Clinical trials: Achalasia
Gastrointestinal Neoplasms, Achalasia
ConMed Beamer Study
This is a prospective registry of all patients who endoscopic submucosal dissection (ESD), per-oral endoscopic myotomy (POEM) and gastric per-oral endoscopic myotomy (G-POEM) using ConMed Electrosurgical unit for submucosal…
- Conditions
- Gastrointestinal Neoplasms, Achalasia, Gastroparesis
- Trial name
- NCT04752670
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Baylor College of Medicine
Esophageal Diseases, Achalasia
PRospective Registry of Esophageal Motility
Digestive physiopathology is a branch of gastroenterology aiming to study patients with upper GI symptoms, mainly gastro-esophageal, potentially indicating the presence of Gastroesophageal Reflux Disease (GERD)/Barrett Esophagus…
- Conditions
- Esophageal Diseases, Achalasia, Eosinophilic Esophagitis, Motility Disorder
- Trial name
- PREM (NCT07506746)
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
GERD
Post-POEM GERD in Patients Undergoing Conventional Versus Oblique Fibers Sparing Posterior Myotomy for Achalasia Cardia
In this study, we will evaluate the incidence of reflux esophagitis between two different techniques of posterior per-oral endoscopic myotomy (POEM) i.e. conventional POEM versus oblique/ sling fiber sparing POEM.
- Trial name
- POEM (NCT04229342)
- Testing
- Per-oral endoscopic myotomy
- Where
- India
- Volunteers
- 114 people
- Sponsor
- Asian Institute of Gastroenterology, India
Achalasia
Endoscopic Peroral Myotomy for Treatment of Achalasia
This study intends to investigate the feasibility, safety and efficacy of peroral endoscopic myotomy for the treatment of achalasia in a single center setting in Europe.
- Trial name
- POEM (NCT01405469)
- Testing
- Peroral Endoscopic Myotomy
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Achalasia, Dysphagia
Correlation of High Resolution Esophageal Manometry With Symptoms
High Resolution Manometry is a new technology that utilizes 36 solid state sensors on a thin catheter spaced at 1-cm intervals. One can more effectively measure the pressure of the esophagus.
- Conditions
- Achalasia, Dysphagia, GERD, Chest Pain
- Trial name
- NCT01202929
- Testing
- High Resolution Manometry
- Where
- United States
- Sponsor
- University of Louisville
Achalasia
POEM + F for Achalasia - a Pilot Study
This is a pilot study to investigate the feasibility of performing per-oral endoscopic Myotomy (POEM) with endoscopic fundoplication for patient with achalasia.
- Trial name
- NCT05214443
- Testing
- POEM + F
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- Chinese University of Hong Kong
Esophageal Achalasia
MARIMPACH : Contribution of High-resolution Manometry With Impedancemetry for the Evaluation of Esophageal Clearance in Achalasia
Outcome after treatment of achalasia is usually assessed by the Eckardt score (ES). The timed barium esophagogram (TBE) is used to objectively assess esophageal clearance after treatment.
- Trial name
- MARIMPACH (NCT06230536)
- Where
- France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Bordeaux
Achalasia, Achalasia Cardia
Nasogastric Tube After Laparoscopic Heller-Dor Myotomy
The goal of this prospective observational study is to evaluate the role of nasogastric tube (NGT) in patients with achalasia underwent to Heller-Dor laparoscopic.
- Trial name
- NCT05729971
- Testing
- nasogastric tube
- Where
- Italy
- Volunteers
- 79 people
- Sponsor
- Federico II University
Achalasia
Per-Oral Endoscopic Myotomy for Esophageal Swallowing Disorders
The purpose of this study is to show that the Per-Oral Endoscopic Myotomy (POEM) procedure is an effective treatment for people with achalasia.
- Trial name
- POEM (NCT02482337)
- Testing
- POEM
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Baylor Research Institute
Achalasia, Esophageal, Achalasia
The Use of Indocyanine Green Fluorescence (ICG) During Laparoscopic Heller- Dor
The aim this prospective observational study is to evaluate the role of Indocyanine Green Fluorescence (ICG) in patients with achalasia underwent to Heller-Dor laparoscopic.
