Clinical trials: Acquired Immune Deficiency Syndrome Virus
HIV Infection, HIV Infections
Integration of Family Planning and HIV Services in Tanzania
HIV positive women and couples have broad reproductive health needs that are not always met within HIV services. The integration of family planning (FP) services into Tanzania's HIV Care and Treatment Clinics (CTC) will address…
- Trial name
- NCT00941876
- Testing
- Facilitated Referral
- Where
- Tanzania
- Volunteers
- 864 people
- Sponsor
- FHI 360
HIV Infections, Cardiovascular Diseases
Implementation and Effectiveness of Physical Activity to Prevent Disability in HIV-infected Adults Older Than 50 From Côte d'Ivoire
The overall objective of this research is to provide evidence on the effectiveness and implementation of two strategies deliver a structured programme of physical activity (PA) people living with HIV older than 50 years from…
- Conditions
- HIV Infections, Cardiovascular Diseases, Insulin Resistance Syndrome X
- Trial name
- VIRAGE+ (NCT06139497)
- Testing
- Physical activity programme, Home-based physical activity
- Where
- 2 sites in Côte d’Ivoire
- Volunteers
- 180 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Sexually Transmitted Diseases, Pregnancy
All About Youth: Evaluation of Sexual Risk Avoidance and Risk Reduction Programs for Middle School Students
This study will evaluate the efficacy of two curricula relative to standard care. The first is a sexual risk avoidance curriculum for middle school students that included abstinence until marriage and complies with Title V…
- Conditions
- Sexually Transmitted Diseases, Pregnancy, HIV Infections
- Trial name
- NCT00167505
- Testing
- Risk Avoidance Intervention, Risk Reduction Intervention
- Where
- United States
- Volunteers
- 1,742 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Stigma, Social, HIV/AIDS
Transgender Education for Affirmative and Competent HIV and Healthcare
Educational workshops are an efficacious strategy to increase healthcare providers' ability to provide gender-affirming care for transgender (trans) people.
- Conditions
- Stigma, Social, HIV/AIDS, Health Care Acceptability
- Trial name
- TEACHH (NCT04096053)
- Testing
- TEACHH
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Toronto
HIV Infections, Cytopenias
Treatment Program for Anemia in AIDS Patients
The objective of the Eprex (erythropoietin) Treatment Program is to provide erythropoietin for the treatment of anemia in AIDS patients.
- Trial name
- NCT00002022
- Testing
- Epoetin alfa
- Where
- United States
- Sponsor
- R W Johnson Pharmaceutical Research Institute
Infection, Human Immunodeficiency Virus
Study to Evaluate the Effect of Food on the Pharmacokinetics of BMS-626529
The current food effect study is being performed to support a Phase 3 study with BMS 663068. Results from this study will inform whether patients in the upcoming Phase 3 study can be given the flexibility to dose BMS-663068 in…
- Trial name
- NCT02164045
- Testing
- BMS-663068
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Alcohol Use Disorder, HIV/AIDS
Understanding and Intervening With Heavy Drinking Among Patients With HIV and HCV
Among patients with HIV, especially those also infected with HCV, heavy drinking is associated with significant risks to health.
- Conditions
- Alcohol Use Disorder, HIV/AIDS, Hepatitis C, Binge Drinking
- Trial name
- NCT03652675
- Testing
- Intervention: (Clinician's Guide + HealthCall for HIV/HCV)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- New York State Psychiatric Institute
Human Immunodeficiency Virus, Opioid Use Disorder
Combined Injectable Treatment for HIV and OUD
This is study seeks to evaluate perspectives of a combined injectable treatment for HIV and OUD. Specifically, with the development of new long-acting medications such as cabotegravir co-administered with rilpivirine (CAB/RPV)…
- Trial name
- CHOICE (NCT05991622)
- Testing
- Combined LAI Treatment: Cabenuva and Sublocade
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Anti-Retroviral Agents, HIV-1
TMC125-C203: Phase II Randomized (Patients Are Assigned Different Treatments Based on Chance), Placebo Controlled Dose Escalating Trial of TMC125 in HIV-1 Infected Patients
The purpose of this randomized (patients are assigned different treatments based on chance), placebo-controlled, dose-escalating trial is to evaluate the safety, tolerability and efficacy of different doses of TMC125 twice daily…
- Trial name
- NCT00412646
- Testing
- TMC125
- Volunteers
- 260 people
- Sponsor
- Tibotec Pharmaceuticals, Ireland
COVID-19 Pandemics, Human Immunodeficiency Virus
The Impact Evaluation of the COVID-19 Prevention on Risk Factors of HIV and Sexually Transmitted Comorbidity
This is a cross-sectional research. The Protection Motivation Theory (PMT) was applied as theoretical framework to analyze correlation of prevention knowledge, prevention intentions and anxiety, and prevention behavior of…
- Trial name
- NCT05188456
- Where
- Taiwan
- Volunteers
- 2,200 people
- Sponsor
- National Taiwan University
HIV - Human Immunodeficiency Virus
Multiple Interventions With Distinct Anti-reservoir Activities in People on Antiretroviral Treatment
Contemporary ART fails to eradicate the HIV-1 virus from PWH, resulting in a rebound in viremia within days to weeks after cessation of ART.
