Clinical trials: Acquired Immune Deficiency Syndrome Virus
Stimulant Use (Diagnosis), Hiv
Contingency Management in HIV Care for Both Stimulant Use & ART Adherence
Methamphetamine use and associated sequelae have been rising, and represent a major barrier to successful control of the HIV epidemic.
- Trial name
- CoMBo (NCT06564792)
- Testing
- Contingency management
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of California, San Francisco
Human Immunodeficiency Virus
Study of Entry and Continuation in Care for People Living With HIV in French Guiana
Research Involving the Non-Interventional Human Subject (RIPH category 3). Non-interventional, cross-sectional, multicentre, descriptive and analytical epidemiological study.
- Trial name
- EMVIH (NCT05354934)
- Testing
- quetionnaire
- Where
- French Guiana
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier de Cayenne
HIV Infection
A Safety and Immune Response Study of 2 Experimental HIV Vaccines
The HIV Vaccine Trials Network (HVTN) is doing a study to test a new HIV vaccine combination. HIV is the virus that causes AIDS. 252 people are taking part in this study at multiple sites.
- Trial name
- NCT02404311
- Testing
- ALVAC-HIV, Bivalent Subtype C gp120/MF59®
- Where
- 5 sites in South Africa
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV/AIDS
ADAPT for Adolescents Adolescents
Adolescents and young adults (AYA) with HIV face unique challenges to engagement in care and their ability to achieve optimal health outcomes.
- Trial name
- A4A (NCT04432571)
- Testing
- SOC-REC/SOC-OIC, SOC-REC/CCT, SOC-REC/IP-NAV
- Where
- Kenya
- Volunteers
- 880 people
- Sponsor
- Washington University School of Medicine
HIV Infection, Substance Abuse
A Self-Assessment Intervention for Young Adult Polydrug Users at Risk for HIV
The proposed study is a three-armed randomized clinical trial. A total of 750 clients will be randomly assigned (using a random number table) to the interviewer-administered intervention, the self-administered intervention, and…
- Trial name
- NCT01362634
- Testing
- Trans-theoretical Process of Change Model-self, Trans-theoretical Process of Change Model - interviewer
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Nova Southeastern University
HIV Infections, Acquired Immunodeficiency Syndrome
Safety and Efficacy of an Investigational Drug in Human Immunodeficiency Virus (HIV)-Infected Patients Failing Current Antiretroviral Therapies (0518-005)(COMPLETED)
This study will investigate the safety and efficacy of different doses of an investigational drug (MK0518) as a therapy for HIV-infected patients failing current antiretroviral therapies.
- Trial name
- NCT00105157
- Testing
- Comparator: MK0518, MK0518
- Volunteers
- 179 people
- Sponsor
- Merck Sharp & Dohme LLC
HIV/AIDS
PrEP Communication Intervention for Female Clients of a Needle Exchange
This study will identify perceptions of PrEP in women who inject drugs (WWIDs) and develop and pilot test a targeted intervention that will be embedded in a large, urban syringe exchange program through an extensive formative…
- Trial name
- NCT03541642
- Testing
- Enhanced Intervention, Basic Intervention
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Temple University
HIV Infections
A Study of DTC in Patients With AIDS and AIDS Related Complex
To determine if ditiocarb sodium (sodium diethyldithiocarbamate; DTC) restores immune and host defense function; if DTC ameliorates the AIDS related complex (ARC) symptoms in patients with AIDS and ARC; if DTC prevents…
- Trial name
- NCT00002069
- Testing
- Ditiocarb sodium
- Where
- 8 sites in United States
- Sponsor
- Merieux Institute
Infection, Human Immunodeficiency Virus
Single and Repeated Dose Escalation Study of GSK2838232
GSK2838232 is a Human Immunodeficiency Virus (HIV) maturation inhibitor being developed for the treatment of HIV in combination with other antiretroviral therapy (ART).
- Trial name
- NCT02795754
- Testing
- GSK2838232 PIB, GSK2838232 IR1, GSK2838232 IR2
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acquired Immunodeficiency Syndrome, HIV Infections
Study to Evaluate Switching From Regimens Consisting of a Nonnucleoside Reverse Transcriptase Inhibitor Plus Emtricitabine and Tenofovir DF to the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir DF Single-Tablet Regimen in Virologically Suppressed, HIV-1 Infected Patients
This study will evaluate the noninferiority of Stribild® (elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate (E/C/F/TDF)) single-tablet regimen (STR) relative to regimens consisting of a nonnucleoside reverse…
- Trial name
- NCT01495702
- Testing
- NNRTI, FTC/TDF, Stribild
- Where
- 80 sites in United States, Australia and 10 more
- Volunteers
- 439 people
- Sponsor
- Gilead Sciences
Sarcoma, Kaposi, HIV Infections
Topical Use of 4,4'-Dihydroxybenzophenone-2,4-Dinitrophenylhydrazone (A-007) in the Treatment of Advanced Malignancies Including Kaposi's Sarcoma and Lymphoproliferative Disorders
To evaluate topical A-007 in patients with advanced malignancies including Kaposi's sarcoma and lymphoproliferative disorders.
