Clinical trials: Abuse Tobacco
Nicotine Withdrawal, Marijuana Dependence
Medications Development for the Treatment of Cannabis Related Disorders
The primary objective of this application is to test the neurobehavioral mechanisms and effects of aprepitant as a new cessation agent for cannabis, tobacco or both.
- Conditions
- Nicotine Withdrawal, Marijuana Dependence, Cannabis Dependence, Nicotine Dependence
- Trial name
- MTC (NCT01204723)
- Testing
- Active Aprepitant
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Tobacco Use Disorder
Optimizing Tobacco Dependence Treatment in the Emergency Department
The investigators propose an innovative full-factorial design in a cohort of 1056 adult smokers in an urban emergency department (ED), to test the efficacy of four key intervention components: motivational interviewing…
- Trial name
- NCT02896400
- Testing
- Brief Negotiated Interview (BNI), Nicotine replacement therapy (NRT), CT Smokers Quitline (QL)
- Where
- United States
- Volunteers
- 1,056 people
- Sponsor
- Yale University
Smoking
Korean Youth Smoking Cessation Study
Cigarette smoking remains the leading preventable cause of morbidity and mortality in the United States. In Los Angeles, rates of morbidities due to cigarette smoking follow prevalence.
- Trial name
- NCT02021175
- Testing
- Tailored CBME Therapy via Technology, Standard of Care
- Where
- United States
- Sponsor
- University of California, Los Angeles
Tobacco Use Disorder, Alcohol Dependence
Intensive Intervention for Smokers - 6
The purpose of this study was to determine the efficacy and cost-effectiveness of an intensive smoking cessation intervention that utilizes extended cognitive-behavioral therapy and combination nicotine replacement (CNR) in a…
- Trial name
- NCT00217984
- Testing
- Usual Care, Extended cognitive behavior therapy
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- University of California, San Francisco
Nicotine Dependence
Manipulating Tobacco Constituents in Female Menthol Smokers
This study examines the potential effect of reducing nicotine content or menthol or both in women of reproductive age, a vulnerable population identified by the FDA in need of further research.
- Trial name
- Menthol (NCT02048852)
- Testing
- Reduced Nicotine Content- Non Menthol, Reduced Nicotine Content- Menthol, Conventional Nicotine Content- Menthol
- Where
- 2 sites in United States
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- UConn Health
Smoking, Nicotine Dependence
Helping Those With Mental Illness Quit Smoking
This study tests whether pre-cessation interventions known to be effective in the general population will increase acceptance of evidence-based treatment, engagement and compliance with that treatment and initial quitting…
- Conditions
- Smoking, Nicotine Dependence, Mental Disorders
- Trial name
- NCT01783912
- Testing
- Cognitive / Motivational Individual Sessions, Attention Control Individual Sessions, Nicotine Patch
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Wisconsin, Madison
Hospitalized Smokers, Chronic Diseases
Enhancing Tobacco Abstinence Following Hospitalization
The primary aim of this study is to examine the efficacy of a 12-week nurse-delivered relapse management intervention designed with conceptual underpinnings from Self-efficacy Theory to enhance smoking abstinence of hospitalized…
- Conditions
- Hospitalized Smokers, Chronic Diseases, Tobacco Use Disorder
- Trial name
- NCT00222703
- Testing
- Smoking relapse prevention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Nicotine Dependence, Tobacco Smoking
Smoking Cessation and Menstrual Cycle Phase
Tobacco use is a risk factor for at least 20 types of cancer and remains the leading preventable cause of cancer in Canada. Smoking cessation is an important cancer prevention strategy for the close to 2 million Canadian women…
- Conditions
- Nicotine Dependence, Tobacco Smoking, Smoking Cessation, Nicotine Use Disorder
- Trial name
- MC-NRT (NCT05515354)
- Testing
- Timing of nicotine replacement therapy start date, Nicotine Replacement Therapy Agent
- Where
- Canada
- Volunteers
- 1,200 people
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Use Disorder
Project 4, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Pregnant Women
Study 2 will evaluate the effects of extended exposure to cigarettes with varying levels of nicotine in pregnant smokers who have less than an Associate's degree. This study will be limited to two conditions: usual brand vs.
- Trial name
- NCT04033237
- Testing
- Very low nicotine content cigarettes
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Nicotine Dependence
Study on Sit to Quit Phone Intervention
This study is designed to test the effectiveness of the smoking cessation intervention "Sit to Quit" through a randomized-control trial.
- Trial name
- NCT02840435
- Testing
- Sit to Quit, Quit for Life
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Duke University
Smokers
Nicotine Patch Safety Study
The purpose of this study is to evaluate the safety profile of a repeated application of a new transdermal patch compared to a reference product during 3 weeks, in a large population.
