Clinical trials: Abuse Tobacco
Smoking Cessation; Tobacco Dependence
Smoking Cessation Program With CBT and Mindfulness Audio Support: A Randomized Controlled Trial
This protocol describes a randomized controlled trial evaluating the effectiveness of a smoking cessation program with two intervention methods.
- Trial name
- NCT06901713
- Testing
- cognitive behaviour thearpy, mindfulness
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Sir Run Run Shaw Hospital
Cancer, Tobacco Dependence
Tobacco Cessation Care for Cancer Patients by Automated Interactive Outreach
This is a multi-arm, randomized controlled, pilot study which will recruit cancer patients who have been seen by a UCSF Cancer Center-affiliated clinical department to evaluate the efficacy of "CareConnect".
- Conditions
- Cancer, Tobacco Dependence, Tobacco Use Cessation
- Trial name
- NCT05829824
- Testing
- CareConnect, AutoReach, Biospecimen samples
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of California, San Francisco
Positron Emission Tomography
Brain Nicotine Receptor Density in Veteran Smokers
Cigarette smoking is more prevalent among Veterans (27%) than the general U.S. population (21%). Smoking is common among people who use marijuana or caffeine heavily, and the use of menthol cigarettes is becoming increasingly…
- Trial name
- BNRDVS (NCT01721473)
- Testing
- positron emission tomography scan
- Where
- 2 sites in United States
- Volunteers
- 184 people
- Sponsor
- VA Office of Research and Development
Nicotine Dependence, Cigarette Smoking
Lemongrass (Cymbopogon Citratus) on Nicotine Dependence, Cotinine Levels, and Related Biomarkers in Adult Smokers
The goal of this clinical trial is to learn whether lemongrass (Cymbopogon citratus) inhaler and liquid vapor interventions affect nicotine dependence and related biological and behavioral outcomes in adult smokers.
- Conditions
- Nicotine Dependence, Cigarette Smoking, Tobacco Use Disorder, Psychological Stress
- Trial name
- CCIVS (NCT07366294)
- Testing
- Lemongrass Inhaler, Lemongrass Liquid Vapor, Lemongrass Inhaler and Liquid Vapor
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Titin Andri Wihastuti
Nicotine Dependence
Zonisamide Augmentation of Varenicline Treatment for Smoking Cessation
Randomized trial to evaluate whether zonisamide can enhance varenicline-induced smoking cessation.
- Trial name
- 1207 (NCT01685996)
- Testing
- zonisamide
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Johns Hopkins University
Nicotine Addiction
A Smoking Intervention Study Using Scheduled Gradual Reduction With Varenicline to Help With Cessation
This study has three main aims. Aim 1: To provide initial data on the efficacy of combined Scheduled Gradual Reduction (SGR) and Varenicline (VN) for smoking cessation, by assessing abstinence and levels of smoking at 2 time…
- Trial name
- NCT01772641
- Testing
- Scheduled Gradual Reduction + Varenicline, Basic Advice + Varenicline
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Dysfunctional Breathing, Physical Activity
Prevalence and Association of Dysfunctional Breathing With Nicotine Dependence and Physical Activity Among Young Smokers
We will structure the study's summary to provide a clear and accessible overview for patients, families, and healthcare providers.
- Conditions
- Dysfunctional Breathing, Physical Activity, Nicotine Dependence
- Trial name
- NCT07843524
- Testing
- Observational evaluation.
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Istinye University
Tobacco Use Disorder
Efficacy of Varenicline for Smokeless Tobacco Use in India
This study, based in India, is testing the efficacy of varenicline to help smokeless tobacco users with cessation efforts.
- Trial name
- NCT01098305
- Testing
- Varenicline, Counseling
- Where
- India
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tobacco Use Disorder
Progesterone for Smoking Relapse Prevention Following Delivery
Smoking is the main preventable cause of mortality in Western countries, contributing to over 430,000 deaths a year in the U.S. alone.
