Clinical trials: Acceptance
PreDiabetes, Obesity
Tolerability, Acceptance, and Utility of Intermittent CGM Use in Youth With Prediabetes
We are evaluating whether intermittent use of continuous glucose monitors (CGMs) in addition to standard nutritional counseling and physical activity counseling is associated with improved metabolic health for youth with…
- Conditions
- PreDiabetes, Obesity, Insulin Resistance
- Trial name
- NCT05505565
- Testing
- Abbott Freestyle Libre 2, Standard physical activity and nutritional counseling for prediabetes management
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Alabama at Birmingham
Sleep Apnea, Obstructive, Stroke
Stroke and CPAP Outcome Study 2
Obstructive sleep apnea (OSA) is associated with impaired stroke recovery. Treatment with continuous positive airway pressure (CPAP) may prevent this but is limited by poor adherence.
- Conditions
- Sleep Apnea, Obstructive, Stroke, Patient Adherence
- Trial name
- SCOUTS2 (NCT02809430)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Washington
Substance Use Disorders, Mental Health Impairment
Homeless Care Management App
There is a significant revolving door of incarceration among homeless adults, a population with substantial health disparities. Homeless adults who receive the professional coordination of individualized care (i.e., case…
- Conditions
- Substance Use Disorders, Mental Health Impairment, Health Behavior, Adherence, Patient
- Trial name
- Link2Care (NCT03399500)
- Testing
- In-Person Case Management at Homeless Recovery Program, Unlimited Smartphone, Smartphone Based Case Management (SPCM) app
- Where
- 2 sites in United States
- Volunteers
- 403 people
- Sponsor
- University of Oklahoma
Schizophrenia, Schizoaffective Disorder
A Trial to Explore Acceptance and Performance of Using a Digital Medicine System With Healthcare Professionals and Adults With Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis on an Oral Atypical Antipsychotic
Digital medicine systems (DMS) have been designed to assist individuals with the management of their daily health, wellness, and medication use.
- Conditions
- Schizophrenia, Schizoaffective Disorder, First Episode Psychosis
- Trial name
- NCT03568500
- Testing
- Digital Medicine System, Aripiprazole, Olanzapine
- Where
- 5 sites in United Kingdom
- Volunteers
- 44 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Epilepsy
Epilepsy Adherence in Children and Technology (eACT)
Fifty-eight percent of children with new-onset epilepsy do not take their antiepileptic drugs (AEDs) as prescribed, which is associated with continued seizures, mortality, poor quality of life, and high healthcare costs.
- Trial name
- eACT (NCT03817229)
- Testing
- Education microlearning sessions, Automated digital reminders, Problem-solving mHealth module
- Where
- 4 sites in United States
- Volunteers
- 268 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Atrial Fibrillation, Patient Engagement
Data-driven SDM to Reduce Symptom Burden in AF
This study is a single-group feasibility study evaluating decision aid visualizations which display common post-ablation symptom patterns as a tool for shared decision-making.
- Trial name
- NCT04993807
- Testing
- Shared decision-making tool
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Columbia University
Stroke, Health Care Acceptability
Telehealth After Stroke Care: Integrated Multidisciplinary Access to Post-stroke Care
The Telehealth After Stroke Care (TASC) trial is a pilot randomized controlled trial. It aims to evaluate the feasibility of a telehealth based model providing multidisciplinary access including nursing, pharmacy and physician…
- Conditions
- Stroke, Health Care Acceptability, Hypertension
- Trial name
- TASC (NCT04640519)
- Testing
- Usual care, TASC intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Diabetes Mellitus, Cardiovascular Disease
Promoting Adherence to Improve Effectiveness of Cardiovascular Disease Therapies
The purpose of this randomized clinical trial is to determine whether two low-intensity, technology based interventions, when compared to each other and to usual care, improve adherence to selected medications that are used to…
- Trial name
- PATIENT (NCT01251757)
- Testing
- Interactive Voice Recognition (IVR) phone calls, Educational mailings and follow-up for nonadherence
- Where
- 3 sites in United States
- Volunteers
- 21,752 people
- Sponsor
- Kaiser Permanente
Depression
Bright Start Study
The Bright Start study is a randomized trial to compare three approaches, or "arms", for delivering Bright Light Therapy (BLT) to real-world patients.
- Trial name
- NCT05356130
- Testing
- Written Educational Material on BLT, Enhanced BLT Encouragement and Adherence Promotion
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Kaiser Permanente
Asthma in Children, Medication Adherence
Financial Incentives to Improve Asthma
The aim of this pilot randomised controlled trial is to assess the effectiveness of a short-term financial incentives intervention at bringing about behaviour change, namely short-medium term improvements in inhaled…
- Trial name
- FINA (NCT05322044)
- Testing
- Financial incentives
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Imperial College London
COVID-19 Vaccination
Developing and Testing a COVID-19 Vaccination Acceptance Intervention
The COVID-19 pandemic has resulted in significant loss of life and suffering with total case and death counts increasing daily, particularly with the emergence of the delta variant.
- Trial name
- CoVAcS (NCT05027464)
- Testing
- Moving to COVID-19 Vaccine Acceptance Intervention
- Where
- 2 sites in United States
- Volunteers
- 338,718 people
- Sponsor
- VA Office of Research and Development
HIV/AIDS, Medication Adherence
Measuring and Monitoring Adherence to ART With Pill Ingestible Sensor System
Introduction of antiretroviral therapy (ART) has transformed HIV-infection from a fatal to manageable disease but adherence to ART remains critical to optimize outcomes.
- Trial name
- NCT02797262
- Testing
- Proteus digital health feedback (PDHF) system
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of California, Los Angeles
Insurance Status/Stability
IMPACCT for Kids' Care
Health insurance is important for children. Public insurance programs are available to many children, but some families report being confused about how to get and keep this insurance.
- Trial name
- IMPACCT (NCT02298361)
- Testing
- Health insurance outreach IT tools
- Volunteers
- 27,251 people, healthy volunteers welcome
- Sponsor
- OCHIN, Inc.
Osteoarthritis, Knee, Hypertension
Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension
The purpose of the Staying Active with Arthritis (STAR) research study is to determine if a 6-month program will improve leg exercise, fitness walking, and clinical outcomes (function, blood pressure, leg strength, pain, fatigue…
- Trial name
- STAR (NCT01280903)
- Testing
- STAR Intervention, Attention-Control
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- University of Pittsburgh
Stroke, Medication Adherence
Adherence to Medical Treatments for Telemedicine Patients
This study will test the feasibility of MedRem, a novel medication reminder and tracking system on wearable wrist devices, specifically with the Apple Watch 4.
- Trial name
- NCT04180475
- Testing
- MedRem application
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Medication Adherence, Kidney Transplantation
Improving Adherence in Nonadherent Kidney Transplant Patients
Organs for transplantation remain a scarce and precious resource with over 5000 patients currently on the kidney transplant waiting list.
- Trial name
- NCT03892317
- Testing
- Pharmacist led medication adherence interventions
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Imperial College London
Patient Adherence
Evaluation of a mHealth Intervention to Increase Adherence to Triage of Self-collected HPV+ Women (ATICA Project)
Background: Cervical cancer is one of the leading causes of cancer death among women worldwide, with more than 85% of cases occurring in low- and middle-income countries.
- Trial name
- ATICA (NCT03478397)
- Testing
- Multicomponent mHealth Intervention
- Where
- Argentina
- Volunteers
- 5,389 people
- Sponsor
- Centro de Estudio de Estado y Sociedad
Opioid-Related Disorders
Trial of Adherence App for Buprenorphine Treatment (TAAB) Study
The purpose of this study is to pilot test a smartphone application that allows video-based directly observed therapy for participants receiving buprenorphine treatment for opioid use disorder in office-based settings.
- Trial name
- NCT03779997
- Testing
- Video-based DOT Application
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- University of Washington
Skin Cancer
Evaluation of Adherence to Topical Agents: Applying Communication Technology to Improve Sunscreen Use
The purpose of this study is to determine if using an electronic reminder improves adherence to sunscreen use. The specific study aims are as follows: 1.
- Trial name
- NCT00535769
- Testing
- Electronic + no text message, Electronic monitor + text messages
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pain, Chronic Disease
Improving Chronic Pain Treatment in Primary Care
The primary objective of this study is to determine to what extent a collaborative intervention improves chronic pain-related outcomes in a VA primary care setting.
- Conditions
- Pain, Chronic Disease, Depression
- Trial name
- SEACAP (NCT00129480)
- Testing
- Assistance with Pain treatment
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- VA Office of Research and Development