Clinical trials: Accident
Stroke, CVA (Cerebrovascular Accident)
Translation And Psychometric Testing Of The Turkish Version Of Fugl-Meyer Assessment
The aim of this methodological study is to adapt the Fugl-Meyer assessment to Turkish culture and to test its validity and reliability in acute phase stroke patients.
- Conditions
- Stroke, CVA (Cerebrovascular Accident), Hemiplegia and/or Hemiparesis Following Stroke
- Trial name
- FMA-TR (NCT05823298)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa
Ischemic Stroke
SITS (Safe Implementation of Treatments in Stroke) Open Artery by Thrombectomy in Acute Occlusive Stroke Study
Ischemic stroke, i.e. irreversible damage of a part of the patient's brain, is caused by the formation of blood clot in the major vessel which gives blood supply to a certain part of the brain.
- Trial name
- SITS Open (NCT02326428)
- Testing
- Stent retriever endovascular device for thrombectomy, Intravenous thrombolysis by alteplase (Actilyse) (optional)
- Where
- Sweden
- Volunteers
- 341 people
- Sponsor
- Karolinska Institutet
Occult Bleeding, Hemorrhage
Trauma Study: Early Warning of Progression Toward Hemodynamic Deterioration After Trauma
This study is Phase 3 of a three-phase DOD CDMRP funded project for the development of a multi-technology poly-anatomic noninvasive system for early detection of occult hemorrhage.
- Trial name
- NCT04912232
- Testing
- Detection of Occult Hemorrhage in Trauma Patients
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Acquired Brain Injury, Stroke/ Cerebrovascular Accident (Ischemic or Hemorrhagic)
Regulating Emotions and Behaviors After Brain Injury
After acquired brain injury (ABI), persons can experience emotional and behavioral difficulties, that can be painful both for the person and his/her family.
- Conditions
- Acquired Brain Injury, Stroke/ Cerebrovascular Accident (Ischemic or Hemorrhagic), Brain Tumor (After Recovery), Encephalitis
- Trial name
- GREMO-LCA (NCT05393492)
- Testing
- Dialectical Behavior Therapy and Radically Open dialectical behavior therapy
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Automobile Driving
Driving Simulator Performance After Intake of Zopiclone Sleeping Pills
Zopiclone, a widely used hypnotic drug, is frequently found in blood samples taken from drivers suspected of driving under the influence.
- Trial name
- NCT01257165
- Testing
- Zopiclone, Ethanol
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Trauma Injury, Trauma
The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma
Traumatic injury followed by critical illness provokes pathophysiologic changes in the bone marrow and the gut that contribute to persistent anemia and changes in the microbiome which significantly impact long-term recovery.
- Conditions
- Trauma Injury, Trauma, Critical Illness, Microbiome
- Trial name
- NCT06606119
- Testing
- Data and tissue collection
- Where
- 3 sites in United States
- Volunteers
- 275 people
- Sponsor
- University of Florida
Cervical Injury Spine
Treatment of Patients With Neck Pain After a Commuting Accident
Introduction. Neck pain is one of the main causes of incapacity for work. The economic impact of neck pain is considerable due to the cost of medical treatment and physiotherapy.
- Trial name
- NCT06938828
- Testing
- Observational cohort group
- Where
- Spain
- Volunteers
- 204 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Cardiovascular Diseases, Heart Failure, Congestive
Evaluating the Relationship Between Fatty Acids and Heart Disease
Cardiovascular disease (CVD) affects millions of people in the United States; each year, more people die from CVD than from any other disease.
- Conditions
- Cardiovascular Diseases, Heart Failure, Congestive, Atrial Fibrillation, Cerebrovascular Accident
- Trial name
- NCT00404872
- Where
- 4 sites in United States
- Volunteers
- 4,766 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cerebrovascular Accident
A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GSK1358820 (Botulinum Toxin Type A) in Chinese Subjects With Post-stroke Upper Limb Spasticity
This trial is a multicenter, double-blind, randomized, placebo-controlled study to compare GSK1358820 (Botulinum Toxin Type A, also known as "OnabotulinumtoxinA" or "Botox") with placebo on the efficacy and safety of treatment in…
- Trial name
- NCT01153815
- Testing
- GSK1358820(Botulinum toxin type A)
- Where
- 13 sites in China
- Volunteers
- 170 people
- Sponsor
- GlaxoSmithKline
Medication Adherence, Accidental Overdose
Blister Packaging Medication to Increase Treatment Adherence and Clinical Response
This quantitative, interview-based study will determine if increased prescription medication adherence via blister pack administration will reduce suicide related behavior among the high risk population of patients discharged…
- Conditions
- Medication Adherence, Accidental Overdose, Deliberate Overdose, Suicide, Attempted
- Trial name
- BP (NCT01118208)
- Testing
- Blister packaging medications, Dispense as usual
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- VA Eastern Colorado Health Care System
Stroke, Ischemic
Validation of TriAGE+ for Predicting Stroke Risk in ED Patients Presenting With Dizziness
Ischemic cerebrovascular diseases originating from the brain's posterior circulation account for 20-25% of cases. Among patients diagnosed with cerebellar infarction, 10% present with isolated dizziness as their sole symptom.
