Clinical trials: Accommodation Disorder, open to volunteers
Anabolic Steroid Overdose, Infertility
Prospective, Longitudinal Study on FItness DOping in DenmarK
The aim of this prospective longitudinal study is to investigate the risks associated with use of anabolic steroids in fitness circles in Denmark in order to assess the scope of therapeutic need existing as a consequence of use.
- Conditions
- Anabolic Steroid Overdose, Infertility, Cardiovascular Complication, Illicit Drug Use
- Trial name
- FIDO-DK/RH (NCT05599438)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Caroline Michaela Kistorp
Rizarthrosis
Comparative Study Between the Use of Trapeziometacarpal Prostheses and the Usual Resection-tenosuspension Arthroplasty for the Treatment of Rhizarthrosis, Focusing on Changes in Pain (Measured With the VAS Scale) and Function (With the Quick-DASH).
It is a randomized, prospective, single-blind study of two treatment techniques for rhizarthrosis. The patients are divided into two groups: one in which a Maia trapeziometacarpal prosthesis is implanted, and the other in which…
- Trial name
- NCT07101887
- Testing
- Implantation of thumb prosthesis, Burton-Pellegrini technique
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Parc de Salut Mar
Critical Illness
Mitochondrial Assessment in Critical Ill Patients in Intensive Care
Critically ill patients often require admission to the intensive care unit (ICU). When patients develop organ failures and end up on a ventilator, there are changes in the body's cell function that can increase the risk of poor…
- Trial name
- MitoICU (NCT07018843)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Geriatric Assessment, Adjuvant Drug Therapy
Aspects of Adjuvant CDK4/6 Inhibitors in Older Breast Cancer Patients - Focusing on Geriatric Screening
Older breast cancer patients should not be categorically excluded from adjuvant therapies, including the recommended CDK4/6 inhibitors (CDK4/6i) administered in combination with endocrine therapy.
- Conditions
- Geriatric Assessment, Adjuvant Drug Therapy, Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Trial name
- FUTURE (NCT07273357)
- Where
- 5 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Region Jönköping County
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
This phase I trial tests zanubrutinib in combination with sonrotoclax for treating underrepresented ethnic and racial minorities with B-cell non-Hodgkin lymphoma that has come back after a period of improvement (relapsed) or that…
- Conditions
- Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue
- Trial name
- NCT06859008
- Testing
- Biopsy, Biospecimen Collection, Bone Marrow Aspiration
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- City of Hope Medical Center
Refractive Errors, Cycloplegic Refraction
ML Models Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Myopic Adults
This study presents a machine learning model that predicts cycloplegic refraction in adults with myopia using standard non-cycloplegic eye measurements, aiming to reduce the need for cycloplegic drops while still identifying…
- Conditions
- Refractive Errors, Cycloplegic Refraction, Accommodation
- Trial name
- NCT07690813
- Testing
- Machine learning model for predicting cycloplegic refraction
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Shoulder Pain, Volleyball Players
Focusing the Shoulder or Considering the Whole-Body in Volleyball Physiotherapy
Shoulder pain can be common in overhead sports, and in particular, in volleyball. Different physiotherapy protocols can be adopted depending on the suspected pathophysiological mechanisms.
- Trial name
- FocusVolley (NCT07072091)
- Testing
- Total body physiotherapy, Focus shoulder physiotherapy, Education
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Hyperopia, Farsightedness
The Emmetropization Via Accommodation (EVA) - II Study
To determine if wearing a novel treatment during a 15-month period will enhance emmetropization in 4-month-old infants who have demonstrated poor ocular accommodation (eye focusing).
- Conditions
- Hyperopia, Farsightedness, Hypermetropia
- Trial name
- EVA-II (NCT07838597)
- Testing
- Experimental treatment arm
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Ohio State University
Healthy Young Adults, Accommodation Disorder
Study in Young Adults to Understand How Glasses With a Small Reading Addition Affect Focusing and Eye Coordination During Vision Tasks
This clinical study aims to understand how glasses with a small reading addition affect the way the eyes focus and work together in young adults with normal near vision.
- Trial name
- BIPBIP (NCT07859917)
- Testing
- Eye exam, Questionnaires, Washout lenses
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Essilor International
Obsessive-Compulsive Disorder
Project EMPOWER-OCD
This research study aims to adapt and evaluate the acceptability and effectiveness of Project EMPOWER-OCD for socioeconomically diverse caregivers of patients with OCD. Designed to reduce obstacles (e.g.
