Clinical trials: Active Surveillance
Nonmalignant Neoplasm, Prostate Cancer
MRI and Magnetic Resonance Spectroscopy Imaging in Patients Receiving Dutasteride for Benign Prostatic Hypertrophy and Low-Risk Prostate Cancer
RATIONALE: Diagnostic procedures, such as MRI and magnetic resonance spectroscopy imaging, may help in learning how well dutasteride works in patients with benign prostatic hypertrophy and low-risk prostate cancer.
- Trial name
- NCT00706966
- Testing
- dutasteride
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Medical Induction of Labor Affecting Newborn
Premature Rupture of Membranes With a Bishop Score<6: Comparison of Medical Induction/Expectant Management
The study is intended to compare expectant management and on presentation labor induction in women with premature rupture of membranes. The means of labor induction and cervical ripening are either oxytocin or dinoprostone.
- Trial name
- NCT02825641
- Testing
- Oxytocin, Dinoprostone
- Where
- Israel
- Volunteers
- 458 people
- Sponsor
- Rambam Health Care Campus
Observation, Postoperative
Proteomics and Physiological Parameters Predicting Complications After Colorectal Cancer Surgery
Study combines physiological data from wearables, continuous glucose montiors and proteomics to better assess risk of complications after colorectal surgery
- Trial name
- ProComp (NCT07494669)
- Testing
- Risk stratification with proteomics and data from wearables and CGMs
- Volunteers
- 210 people
- Sponsor
- Region Skane
OSAHS, Gastrointestinal Endoscopy
Observation of Clinical Effect of New Oropharyngeal Airway in Patients With OSHAS During Painless Gastroenteroscopy
the(obstructivesleepapneahypoapneasyndromeOSAHS) is a kind of to sleep appear periodically in the process of syndrome characterized by partial or complete obstruction of upper respiratory tract.Patients with obstruction during…
- Conditions
- OSAHS, Gastrointestinal Endoscopy, Airway Complication of Anesthesia
- Trial name
- NCT06594380
- Testing
- Group using new oropharyngeal airway (experimental group), Endoscopic bite group (control group)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Hypertension
Observation of Therapy With Micardis® (Telmisartan) in Patients With Essential Hypertension in Hospitals
The aim of the observational study was to supplement the data on efficacy, safety and tolerability of telmisartan under daily conditions in hospitals
- Trial name
- NCT02238262
- Testing
- Telmisartan
- Volunteers
- 2,318 people
- Sponsor
- Boehringer Ingelheim
Ovarian Neoplasms
Mo-Rez in First- Line (1L) Maintenance Treatment of Non-Homologous Recombination Deficient Ovarian Cancer (Non-HRd OC) [BEHOLD-Ovarian03]
This study specifically aims to evaluate how well mocertatug rezetecan (Mo-Rez) alone or in combination with bevacizumab works in treating ovarian cancer compared to bevacizumab alone or active observation (AO).
- Trial name
- NCT07694427
- Testing
- Mocertatug rezetecan, Bevacizumab
- Where
- 2 sites in Argentina, Japan
- Volunteers
- 720 people
- Sponsor
- GlaxoSmithKline
Lymphocytic Leukemia, Chronic
A Study of MabThera (Rituximab) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia.
This single arm study will assess the efficacy and safety of MabThera + chlorambucil as induction therapy, followed in responders by maintenance therapy or observation in elderly patients with previously untreated chronic…
- Trial name
- NCT00738374
- Testing
- rituximab [MabThera/Rituxan], chlorambucil
- Where
- 20 sites in Italy
- Volunteers
- 97 people
- Sponsor
- Hoffmann-La Roche
Thyroid Cancer, Papillary Thyroid Carcinoma
Active Surveillance for Low-risk Papillary Thyroid Carcinoma
This is a multi-center, non-randomized, prospective observational cohort study aimed at establishing a cohort of low-risk papillary thyroid cancer patients with a maximum tumor diameter of 1.5 cm or less, consisting of an active…
- Trial name
- MAeSTro-EXP (NCT06261190)
- Where
- 4 sites in South Korea
- Volunteers
- 499 people
- Sponsor
- National Cancer Center, Korea
Bipolar Disorder
A Study of Olanzapine in Participants With Bipolar Disorder.
