Clinical trials: Acalculous Cholecystitis
Cholecystectomy, Laparoscopic
Clinical Study of Single Incision Laparoscopic Cholecystectomy in the Treatment of Patients With Acute Cholecystitis
Gallstone is a common disease in China.At present, the prevalence of gallstones in China is 15 %, and about 210 million people are sick.
- Trial name
- NCT06074679
- Testing
- Open cholecystectomy
- Where
- 5 sites in China
- Volunteers
- 600 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Cholecystitits
The Role of Antibiotic Treatment in Patients With Acute Mild Cholecystitis - A Prospective Randomized Controlled Trial
The treatment of acute cholecystitis includes limited oral intake, antibiotics and early or delayed surgery. To date there are no randomized trials proving the benefit of antibiotic treatment.
- Trial name
- NCT00557453
- Testing
- Antibiotic treatment, No antibiotics
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Hadassah Medical Organization
Acute Cholecystitis, Chronic Cholecystitis
Evaluation of Closed-loop TIVA Propofol, Sufentanil and Ketamine Guided by BIS Monitor
The purpose of this study is to compare a closed-loop intravenous anesthetic using Bispectral Index as a feedback loop and a controller based on reinforcement learning to titrate dose and intravenous anesthetic that is manually…
- Trial name
- NCT01942356
- Testing
- TIVA - Hypotension, TIVA - Hypertension, TIVA - Bradycardia
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Cholecystitis/Cholelithiasis
NIR Fluorescence Cholangiography With Low Dose of ICG
The objective of this clinical trial is to visualize the bile ducts by injecting a contrast that is only visible with infrared light. For this, we administrate an intravenous low dose of ICG before a cholecystectomy.
- Trial name
- NCT04005898
- Testing
- Near-infrared fluorescence cholangiography
- Volunteers
- 80 people
- Sponsor
- Hospital Son Espases
Cholecystitis, Cholelithiasis
Use of Robotics for Cholecystectomy; Retrospective Review of Outcomes, Set Up and Learning Curves
Comparing the use of surgical robotics during a Cholecystectomy, comparing different platforms and approaches (multi port verses single port).
- Trial name
- NCT03059745
- Testing
- Cholecystectomy
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of California, Davis
Cholecystitis
Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia
Many anesthesiologists use the Remifentanil for reducing a surgical pain and stabilizing a vital sign. However, this drug induce postoperative hyperalgesia.
- Trial name
- NCT02493231
- Testing
- Nefopam, Ketamine, Saline
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Gallbladder Diseases, Cholecystitis, Acute
Endoscopic vs Non-endoscopic Drainage for Benign Gallbladder Diseases in High-risk Patients or Patients Desiring Gallbladder Preservation
Common gallbladder conditions like gallstones, polyps, and gallbladder inflammation are typically treated by surgically removing the gallbladder.
- Conditions
- Gallbladder Diseases, Cholecystitis, Acute, Cholelithiasis
- Trial name
- GB-PRESERVE (NCT07649811)
- Testing
- Endoscopic Gallbladder Drainage, Percutaneous Gallbladder Drainage
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Air Force Military Medical University, China
Gall Stone, Gall Stones, Common Bile Duct
Influence of Gut Microbiome in Gallstone Disease
The goal of this prospective observational study is to explore the role of the gut microbiome in patients with gallstone disease.
- Conditions
- Gall Stone, Gall Stones, Common Bile Duct, Pancreatitis, Acute Cholecystitis
- Trial name
- NCT05732480
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Recurrent Cholecystitis, Cholecystitis
One vs. Two Stents for Gallbladder Disease
This randomized trial will look at whether placing two cystic duct stents is more effective than one cystic duct stent in preventing recurrent gallbladder disease (cholecystitis, gallstone pancreatitis, or biliary colic) among…
- Conditions
- Recurrent Cholecystitis, Cholecystitis, Symptomatic Gallbladder Disease, Biliary Colic
- Trial name
- NCT07222527
- Testing
- ERCP with one stent placement, ERCP with two stent placement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Cholecystitis, Acute, Common Bile Duct Calculi
Endoscopic Nasogallbladder Drainage Versus Gallbladder Stenting Before Cholecystecomy
Early laparoscopic cholecystectomy is the current standard therapy for acute cholecystitis, but temporary decompression of the gallbladder (GB) through percutaneous or endoscopic route can be required to alleviate inflammatory…
- Trial name
- NCT02394327
- Testing
- 7-Fr Pigtail type naso-cholecystic drainage tube (Liguory nasal biliary drainage set; Wilson-Cook Medical, Salem, NC, USA), 7-Fr double pigtail plastic stent (Zimmon; Wilson-Cook Medical, Salem, NC, USA)
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Ajou University School of Medicine
Acute Cholecystitis
Short Term Outcomes of Acute Cholecystitis Managed at a University Hospital
The aim of this retrospective study was to assess the different outcomes of early (performed on the patient's first admission for acute cholecystitis) and delayed cholecystectomy (done on a second admission) at King Abdulaziz…
- Trial name
- NCT03853408
- Testing
- Cholecystectomy
- Where
- Saudi Arabia
- Volunteers
- 88 people
- Sponsor
- King Abdulaziz University
Acute Calculous Cholecystitiis (ACC)
INtraoperative Approach With Eventual Clearance of Common bilE Duct by SpyGlass Discover vs Sequential Strategy in Patients With Acute Calculus Cholecystitis and Intermediate/High Risk of Common BiLE Duct Stone
INACCESSIBLE trial is a randomized controlled study that compares two different strategies for the treatment of Acute Calculous Cholecystitiis (ACC) patients with high/intermediate risk of CBDS, according to the score by Khoury T…
- Trial name
- INACCESSIBLE (NCT06918626)
- Testing
- ELC + Spyglass cholangiography, ERCP + Early Laparoscopic cholecystectomy (ELC) in two stage procedures
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Cholecystitis
Laparoscopic Cholecystectomy:
Various modifications have been tried in laparoscopic cholecystectomy since its introduction. One, two and three port LC have been performed on limited scale.
