Clinical trials: Accidents Injury
Open Abdomen, Abdominal Adhesions
Seprafilm in Open Abdomens: a Study of Wound and Adhesion Characteristics in Trauma Damage Control Patients
The goal of this study is to test the effects of Seprafilm adhesion barrier on patients who are undergoing open abdomen damage control management for traumatic injuries when compared to no adhesion barrier use.
- Conditions
- Open Abdomen, Abdominal Adhesions, Trauma, Wounds and Injury
- Trial name
- OASIT (NCT01594385)
- Testing
- Seprafilm
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stan Stawicki
Decompression Sickness
Impact of Hyperoxia and Involvement of the Immune System in Diving Accident
The impact of oxygen therapy in many pathologies has been subject of recent work, arguing both favourable and harmful effects. Consequently, one can wonder about the influence of hyperoxic gas mixture during diving on the genesis…
- Trial name
- OXYDIVE (NCT04791488)
- Testing
- Hyperbaric oxygen therapy, Diving simulation
- Where
- France
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Trauma Injury, Haemorrhagic Shock
Prediction of Massive Transfusion in Trauma Patients
Since the 2000s, many prognostic scores were developed to predict traumatic haemorrhage. Most of these studies were retrospectives based on registers.
- Conditions
- Trauma Injury, Haemorrhagic Shock, Bleeding, Emergencies
- Trial name
- MTP (NCT04561050)
- Testing
- Comparison of score performances (Overall performance, discrimination and calibration)
- Where
- Switzerland
- Volunteers
- 13,222 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Blindness, Cerebrovascular Accident
Mechanisms of Human Plasticity in the Human System
The purpose of this study is to investigate the physiology associated with plasticity of the motor system. Plasticity refers to the process by which neighboring brain cells assume the responsibilities of damaged or diseased brain…
- Conditions
- Blindness, Cerebrovascular Accident, Spinal Cord Injury
- Trial name
- NCT00001661
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Shoulder Injuries and Disorders
Usability and Acceptance of a New Robotic Exoskeleton for Shoulder Rehabilitation
The purpose of this pilot study is to validate the safety, reliability and usability of FLOAT medical device, a prototypal robotic system for the rehabilitation of the shoulder, designed and developed in the Rehab Technologies…
- Trial name
- CRMINAIL08 (NCT04758520)
- Testing
- FLOAT upper limb exoskeleton
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Abdominal Trauma, Abdominal Injury
A Non-Traumatic Binder for Temporary Abdominal Wall Closure
At the end of most abdominal operations, the fascial layer is closed by stitching edges of the wound together. However, because of logistic and/or technical reasons or the patient's critical condition, the surgeon is forced to…
- Conditions
- Abdominal Trauma, Abdominal Injury, Abdominal Infection, Abdominal Sepsis
- Trial name
- ABRO (NCT03815370)
- Testing
- Experimental: ABRO™ Binder Arm
- Where
- 4 sites in Canada
- Volunteers
- 140 people
- Sponsor
- Unity Health Toronto
Head Injury Trauma
Treatment and Outcome of Patients With Mild Head Injury
The study aims to assess the incidence of complications, such as intracranial haemorrhages and neurological deficits, in patients with head trauma treated in the emergency departments of the Emilia-Romagna Region and to compare…
- Trial name
- BTER23 (NCT07339319)
- Where
- 4 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Fall Injury, Fall
Does Participation in a Fall Preparedness Program Improve Fall Efficacy Among Older Adults
The purpose of this study is to determine if a fall preparedness program can reduce the fear of falling in older adults and subsequently improve their function and reduce falls with injury.
- Conditions
- Fall Injury, Fall, Falls (Accidents) in Old Age
- Trial name
- NCT06545539
- Testing
- Fall Preparedness Exercise Class
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Youngstown State University
Trauma Injury, Trauma Blunt
Extremity Trauma At a Level 1 Trauma Center
Blunt vascular trauma to the lower extremity has been associated with injuries to the anteroposterior tibial arteries or popliteal artery in the form of transection, occlusion, or intimal injury.
- Conditions
- Trauma Injury, Trauma Blunt, Vascular Trauma
- Trial name
- NCT06402669
- Testing
- Packed Red Blood Cell Administration
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Arrowhead Regional Medical Center
Trauma Injury, Airway Control
LITES Task Order 0005 Prehospital Airway Control Trial (PACT)
The Prehospital Airway Control Trial (PACT) is a proposed 5 year, open label, multi-center, stepped-wedge randomized trial comparing airway management strategies of prehospital trauma patients.
