Clinical trials: Acne Scarring
Acne Scars
Clinical Evaluation of Fractional Radiofrequency for the Treatment of Acne Scarring
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring.
- Trial name
- NCT03767153
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Melasma, Acne Scars - Mixed Atrophic and Hypertrophic
Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser
More than aesthetics, the search for orofacial harmonization treatments has increased when the negative emotional impact of some facial conditions such as melasma and acne scars is recognized.
- Conditions
- Melasma, Acne Scars - Mixed Atrophic and Hypertrophic, Resurfacing, Rejuvenation
- Trial name
- NCT07036302
- Testing
- 35% TCA combined with croton oil peel, Isolate 35% TCA peel, Erbium-YAG laser
- Where
- 2 sites in Brazil
- Volunteers
- 120 people
- Sponsor
- Jose Roberto Cortelli
Acne Vulgaris, Isotretinoin
Investigation of the Effect of Oral Isotretinoin on Skin Thickness and Elasticity in Patients With Atrophic Acne Scar
Acne scar is a common complication of acne vulgaris (AV). Early and effective treatment of AV has a crucial role in managing both acne and acne scarring.
- Conditions
- Acne Vulgaris, Isotretinoin, Atrophic Acne Scar
- Trial name
- NCT05413200
- Testing
- Isotretinoin
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Training and Research Hospital
Skin Fold, Skin Laxity
A Safety and Effectiveness Study of CELLBOOSTER® Lift (Stabilized Booster Complex Using CHAC Technology)
The current post-market clinical investigation has been designed to evaluate the efficacy and safety of CELLBOOSTER® Lift, a HA-based product marketed by SUISSELLE SA.
- Conditions
- Skin Fold, Skin Laxity, Skin Texture Disorder, Skin Depression
- Trial name
- NCT06000839
- Testing
- (D0) Intradermal injection - micropapula technique, (D14) Intradermal injection - micropapula technique, (D28) Intradermal injection - micropapula technique
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Suisselle
Atrophic Acne Scars
Efficacy of Human UC-MSC-derived Exosomes and BM-MSC-derived Exosomes for Atrophic Acne Scar
The goal of this clinical trial is to learn if exosomes from human umbilical cord and bone marrow can improve atrophic acne scars when used after fractional CO₂ laser treatment in adults.
- Trial name
- NCT07510295
- Testing
- Exosomes derived from human umbilical cord and bone marrow mesenchymal stem cells, Hyaluronic Acid (HA)
- Where
- Vietnam
- Volunteers
- 22 people
- Sponsor
- Ngô Anh Tuấn
Acne Scars
Clinical Evaluation of Fractional Radiofrequency for the Treatment Acne Scarring
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring.
- Trial name
- NCT03821324
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Acne Vulgaris
Treatment of Acne Scars With Erbium:Yttrium Aluminum Garnet (Er:YAG) Laser Examined Under OCT
This study is examining the effects of the 2940 nm Er:YAG on atrophic facial acne scars under optical coherence tomography in terms of blood flow, vessel shape, skin roughness, collagen content, and epidermal thickness.
- Trial name
- NCT03333759
- Testing
- Alma - Harmony XL Laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Acne Vulgaris
Injectable POLY-L-Lactic Acid for Treatment of Hill and Valley Acne Scarring
Primary: Evaluate the degree of correction attainable with Poly-L-Lactic Acid(Sculptra) for the correction of hill and valley acne scarring Secondary: Document types and incidence of device adverse events with Poly-L-Lactic…
- Trial name
- NCT00795327
- Testing
- Sculptra (Poly-L-Lactic Acid Dermal Implant)
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Bausch Health Americas, Inc.
Acne Scars - Mixed Atrophic and Hypertrophic
Early Non-Ablative Fractional Laser Resurfacing for Acne Scars After Treatment With Oral Isotretinoin
Patients who have completed have completed a cumulative dose of >=120miligram/kilogram oral isotretinoin within the last 30 days, and has mild to moderate acne scarring will be randomized, into a right-left comparison study using…
- Trial name
- NCT03514771
- Testing
- Fraxel DUAL 1550/1927, oral isotretinoin, oral valacyclovir
- Volunteers
- 15 people
- Sponsor
- David Smart
Acne Scars
Effect of Multiple Subcisions on Rolling Acne Scars
The purpose of this study is to find out whether the use of multiple subcisions over several visits will improve the appearance of rolling acne scars compared to no treatment.