- Trial name
- NCT04107909
- Testing
- laparoscopic cholecystectomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Acute Cholecystitis
Magnetic Resonance Cholangiography and Intraoperative Cholangiography in Acute Cholecystitis
The treatment of choice for acute cholecystitis is cholecystectomy performed as soon as possible after onset of symptoms. Up to 9-22% of patients undergoing cholecystectomy due to cholecystitis have common bile duct stones.
- Trial name
- NCT04059601
- Testing
- Magnetic resonance cholangiography, Intraoperative cholangiography
- Where
- Finland
- Volunteers
- 180 people
- Sponsor
- Jyväskylä Central Hospital
Subtotal Cholecystectomy, Complicated Acute Cholecystitis
Subtotal Cholecystectomy for Complicated Acute Cholecystitis: a Multicenter Prospective Observational Study
We believe that subtotal cholecystectomy is a safe alternative to total cholecystectomy when the complicated gallbladder is encountered, resulting in decreased or equivalent risk of bile duct injury, major vascular injury…
- Trial name
- NCT04181801
- Testing
- Subtotal cholecystectomy
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Methodist Health System
Cholecystitis, Acute
AXIOS™ for Gallbladder Drainage as an Alternative to Percutaneous Drainage IDE
To evaluate the safety and effectiveness of the AXIOS™ Stent with Electrocautery Enhanced Delivery System in the management of symptoms of acute cholecystitis as an alternative to percutaneous gallbladder drainage.
- Trial name
- NCT03767881
- Testing
- AXIOS(TM) Stent and Electrocautery Enhanced Delivery System
- Where
- 7 sites in United States, Belgium
- Volunteers
- 30 people
- Sponsor
- Boston Scientific Corporation
Acute Cholecystitis
Endoscopic Ultrasonography (EUS) Guided Gallbladder Drainage With Two Months Stent Removal for Acute Cholecystitis: a Prospective Study
Acute cholecystitis (AC) is defined as an acute inflammatory disease of the gallbladder consequently to the presence of sludge or stones. AC accounts for 3-10% of all cases of abdominal pain.
- Trial name
- AC LAMS (NCT05272007)
- Testing
- EUS-biliary drainage
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Clinico Humanitas Mater Domini
Cholecystitis, Choledocholithiasis
Laryngeal Mask Airway Supreme Versus the Tracheal Tube as an Airway Device in Elective Laparoscopic Cholecystectomy
We hypothesise that the use of the LMA-Supreme provides greater ease of insertion and reduced haemodynamic variability during insertion compared to the tracheal tube, whilst still maintaining a patent airway to facilitate…
- Trial name
- NCT02037958
- Testing
- Laryngeal Mask Airway-Supreme, Endotracheal Tube
- Where
- Singapore
- Volunteers
- 76 people
- Sponsor
- Changi General Hospital
Acute Cholecystitis
Functional MRC With Eovist for Acute Cholecystitis
Functional magnetic resonance cholangiography (fMRC) with gadoxetate disodium (Eovist) is an accurate method of diagnosing acute cholecystitis.
- Trial name
- MRC (NCT02100358)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, Davis
Cholecystitis, Liver Neoplasms
Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating Room
This study aims to evaluate the feasibility and accuracy of a non-contact, camera-based physiological monitoring technology in a perioperative setting (including anesthesia induction, surgery, and recovery).Conventional vital…
- Conditions
- Cholecystitis, Liver Neoplasms, Cholelithiasis, Inguinal Hernia
- Trial name
- IBPM (NCT07473687)
- Testing
- Non-contact rPPG software
- Where
- Taiwan
- Volunteers
- 315 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan