Clinical trials: Accidental Injuries
Osteoporosis
Secondary Prevention of Osteoporosis
The purpose of this study is to develop and implement an evidence based protocol for the secondary prevention of osteoporotic fractures and falls, and to determine how compliance with this intervention improves muscle strength…
- Trial name
- NCT00421343
- Testing
- alendronate with cholecalciferol, calcium carbonate with cholecalciferol, Falls prevention measures
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Hebrew SeniorLife
Burns, Smoke Inhalation Injury
Helping Children's Centres to Enhance Home Safety
Many children have accidents, some are very serious and they are a major cause of death in children aged 1-4 years. Many accidents are preventable This study aims to find out the best way to help Children's Centres to provide…
- Trial name
- NCT01452191
- Testing
- Injury Prevention Briefing Plus facilitation, Injury Prevention Briefing
- Where
- 4 sites in United Kingdom
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Alcohol Drinking, Alcohol Use Disorder
Effect of Theta Burst Stimulation on Alcohol Cue Reactivity
Alcohol Use Disorder (AUD) is prevalent, devastating, and difficult to treat. The intransigence of AUD is readily apparent in the Trauma Unit of Wake Forest University Baptist Hospital, wherein 23% of trauma related admissions…
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Trauma Injury, Alcohol Dependence
- Trial name
- NCT04223154
- Testing
- Real iTBS to the dlPFC
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Wake Forest University Health Sciences
Ischemic Stroke, Acute
MEXIDOL® in the Rehabilitation Treatment of Patients With Acute Cerebral Failure
The use of metabolic modulators creates prospects for increasing the efficiency of the rehabilitation treatment of patients with acute cerebral failure
- Trial name
- NCT06221826
- Testing
- Mexidol
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Pharmasoft
Accidental Falls
Characterizing Wheelchair-Related Falls in Elderly Veterans
The purpose of this study is to find out about the risk factors for wheelchair-related falls among elderly veterans, and to find out about the costs and consequences of those falls.
- Trial name
- NCT00363246
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 766 people
- Sponsor
- US Department of Veterans Affairs
Trauma/Injury Problem
Early Whole Blood in Patients Requiring Transfusion After Major Trauma
The proposal will assess if patients who require massive transfusion can be accurately predicted early after emergency department arrival and assess if the use of stored whole blood during initial resuscitation will reduce…
- Trial name
- NCT01227005
- Testing
- Transfusion of blood products
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- The University of Texas Health Science Center, Houston
Trauma Injury
ICG Fluorescence Imaging in Lower Extremity Amputation Patients
This is a non-randomized prospective study of 30 patients scheduled to undergo lower extremity amputation (below the knee, through the knee or above the knee) evaluating bone perfusion and viability using indocyanine green (ICG)…
- Trial name
- NCT04250558
- Testing
- Lower Extremity Amputation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Trauma Injury
Early Use of Cryoprecipitate With Major Hemorrhage Protocol (MHP) Activation
The purpose of this trial is to compare standard of care (SOC) massive transfusion protocol to SOC massive transfusion protocol plus early use of cryoprecipitate (within 90 minutes of emergency department arrival).
- Trial name
- NCT04704869
- Testing
- Cryoprecipitate, Red Blood Cells, Plasma
- Where
- 25 sites in United States, United Kingdom
- Volunteers
- 1,604 people
- Sponsor
- Bryan Cotton
Rib Fracture, Rib Fracture Multiple
Orthosis of Acute Traumatic Rib Fractures Via RibFx Belt for Pain Alleviation and Improved Pulmonary Function
Acute traumatic rib fractures are a common issue for patients of trauma surgeons. They inflict substantial morbidity, the most dreaded and consequential of which are pulmonary complications.
- Conditions
- Rib Fracture, Rib Fracture Multiple, Trauma, Trauma Chest
- Trial name
- RibFx (NCT03846024)
- Testing
- RibFx Orthosis Belt
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Vermont Medical Center
Pain, Acute, Anesthesia, Local
Perineural Local Anesthetic Administration With a Continuous Infusion Versus Automatic Intermittent Boluses
This will be a randomized comparison of continuous local anesthetic infusion with patient controlled boluses (PCA) to automated boluses with PCA for continuous popliteal sciatic nerve blocks.