- Trial name
- NCT06641050
- Testing
- TRIAGE+ score assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 818 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Accidental Awareness During General Anesthesia
Comparison of Modulations of Motor Brain Activity and SedLine After Median Nerve Stimulation in General Anesthesia
To this date, no monitoring device can reliably detect episodes of accidental awakening during general anesthesia. One promising approach is the use of electroencephalography (EEG) to detect movement attempts via a brain-computer…
- Trial name
- NCT07267403
- Testing
- EEG Headset, SD LTM STIM (Micromed), SedLine®
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Brugmann University Hospital
Stroke, Cerebrovascular Accident
Sensory-driven Motor Recovery in Poorly Recovered Subacute Stroke Patients
This research project addresses a scientifically important question that cannot be answered by other means. The use of peripheral nerve stimulation has the potential to enhance recovery in subacute stroke patients with poor…
- Trial name
- NCT03124186
- Testing
- S88 Dual Output Stimulator by Grass Technologies
- Volunteers
- 73 people
- Sponsor
- Lumy Sawaki
Fall, Fall Accident
The Geriatric Emergency Department Pharmacologic Harm Prevention Project
The goal of this project is to determine whether pharmacogenomic testing (using participants' DNA) can help optimize medication prescribing and reduce side effects in older adults taking five or more medications.
- Conditions
- Fall, Fall Accident, Poly Pharmacy, Adverse Drug Events
- Trial name
- GREAT PHARM (NCT07216846)
- Testing
- DNA care pathway
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Florida Atlantic University
Sepsis, Trauma Injury
Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis
Adverse outcomes in surgical sepsis patients are secondary to dysregulated emergency myelopoiesis, and expansion of myeloid-derived suppressor cells.
- Trial name
- NCT05110937
- Testing
- Blood sampling
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Florida
Post-traumatic Stress Disorders
A Simple Cognitive Task to Reduce the Build-Up of Flashbacks After a Road Traffic Accident
This research study is designed to investigate the effects of a simple cognitive task (a memory reactivation cue following by playing the computer game "Tetris") on flashbacks and other post-traumatic stress symptoms after a road…
- Trial name
- SCARTA (NCT02080351)
- Testing
- Simple cognitive task
- Where
- United Kingdom
- Volunteers
- 71 people
- Sponsor
- University of Oxford
Prosthetic Cardiac Valve Thrombosis, Cerebrovascular Accident
Rule Out Transcatheter Aortic Valve Thrombosis With Post Implantation Computed Tomography (RETORIC)
The RETORIC study is a prospective cohort study with a primary aim to assess the incidence and independent predictors of reduced leaflet motion and valve thrombosis after TAVI procedure using multimodality imaging strategy…
- Conditions
- Prosthetic Cardiac Valve Thrombosis, Cerebrovascular Accident, Prosthetic Valve Malfunction
- Trial name
- RETORIC (NCT02826200)
- Testing
- Acenocoumarol, Standard of care
- Where
- Hungary
- Volunteers
- 200 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Accidental Fall, Postural Instability
Effects of Otago Exercise Program Vs Blind Folded Exercise on Falls, Balance and Quality of Life in Geriatric Population.
As people age, maintaining balance can become more difficult, which increases the risk of dangerous falls. This clinical study aims to compare two different physical therapy programs to see which one is more effective at…
- Conditions
- Accidental Fall, Postural Instability, Balance Assessment
- Trial name
- NCT07797699
- Testing
- Otago Exercise Program (OEP), Blindfolded Exercise (BFE)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Ibadat International University, Islamabad
Cerebrovascular Accident, Stroke
Task-oriented Training for Stroke: Impact on Function Mobility
Residual neurological deficits from stroke lead to gait inefficiencies, resulting in an extremely high energy cost of movement and contributing to overall disability and lower quality of life.
- Trial name
- TOTS (NCT01322607)
- Testing
- High-intensity Treadmill Exercise, Low-intensity Lifestyle Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea
Residual Sleepiness and Accident Risk in Treated Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a major cause of excessive daytime sleepiness and impaired vigilance, leading to an increased risk of road and occupational accidents.
- Trial name
- CRASH (French) (NCT07545421)
- Testing
- Hypoxic burden computation, additional procedures and questionnaire
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
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