This study aimed to identify treatment patterns in patients with bipolar disorder receiving olanzapine according to demographic and clinical characteristics and to evaluate the effectiveness of education on weight gain, a side…
- Trial name
- NCT07263191
- Testing
- Olanzapine
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Elderly (People Aged 65 or More)
Acute Effects of Motor Imagery and Action Observation in the Elderly: Single-Blind Randomized Controlled Trial
The aim of this study is to investigate the effects of acute action observation, motor imagery, exercise, and combined exercise training on parameters such as balance, reaction time, flexibility, fear of falling, cognitive…
- Trial name
- NCT07016061
- Testing
- Motor İmagery Group, Action Observation Group, Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Melanoma
Neoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Nivolumab or Neoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Observation Compared With Adjuvant Nivolumab in Treatment-Naive High-risk Melanoma Participants
The purpose of this study is to evaluate the role of neoadjuvant immunotherapy and to demonstrate high pathologic complete response (pCR) and near pCR rates in melanoma participants with clinically detectable nodal disease and a…
- Trial name
- CheckMate 7UA (NCT04495010)
- Testing
- Nivolumab, Ipilimumab
- Where
- 118 sites in United States, Australia and 14 more
- Sponsor
- Bristol-Myers Squibb
Immune System Diseases, COVID-19 Vaccine Adverse Reaction
COVID-19 Post-Vaccination Observation
The study started after the second COVID-19 vaccination of the participant with blood spots appearing on the skin with severe arthritis.
- Conditions
- Immune System Diseases, COVID-19 Vaccine Adverse Reaction, Immune System Disorder
- Trial name
- NCT06107348
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Yang I. Pachankis, PhD
Sexual Disorder, Physiological
"Evolution of Sexual Symptoms in Paraphilic Sexual Offenders With/Without Antiandrogen or SSRI Treatment"
The ESPARA study is a multicenter observational research project aiming to monitor, over a three-year period, the evolution of sexual symptoms in male sexual offenders with paraphilia, divided into three groups: receiving…
- Trial name
- ESPARA (NCT07144943)
- Testing
- For subjects on SSRIs: bone densitometry
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier St Anne
Dyspnea and Respiratory Insufficiency in Children
Multidimensional Characterization of Dyspnea in Children
There is no specific tool existing to describe dyspnea in children in a multidimensional way. It has been shown in adult studies that multidimensional dyspnea evaluation scales are well correlated to quality of life and…
- Trial name
- DYSPED (NCT05500833)
- Testing
- Multidimentional observation scale (MDP)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bladder Outlet Obstruction
Bladder Outlet Obstruction Observation Using Dynamic Urine Vibration "Holter"
Current gold standard of bladder outlet diagnosis is pressure flow study. This study is invasive time consuming and requires expensive and complex set-up.
- Trial name
- NCT01779349
- Testing
- Dynamic Urine Vibration "Holter"
- Where
- 2 sites in Israel
- Volunteers
- 45 people
- Sponsor
- P. Square Medical Ltd
HIV Prevention
Are Louisiana Pharmacists PrEPared? Implementing Training and an Active PrEP (Pre-Exposure Prophylaxis) Prescribing Surveillance Program
Though broadening PrEP (Pre-Exposure Prophylaxis) availability to Louisiana pharmacies addresses key access issues for Louisiana's population, there is no current baseline data which explore current pharmacist and pharmacies'…
- Trial name
- NCT06530225
- Testing
- Education and Mentoring for Prescribing Pharmacists
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Xavier University of Louisiana.
Rectal Cancer
Watchful Waiting. An Observational Study of Patients With Rectal Cancer After Concomitant Radiation and Chemotherapy
The purpose of this study is to investigate if operation and permanent stoma can be omitted in patients with cancer in the lower part of the rectum.
- Trial name
- NCT00952926
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Vejle Hospital
Non ST-elevation Myocardial Infarction
Impact of Time to Coronary Angiography on Survival for NSTEMI
This study aims to investigate the extent to which the time to angiography impacts on survival in patients hospitalised with NSTEMI.
- Trial name
- NCT02693015
- Volunteers
- 235,986 people
- Sponsor
- University of Leeds
Chronic Heart Failure, Acute Decompensated Heart Failure
Therapy Adjustment and IndividuaLized Response With Biomarker Observation in ReaL-world Heart Failure
The goal of TAILOR-HF is to integrate clinical data, laboratory parameters, treatment patterns, and circulating biomarkers to identify factors that predict individual response to pharmacological treatment in patients with heart…
- Trial name
- TAILOR-HF (NCT07647848)
- Volunteers
- 600 people
- Sponsor
- Maastricht University Medical Center
Articular Cartilage Defects of Knee
Observation of the Result After Chondron (Autologous Chondrocytes) Treatment
This investigator-sponsored trial attempts to evaluate the effectiveness of Chondron transplantation by tracking subjects who had the Chondron implantation to observe effectiveness.
- Trial name
- NCT01056900
- Testing
- Autologous Chondrocyte Implantation
- Where
- South Korea
- Volunteers
- 127 people
- Sponsor
- Cellontech Co., Ltd.