaluated whether the FDA-approved cannabinoid dronabinol (Marinol) would enhance analgesia, subjective reports, and…
- Conditions
- Pain, Cannabis, Opioid Use, Unspecified
- Trial name
- NCT02901275
- Testing
- Within-subject test of blinded study medications
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy Volunteer
Challenging the Endocannabinoid System in Sleep Restricted Healthy Volunteers to Modulate Physiological Arousal (CANISLEEP) Study
The goal of this study is to learn about the body's response to cannabis based products in sleep deprived people who are currently experiencing anxiety but are otherwise healthy.
- Trial name
- CANISLEEP (NCT07656350)
- Testing
- THC, CBD, THC + CBD
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King's College London
Cocaine Dependence, Cocaine Use Disorder
Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting
This study was an internal program effectiveness evaluation of the effects of a four-session weekly individualized cognitive therapy program (called the "Mind Freedom Plan" (MFP)) on substance use outcomes and substance abuse…
- Conditions
- Cocaine Dependence, Cocaine Use Disorder, Opiate Dependence, Opioid-use Disorder
- Trial name
- NCT03662529
- Testing
- Four-Session Mind Freedom Plan, Treatment as usual therapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Cannabis Intoxication
Exploring The Effect Of Cannabidiol On Cannabis Tolerance Using A Novel Vaporiser Device In Heavy Users (Stage 1)
Cannabis contains delta-9-tetrahydrocannabinol (THC), which causes intoxication. People who use cannabis frequently often develop tolerance, meaning they need to use more THC to feel the same effects.
- Trial name
- ENDURANCE (NCT07471347)
- Testing
- delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- King's College London
Cannabis Use Disorder
Use of a Mobile Health Sensor in an Open Label Trial of Lorcaserin for the Treatment of Cannabis Use Disorder
This is a 10 week, open-label, prospective study, involving 10 volunteer participants with cannabis use disorder to test the feasibility and safety of using lorcaserin in addition to the feasibility, likability, and utility of a…
- Trial name
- NCT02932215
- Testing
- lorcaserin, Fitbit Charge HR
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- New York State Psychiatric Institute
Malnutrition, Anorexia
Sativex® and Gentamicin for Optimized Pharmagological Treatment in Older Patients (CanPan)
Malnutrition and inappropriate prescribing of renally excreted drugs are common among older persons and are associated with severe consequences such as complicated courses of treatment, mortality, and reduced quality of life.
- Conditions
- Malnutrition, Anorexia, Cannabis, Aging
- Trial name
- CanPan (NCT05503147)
- Testing
- Sativex
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- Ove Andersen
Cannabis
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study II
The purpose of the study is to characterize the acute effects of cannabinoids in women relative to men and to begin probing the mechanisms that may underlie gender differences.
- Trial name
- THC-Gender-II (NCT04704271)
- Testing
- Inhaled THC
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yale University