Clinical trials: Acute Calculous Cholecystitis
Acute Cholecystitis, Cholecystectomy
Laparoscopic Cholecystectomy for Acute Cholecystitis After 72 Hours of Symptoms
The purpose of this study is to compare the clinical outcomes of early versus delayed laparoscopic cholecystectomies for acute cholecystitis with more than 72 hours of symptoms.
- Trial name
- NCT01548339
- Testing
- Laparoscopic cholecystectomy
- Where
- Switzerland
- Volunteers
- 86 people
- Sponsor
- University of Lausanne Hospitals
Acute Cholecystitis, Colorectal Cancer
Safety and Feasibility of ActivSightTM in Human
ActivSightTM combines an innovative form factor and proprietary software to deliver precise, objective, real-time visualization of blood flow and tissue perfusion intraoperatively for laparoscope-based surgery.
- Conditions
- Acute Cholecystitis, Colorectal Cancer, Diverticulitis, Colonic, Obesity, Morbid
- Trial name
- NCT04633512
- Testing
- ActivSight
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Activ Surgical
Cholecystitis
Effect Of Early Versus Delayed Laparoscopic Cholecystectomy In Patients With Grade II Cholecystitis
The timing ofthe cholecystectomy in patients with acute cholecystitis is still controversial. In our study, we aimed toinvestigate the effect of early and delayed cholecystectomy on difficultcholecystectomy, morbidity and…
- Trial name
- NCT05352087
- Testing
- Laparoscopic cholecystectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Tepecik Training and Research Hospital
Cholecystitis, Acute, Gallbladder Neoplasms
EEG Parameters Between Remimazolam- and Propofol-based Anesthesia
This is an observational study comparing perioperative quantitative EEG parameters between the conventional propofol/remifentanil and remimazolam/remifentanil.
- Conditions
- Cholecystitis, Acute, Gallbladder Neoplasms, Acalculous Cholecystitis
- Trial name
- NCT06178848
- Testing
- propofol group, remimazolam group
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Acute Cholecystitis, Biliary Colic
Transient ECG Changes in Patients With Acute Biliary Disease
Background: The importance of ischemic ECG changes including St segment elevation, ST segment depression or T wave inversion that indicate myocardial ischemia are well established and require appropriate investigation and…
- Conditions
- Acute Cholecystitis, Biliary Colic, Acute Cholangitis
- Trial name
- NCT01706068
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Ziv Hospital
Acute Cholecystitis, Pain
Comparison of Morbidity After Laparoscopic Cholecystectomy for Acutely Inflamed Gall Bladder With and Without Drain
The purpose of this study was to compare the frequency of pain and mean hospital stay in patients with and without drain insertion, following laparoscopic cholecystectomy for acutely inflamed gallbladder.
- Conditions
- Acute Cholecystitis, Pain, Morbidity, Multiple, Surgery
- Trial name
- NCT04346550
- Testing
- Suction drain
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Shifa International Hospital
Acute Cholecystitis
The Comparison of Hemodynamic Effects Between Remimazolam-remifentanil and Propofol-remifentanil in Patients Undergoing Laparoscopic Cholecystectomy
This study is conducted to determine whether the occurrence of hypotension is reduced by the combined use of remimazolam and remifentanil compared to the conventional combination use of propofol and remifentanil.
- Trial name
- NCT05164159
- Testing
- propofol group, remimazolam group
- Where
- South Korea
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Frailty, Gallbladder Diseases
Frailty is a Risk Factor Postcholecystectomy
The goal of this observational study is to learn about the long-term effects of cholecystectomy in patients over the age of 60 who take cholecystectomy to treat their acute cholecystitis).
- Trial name
- NCT07696078
- Testing
- cholecystectomy open
- Sponsor
- Zagazig University
Drainage, Laparoscopic Cholecystectomy
The Efficacy and Safety of Using Prophylactic Abdominal Drainage After Cholecystectomy
Investigators want to assess the safety and efficacy of using abdominal drainage with not using any drainage, by estimating different outcomes after laparoscopic cholecystectomy for different reasons.
- Conditions
- Drainage, Laparoscopic Cholecystectomy, Acute Cholecystitis
- Trial name
- NCT05267860
- Testing
- Prophylactic Drain
- Where
- Syria
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Biliary Disease, Gallstone; Cholecystitis, Acute
Multicentric Point of Care UltraSound by Surgeons Trial
Acute gallbladder pathology and acute diverticulitis are common conditions met in emergency departments and comprise the bulk of admissions throughout general surgical calls.
- Conditions
- Biliary Disease, Gallstone; Cholecystitis, Acute, Diverticulitis, Colonic, Abscess Pelvic
- Trial name
- POCUSS (NCT02682368)
- Testing
- Point of Care Ultrasound by Surgeons (POCUSS), Radiology report, Surgery-Intra-operative findings
- Where
- 5 sites in Ireland, Italy and 2 more
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Connolly Hospital Blanchardstown
Gastric Outlet Obstruction, Biliary Obstruction
Prospective Registry Of Therapeutic EndoscopiC ulTrasound
This registry aims to analyze long-term outcomes of therapeutic EUS (T-EUS) procedures, as well as to describe clinical and technical variables potentially predicting clinical success or adverse events, for a better selection of…
- Conditions
- Gastric Outlet Obstruction, Biliary Obstruction, Acute Pancreatic Fluid Collection, Acute Pancreatitis With Infected Necrosis
- Trial name
- PROTECT (NCT04813055)
- Testing
- Therapeutic EUS, Percutaneous Procedures, Surgical Interventions
- Where
- Italy
- Volunteers
- 510 people
- Sponsor
- Paolo Giorgio Arcidiacono, MD
Pregnancy Complications, Acute Appendicitis
Fetal Outcomes Among Pregnant Emergency General Surgery Patients
Approximately 1 in 500 pregnant women require non-obstetric surgery. Surgical care for the pregnant woman raises concern for complications adversely affecting pregnancy outcomes.
- Conditions
- Pregnancy Complications, Acute Appendicitis, Acute Cholecystitis, Biliary Pancreatitis
- Trial name
- NCT05085353
- Testing
- non-obstetric acute general surgical disease
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Methodist Health System
Acute Cholecystitis
Primary EUS-GBD in Patients With Unresectable Malignant Biliary Obstruction and Cystic Duct Orifice Involvement.
to determine if primary prophylaxis with Endoscopic Ultrasound-Gallbladder Drainage (EUS-GBD) in unresectable cancer patients with the orifice of the cystic duct (OCD) involvement is superior to conservative management (Non…
- Trial name
- NCT03729882
- Testing
- EUS-guided gallbladder drainage, Non EUS-guided gallbladder drainage
- Where
- Ecuador
- Volunteers
- 22 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Acute Cholecystitis
Acute Cholecystitis: Early Versus Delayed Laparoscopic Cholecystectomy; Randomized Prospective Study
The best management of the acute cholecystitis is to do laparoscopic cholecystectomy. The hypothesis is that to do it as an early intervention after patient admission is better than delayed cholecystectomy regarding the hospital…
- Trial name
- NCT02130245
- Testing
- Early cholecystectomy, Delayed cholecystectomy
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Acute Cholecystitis
EUS-GBD vs Antibiotics for Patients at High Risk for Cholecystectomy
Objectives Acute cholecystitis commonly occurs in elderly patients who are at high-risk for surgery. Whether upfront Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is advantageous over antibiotics first for mild…
- Trial name
- NCT05893511
- Testing
- Endoscopic ultrasound-guided gallbladder drainage, Antibiotics first
- Where
- Hong Kong
- Volunteers
- 110 people
- Sponsor
- Chinese University of Hong Kong
Cholecystitis, Acute, Biliary Diseases
Repeat Biliary Point of Care Ultrasound for Detecting Early Acute Cholecystitis
The goal of this interventional, prospective study is to determine the clinical utility of a repeat point-of-care ultrasound of the gallbladder in adult emergency department patients with abdominal pain for which initial imaging…
- Trial name
- NCT07792200
- Testing
- Repeat biliary point of care ultrasound
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- WellSpan Health
Acute Calculous Cholecystitis
Complications in Acute Calculous Cholecystitis
Acute calculous cholecystitis (ACC) is the second most frequent surgical condition in emergency departments, the complication rate of ACC is 8-20%, and the mortality rate is 0.5-6% in recent series.
- Trial name
- NCT05135299
- Volunteers
- 963 people
- Sponsor
- Hospital del Mar
Cholecystitis, Cholecystitis, Acute
EOIB for Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy, while less painful compared to conventional methods, is still a surgery that can cause significant pain for patients.
- Conditions
- Cholecystitis, Cholecystitis, Acute, Cholecystitis, Chronic, Cholecystitis; Gallstone
- Trial name
- NCT06656299
- Testing
- ultrasound guided external oblique intercostal plane block, Bupivacaine injection, paracetamol, tramadol, and ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Acute Cholecystitis
Diagnostic Value of Deep Learning-Based Rapid MRI in Preoperative Evaluation of Acute Cholecystitis
This is a single-center, prospective observational study at Peking Union Medical College Hospital. The main goal is to evaluate the image quality and clinical value of a new fast abdominopelvic MRI sequence that uses deep…
- Trial name
- NCT07551375
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Cholecystitis, Cholecystectomy
Fast Track Pathway to Accelerated Cholecystectomy
More than 10% of Canadians have gallstones, and approximately 10% of these individuals will develop gallbladder inflammation related to gallstones, which is referred to as acute cholecystitis (AC).
- Trial name
- FAST (NCT04033822)
- Testing
- cholecystectomy
- Where
- 4 sites in Canada
- Volunteers
- 60 people
- Sponsor
- P.J. Devereaux