- Conditions
- Achalasia, Esophageal, Achalasia, Indocyanine Green (ICG), Indocyanine Green
- Trial name
- NCT07181070
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Federico II University
Esophageal Achalasia
POEM vs. Pneumatic Dilation for Esophageal Achalasia
The purpose of this study is to determine the efficacy and safety of peroral endoscopic myotomy (POEM) compared with pneumatic dilation in the treatment of esophageal achalasia.
- Trial name
- NCT01768091
- Testing
- POEM, Pneumatic dilation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Esophageal Achalasia
Single- Versus Multiple-dose Antimicrobial Prophylaxis for The Prevention of Infectious Complications Associated With Peroral Endoscopic Myotomy(POEM) for Achalasia
Peroral endoscopic myotomy is a novel, promising endoscopic technique for achalasia considering its minimal invasive characteristics and comparable efficacy to Heller myotomy.
- Trial name
- NCT03404739
- Testing
- Saline Solution, Ceftazidime
- Where
- China
- Volunteers
- 666 people
- Sponsor
- Shanghai Zhongshan Hospital
Achalasia
Endoscopic Myotomy of the Lower Esophageal Sphincter for Achalasia
This is a study of the safety and efficacy of a new surgical procedure using endoscopic instruments and a tunneling technique to reach the LES for dissection.
- Trial name
- POEM (NCT01399476)
- Testing
- Endoscopic Myotomy, Endoscopic Myotomy for treatment of achalasia
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- The Oregon Clinic
Esophageal Achalasia
Per Oral Endoscopic Myotomy (POEM) and Prolonged Dilatation (PRD) for Achalasia
Achalasia is an esophageal motility disorder, which leads to clinical symptoms such as dysphagia, regurgitation, chest pain and consecutive weight loss.
- Trial name
- POETA (NCT02518542)
- Testing
- Endoscopic intervention A, Endoscopic intervention B, Endoscopic intervention C
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Achalasia
Hot Water Drinking Therapy in Achalasia
From clinical observation that some achalasia patients drink water to help swallow food, the investigators have proposed a systemic hot water drinking therapy.
- Trial name
- AHW (NCT01863966)
- Testing
- hot water drinking therapy, Pneumatic dilation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Achalasia Cardia
Serum Anti-enteric Neuronal Antibodies in Patients With Achalasia and Their Association With Clinical Profiles
Achalasia is a rare esophageal motility disorder characterized by impaired relaxation of the lower esophageal sphincter and progressive esophageal dilation.
- Trial name
- NCT07451301
- Testing
- peroral endoscopic myotomy (POEM)
- Where
- China
- Volunteers
- 195 people
- Sponsor
- Peking Union Medical College Hospital
Esophageal Achalasia
To Assess the Feasibility of Same Day Discharge Following a POEM Procedure
This is a study of an investigational surgical procedure for the treatment of achalasia the inability of smooth muscle to move food down the esophagus.
- Trial name
- POEM2 (NCT02572193)
- Testing
- POEM
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Esophageal Achalasia
Comparison Study of Conventional POEM and Hybrid POEM for Esophageal Achalasia
Peroral endoscopic myotomy (POEM) has recently been introduced as promising alternative to laparoscopic Heller myotomy for patients with idiopathic achalasia.
- Trial name
- NCT01742494
- Testing
- Water-jet POEM, Conventional POEM
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Zhongshan Hospital
Achalasia
POEM- Peroral Endoscopic Myotomy for Esophageal Motility Disorders
POEM has recently described as an alternative treatment for achalasia in humans. In this procedure the esophageal sphincter is incised through a submucosal tunnel in the esophagus.
- Trial name
- POEM (NCT01512719)
- Testing
- POEM
- Where
- 3 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Cricopharyngeal Achalasia
Ultrasound-guided Botulinum Toxin Injection on Cricopharyngeal Muscle Dysfunction
Ultrasound-guided injection is a visual, convenient, and radiation-free technique that allows real-time observation of the needle insertion process and drug injection location.
- Trial name
- NCT06328556
- Testing
- botulinum toxin type A, Injection
- Volunteers
- 30 people
- Sponsor
- Copka Sonpashan