Clinical trials: Acne Rosacea
Erythematotelangiectatic Rosacea
Intradermal BoNT-A Treatment in Erythematotelangiectatic Rosacea
Investigation of the effectiveness of intradermal botulinum toxin A treatment in the treatment of erythematotelangiectatic rosacea (ETR) using clinical, biophysical, dermatoscopic and videocapillaroscopy.
- Trial name
- NCT06331533
- Testing
- Botulinum toxin A
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Training and Research Hospital
Rosacea, Redness
Evaluation of the Efficacy and Tolerance of Two Cosmetic Products in Subjects With Rosacea
Multicentric and double-blind randomised comparative clinical study in Argentina and Brazil. Under dermatological and ophthalmological control 4 visits: inclusion [Day(D)0], D28, D56, D84 Ethical committee required.
- Conditions
- Rosacea, Redness, Telangiectasia, Flushing
- Trial name
- NCT06582043
- Testing
- SCARCr tester 1
- Where
- 2 sites in Argentina, Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- NAOS Argentina S.A.
Rosacea, Rosacea Subtype 1 (Erythematotelangiectatic)
Brimonidine 0.33% for Rosacea-Related Facial Erythema
This study looks at whether a topical gel called 0.33% brimonidine can reduce persistent facial redness caused by rosacea. The study was carried out in two parts.
- Trial name
- NCT07431476
- Testing
- Brimonidine 0.33% gel
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Training and Research Hospital
Demodex Infestation, Rosacea
Facial Demodicosis and Ocular Demodicosis
To understand the association between facial demodicosis and ocular demodicosis, we plan to enroll patients with facial demodicosis, ocular demodicosis, or both, in order to analyze their clinical presentations, the density of…
- Conditions
- Demodex Infestation, Rosacea, Blepharitis, Meibomian Gland Dysfunction
- Trial name
- NCT04377841
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Rosacea, Papulopustular Rosacea
Study to Evaluate the Safety and Efficacy of Topical Minocycline Gel in Patients With Papulopustular Rosacea
To evaluate the efficacy of once-daily application of 1% and 3% HY01 Topical Gel, as assessed by the change in inflammatory lesion count from baseline over the 12-week treatment period in patients with moderate-to-severe…
- Trial name
- NCT03263273
- Testing
- 1% Topical Minocycline Gel, 3% Topical Minocycline Gel, Topical Vehicle Gel
- Where
- 23 sites in United States
- Volunteers
- 270 people
- Sponsor
- Hovione Scientia Limited
Rosacea
A Pilot Study Testing the Effects of Chemical Peels in Patients With Rosacea
The study is a prospective, randomized, one-site therapeutic trial of 15% trichloroacetic acid (TCA) and 30% salicylic acid peels for rosacea. Two peels will be applied topically 4 weeks apart, and the study will end in 12 weeks.
- Trial name
- NCT04889703
- Testing
- 15% Trichloroacetic acid peel, 30% Salicylic acid peel
- Sponsor
- University of Texas Southwestern Medical Center
Rosacea
Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea
The purpose of this vehicle controlled study is to evaluate the efficacy and safety of CD07805/47 gel 0.5% applied topically once daily (QD) for 4 weeks, and CD07805/47 gel 0.18% applied topically once daily (QD) or twice daily…
- Trial name
- NCT01174030
- Testing
- CD07805/47 Gel, Vehicle Gel
- Where
- 20 sites in United States
- Volunteers
- 269 people
- Sponsor
- Galderma R&D
Papulopustular Rosacea
Deucravacitinib Rosacea
This will be a double-blind, randomized placebo-controlled study in which participants will be randomized 2:1 to receive 6 mg deucravacitinib or placebo once daily for 8 weeks, followed by an open label extension during which all…
- Trial name
- NCT06532136
- Testing
- Deucravacitinib
- Where
- United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
Rosacea
A Study to Evaluate the Safety and Efficacy of PAC-14028 Cream in Rosacea
This clinical study is to determine the optimum dose of PAC-14028 cream in a therapeutic confirmatory clinical study by evaluating the safety and therapeutic equivalence of PAC-14028 cream 0.1%, 0.3% and 1.0% in patients with…
- Trial name
- NCT02583009
- Testing
- PAC-14028 cream 0.1%, PAC-14028 cream 0.3%, PAC-14028 cream 1.0%
- Where
- South Korea
- Volunteers
- 216 people
- Sponsor
- Amorepacific Corporation
Rosacea
A Therapeutic Equivalence Study of Two Metronidazole 1%Topical Gel Treatments for Patients With Rosacea
The objective of this study is to demonstrate that metronidazole 1% topical gel is effective for the treatment of patients with moderate to severe rosacea.
