Clinical trials: Active Surveillance
Deglutition Disorders
Effect and Complication of Two Types of Nasogastric Tube Feeding for Elderly Dysphagia Patient After Stroke
Dysphagia is a common problem after stroke.Patients after stroke with swallow problem will have a nasogastric tube to be feeded. In this study , investigators have including and excluding criteria.
- Trial name
- NCT03844139
- Testing
- Feeding pump and glycerin syringe
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Active Surveillance, Clear Cell Renal Cell Carcinoma
Belzutifan's Role in Active Surveillance Versus Treatment for Indolentmetastatic Clear Cell Renal Ccell Carcinoma (BRAVE-RCC)
To learn if belzutifan can help to control the disease in patients with metastatic RCC who are considered candidates for active surveillance and have not undergone previous systemic treatment.
- Trial name
- NCT07023432
- Testing
- Belzutifan, Active Surveillance
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- M.D. Anderson Cancer Center
Sickle Cell Anemia
Sparing Conversion to Abnormal TCD (Transcranial Doppler) Elevation (SCATE)
The primary goal of the Phase III SCATE trial is to compare 30 months of alternative therapy (hydroxyurea) to standard care (observation) in children with sickle cell anemia and conditional (170 - 199cm/sec) Transcranial Doppler…
- Trial name
- SCATE (NCT01531387)
- Testing
- Hydroxyurea
- Where
- 3 sites in United States, Brazil and 1 more
- Volunteers
- 38 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Thyroid Nodule
Active Surveillance Program in Thyroid Nodules
Overview This study focuses on thyroid nodules, specifically the Bethesda IV-VI categories, which have uncertain or suspicious malignancy.
- Trial name
- NCT06653257
- Testing
- Active surveillance
- Where
- 4 sites in Colombia
- Volunteers
- 300 people
- Sponsor
- Centro de Excelencia en Enfermedades de Cabeza y Cuello
Prostate Cancer, Prostate Adenocarcinoma
Active Surveillance for Low Risk Prostate Cancer
An active surveillance protocol for patients diagnosed low-risk prostate cancer will be held. We plan to use PSA (prostate-specific antigen) testing, DRE (digital rectal examination), TRUS (transrectal ultrasound), MRI (magnetic…
- Trial name
- NCT04146077
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Prostate Cancer, Active Surveillance for Prostate Cancer
Micro-Ultrasound for Detecting Clinically Significant Prostate Cancer in Active Surveillance
Active surveillance is a common approach for men with low-risk or favorable intermediate-risk prostate cancer, aimed at avoiding or delaying treatment while closely monitoring the disease.
- Conditions
- Prostate Cancer, Active Surveillance for Prostate Cancer, Imaging Techniques
- Trial name
- MUS-AS (NCT07386171)
- Testing
- Micro-Ultrasound (mUS)
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Observation
Investigating the Relationship Between Parents and Their Children With ADHD and Conduct Disorder
This study aims to uncover mechanisms of action underlying any long-term change in youth antisocial behavior by considering the role of child and family characteristics as mediators and moderators of change.
- Trial name
- NCT03691389
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yale-NUS College
Adverse Reaction to Other Drugs and Medicines
5-HT3 Antagonists (Antiemetics) and Cardiac Safety
5-HT3 antagonists (ondansetron) are highly effective medications for the treatment of nausea and vomiting. However, these medications also associated with potentially severe and life-threatening cardiac adverse drug reactions…
- Trial name
- NCT02436798
- Testing
- Ondansetron
- Where
- Canada
- Volunteers
- 266 people
- Sponsor
- University of British Columbia
Abdominal Aortic Aneurysms
Talent Converter Post-Approval Study
The primary endpoint is successful secondary endovascular treatment with the Talent Converter stent graft of subjects having received prior endovascular repair of infrarenal abdominal aortic or aortoiliac aneurysms using the…
- Trial name
- NCT01129609
- Testing
- Talent Converter Stent Graft and Talent Occluder with Occluder Delivery System
- Volunteers
- 20 people
- Sponsor
- Medtronic Cardiovascular
Oligometastatic Prostate Cancer (OMPC)
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
The purpose of this study is to evaluate the efficacy and safety of lutetium (177Lu) vipivotide tetraxetan (AAA617) in participants with oligometastatic prostate cancer (OMPC) progressing after definitive therapy to their primary…
- Trial name
- PSMA-DC (NCT05939414)
- Testing
- AAA617, piflufolastat (18F), gallium (68Ga) gozetotide (25μg)
- Where
- 144 sites in United States, Argentina and 25 more
- Volunteers
- 450 people
- Sponsor
- Novartis Pharmaceuticals
HIV, Coronary Artery Disease
Metformin for HIV Inflammation
This proposal seeks to assess the impact of 24 weeks of metformin on non-calcified plaques and calcified plaques assessed by coronary CT angiography, and on whether these changes can be explained by metformin-induced phenotypic…
- Trial name
- NCT02383563
- Testing
- metformin extended release
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Hawaii
Intubation, Intratracheal
Observation of the Pressure Changes of the Endotracheal Tube Cuff in the Head and Neck Surgery Under General Anesthesia
Endotracheal tube is a commonly used for general anesthesia in head and neck surgery. It is necessary to place the endotracheal tube in the trachea of the patient and then inflate the cuff with air.
