Clinical trials: Acne Vulgaris
Acne Vulgaris
Treatment of Moderate to Severe Facial Acne Vulgaris
Randomized, multi-center, double-blind, placebo-controlled 12-week study to assess the safety and efficacy of 3 doses of an oral formulation of Doxycycline oral tablets using the Investigator's Global Assessment (IGA) score and…
- Trial name
- NCT00612573
- Testing
- Doxycycline 0.6 mg/kg/day, Doxycycline 1.2 mg/kg/day, Doxycycline 2.4 mg/kg/day
- Where
- 23 sites in United States
- Volunteers
- 257 people
- Sponsor
- Warner Chilcott
Acne Vulgaris
Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne Medications
This is a single-blind (blinded expert grader), randomized, half-face study being conducted at one clinical site. On 1 side of the face, the subject will apply 1 of the 2 test products, antibiotic and benzoyl peroxide or benzoyl…
- Trial name
- NCT00926367
- Testing
- Clindamycin and benzoyl peroxide, benzoyl peroxide 2.5% and adapalene 0.1% gel
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
Efficacy Study in Patients With Acne Vulgaris.
Safety and efficacy study in patients with acne vulgaris
- Trial name
- NCT02935036
- Testing
- ADPS topical product
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Vulgaris
Study of Efficacy and Safety of CJM112 in Patients With Moderate to Severe Inflammatory Acne
The study was designed primarily to assess preliminary efficacy and safety of CJM112 in patients with moderate to severe inflammatory acne and to determine if CJM112 has an adequate clinical profile for further clinical…
- Trial name
- NCT02998671
- Testing
- CJM112
- Where
- 10 sites in United States, Germany and 1 more
- Volunteers
- 52 people
- Sponsor
- Novartis Pharmaceuticals
Acne Vulgaris
Safety and Efficacy Study of Clindamycin/Benzoyl Peroxide/Tazarotene Cream in Subjects With Acne
Benzoyl peroxide, clindamycin and tazarotene are known to be effective treatment alternative for acne vulgaris. The purpose of this study is to assess the safety and efficacy of a combination product including these actives for…
- Trial name
- NCT00713609
- Testing
- Benzoyl peroxide gel, Clindamycin gel, Tazarotene cream
- Where
- 16 sites in United States
- Volunteers
- 591 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
A Study of the Safety and Efficacy of DFD-03 Lotion in the Treatment of Acne Vulgaris for 12 Weeks
Enrollment of subjects with mild to moderate facial acne vulgaris. Co-Primary efficacy endpoints included: Absolute change from Baseline to Week 12 in the inflammatory lesion counts on the face Absolute change from Baseline to…
- Trial name
- NCT03292640
- Testing
- DFD-03 (0.1% tazarotene) Lotion
- Where
- United States
- Volunteers
- 547 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Acne Scars - Mixed Atrophic and Hypertrophic
Comparison of 1,550 and 755 Laser in a Split-face Trial
Clinical Trial comparing the 1,550-nanometer fractionated photothermolysis system laser to the 755 nanometer picosecond laser using a split-face (Right-Left) comparison.
- Trial name
- NCT03988049
- Testing
- 1,550 fracionated photothermolysis laser, 755 picosecond laser
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- David Smart
Acne Vulgaris
Pharmacokinetic Study to Compare the Systemic Exposure of Differin® Gel, 0.3% or Differin® Gel, 0.1%
Phase 4 commitment pharmacokinetic study to determine systemic exposure to adapalene.
- Trial name
- NCT00660985
- Testing
- Adapalene
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Compare the Tolerance of Clindamycin 1% /Benzoyl Peroxide (BPO) 5% Gel to Clindamycin 1.2%/ BPO 2.5% Topical Medications
This is a single-blind (blinded expert grader) study that will enroll 25-30 healthy volunteers without facial acne. On 1 side of the face, the subject will apply 1 of the 2 test products, clindamycin and benzoyl peroxide 5% or…
- Trial name
- NCT01015638
- Testing
- Clindamycin and BPO 5% gel, Clindamycin phosphate and benzoyl peroxide 2.5% gel.
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Hidradenitis Suppurativa
Open-label Study of the Safety and Efficacy of Adalimumab in the Treatment of Hidradenitis Suppurativa
The purpose of this study to evaluate the long term safety, tolerability and efficacy of adalimumab in subjects with moderate to severe hidradenitis suppurativa (HS).