- Trial name
- NCT07158801
- Testing
- Project EMPOWER-OCD, Project CARE
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Interstitial Lung Disease, Comorbidities and Coexisting Conditions
Taiwan Interstitial Lung Disease Multi-center Investigation and Registry
The Taiwan Interstitial Lung Disease (ILD) Multi-center Investigation and Registry aims to evaluate the long-term outcomes of patients with fibrotic interstitial lung disease.
- Conditions
- Interstitial Lung Disease, Comorbidities and Coexisting Conditions, Pulmonary Arterial Hypertension, Treatment Adherence
- Trial name
- TAILI (NCT06476470)
- Where
- Taiwan
- Volunteers
- 10,000 people
- Sponsor
- Taichung Veterans General Hospital
Ankylosing Spondylitis (AS)
Integrated Traditional Chinese and Western Medicine for Ankylosing Spondylitis (AS): A Cohort Study Protocol Focusing on Spondyloarthritis Research Consortium of Canada (SPARCC) Scoring System
This study is a multicentre, ambidirectional, observational cohort study. The ambidirectional design incorporates both the collection of retrospective data from the three years prior to enrolment, and a prospective follow-up…
- Trial name
- NCT07509775
- Where
- China
- Volunteers
- 210 people
- Sponsor
- China-Japan Friendship Hospital
Multiple Myeloma
Analysis of the Resistance and Sensitivity Mechanisms to Teclistamab by Focusing on Single Immune Cell Examination
The aim of this study is to discover the immune and oncogenomic features that distinguish patients who respond to teclistamab from patients who are primarily resistant.
- Trial name
- ResisTec (NCT05945524)
- Testing
- Bone marrow sampling
- Where
- 18 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
Accommodation, Daily Activities
Project Independence
This project aims to develop and test the feasibility, acceptability, and preliminary impact of a brief, online single-session intervention (SSI) for caregivers of autistic youth ages 10 to 14.
- Conditions
- Accommodation, Daily Activities, Independence, Autism
- Trial name
- NCT07572110
- Testing
- Project Independence
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Miami
Hereditary Angioedema (HAE)
A Study of Lanadelumab in Teenagers and Adults With Hereditary Angioedema (HAE) in the Kingdom of Saudi Arabia
Hereditary angioedema (HAE) is a rare condition. It causes sudden swelling under the skin and inside the body, like in the belly, throat, or genitals.
- Trial name
- NCT07263685
- Testing
- No intervention
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Takeda
Autism
Better Social, Emotional Communication, Healthy Relationship and ASD Accommodation Skills: Emotional Intelligence ("EQ") Training for Autistic People and ASD Accommodation Training for People Who Care
Subjects are enrolled in pairs. Pairs consist of an autistic adult age 18-36 and a non-autistic learning partner who has a relationship with the autistic adult, such as a parent.
- Trial name
- NCT07315867
- Testing
- Kairon leadership training for the autistic adult and Kairon autism accommodation training for the learning partner
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kairon Connect, PBC
Mycosis Fungoides, Cutaneous T-cell Lymphoma
Topical JAK-Inhibition of Early-Stage CTCL
This study tests whether a cream named delgocitinib (Anzupgo), applied twice daily to the skin, is safe and well tolerated in people with early-stage cutaneous T-cell lymphoma (a rare type of skin cancer called mycosis…
- Trial name
- NCT07781449
- Testing
- delgocitinib
- Volunteers
- 15 people
- Sponsor
- Aarhus University Hospital
Knee Osteoarthritis, Knee Arthropathy
Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes
This study is a randomized controlled trial to assess whether the implementation of a TKA Personalized Outcome Prediction Tool to set expectation, in addition to targeted interventions to address patients with poor baseline…
- Conditions
- Knee Osteoarthritis, Knee Arthropathy, Surgery
- Trial name
- NCT06298721
- Testing
- Personalized outcome prediction tool + targeted interventions, Standard of Care TKA
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The Cleveland Clinic
Esotropia
Vision Therapy Versus Prism Treatment in Small-angle Acute Acquired Concomitant Esotropia
This prospective, single-center, nonrandomized comparative study evaluates 6-month ocular alignment and binocular visual function outcomes following combined accommodation and fusional training or prism correction in patients…
- Trial name
- NCT06622044
- Testing
- Vision therapy group, Prism
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Presbyopia, Esotropia
Accommodation-Related Visual Training Combined with Transcranial Electrical Stimulation Versus Visual Training Alone for the Treatment of Accommodation Dysfunction
This is a single-center, randomized controlled trial to compare the effectiveness of transcranial electrical stimulation combined with visual training with visual training alone for the treatment of accommodation disorder…
- Trial name
- NCT06714890
- Testing
- Transcranial Electrical Stimulation, Visual Training
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Eye & ENT Hospital of Fudan University