Clinical trials: Access and Evaluation
Hemodialysis Access, Thrombosis
Hemodialysis Access Surveillance Evaluation Study
The purpose of the study is to learn if monitoring dialysis access blood flow during dialysis treatment with a transonic machine (an ultrasound technique) will prevent (or reduce) the development of dialysis access thrombosis…
- Trial name
- HASE (NCT02376361)
- Testing
- Transonic
- Where
- 3 sites in United States
- Volunteers
- 436 people
- Sponsor
- Albany Medical College
Psoriasis
A Canadian Open-Label Access Program to Evaluate Adalimumab When Added to Inadequate Therapy for the Treatment of Psoriasis
To evaluate the safety profile, the effectiveness and the economic impact of adalimumab when used for the treatment of subjects with active plaque psoriasis who have not adequately responded to prior psoriasis therapy.
- Trial name
- PRIDE (NCT00513370)
- Testing
- Humira (adalimumab)
- Where
- 27 sites in Canada
- Volunteers
- 203 people
- Sponsor
- Abbott
Renal Insufficiency
Clinical Study of POSS-PCU Vascular Grafts for Vascular Access
This study evaluates the safety and performance of a new vascular graft made of POSS-PCU as a vascular access conduit for haemodialysis.
- Trial name
- NCT02301312
- Testing
- POSS-PCU vascular graft
- Volunteers
- 30 people
- Sponsor
- University College, London
Congenital Muscular Dystrophy Due to Lamin A/C Mutation
HBCMD01- Expanded Access for the Treatment of Congenital Muscular Dystrophy.
This individual patient expanded access IND is requested for a patient diagnosed with LMNA-related congenital muscular dystrophy (L-CMD).
- Trial name
- NCT05154851
- Testing
- HB-adMSCs
- Where
- United States
- Sponsor
- Hope Biosciences Research Foundation
Kidney Failure, Chronic, Arteriovenous Fistulae
Preoperative Arteriovenous Fistula Simulation Study (ShuntSimulationStudy)
Patients suffering from end-stage renal disease (ESRD) are dependent on renal replacement therapy (dialysis). The majority of dialysis is facilitated by hemodialysis.
- Trial name
- 3S (NCT02453412)
- Testing
- AVF-simulation
- Where
- 9 sites in Netherlands
- Volunteers
- 236 people
- Sponsor
- Maastricht University Medical Center
Rheumatoid Arthritis
A Study to Evaluate Patient Characteristics and Treatment Patterns Among Rheumatoid Arthritis Patients
This is a retrospective cohort study to evaluate patient characteristics, treatment patterns including a 6-factor effectiveness proxy measure, health care resource use and associated costs among Rheumatoid Arthritis patients…
- Trial name
- NCT04047121
- Where
- United States
- Volunteers
- 1,349 people
- Sponsor
- Pfizer
Primary Health Care, Telemedicine
Proactive Telemedicine to Improve Healthcare Access and Prevention in Rural Primary Care (PTM)
The study evaluates whether Proactive Telemedicine (PTM) can improve healthcare access for individuals who have not contacted their primary care team for at least one year, compared with face-to-face visits.
- Conditions
- Primary Health Care, Telemedicine, Face to Face Consultation, Health Care Access
- Trial name
- PTM (NCT07299201)
- Testing
- Telemedicine Brief Behavioural Lifestyle Intervention, Face to face Brief Behavioural Lifestyle Intervention
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Open Surgery, Lymphedema
A Global, Prospective, Real-World, Investigation of the Symani® Surgical System for Microsurgical Anastomosis
The objective of this clinical study is to evaluate the Symani System's safety and effectiveness for microsurgical anastomosis during free tissue transfer surgery and lymphatic surgery.
- Conditions
- Open Surgery, Lymphedema, Free Tissue Transfer, Microsurgery
- Trial name
- PRIME (NCT06628219)
- Testing
- Symani Surgical System
- Sponsor
- MMI (Medical Microinstruments, Inc.)
Diabetes Mellitus (DM)
Post ACA Reform: Evaluation of Community Health Center Care of Diabetes
This innovative and timely study will measure the impact of Affordable Care Act (ACA) Medicaid expansions on diabetes mellitus (DM) prevention, treatment, expenditures and health outcomes.
- Trial name
- PREVENTD (NCT02685384)
- Testing
- Medicaid Expansion
- Volunteers
- 1,938,375 people
- Sponsor
- Oregon Health and Science University
Deafness
First Clinical Evaluation of HEARO Robotic Cochlear Implantation Surgery in Austria
To demonstrate the efficacy of a minimally invasive direct cochlear access via the HEARO procedure in cochlear implantation.