- Trial name
- PIONEER (OLE) (NCT01635764)
- Testing
- adalimumab
- Volunteers
- 508 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Acne Vulgaris
Clinical Trial in Subjects With Mild to Moderate Acne Vulgaris
The purpose of this study is to demonstrate the safety, tolerability and efficacy of B244 administered over 12 weeks to participants with mild to moderate acne vulgaris relative to placebo.
- Trial name
- NCT02832063
- Testing
- B244
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- AOBiome LLC
Atrophic Acne Scar
SkinPen Efficacy on Acne Scars on the Face and/or Back
This single-center, clinical trial will take place over a 90 day course followed by 1-month and 6-month post treatment visits to assess the efficacy and tolerability of the SkinPen device when used on both men and women on the…
- Trial name
- NCT02646917
- Testing
- Aesthetic Microneedling Treatment
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Bellus Medical, LLC
Acne
Clinical Study to Test the Efficacy and Safety of ACYC to Treat Moderate to Severe Acne
The primary objective of this study is to compare the efficacy and safety and tolerability of ACYC Gel and vehicle in the treatment of subjects with Acne Vulgaris.
- Trial name
- ACYC (NCT01701024)
- Testing
- ACYC, ACYC vehicle
- Where
- 24 sites in United States
- Volunteers
- 498 people
- Sponsor
- Bausch Health Americas, Inc.
Acne
Study of the Use of Low Level Laser Therapy to Reduce Acne
The purpose of this study is to determine whether low level laser light therapy is effective in the treatment of acne blemishes.
- Trial name
- NCT01276535
- Testing
- Erchonia MLS + Erchonia THL
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation
Acne Vulgaris, Acne
A Clinical Study to Evaluate the Safety and Effectiveness of an Investigational Product Called CT Gel
The purpose of this study is to demonstrate the safety and effectiveness of CT Gel in subjects with acne vulgaris. The hypothesis is that CT Gel is superior to Clindamycin Gel, Tretinoin Gel and Vehicle Gel for the treatment of…
- Trial name
- NCT00689117
- Testing
- CT Gel, Clindamycin Gel (clindamycin ), Tretinoin Gel (tretinoin)
- Where
- 32 sites in United States, Belize and 1 more
- Volunteers
- 1,649 people
- Sponsor
- Stiefel, a GSK Company
Actinic Keratosis
Perimenstrual Acne With Clindamycin Phosphate and Benzoyl Peroxide
The study team plans to enroll a total of 40 subjects with self-reported perimenstrual acne. Eligible women will be over the age of 18 and not on any current therapy.
- Trial name
- NCT03122457
- Testing
- lidamycin phosphate and benzoyl peroxide 1.2%/3.75% combination
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Acne Vulgaris
Safety and Efficacy of the Use of Botox on Acne
To determine the safety and efficacy of Botox Treatment in subjects with mild to moderate acne vulgaris defined by the Investigator's Global Assessment (IGA)
- Trial name
- NCT00765375
- Testing
- Botulinum Neurotoxin Type A, Bacteriostatic saline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- DeNova Research
Acne Vulgaris
An Evaluation of the Adrenal Suppression Potential and Pharmacokinetic Properties of CB-03-01 Cream in Subjects With Acne Vulgaris
This study is designed to determine the hypothalamic-pituitary-adrenal (HPA) axis suppression potential and pharmacokinetic (PK) properties of CB-03-01 Cream, 1%, applied every twelve hours for two weeks, in subjects with acne…
- Trial name
- NCT01831960
- Testing
- cortexolone 17α-propionate
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Intrepid Therapeutics, Inc.
Hidradenitis Suppurativa (Acne Inversa)
Efficacy, Safety, and Pharmacokinetics Study of CJM112 in Hidradenitis Suppurativa Patients
This is a randomized, double blind, multicenter study in patients with moderate to severe chronic hidradenitis suppurativa in parallel groups, to determine the efficacy and safety of multiple doses of CJM112 in comparison to…
- Trial name
- NCT02421172
- Testing
- CJM112
- Where
- 16 sites in United States, Denmark and 3 more
- Volunteers
- 66 people
- Sponsor
- Novartis Pharmaceuticals
Acne Vulgaris
A Study Assessing the Efficacy and Safety of Combined Use of Clascoterone 1% Cream and Duac Gel (Benzoyl Peroxide/Clindamycin) for the Treatment of Acne
Winlevi is the first topical anti androgen and sebum inhibitor approved for acne vulgaris. There is no study assessing Winlevi in combination treatment for acne .Therefore this study assesses Winlevi with Duac gel in combination…
- Trial name
- NCT06336629
- Testing
- Winlevi (clascoterone) 1% & Duac gel
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sun Pharmaceutical Industries Limited