- Trial name
- NCT02216864
- Testing
- Multiple Subcision
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Acne, Acne Scars
The Suitability of Tience® for Treating Acne Scars
This is an open-label, single-center, split-face, pseudo-randomized clinical trial designed to evaluate the efficacy and safety of a human-derived, cell-free adipose tissue derivative (Tience® ), for treating moderate to severe…
- Trial name
- NCT07368764
- Testing
- Intradermal injections
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Linio Biotech Oy
ACNE SCARRING
A Pilot Study to Determine Safety & Efficacy of Autologous Human Platelet Lysate (HPL) in Treatment of Acne Scarring
This is a multicentre, open label, randomized, pilot study to evaluate safety and efficacy of Human Platelet Lysate (HPL) in subjects with Acne Scarring. The study is being conducted at 2 centers in India.
- Trial name
- NCT01644435
- Testing
- Autologous Human Platelet Lysate
- Where
- India
- Volunteers
- 19 people
- Sponsor
- Kasiak Research Pvt. Ltd.
Acne, Wrinkle
Fractional Radiofrequency for Treatment of Acne Scars and Wrinkles
This study will evaluate the clinical efficacy, safety and the performance of the fractional radiofrequency delivered by the BTL-585-4 applicator of the BTL-585F system for non-invasive treatment of acne scars and facial…
- Trial name
- NCT05827510
- Testing
- BTL-585F
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Atrophic Acne Scar
Efficacy of Intralesional Injection of Pentoxifylline, Platelet-Rich Plasma, and Combined Pentoxifylline With Platelet-Rich Plasma in Patients With Atrophic Acne Scars
Platelet-rich plasma (PRP) is an Acne vulgaris is a common chronic inflammatory skin disorder. It is the eighth most prevalent disease worldwide with a prevalence of 9.4%.
- Trial name
- NCT06319768
- Testing
- Pentoxifylline, platelet rich plasma, combined pentoxifylline and platelet rich plasma
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Sohag University
Atrophic Acne Scarring
The Use of Bellafill for Atrophic Acne Scar Correction in the Full Facial Area
This is an open-label, multicenter, prospective pilot study assessing the efficacy and safety of Bellafill for correction of distensible atrophic acne scars in the full facial area.
- Trial name
- NCT02642627
- Testing
- Bellafill
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Suneva Medical, Inc.
Atrophic Acne Scars
A Pilot Study to Evaluate the Safety and Effectiveness of Microneedling and Bellafill to Treat Facial Acne Scars
This is an open-label, randomized, multicenter, prospective trial assessing the efficacy and safety of microneedling treatment alone vs.
- Trial name
- NCT02643628
- Testing
- Microneedling, Microneedling followed by Bellafill treatment
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Suneva Medical, Inc.
Atrophic Acne Scar
Simultaneous Versus Sequential Fractional CO2 Laser and Subcision Combination for Post-acne Atrophic Scars: A Split-face Comparative Study.
Acne vulgaris, a disease of the pilosebaceous unit, is estimated to afflict 9.4% of the global population, making it the eighth most prevalent and third most significant disease according to the global burden of disease.
- Trial name
- NCT05688202
- Testing
- Simultaneous combination of fractional CO2 laser and subcision, Sequential combination of fractional CO2 laser and subcision, Fractional CO2 laser
- Where
- Vietnam
- Volunteers
- 34 people
- Sponsor
- Ho Chi Minh City Hospital of Dermato-Venereology
Atrophic Acne Scar
Subcision With CO₂ Laser or PRP vs Subcision Alone in Atrophic Acne Scars
Acne vulgaris is an inflammatory disease of pilosebaceous unit ,leading to different types of scars including atrophic, hypertrophic and keloidal.
- Trial name
- NCT07199608
- Testing
- subcision, subcision+fractional co2 laser, subcision+PRP
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Acne Scar
Clinical Effect of Platelet Rich Plasma Combined With Laser on Scar
Investigation of Clinical Effect of Platelet Rich Plasma Combined With Laser on Acne Scar
- Trial name
- NCT02396290
- Testing
- fractional carbon dioxide laser with platelet rich plasma, fractional carbon dioxide laser with NS
- Where
- South Korea
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Atrophic Acne Scarring
Poly-L-Lactic Acid in Atrophic Acne Scars
Background: Management of atrophic acne scars remains challenging due to their heterogeneous morphology and suboptimal response to conventional therapies.
- Trial name
- NCT07523217
- Testing
- injectable PLLA, PLLA threads
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University