- Conditions
- Pain, Acute, Anesthesia, Local, Trauma Injury
- Trial name
- NCT04458467
- Testing
- Continuous Infusion, Automated Intermittent Boluses
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of California, San Diego
Trauma Injury
ICG Fluorescence Imaging in Trauma Patients
This will be a prospective observational trial to better understand the range and variation associated with bone/soft tissue perfusion in fracture patients and examine the relationship between perfusion, measured using…
- Trial name
- NCT04245111
- Testing
- Immunofluorescence Imaging
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pain
Celecoxib Efficacy And Safety Versus Diclofenac In Acute Pain Due To Cervical Sprain Related To A Traffic Accident
This Study Will Evaluate Celecoxib Efficacy And Safety Versus Standard Doses Of Diclofenac In Acute Pain Due To Cervical Injury (Due To A Sprain) Related To A Motor Vehicle Accident
- Trial name
- NCT00894790
- Testing
- Celecoxib, oral Diclofenac
- Where
- 2 sites in Mexico
- Volunteers
- 8 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Arthritis, Rheumatoid Arthritis
Wright Foot & Ankle Post-Market Observational Study
WRIGHT FOOT \& ANKLE POST-MARKET OBSERVATIONAL STUDY, Multi-Year, Multi-Site, Multi-Device, Post-Market Observational Study, 10 sites, a minimum of 40 patients per device
- Conditions
- Arthritis, Rheumatoid Arthritis, Fracture, Trauma Injury
- Trial name
- NCT04118894
- Testing
- Foot and Ankle Devices
- Where
- 5 sites in United States, France and 2 more
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Stryker Trauma and Extremities
Vertebral Artery Dissection, Cerebrovascular Accident
Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain
The Investigators are performing a study to determine, in patients with chronic/recurrent neck pain, the cerebrovascular hemodynamic consequences of cervical spine movements, including manipulation, in vivo using fMRI technology…
- Conditions
- Vertebral Artery Dissection, Cerebrovascular Accident, Stroke
- Trial name
- NCT02667821
- Testing
- Head positions and spinal manipulation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Canadian Memorial Chiropractic College
Accidental Falls, Wounds and Injuries
Strategies to Reduce Injuries and Develop Confidence in Elders
The aim of this pragmatic cluster-randomized trial is to determine the effectiveness of an evidence-based, patient-centered multifactorial fall injury prevention strategy in community dwelling older adults at risk of falls…
- Trial name
- STRIDE (NCT02475850)
- Testing
- Evidence-based tailored fall prevention, Usual care
- Where
- 10 sites in United States
- Volunteers
- 5,451 people
- Sponsor
- Brigham and Women's Hospital
Pregnancy, Sexually Transmitted Infections
Teen Video Study to Reduce Risky Driving and Sexual Behavior in Adolescents
The purpose of this study is to measure the effects of an interactive video on adolescent risky behaviors and outcomes, with one video intended to reduce teen pregnancies and the other intended to reduce automobile accidents.
- Conditions
- Pregnancy, Sexually Transmitted Infections, Automobile Accidents
- Trial name
- TVS (NCT02049710)
- Testing
- Seventeen Days, Driving Skills for Life
- Where
- 3 sites in United States
- Volunteers
- 1,317 people
- Sponsor
- Carnegie Mellon University
Occult Bleeding, Hemorrhage
Trauma Study: Early Warning of Progression Toward Hemodynamic Deterioration After Trauma
This study is Phase 3 of a three-phase DOD CDMRP funded project for the development of a multi-technology poly-anatomic noninvasive system for early detection of occult hemorrhage.
- Trial name
- NCT04912232
- Testing
- Detection of Occult Hemorrhage in Trauma Patients
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Suicide, Accidental Injuries
Family Safety Net - Aim 3: Randomized Control Trial
Our parallel group clinical trial of the Family Safety Net (FSN) intervention addresses two main questions: Is the Family Safety Net (FSN) intervention feasible and acceptable in two formats: motivational interviewing (FSN MI)…
- Conditions
- Suicide, Accidental Injuries, Firearm Injury
- Trial name
- FSN (NCT05657119)
- Testing
- MI FSN - Lethal Means Reduction, Scripted FSN - Lethal Means Reduction, General Firearm Safety Intervention - General Firearm Safety
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Aging, Accidental Fall
Reducing CNS-Active Medications to Prevent Falls and Injuries in Older Adults
The overall objective of STOP-FALLS is to test whether a patient-centered deprescribing intervention that focuses on CNS-active medications reduces medically treated falls among older adults.
- Trial name
- STOP-FALLS (NCT05689554)
- Testing
- STOP Falls Educational Intervention
- Where
- United States
- Volunteers
- 2,367 people, healthy volunteers welcome
- Sponsor
- University of Washington
Diabetic Foot Ulcer, Pressure Ulcer
A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1
The study is a prospective, single arm, multicenter efficacy study, consisting of 60 subjects who will complete the study (note: if any patients are lost to follow-up or withdrawn, enrollment will increase to compensate for loss…
- Conditions
- Diabetic Foot Ulcer, Pressure Ulcer, Venous Leg Ulcer, Trauma Injury
- Trial name
- NCT04577183
- Testing
- RD1 System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- RedDress Ltd.