Clinical trials: Acquired Immune Deficiency Syndrome Virus
Depression Disorders, HIV (Human Immunodeficiency Virus)
Improving the Treatment of Depression Among Youth With HIV
Depression is a common psychiatric condition among Youth with HIV (YWH), with prevalence as high as 25% in the United States. The treatment of depression is essential for improving both psychiatric and medical outcomes for YWH…
- Trial name
- NCT07211087
- Testing
- COMBEX, COMB
- Volunteers
- 130 people
- Sponsor
- Rhode Island Hospital
HIV Infections, Lymphoma, AIDS-Related
Evaluation of Brain Lesions in HIV-infected Patients for Diagnosis of Primary Central Nervous System Lymphoma
This study will evaluate the usefulness of two tests in quickly distinguishing whether a patient with HIV infection and focal brain lesions (an injury in a specific area of the brain) has a rare type of cancer called primary…
- Trial name
- NCT00226304
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
HIV Infections
A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Patients With AIDS and AIDS-Related Complex
To determine the safety profile and maximum tolerated dose (MTD) of recombinant soluble human CD4 (rCD4) therapy in patients with AIDS or AIDS related complex (ARC). To assess pharmacokinetic properties of rCD4 in humans.
- Trial name
- NCT00002004
- Testing
- CD4 Antigens
- Where
- United States
- Sponsor
- Genentech, Inc.
HIV Infections
Three Generic Nevirapine-Based Antiretroviral Treatments in Chinese Patients:Multicentric Observation Cohort
The purpose of this study is to determine whether the three generic nevirapine-based antiretroviral regimens are effective in the treatment of Acquired immune deficiency syndrome .
- Trial name
- NCT00618176
- Testing
- Zidovudine (AZT)+ Didanosine (ddI)+ Nevirapine (NVP), Stavudine (d4T), Lamivudine (3TC), Nevirapine (NVP), Zidovudine (AZT), Lamivudine (3TC), Nevirapine (NVP)
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Peking Union Medical College
Heart Diseases, Hiv
Whole Food Plant-Based Diet for HIV-Associated Reduction in Cardiovascular Risk (PLANT-HART)
The goal of this clinical trial is to evaluate the impact of using a whole food plant-based diet in the reduction of cardiovascular risk related to HIV in people who live with HIV infection.
- Trial name
- PLANT-HART (NCT05796882)
- Testing
- Whole Food Plant-Based Diet Ad Libitum, Nutritional Standard Care
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Universidad Autonoma de Chihuahua
Cerebral Toxoplasmosis, AIDS
Cerebral Toxoplasmosis and AIDS
With a HIV incidence much higher in the DFA than in European French territory, this disease is a major public health problem in these areas, especially in French Guiana.
- Trial name
- TOXODFA (NCT00803621)
- Testing
- Toxoplasma PCR assay
- Where
- 5 sites in France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Limoges
HIV Infection, AIDS
Once Daily 3TC, Efavirenz and ddI for HIV Infection
Poor compliance is thought to be a major cause of treatment failure. The TEddI study is a randomised, multi-centre, open-label study in well-controlled treatment-experienced HIV-infected patients to assess compliance with a…
- Trial name
- NCT00214435
- Testing
- once daily minimum 3-drug regimen of anti-retroviral medications
- Where
- Australia
- Volunteers
- 120 people
- Sponsor
- 407 Doctors
HIV/AIDS
A Peer-Led Intervention to Improve Postpartum Retention in HIV Care
The purpose of this study is to test the efficacy of a theory-driven peer intervention for pregnant and postpartum women living HIV.
- Trial name
- NCT04168008
- Testing
- WISH Adherence, WISH Parenting
- Where
- 7 sites in United States
- Volunteers
- 151 people
- Sponsor
- University of Pennsylvania
Infection, Human Immunodeficiency Virus
Single Dose Escalation Study of GSK2838232 in Healthy Subjects
GSK2838232 is a novel human immune virus (HIV) maturation inhibitor being developed for the treatment of chronic HIV infection. This study is the first administration of GSK2838232 in humans to establish the initial safety…
- Trial name
- NCT01802918
- Testing
- GSK2838232, Ritonavir
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV Infections
Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at Birth
The purpose of this study is to compare the effects of anti-HIV drug courses of different lengths in infants who became HIV infected at birth.
