Clinical trials: Active Surveillance
Eustachian Tube Dysfunction
Eustachian Tube Dysfunction Assessment
The purpose of the study is to understand the exact mechanism of the activity of paratubal muscles in opening eustachian tube in patients with the functional eustachian tube and those with the eustachian tube dysfunction problem.
- Trial name
- ETDA (NCT02667301)
- Testing
- EMG recording, Tympanic Cavity Air Exchange Test, Tympanometer test
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Stratejik Yenilikci Girisimler Ltd.
Arterial Thromboembolism, Venous Thromboembolism
Long-term Active Surveillance Study for Oral Contraceptives (LASS)
The objective of this study is to characterize and compare the risks of long-term use of oral contraceptives containing drospirenone and of other established oral contraceptives.
- Conditions
- Arterial Thromboembolism, Venous Thromboembolism, Breast Cancer
- Trial name
- NCT00676065
- Where
- Germany
- Volunteers
- 58,303 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Contraception
Transatlantic Active Surveillance on Cardiovascular Safety of NuvaRing (TASC)
The objective of this study is to characterize and compare the risks of short- and long-term use of NuvaRing® with marketed combined oral contraceptives.
- Trial name
- TASC (NCT00524771)
- Where
- Germany
- Volunteers
- 34,100 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Ductal Carcinoma in Situ
Acceptability of Active Monitoring (AM) as a Treatment Option for Ductal Carcinoma in Situ (DCIS)
The purpose of this research study is to evaluate a decision support tool for patients diagnosed with ductal carcinoma in situ (DCIS).
- Trial name
- NCT03775213
- Testing
- Decision Support Tool with Active Monitoring, Decision Support Tool without Active Monitoring
- Where
- United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Duke University
Low Blood Pressure, Blood Pressure
MediBeat - HeartBeat Observation Trial
The goal of the study was to compare the current gold standard blood pressure instrument (a mercury-filled sphygmomanometer with cuff and stethoscope) with the new experimental algorithm developed by HeartBeat Technologies Ltd.
- Conditions
- Low Blood Pressure, Blood Pressure, High Blood Pressure, Hypertension
- Trial name
- NCT04082819
- Testing
- Contec CMS50EW, Sphygmomanometer
- Where
- Canada
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- SE Health
Pain
The Use of Jet Injection Lidocaine for Blood Draws in Young Children
This study looks at the use of Jet Injection Lidocaine (J tip) for pain during blood draws in children ages 6 and younger. The investigators will use video observation of patients to asses their pain during lab draws using either…
- Trial name
- NCT01890642
- Testing
- J tip, Pain Ease Spray, 1% buffered lidocaine
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Maternal Depression and Parent Practices, Postpartum, Infant Development
Reducing Maternal Depression and Promoting Infant Social-Emotional Health & Development
A mobile remote coaching program study to improve maternal mood and increase parenting practices that lead to better infant social-emotional and communication outcomes
- Trial name
- MBN (NCT03464630)
- Testing
- Mom & Baby Net, Depression & Developmental Awareness System
- Where
- United States
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Georgia State University
HIV Positive, Ageing
The Effects of Ageing on the 'Pharmacokinetic and Clinical Observations in People Over Fifty'
The purpose of this study is to identify medical conditions that may cause particular problems to individuals receiving care for HIV infection over the age of 50.
- Trial name
- POPPY (NCT01737047)
- Where
- 8 sites in Ireland, United Kingdom
- Volunteers
- 1,377 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Patient Safety, Manipulation, Spinal
(MIST1)-Part 1: Assessment & Feasibility of Post-Symptoms Evaluation
To increase patient safety culture in spinal manipulation therapy (SMT) this study will assess the ability to implement an active surveillance reporting system for a chiropractic teaching clinic and determining preliminary…
- Trial name
- MIST1 (NCT03412097)
- Testing
- active surveillance
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Parker University
Contraception
International Active Surveillance Study of Women Taking Oral Contraceptives (INAS-OC)
The study compares the short- and long-term risks of a 24-day regimen of a drospirenone-containing oral contraceptive with the risks of established oral contraceptives in a study population that is representative for the actual…
- Trial name
- NCT00335257
- Where
- Germany
- Volunteers
- 85,109 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
HIV Infections
Automated Medication Platform With Video Observation and Facial Recognition to Improve Adherence to Antiretroviral Therapy in Patients With HIV/AIDS
This is a 90-day medication adherence study testing the HiDO is an automated AI-driven direct observation medication adherence platform, which is a 510K-exempt, Class I medical device with 24 people with HIV/AIDS, ages 18 to 55…
- Trial name
- NCT05454514
- Testing
- HiDO medication adherence platform, Automated Medication Platform with Video Observation, Time on Task
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Charles Gellman
Menorrhagia
Copper IUD Treatment Observation Study
Studies indicate that bleeding irregularities and dysmenorrhea are common reasons for copper IUD method discontinuation. Some evidence suggests that non-steroidal anti-inflammatory medications (NSAIDs) can help improve bleeding…
- Trial name
- CITROS (NCT02519231)
- Testing
- Naproxen
- Where
- 5 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Washington
Influenza, Vaccines Adverse Reaction
Surveillance for Adverse Events Following Influenza Immunization
Influenza vaccines are continuously modified to adjust to the virus antigenic shifts or drifts, and its safety profile may vary.
- Trial name
- NCT01318876
- Where
- 7 sites in Canada
- Volunteers
- 7,645 people, healthy volunteers welcome
- Sponsor
- PHAC/CIHR Influenza Research Network
Childhood Obesity
Painted Playgrounds Aim 1
Painted Playgrounds Aim 1: Observation will examine the physical environment of licensed childcare centers before and after painting stencil activities (hopscotch, foursquare, fun trails, etc.) on playgrounds.
- Trial name
- NCT03890913
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Intrauterine Growth Retardation
Randomized Clinical Trial: Expectant Management vs Laser Treatment of Monochorionic Twins With Severe Selective Intrauterine Growth Retardation and Absent or Reverse Diastolic Flow in the Umbilical Artery
Intrauterine growth retardation (IUGR) occurs in approximately 3 to 10% of singleton pregnancies, in 9.1% of all twins and 9.9% of monochorionic twins.
- Trial name
- NCT01177553
- Testing
- selective laser photocoagulation of communicating vessels, Expected Management
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Contraception
European Active Surveillance Study (EURAS)
EURAS is a multi-national, controlled, prospective, post-marketing, non-intervention cohort study of new users of drospirenone/ethinylestradiol (DRSP/EE), levonorgestrel/ethinylestradiol (LNG/EE) and other oral contraceptives…
- Trial name
- NCT00302848
- Testing
- Drospirenone, Levonorgestrel, Other progestin containing oral contraceptive
- Where
- Germany
- Volunteers
- 59,510 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Uterine Perforation
European Active Surveillance Study for Intrauterine Devices
The primary objective of the study is to assess the risks of intrauterine device (IUD) use in a study population that is representative for the actual users of the individual IUDs.
- Trial name
- EURAS-IUD (NCT00461175)
- Where
- Germany
- Volunteers
- 63,194 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany