Clinical trials: Activity, Motor, open to volunteers
Acute Coronary Syndrome, Physical Inactivity
Positive Emotions Following Acute Cardiac Events
The focus of this study is to test the efficacy of a 12-week, remotely delivered, positive-psychology-motivational interviewing (PP-MI) intervention, with additional twice weekly text messages for a total of 24 weeks (with…
- Trial name
- PEACE-V (NCT05412862)
- Testing
- Positive Psychology + Motivational Interviewing
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Massachusetts General Hospital
Cervical Shortening
Routine Activity and Preterm Delivery Risk in Women With a Short Cervix
The goal of this clinical trial is to evaluate the effect of routine activity versus rest on the risk of preterm delivery in pregnant women with a short cervix diagnosed between 24 and 34 weeks of gestation.
- Trial name
- NCT06884761
- Testing
- Maximal Rest
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Wolfson Medical Center
Drug-Drug Interactions
Effect of Dexamethasone on CYP Enzyme Activity in Healthy Male Subjects
Purpose: The purpose of this study is to understand how dexamethasone affects the activity of drug-metabolizing enzymes in the body and how this may influence interactions with other medicines, such as voriconazole.
- Trial name
- NCT07426042
- Testing
- Dexamethasone, CYP Probe Cocktail, voriconazole
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Min Kyu Park
Inflammation, Oxydative Stress
Physical Activity Oxidative Stress and Inflammation With Ageing
Sarcopenia, an age-related decline in muscle function, are thought to be influenced by oxidative stress and low-grade inflammation, resulting in significant muscle mass reduction and altered physical performance.
- Conditions
- Inflammation, Oxydative Stress, Sarcopenia, Older Patient
- Trial name
- POXI-AGEING (NCT06980896)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Nantes University Hospital
Generalized Anxiety Disorder (GAD)
Inspiratory Muscle Training and Diaphragmatic Breathing in GAD
This study will compare inspiratory muscle training and diaphragmatic breathing exercises in individuals with generalized anxiety disorder (GAD).
- Trial name
- NCT07913503
- Testing
- Inspiratory Muscle Training, Diaphragmatic Breathing Exercises, Progressive Muscle Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Saglik Bilimleri Universitesi
All Health Backgrounds to Determine a Baseline of Flatus Activity
Using the Smart Underwear Device to Determine a Baseline of Flatus Activity Normalized to Fiber Intake
The goal of this observational study is to quantify the typical frequency of flatulence in healthy adults, normalized by fiber intake, using the Smart Underwear device.
- Trial name
- NCT07134543
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Affect and Exertion During and Post-exercise
Manipulating Exercise Intensity and Affective Responses for Cardiac Rehabilitation Program Acute Coronary Syndrome Patients
The goal of this clinical trial is to learn if pleasure-oriented exercise intensity manipulation increases physical activity (PA) behavior in patients who have suffered acute coronary syndrome during a cardiac rehabilitation…
- Trial name
- NCT07105943
- Testing
- Control, Experimental
- Where
- 2 sites in Portugal
- Volunteers
- 52 people
- Sponsor
- Instituto Politécnico de Leiria
Lung Cancer
PulmoSalud: Multimodal Program for Prehabilitation and Early Home Rehabilitation in Patients With Lung Cancer
Lung cancer remains a leading cause of morbidity and mortality, and resective surgery is the treatment of choice in operable stages.
- Trial name
- NCT07478276
- Testing
- Individualized pre-operative physical exercise, Post-operative rehabilitation physical exercise, Respiratory physiotherapy Prehabilitation
- Volunteers
- 84 people
- Sponsor
- FranciscoVeraSerrano
Pediatric Cancer, Pediatric Cancer Patients
Real World Pediatric Oncology Rehabilitation in Italy ( ReWori )
This observational study aims to describe changes in the functional abilities of children, adolescents and young adults with cancer who are undergoing physiotherapy or neuropsychomotor rehabilitation.
- Conditions
- Pediatric Cancer, Pediatric Cancer Patients, Pediatric Oncology, Rehabilitation
- Trial name
- REWORI (NCT07368582)
- Testing
- Rehabilitation intervention
- Where
- 13 sites in Italy
- Volunteers
- 249 people
- Sponsor
- Associazione Italiana Ematologia Oncologia Pediatrica
Cystic Fibrosis (CF), Fatigue
CF Wellness Program
This study is a pilot randomized control trial (RCT; N=80) comparing the Cystic Fibrosis Wellness Program (CFWP) to usual care (UC) to evaluate (1) Intervention Adherence (completion of the CFWP Coaching Sessions) (2) Study…
- Conditions
- Cystic Fibrosis (CF), Fatigue, Sleep Quality, Insomnia
- Trial name
- NCT07071324
- Testing
- CF Wellness Program
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Johns Hopkins University
Spinal Muscular Atrophy
Characterizing Perceived Physical Fatigability in Nusinersen-treated SMA
The purpose of this project is to investigate the utility of the SMA EFFORT, an SMA-specific patient-reported outcome measure, to assess perceived physical fatigability that is anchored to intensity and duration of activities.