- Trial name
- PACT (NCT04100564)
- Testing
- Supraglottic airway device, Standard airway management
- Where
- 14 sites in United States
- Volunteers
- 2,010 people
- Sponsor
- Jason Sperry
Trauma, Emergencies
Descriptive Study of Trampoline Accidents in the Pediatric Emergency Department of Rennes
The aim of this study is to compare trauma related to others sport to trauma due to trampoline in pediatric emergencies of Rennes.
- Conditions
- Trauma, Emergencies, Child, Only
- Trial name
- TRAUMPO (NCT03250936)
- Where
- France
- Volunteers
- 4,000 people
- Sponsor
- Rennes University Hospital
Trauma Injury
Using the GTOS to Stratify the Mortality Risk of Adult Trauma Patients
Trauma significantly impacts both short- and long-term health outcomes, resulting in substantial mortality. Early identification and risk stratification in trauma patients are crucial for timely medical interventions.
- Trial name
- NCT06475612
- Testing
- Death, Survival
- Where
- Taiwan
- Volunteers
- 40,068 people
- Sponsor
- Chang Gung Memorial Hospital
Closed-Loop Communication
COntrolled MAp Trauma Brain Injury (COMAT Study)
The goal of this randomized controlled trial will be to show that the use of a novel automated system to guide vasopressor administration in head trauma injury patients will results in more time spent with a mean arterial…
- Trial name
- COMAT (NCT03792581)
- Testing
- EV1000 and closed-loop system
- Where
- France
- Sponsor
- Erasme University Hospital
Virtual Reality, Musculoskeletal Pain
Virtual Reality Analgesia In Trauma Rehab
This will be a pilot study utilizing Virtual Reality Analgesia (VRA) as a first line nonpharmacologic analgesic intervention on the Acute Rehabilitation Unit.
- Conditions
- Virtual Reality, Musculoskeletal Pain, Opioid Use, Anxiety
- Trial name
- NCT03894592
- Testing
- Virtual reality
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Accidental Fall, Fall
Remote Monitoring and Analysis of Gait and Falls Within an Elderly Population
The investigators aim to do this initial pilot study as an observational prospective cohort study, evaluating elderly patients who have capacity in National Health Service (NHS) rehabilitation and community hospitals.
- Conditions
- Accidental Fall, Fall, Fall Injury, Hip Fractures
- Trial name
- 4279 (NCT03680014)
- Testing
- CUSH
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CUSH Health Ltd.
Motor Vehicle Accident, Burns
Dysfunctional Posttraumatic Cognitions in Children and Adolescents
The purpose of this study is to investigate the psychological consequences of motor vehicle accidents and burn accidents in 7-18 years old children and adolescents.
- Trial name
- PTC (NCT02693249)
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- University Children's Hospital, Zurich
Accidental Falls, Fractures
Exercise Intervention to Prevent Fall-related Fractures and Other Injuries : The Ossébo Study
1. Primary objective: to evaluate the effectiveness of a fall prevention exercise program in preventing falls resulting in fractures and other physical traumas. 2.
- Conditions
- Accidental Falls, Fractures, Fall-related Injuries
- Trial name
- Ossébo (NCT00545350)
- Testing
- Fall prevention exercise program
- Where
- 20 sites in France
- Volunteers
- 706 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Emergencies, Trauma Injury
Evaluation of the Course Format "NASIM25"
The investigators intend to evauate the development and professional safety of aspiring prehospital emergency pyhsicians in a cross sectional and longitudinal modality.
- Trial name
- NCT05295485
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Trauma, Trauma Injury
Deploying Emergency Bystander Internet Training
The primary aim of this study is to evaluate the efficacy of a massive open online course (MOOC) for training lay first responders in sub-Saharan Africa.
- Trial name
- DEBIT (NCT05909917)
- Testing
- Half-Day First Responder Training
- Where
- 4 sites in Kenya, Nigeria and 2 more
- Volunteers
- 658 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Trauma Injury, Trauma
OCT in Open Fracture and Infected Fracture
This is a pilot prospective, observational study of patients with open or infected fracture evaluating the feasibility and acceptability of OCT, a light-based imaging modality that requires no drug or contrast agent.
- Conditions
- Trauma Injury, Trauma, Open Fracture, Fracture Infection
- Trial name
- NCT05785182
- Testing
- Open Fracture, Infected Fracture
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dartmouth-Hitchcock Medical Center