- Trial name
- NCT01972464
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Yale University
Tobacco Dependence
Evaluation of the Safety Profile, Quit and Reduction Rate After Nicorette® Gum and Patch Treatment
To evaluate the safety, smoking cessation and reduction rate during 3 months of active nicotine replacement therapy (NRT) and a follow-up period of 3 months in smoking hospital physicians and staff who are motivated to quit
- Trial name
- NCT00749463
- Testing
- Nicotine Gum, Nicotine Patch
- Where
- 6 sites in China
- Volunteers
- 300 people
- Sponsor
- McNeil AB
Nicotine Dependence, Tobacco Use
Puff Topography and Sensory Effects Across IQOS Device Generations
The goal of this clinical trial is to learn how people use two generations of IQOS heated tobacco devices and how each device affects their smoking behavior and sensory experience.
- Trial name
- NCT07712887
- Testing
- IQOS Iluma i with TEREA Tobacco Sticks, IQOS 2.4 with HEETS Tobacco Sticks
- Where
- 2 sites in Lebanon
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Psychiatric Disorders
TORCH - Transdiagnostic Observation of Risk Factors, Craving and Health Behaviours in Psychiatric Patients
Mental disorders are often accompanied by health-risk behaviours, psychiatric comorbidity, and reduced functioning. TORCH investigates transdiagnostic mechanisms underlying multiple health behaviour change in adult psychiatric…
- Trial name
- TORCH (NCT07844798)
- Testing
- person-centred interventions
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Nicotine Dependence, Vaping
Influence of the Consumption of Conventional and Electric Cigarettes on Skin Circulation
The survey participants are divided into a smoking and non-smoking group. The smoker group is further divided according to the quantity and quality of nicotine ("normal" smoking, vaping).
- Conditions
- Nicotine Dependence, Vaping, Smoking
- Trial name
- NCT04645914
- Testing
- Use of nicotine product (smoking/vaping)
- Where
- Germany
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Tobacco Use Disorder
Combination Pharmacotherapy for Smoking Cessation Among Methadone Patients
The purpose of this pilot study is to examine the effects of combined pharmacotherapy (Zyban/NRT)/behavioral treatment on smoking cessation among methadone maintenance therapy patients.
- Trial name
- NCT00060814
- Testing
- Combined intervention
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Nicotine Dependence
Extinction Based Treatment for Nicotine Dependence
The purpose of this study is to test two quit smoking therapies and to study brain function while each therapy is being used. You will be randomly assigned (like flipping a coin) to one of the two groups.
- Trial name
- Extinction01 (NCT00831155)
- Testing
- Nicotine Patches, Denicotinized Cigarettes
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Duke University
Tobacco Use Disorder, Smoking
Electronic Cigarettes (E-cigarettes) as a Harm Reduction Strategy
The purpose of this study is to examine the feasibility of using e-cigarettes as a method for harm reduction and the effects of providing e-cigarettes (or placebo e-cigarettes) on smoking outcomes.
- Trial name
- NCT02628964
- Testing
- e-cigarettes
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Bladder Cancer, Cervical Cancer
Zinc Supplements in Lowering Cadmium Levels in Smokers
RATIONALE: Zinc supplements may lower cadmium levels in smokers and may help prevent DNA damage. PURPOSE: This clinical trial is studying how well zinc supplements work in lowering cadmium levels in smokers.
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00376987
- Testing
- zinc oxide
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Wake Forest University Health Sciences
Tobacco Use Disorder
Smoking Termination Opportunity for inPatients
The Smoking Termination Opportunity for inPatients, (STOP) project is designed to capture the opportunity that is provided by admission for acute smoking related illness, to assist patients through withdrawal by use of a…
- Trial name
- STOP (NCT01141855)
- Testing
- Champix, Counselling alone
- Where
- 3 sites in Australia
- Volunteers
- 392 people
- Sponsor
- The Queen Elizabeth Hospital
Nicotine Dependence, Nicotine Use Disorder
Combined Pharmaco/Behavior Therapy in Adolescent Smokers
In the current proposal, we intend to study the efficacy of bupropion SR with or without combined contingency management (CM) among adolescent cigarette smokers.
- Trial name
- NCT00330187
- Testing
- Bupropion SR, Contingency Management
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Use Disorder
Evaluation of a Combined Parent-student Programme for Smoking Prevention in Berlin Schools
The purpose of this study is to evaluate the effectiveness of a combined parent-student program for smoking prevention in 7th graders in Berlin schools.
- Trial name
- BEST (NCT01306552)
- Testing
- Student-Intervention only group, Multi-component Intervention, Control Group
- Where
- Germany
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
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