- Conditions
- Sarcoma, Kaposi, HIV Infections, Lymphoproliferative Disorders
- Trial name
- NCT00002153
- Testing
- A-007
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- DEKK-TEC, Inc.
Human Immunodeficiency Virus Infection, Inflammation
Gene Expression Outcomes in Interventions for Substance Using HIV+ Minority Men
This is a pilot study of a new 9-session individually delivered cognitive behavioral intervention targeting sexual minority stress.
- Trial name
- NCT03143205
- Testing
- AWARENESS for Sexual Minorities, Writing tasks
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Infectious Disease
The All Ireland Infectious Diseases Cohort Project
The All-Ireland Infectious Diseases (AIID) Cohort is a multicentre, prospective, longitudinal observational cohort that enrols consecutive adult subjects attending participating institutions for infectious disease services.
- Trial name
- AIID (NCT06410053)
- Where
- 9 sites in Ireland
- Volunteers
- 10,000 people
- Sponsor
- University College Dublin
HIV (Human Immunodeficiency Virus)
The Eswatini Study on Neurocognitive Performance in Adolescents Living With HIV
This study explores the link between inflammatory biomarkers and neurocognitive performance in adolescents living with HIV (ALHIV) in Eswatini.
- Trial name
- NCT07165639
- Where
- Eswatini
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Eswatini Nazarene Health Institutions
HIV/AIDS, Liver Diseases
Liver Diseases in PLWH
In Highly Active Antiretroviral Therapy era, fatty liver has become an important cause of liver function damage in people living with HIV (PLWH).
- Trial name
- NCT04446156
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
HIV Infections
A Study of L-735,524 in HIV-Positive Children and Adolescents
To evaluate the safety, tolerability, and plasma concentration profiles of indinavir sulfate ( MK-639; Crixivan ) in HIV-seropositive older children and adolescents.
- Trial name
- NCT00002351
- Testing
- Indinavir sulfate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Merck Sharp & Dohme LLC
Peripheral Neuropathy, HIV
Acupuncture/Moxibustion (Acu/Moxa) for Distal Symmetric Peripheral Neuropathy (DSP) in HIV
This preliminary study will investigate the use of Acupuncture and Moxibustion (Acu/Moxa) for distal symmetric peripheral neuropathy (DSP) associated with HIV applying traditional Chinese medicine (TCM) evaluations conducted by a…
- Conditions
- Peripheral Neuropathy, HIV, AIDS, HIV Infections
- Trial name
- TCMAcuPilot (NCT00826345)
- Testing
- Acupuncture / Moxibustion, Acupuncture/Moxibustion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Human Immunodeficiency Virus
Safety And Efficacy Study Of CP-675,206 In HIV-Infected Patients
The purpose of this study is to determine if CP-675,206, a monoclonal antibody to CTLA4, is safe and well-tolerated, reduces viral load, and improves immune function in patients infected with HIV.
- Trial name
- NCT00488995
- Testing
- CP-675,206
- Sponsor
- Pfizer
Tuberculosis, Hiv
Kharituwe TB Contact Tracing Study
The purpose of this study is to characterize the role of human mobility in fueling TB epidemics and estimate the potential impact of innovative case finding interventions tailored to mobile populations
- Trial name
- NCT04520113
- Testing
- Household contact tracing
- Where
- 2 sites in South Africa
- Volunteers
- 10,579 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Alcohol Dependence, Problem Drinking
Alcohol Pharmacotherapy for HIV+ Prisoners
This is a randomized controlled trial of injectable intramuscular naltrexone (XR-NTX) versus intramuscular placebo among HIV-infected prisoners meeting Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition…
- Conditions
- Alcohol Dependence, Problem Drinking, Hazardous Drinking, Human Immunodeficiency Virus
- Trial name
- INSPIRE (NCT01077310)
- Testing
- Vivitrol- Intramuscular naltrexone (depot-formulation)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
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