- Trial name
- NCT01655082
- Testing
- V0116 transdermal patch, Nicotine transdermal patch
- Where
- 4 sites in France
- Volunteers
- 160 people
- Sponsor
- Pierre Fabre Medicament
Tobacco Use Disorder
Comparison Across Treatment Conditions to Reduce Smokeless Tobacco Use
Smokeless tobacco (ST), which includes both chewing tobacco and snuff, has health risks associated with its use. While treatment programs that focus on stopping tobacco use may be effective, past research has shown that…
- Trial name
- NCT00218296
- Testing
- Usual Care Group, Reduction Group
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Dependence
Comparative Pharmacokinetic Study of New Oral Nicotine Replacement Therapy Products.
Comparative pharmacokinetic study of new oral nicotine replacement therapy products.
- Trial name
- NCT01227720
- Testing
- Experimental Nicotine Replacement Therapy (NRT) 2 mg, Experimental Nicotine Replacement Therapy (NRT), Marketed Nicotine Lozenge
- Where
- 2 sites in Sweden
- Volunteers
- 104 people
- Sponsor
- McNeil AB
Tobacco Use Cessation, Tobacco Use
Reach Through Equitable Implementation in Utah
The goal of this pragmatic, multilevel Type III Hybrid Effectiveness-Implementation trial is to increase the reach of existing evidence-based interventions (EBIs) for tobacco cessation and to mitigate the impact of adverse Social…
- Conditions
- Tobacco Use Cessation, Tobacco Use, Tobacco Smoking, Tobacco Chewing
- Trial name
- REI-UT (NCT06881069)
- Testing
- Clinic Level: AAC - SDOH, AAC - Tobacco, Non-Bundled, Bundled
- Where
- United States
- Volunteers
- 1,560 people
- Sponsor
- University of Utah
Tobacco Use Cessation, Smoking Cessation
Treating Low-Income Smokers in the Hospital Emergency Department
This study will test the effectiveness of an Emergency Department (ED) initiated tobacco intervention which includes counseling and medication.
- Conditions
- Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
- Trial name
- NCT01328431
- Testing
- Brief Intervention with NRT Initiation
- Where
- United States
- Volunteers
- 780 people
- Sponsor
- Yale University
Nicotine Dependence, Cigarettes, Cessation, Tobacco
Reducing Nicotine Addiction in Adolescent Smokers
Adolescents are at risk for tobacco use due to factors such as impulsivity, poor perception, desire to prove themselves, and insufficient neurological development.
- Conditions
- Nicotine Dependence, Cigarettes, Cessation, Tobacco, Cessation, Smoking, Adolescent Problem Behavior
- Trial name
- NCT05477342
- Testing
- Board Game, Tobacco Cesseation Education, Combined İntervention
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Ministry of National Education, Turkey
HIV/AIDS, Nicotine Dependence
Optimizing Tobacco Use Treatment for PLWHA
The advent of anti-retroviral therapy (ART) for people living with HIV/AIDS (PLWHA) substantially improved life expectancy but has also led to the critical need to address modifiable risk factors associated with cancer and…
- Trial name
- HTO (NCT04176172)
- Testing
- Varenicline, Nicotine patch, Standard treatment
- Where
- 2 sites in United States
- Volunteers
- 340 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Tobacco Dependence
Improving Health for Aboriginal People Through Tobacco Related Research
Aim: To identify barriers and facilitators in the uptake of smoking cessation pharmacotherapies, tobacco prevention, doctor visits, smoking amongst youth, community held health priorities and barriers to research in Aboriginal…
- Trial name
- NCT01735448
- Testing
- Focus group, One-on-one interviews, Survey
- Where
- 3 sites in Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Queen Elizabeth Hospital
Tobacco Use Disorder, Nicotine Dependence, Cigarettes
Effects of Nicotine Dependence on Multidimensional Health Outcomes
Nicotine, a major toxic component of cigarette smoke, together with carbon monoxide (CO), constitutes a significant environmental exposure with systemic effects.
- Trial name
- NCT07474623
- Testing
- Comprehensive Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Tobacco Use Disorder
Bupropion and Weight Control for Smoking Cessation - 1
The purpose of this study is to determine whether the addition of bupropion (Zyban) to cognitive behavioral therapy (CBT) will enhance longer-term tobacco abstinence in women.
- Trial name
- NCT00006170
- Testing
- Bupropion, weight concerns intervention, smoking cessation intervention
- Where
- United States
- Volunteers
- 349 people
- Sponsor
- University of Pittsburgh
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.