- Trial name
- NCT00102960
- Testing
- Abacavir sulfate, Didanosine, Efavirenz
- Volunteers
- 377 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Human Papillomavirus Infection
Screening for HPV and Cervical Cancer in Young Women With Perinatally Acquired HIV
This is a cross-sectional, observational study of high-risk HPV status, cervical cytology and HPV vaccine uptake and response in young women with perinatally acquired HIV.
- Conditions
- HIV Infections, Human Papillomavirus Infection, Cervical Cancer
- Trial name
- SHiP (NCT04587050)
- Testing
- Human papillomavirus testing, Cervical cytology, HPV serology
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- Imperial College London
Substance-Related Disorders, Human Immunodeficiency Virus
HIV & Drug Abuse Prevention for South African Men
The purpose of this study is to test the efficacy of randomizing all young men in a neighborhood to receive: 1) soccer training; 2) soccer and vocational training; or 3) a control condition, as a means to engage young men in HIV…
- Conditions
- Substance-Related Disorders, Human Immunodeficiency Virus, Alcoholism
- Trial name
- NCT02358226
- Testing
- Soccer League (SL), Soccer League/Vocational Training (SL-V)
- Where
- South Africa
- Volunteers
- 1,211 people
- Sponsor
- University of California, Los Angeles
HIV/AIDS, STD
Addressing the Continuum of Care Among High-risk Thai Men
Young Thai men who have sex with men (YMSM) are at high risk for HIV. However, the Thailand National HIV Strategy does not adequately cover HIV prevention for YMSM using specific methods relevant to them, and instead uses a…
- Trial name
- NCT05161689
- Testing
- HUG-M+
- Where
- 2 sites in Thailand
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Mahidol University
High Risk for HIV
Zambia SiVET MMR Tdap-IPV
Participants will receive vaccination for measles, mumps, and rubella (MMR) and tetanus, diphtheria, pertussis, and inactivated polio (Tdap-IPV).
- Trial name
- SiVET (NCT02589678)
- Testing
- Tdap - IPV Vaccine, MMR Vaccine
- Where
- 2 sites in Zambia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Emory University
Human Immunodeficiency Virus (HIV)
Regular HIV Testing Among At-Risk Latino Men
Early HIV diagnosis followed by linkage to treatment soon after HIV infection can reduce mortality and prevent new HIV infections.
- Trial name
- NCT02454725
- Testing
- Social Network, Comparison
- Volunteers
- 107 people
- Sponsor
- Medical College of Wisconsin
Hiv
Exploring a Digital HIV Onward Disclosure Intervention, in People Living With HIV of Sub-Saharan African Ethnicity.
Research has shown that people living with HIV struggle to disclose their HIV status to others, (a process known as self-disclosure or onward disclosure) due to associated challenges, including fear of discrimination from others.
- Trial name
- NCT05804968
- Testing
- Digital HIV Self Disclosure Intervention
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Royal Holloway University
Healthy Subjects, Infection, Human Immunodeficiency Virus
GSK1349572 Drug Interaction Study With Protease Inhibitors
A study in healthy volunteers to determine whether there is a drug interaction between GSK1349572 and the HIV protease inhibitors lopinavir/ritonavir and darunavir/ritonavir
- Trial name
- NCT00774735
- Testing
- GSK1349572
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hiv, Contraception Behavior
TwySHE - An Mhealth Peer-navigator Intervention to Increase PrEP and Contraceptive Use
The goal of this clinical trial is to learn if the TwySHE intervention can increase the use of HIV prevention in at-risk female university students aged 18-24 in Zambia.
- Trial name
- NCT06852508
- Testing
- TwySHE
- Where
- Zambia
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Methamphetamine Abuse, HIV
Theory-based Text Messaging to Reduce Methamphetamine Use and HIV Risks Among MSM
Participants receive culturally relevant and specifically tailored text messages based on the behavioral change theoretical constructs of Social Support Theory, Health Belief Model, and Social Cognitive Theory.
- Trial name
- NCT02008526
- Testing
- Text Messages Transmitted by Peer Health Educators (TXT-PHE), Text Messages Transmitted by Automation (TXT-Auto)
- Where
- United States
- Volunteers
- 286 people
- Sponsor
- Friends Research Institute, Inc.
Infection, Human Immunodeficiency Virus
Single-dose Pharmacokinetics of BMS-626529, Administered as BMS-663068, in Subjects With Hepatic Impairment Compared to Healthy Subjects
A single oral dose study in subjects with hepatic impairment and healthy control subjects. Subjects will stay at the clinical facility where interval blood samplings will be obtained and examined for drug effect.
- Trial name
- NCT02467335
- Testing
- BMS-663068
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
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