Clinical trials: Active Surveillance for Prostate Cancer
Prostate Cancer
European Multicenter Validation of PCaVision: A Head-to-Head Diagnostic Accuracy Study Comparing Multiparametric Transrectal Ultrasound to MRI for Clinically Significant Prostate Cancer Detection
The goal of this clinical trial is to learn if a new ultrasound-based imaging method (PCaVision) can accurately detect clinically significant prostate cancer in adult men (18 years and older) who are either undergoing initial…
- Trial name
- PCaVISTA (NCT06935487)
- Testing
- transrectal ultrasound of prostate (TRUS) with AI software algorithm, MRI prostate
- Where
- 10 sites in France, Germany and 4 more
- Volunteers
- 806 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Low-Risk Prostate Cancer
Biological Markers and Advanced Imaging for Prostate Cancer Progression in Active Surveillance
This study aims to identify patients with low-risk prostate cancer (ISUP Grade Group 1) eligible for active surveillance who are at higher risk of upgrading to ISUP Grade Group 2 or higher at confirmatory biopsy one year after…
- Trial name
- PSMA-AS (NCT06866041)
- Testing
- mpMRI-targeted confirmatory biopsy
- Where
- Italy
- Volunteers
- 74 people
- Sponsor
- Università Vita-Salute San Raffaele
Prostate Cancer
Randomized Controlled Trial of CAN-2409 Immunotherapy During Active Surveillance for Prostate Cancer (ULYSSES)
The purpose of this study is to evaluate the effectiveness of CAN-2409 immunotherapy in patients undergoing active surveillance for localized prostate cancer.
- Trial name
- NCT02768363
- Testing
- aglatimagene besadenovec, valacyclovir
- Where
- 23 sites in United States, Mexico
- Volunteers
- 187 people
- Sponsor
- Candel Therapeutics, Inc.
Prostate Cancer
Effects of a Genistein Concentrated Polysaccharide (GCP) for Prostate Cancer on Active Surveillance.
Genistein Combined Polysaccharide (GCP) may play a role as a secondary chemopreventive agent in the treatment of localized prostate cancer.
- Trial name
- GCP (NCT00584532)
- Testing
- GCP - Genistein Combined Polysaccharide
- Volunteers
- 66 people
- Sponsor
- University of California, Davis
Prostate Cancer
Prognostic Factors in Prostate Cancer for Patients Treated by Watchful Waiting
The Trans-Atlantic Prostate Group (TAPG) was established to examine the hypothesis that through a detailed retrospective analysis of outcome in a group of men with clinically localised prostate cancer at diagnosis, variables such…
- Trial name
- TAPG (NCT03912883)
- Volunteers
- 3,350 people
- Sponsor
- Queen Mary University of London
Prostate Cancer
Dutasteride in Treating Patients With Prostate Cancer
RATIONALE: Dutasteride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This randomized phase II trial is studying how well giving dutasteride works in treating patients with…
- Trial name
- NCT01193855
- Testing
- dutasteride, gadolinium-chelate, active surveillance
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University College London Hospitals
Prostate Cancer
Correlative Analysis of the Genomics of Vitamin D and Omega-3 Fatty Acid Intake in Prostate Cancer
The purpose of this study is to see if eating vitamin D, omega 3 and turmeric (curcumin) slows the growth of prostate cancer in men on active surveillance.
- Trial name
- NCT03290417
- Testing
- Vitamin D, Omega-3, Turmeric
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Case Comprehensive Cancer Center