- Trial name
- HEARO-AT (NCT04795986)
- Testing
- HEARO Procedure
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Vienna
Heart Failure, Congestive
PARTNERS HF: Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With Heart Failure
The purpose of this study is to determine the value of diagnostic data obtained from Medtronic implantable cardioverter defibrillators (ICDs) with cardiac resynchronization therapy (CRT) to evaluate cardiovascular and heart…
- Trial name
- NCT00279955
- Testing
- Cardiac Resynchronization Therapy Device
- Where
- 93 sites in United States
- Volunteers
- 1,024 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Serious Adverse Events, Patient Safety
Chemokeyp: A Feasibility Study for Realtime Safety Data-Capture for Potential Serious Adverse Drug Events
Chemokeyp is a feasibility study testing a secure ED-Oncology interface for patients receiving chemotherapy who may present to unscheduled care with possible treatment-related complications.
- Conditions
- Serious Adverse Events, Patient Safety, Pharmacovigilance, Oncology
- Trial name
- NCT07592234
- Where
- Ireland
- Volunteers
- 100 people
- Sponsor
- St Vincent's University Hospital, Ireland
Covid-19, Critical Illness
Understanding Community Considerations, Opinions, Values, Impacts, and Decisions for COVID-19
The novel coronavirus (COVID-19) is affecting the way many people live their lives, including seeking medical care and maintaining good self-care to keep healthy.
- Conditions
- Covid-19, Critical Illness, Attitude of Health Personnel, Attitude to Health
- Trial name
- UC-COVID (NCT04373135)
- Testing
- Brief educational video
- Where
- United States
- Volunteers
- 1,971 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Brain Injury, Craniocerebral Trauma
PariS -TBI Study: Paris Severe Traumatic Brain Injury Study - 8 Years
The objective of the protocol is to pursue the long-term follow-up of a large cohort of severe traumatic brain injury patients. This outcome is to be described in terms of activity, participation, quality of life…
- Conditions
- Brain Injury, Craniocerebral Trauma, Trauma, Nervous System
- Trial name
- TCS8 (NCT02050633)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Evaluation of a National Health Information Technology-based Program to Improve Healthcare Coordination and Access to Information
Evaluation of the Health Digital Territories Program in the Five Pilot Territories (EvaTSN Project )
The aim is to evaluate a national health information technology-based program to improve healthcare coordination and access to information.
- Trial name
- EvaTSN (NCT02837406)
- Where
- 5 sites in France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Pregnancy
Michigan Contraceptive Access, Research, and Evaluation Study Children: Phase 1
This project builds on the Michigan Contraceptive Access Research and Evaluation Study (M-CARES) to evaluate the long-term effects of mothers' access to free contraceptives and reductions in unintended pregnancies on their…
- Trial name
- M-CARES-K (NCT04371900)
- Testing
- Mother receives voucher valued at 100% of cost of name-brand IUD (March 4, 2019-March 31, 2023), Mother receives voucher valued at 50% of cost of name-brand IUD (August 26, 2018-March 3, 2019)
- Where
- 9 sites in United States
- Volunteers
- 4,700 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Liver Transplant
OCS Liver PROTECT Continued Access Protocol
Continued Access Protocol to evaluate the effectiveness of the OCS Liver System to preserve and assess donor livers.
- Trial name
- NCT04186221
- Testing
- OCS Liver System
- Where
- 17 sites in United States
- Volunteers
- 74 people
- Sponsor
- TransMedics
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasm
- Trial name
- PICSI-H (NCT04281784)
- Testing
- EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 2,512 people
- Sponsor
- University of Washington
Lower Limb Amputation
Protocole Access-Socket
Lower limb amputation has a definitive impact on a person's locomotor abilities, considerably reducing his or her autonomy in everyday life. 50% of lower limb amputees in France are trans-femoral.
- Trial name
- NCT05224232
- Testing
- Access Socket, Rigid socket
- Where
- 4 sites in France
- Volunteers
- 17 people
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
End-stage Renal Disease
Propaten Randomized Investigation on Cost-benefit and Efficacy
The purpose for this study is to evaluate the patency and outcomes of conventional and heparin anticoagulant bonded arteriovenous grafts in patients with end stage renal disease.
- Trial name
- PRICE (NCT01601873)
- Testing
- PROPATEN, Standard Graft
- Where
- 5 sites in United States
- Volunteers
- 103 people
- Sponsor
- The University of Texas Health Science Center, Houston