- Trial name
- NCT06955897
- Testing
- Observational
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Columbia University
Stroke, Healthy
WIM Exosuit Wearable Soft Robot for Enhancing Walking Activity
This study is to develop, test, and optimize a soft hip wearable robot for individuals with stroke, Parkinson's, multiple sclerosis, or older adults with no neurologic deficits.
- Trial name
- NCT07061691
- Testing
- WIM Robotic Exoskeleton
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Esophageal Cancer, Gastric Cancer (Diagnosis)
Exercise Training After Upper Gastrointestinal Cancer Surgery
This randomized controlled trial aims to determine the optimal exercise intensity for improving postoperative recovery in patients with upper gastrointestinal cancer.
- Conditions
- Esophageal Cancer, Gastric Cancer (Diagnosis), Upper Gastrointestinal Cancer
- Trial name
- NCT07561840
- Testing
- High-Intensity Interval Training (HIIT), Low-Intensity Continuous Training (LICT)
- Where
- 2 sites in Japan
- Volunteers
- 171 people
- Sponsor
- Kansai Medical University
Physical Inactivity, Environmental Exposure
Reconstructing Schoolyards With Greenery to Increase Schoolchildren's Physical Activity and Mitigate Climate Changes
By reconstructing schoolyards with greenery, physical activity levels among children can be increased at the population level and also mitigate health and environmental risks resulting from rising climate changes in urban areas.
- Conditions
- Physical Inactivity, Environmental Exposure, Mental Health Wellness 1
- Trial name
- NCT05865782
- Testing
- Schoolyard reconstruction
- Where
- Sweden
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Multiple Myeloma
A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
Multiple myeloma (MM) is a plasma cell disease characterized by the growth of clonal plasma cells in the bone marrow. The purpose of this study is to assess the safety and change in disease activity of surzetoclax in adult…
- Trial name
- NCT06953960
- Testing
- Surzetoclax, Daratumumab, Dexamethasone
- Where
- 51 sites in United States, Australia and 10 more
- Volunteers
- 325 people
- Sponsor
- AbbVie
Depression / Major Depressive Disorder, Mood
Intern Health Study 2026
The aim of this study is to evaluate the efficacy of using a reinforcement learning algorithm to determine the optimal content of a mobile health intervention (message delivered via smartphone) for improving the mood, physical…
- Conditions
- Depression / Major Depressive Disorder, Mood, Sleep, Physical Activity
- Trial name
- IHS 2026 (NCT07685925)
- Testing
- Intern Health Study behavioral change mobile notification
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Alzheimer Disease, Physical Activity
Inspiring Seniors Towards Exercise Promotion to Protect Cognition
The goal of this clinical trial is to test the benefits of beat-accented music stimulation (BMS) for behavioral changes of physical activity (PA) in older adults with subjective memory complaints.
- Trial name
- iSTEP+ (NCT06496425)
- Testing
- Beat-accentuated, personalized music stimulation (BMS), Strength Training (ST), Aerobic exercise (AE)
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Emory University
Type 1 Diabetes Mellitus
Hypoglycemia Fear Affect Autonomic Function, Physical Activity, and Exercise Capacity in Type I Diabetes
This cross-sectional study aims to investigate whether fear of hypoglycemia affects autonomic function, physical activity levels, and exercise capacity in children and adolescents with T1DM.
- Trial name
- HypoFear-T1DM (NCT07527676)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Ordu University
Hypertension, Exercise Training
Reducing Heart Failure Risk in Late-Life With Physical Activity
The goal of this clinical trial is to learn about the molecular pathways associated with the benefit of a regular exercise program in patients with high blood pressure and who don't already participate in regular exercise.
- Conditions
- Hypertension, Exercise Training, Cardiac Rehabilitation, Proteomics
- Trial name
- NCT06247774
- Testing
- Cardiac Rehabilitation, Attention Control
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Behavior, Motor Activity
Physical Activity Trends in Cancer Survivors Treated at the 'MOvement and REhabilitation' Clinic
An active lifestyle after a cancer diagnosis can reduce the side effects of treatment and improve quality of life, mental health, and survival.
- Trial name
- MOREACTIVE2025 (NCT07373626)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
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