- Trial name
- MTZG (NCT01513863)
- Testing
- Metronidazole Topical Gel 1%, Metronidazole Topical Gel 1% (Metrogel)
- Where
- 22 sites in United States
- Volunteers
- 602 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Rosacea
Genetic Basis of Rosacea
Rosacea is a common disease characterized by inflammation and vascular abnormalities of the facial skin and ocular surface. The exact pathogenesis of papulopustular rosacea is not well understood and current methods to treat this…
- Trial name
- NCT02787616
- Testing
- buccal swab
- Where
- United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Stanford University
Rosacea
PACAP38 Induced Headache and Rosacea-like Symptoms in Patients With Rosacea
The investigators aim is to investigate the incidence of headache and rosacea-like flushing after pituitary adenylate cyclase-activating peptide-38 (PACAP38) with and without treatment with sumatriptan in patients with rosacea
- Trial name
- NCT03878784
- Testing
- Imigran, Isotonic Saline
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- Danish Headache Center
Rosacea
Internet Surveys and Their Impact on Adherence for Rosacea
An investigator-blinded, prospective, 6 month study of subjects with persistent erythema associated with active rosacea will be conducted in 20 subjects aged 18 years and older.
- Trial name
- NCT03048058
- Testing
- brimonidine topical gel 0.33% & survey, brimonidine topical gel 0.33% & SOC
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wake Forest University Health Sciences
Rosacea
A Study to Evaluate Safety and Equivalence of Generic Azelaic Acid Foam and Finacea® Foam in Participants With Rosacea
The objectives of this study were to compare the safety and efficacy profiles of a generic Azelaic Acid Foam, 15% to the reference listed Finacea® (azelaic acid) Foam, 15% and to demonstrate therapeutic equivalence and safety of…
- Trial name
- NCT03287791
- Testing
- Generic Azelaic Acid Foam, Finacea® (Azelaic Acid) Foam, Vehicle Foam
- Where
- 26 sites in United States
- Volunteers
- 924 people
- Sponsor
- Actavis Inc.
Papulopustular Rosacea
An Analysis of the Effect of Topical Cromolyn Sodium on Rosacea-associated Erythema
This study is designed to investigate whether topical application of a cromolyn sodium solution is able to decrease the facial redness seen in patients with papulopustular rosacea. Previous work in the lab of Dr.
- Trial name
- NCT01933464
- Testing
- Cromolyn Sodium, Normal Saline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Diego
Rosacea, Vascular Diseases
Vbeam Pro Pulse Dye Laser for the Treatment of Vascular Conditions
This is a clinical study to evaluate the safety and performance of the Vbeam Pro Laser System for the treatment of vascular indications, including rosacea and port wine stain birthmarks.
- Conditions
- Rosacea, Vascular Diseases, Port-Wine Stain
- Trial name
- NCT07290426
- Testing
- Vbeam Pro Laser Treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Papulopustular Rosacea
A Twelve Week Safety and Efficacy Study in Rosacea
The purpose of this study is to evaluate th safety and efficacy of one-daily topical application of CLS001 low, mid and high dose compared to vehicle gel in subjects with papulopustular rosacea.
- Trial name
- NCT01784133
- Testing
- omiganan
- Where
- 17 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maruho Co., Ltd.