Clinical trials: Actinic Lesion
Oral Squamous Cell Carcinoma, Oral Potentially Malignant Disorder
SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography
This clinical trial aims to assess the efficacy of Optical Coherence Tomography (OCT) in the early diagnosis of oral cancer. It focuses on Oral Potentially Malignant Disorders (OPMDs) as precursors to Oral Squamous Cell Carcinoma…
- Conditions
- Oral Squamous Cell Carcinoma, Oral Potentially Malignant Disorder, Oral Leukoplakia, Proliferative Verrucous Leukoplakia
- Trial name
- SYMILIS OCT (NCT06321003)
- Testing
- OCT (Optical Coherence Tomography)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Palermo
Cutaneous Squamous Cell Carcinoma, Basal Cell Carcinomas
Study of Metabolic Changes in the Transformation Malignant Precancerous Skin Lesions
Skin carcinomas are the most frequent cancers in the world, including basal cell carcinomas and cutaneous squamous cell carcinoma (cSCCs), with more than 60.000 new annual cases in France.
- Trial name
- MITOSKIN (NCT04389112)
- Testing
- biopsy
- Where
- France
- Volunteers
- 119 people
- Sponsor
- University Hospital, Bordeaux
Actinic Keratosis
Actinic Keratosis Study
The main purpose of this study is to determine the effectiveness of a new combination therapy for actinic keratosis. This study investigates a new indication for an FDA-approved topical medication, calcipotriol, for treatment of…
- Trial name
- AK (NCT02019355)
- Testing
- 5-fluorouracil 5% cream, Calcipotriol 0.005% ointment, Vaseline
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Washington University School of Medicine
Actinic Keratosis
Development and Validation of a Quality of Life Instrument for Actinic Keratosis
Actinic keratoses (AKs) are some of the most common lesions seen by dermatologists. Flesh colored to erythematous, these lesions often present with scaling or crusting in sun damaged regions of the body.
- Trial name
- AKRQ (NCT01444989)
- Testing
- AKRQ questionnaire, Skindex-16, DLQI, Skin Health Calculator
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Actinic Keratoses, Carcinoma, Squamous Cell
Phase II AK Study in Organ Transplant Patients
The purpose of this study is to determine whether afamelanotide (CUV1647) is effective in reducing the number of actinic keratoses and squamous cell carcinomas developing in immune compromised organ transplant recipients, who are…
- Conditions
- Actinic Keratoses, Carcinoma, Squamous Cell, Organ Transplant Recipients
- Trial name
- NCT00829192
- Testing
- Afamelanotide (CUV1647)
- Where
- 12 sites in Australia, Belgium and 5 more
- Volunteers
- 200 people
- Sponsor
- Clinuvel Pharmaceuticals Limited
Actinic Cheilitis, Squamous Cell Carcinoma In-situ (SCC-is)
Photodynamic Therapy to Treat Actinic Damage in Patients With Squamous Cell Carcinoma (SCC) of the Lip
Our study is designed to evaluate the efficacy of photodynamic therapy (PDT) for treatment of actinic cheilitis (AC) and as an adjunct to Mohs surgery for squamous cell carcinoma (SCC) on the lips.
- Conditions
- Actinic Cheilitis, Squamous Cell Carcinoma In-situ (SCC-is), Squamous Cell Carcinoma (SCC), Photodynamic Therapy (PDT)
- Trial name
- NCT00868088
- Testing
- PDT prior to Mohs surgery
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Tufts Medical Center
Actinic Keratosis
Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis
To compare the safety and efficacy profiles of AM001 Cream, 7.5% and its vehicle cream in the treatment of Actinic Keratosis (AK) Lesions
- Trial name
- NCT03210740
- Testing
- AM001 Cream, 7.5%, Vehicle Cream
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- AmDerma
Actinic Keratosis
A Clinical Study to Evaluate the Sensitizing Potential of LEO 43204 Gel
This is a randomized, single-center, controlled, within-subject comparison study assessing the sensitization potential of the investigational product, LEO 43204 gel under open conditions in healthy volunteers.
- Trial name
- NCT02650505
- Testing
- LEO 43204, LEO 43204 Vehicle
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Actinic Keratosis
Efficacy Study & Safety Evaluation of SR-T100 Gel in Actinic Keratosis Treatment
Studies of SR-T100 gel and its clinical relevance in the treatment of AK, providing adequate measured outcomes for skin lesion treatment.
- Trial name
- NCT01493921
- Testing
- SR-T100 gel, Vehicle gel
- Where
- 6 sites in Taiwan
- Volunteers
- 113 people
- Sponsor
- G&E Herbal Biotechnology Co., LTD