- Trial name
- NCT03938493
- Testing
- monitoring of the endotracheal tube cuff
- Where
- South Korea
- Volunteers
- 201 people
- Sponsor
- Yonsei University
Autism Spectrum Disorder, Global Developmental Delay
Reliability and Validity of CCISO for Diagnosis of Autism Spectrum Disorder
The investigators designed the Child-Caregiver Interaction Observation Scale（CCIOS）to assess social communication behaviors, stereotyped behaviors for children with autism spectrum disorder(ASD) via a 20-min video of interactions…
- Conditions
- Autism Spectrum Disorder, Global Developmental Delay, Language Disorder
- Trial name
- NCT04511767
- Testing
- Do not take any interventions
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Children's Hospital of Fudan University
Basal Cell Carcinoma
A Study of Observation and Follow-up in People With Basal Cell Carcinoma
The purpose of this study is to find out more about how Basal Cell Carcimonas/BCCs grow and to learn more effective ways to monitor and treat these common cancers.
- Trial name
- NCT05473507
- Testing
- Digital Dermoscopy, Reflectance confocal microscopy (RCM), Optical coherence tomography (OCT)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hand
Investigation of the Effect of Combined Motor Imagery and Activity Observation Therapy on Strengthening the Non-Dominant Hand in Healthy Individuals
Introduction: Motor Imagery (MI) and Action Observation (AO) are well-established cognitive training techniques that activate neural networks similar to those involved in actual motor execution.
- Trial name
- NCT07235449
- Testing
- Conservative treatment + Motor imagery program, Conservative treatment + Motor imagery and action observation program, Conservative treatment via strengthening exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
PREGNANCY
Induction Versus Expectant Management With Abnormal Maternal Biochemical Markers
Induction of labor at term versus expectant management among women with abnormal maternal biochemical markers. A randomized controlled trial
- Trial name
- NCT02754635
- Testing
- Induction of labour, Expectant management
- Where
- Israel
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Bell Palsy
Comparative Effects of Mime Therapy and Action Observation Therapy in Bell's Palsy
The aim of this study is to determine comparative effects of mime therapy and action observation therapy on facial symmetry and quality of life in Bell's palsy.
- Trial name
- NCT06308250
- Testing
- MIME THERAPY, ACTION OBSERVATION THERAPY
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Riphah International University
Stroke
Finding Atrial Fibrillation in Patients With Unexplained Stroke Using Longterm Cardiac Monitoring
The SURPRISE study investigates atrial fibrillation(AFIB) in patients with a previous unexplained stroke. It uses long term monitoring of the heart of up to three years, searching for paroxysmal atrial fibrillation(PAF) otherwise…
- Trial name
- SURPRISE (NCT01498146)
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- Bispebjerg Hospital
Androgenic Alopecia
A Clinical Observation of 1565nm Non-ablative Fractional Laser in the Treatment of Androgenic Alopecia
1. Androgenic alopecia (AGA) is a clinically common non cicatricial, progressive hair follicle microminiaturization disorder that begins in puberty or after puberty.
- Trial name
- NCT05827991
- Testing
- 1565nm Non-ablative Fractional Laser, 5% minoxidil external use, 1565nm Non-ablative Fractional Laser combined with 5% minoxidil
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Xijing Hospital
Warm Needling, Electroacupuncture
Clinical Observation of Warm Needling Combined With and Electroacupuncture Therapy on Ovulatory Dysfunction
To observe the effect of warm needling combined with electroacupuncture on the ovulation promotion rate and pregnancy rate in luteinized unruptured follicle syndrome (LUFS).
- Conditions
- Warm Needling, Electroacupuncture, Ovulation Dysfunction
- Trial name
- NCT05874518
- Testing
- warm needling combined with electroacupuncture, The treatment with letrozole tablets was started on the fifth day of the menstrual cycle
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Liuzhou Maternity and Child Healthcare Hospital