- Trial name
- NCT07903441
- Testing
- Multiple therapeutic interventions
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Federal University of São Paulo
Acquired Immunodeficiency Syndrome, HIV Infection
Multicenter, Safety Study Of Maraviroc
To collect safety and tolerability data in a more diverse patient population of patients with HIV/Aids, who have limited therapeutic options.
- Trial name
- NCT00478231
- Testing
- Maraviroc
- Where
- 16 sites in Brazil
- Volunteers
- 209 people
- Sponsor
- ViiV Healthcare
HIV, AIDS
Kaiser Permanente HIV Cohort Study
Human Immunodeficiency Virus (HIV) infected patients in the Kaiser Permanente HIV registry wil be followed in the usual clinical care to estimate the rates of specified clinical events.
- Trial name
- NCT01339403
- Testing
- non-interventional trial
- Volunteers
- 282,368 people
- Sponsor
- ViiV Healthcare
Cryptococcal Meningitis, Cryptococcus Neoformans
Operational Research for Cryptococcal Antigen Screening
This will be a stepped wedge randomized trial design to evaluate the implementation of cryptococcal antigen (CRAG) screening and preemptive anti-fungal therapy of HIV-infected persons entering antiretroviral therapy (ART)…
- Conditions
- Cryptococcal Meningitis, Cryptococcus Neoformans, Cryptococcosis
- Trial name
- ORCAS (NCT01535469)
- Testing
- Fluconazole
- Where
- 2 sites in Uganda
- Volunteers
- 3,049 people
- Sponsor
- University of Minnesota
HIV Infection, AIDS
HIV Liver Regeneration Project for HIV Patients With Cirrhosis by Autologous Bone Marrow Transplantation
An international investigation to evaluate if, and if so how long, autologous bone marrow hematopoietic stem cell transplantation can safely restore liver functions for HIV infected patients who have decompensated liver cirrhosis.
- Conditions
- HIV Infection, AIDS, Cirrhosis
- Trial name
- HIV-ABMi (NCT01309594)
- Testing
- Hematopoietic stem cell transplantation
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- National Center for Global Health and Medicine, Japan
HIV Infections
Study to Evaluate the Effect of GSK3640254 on the Pharmacokinetics of Tenofovir Alafenamide/Emtricitabine
Human immunodeficiency virus (HIV) infection frequently involves combination drug therapy for its treatment; hence, it is important to understand their interactions and resulting changes in exposure which are associated with…
- Trial name
- NCT03836729
- Testing
- Tenofovir alafenamide/emtricitabine, GSK3640254
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
HIV/AIDS
Behavioral Intervention to Enhance HIV Test/Treat
Prevention strategies that aim to test and treat people for HIV infection are undermined by HIV treatment non-adherence and sexually transmitted co-infections (STI).
- Trial name
- NCT01752777
- Testing
- Infectiousness Risk Reduction, General Health Improvement
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Connecticut
HIV (Human Immunodeficiency Virus), Chlamydia
Evaluation of Free STI Testing Pilot Projects in Lucerne and Zurich, Switzerland
The main goal of the observational study is to evaluate participants' satisfaction with free HIV and sexually transmitted infection (STI) testing and counselling offered by the cities of Lucerne and Zurich, Switzerland to young…
- Conditions
- HIV (Human Immunodeficiency Virus), Chlamydia, Gonorrhea, Syphilis
- Trial name
- feSTI (NCT07516912)
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University of Zurich
HCV HIV
Community-based Treatment of Chronic Hepatitis C Monoinfection and Coinfection With HIV in the District of Columbia
Background: Treatment for Hepatitis C has changed a lot in the past 2 years. Most of this change comes from a combination of medicines that is yielding high cure rates. But its long-term effects are uncertain.
- Trial name
- NCT02339038
- Testing
- Ledipasvir 90 mg and Sofosbuvir 400 mg
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Candidiasis, Esophageal, HIV Infections
A Comparison of Fluconazole and Ketoconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems
To compare the safety, tolerance, and effectiveness of fluconazole and ketoconazole in the treatment of candidal esophagitis in immunocompromised patients.
- Trial name
- NCT00002304
- Testing
- Ketoconazole, Fluconazole
- Where
- 42 sites in United States, Canada
- Sponsor
- Pfizer