Clinical trials: Acute Cardiac Failure
Acute Decompensated Heart Failure (ADHF)
The Effect of Dapagliflozin on Patients With Cardiomyopathy
This randomized controlled trial evaluates the efficacy and tolerability of early initiation of dapagliflozin in adult patients hospitalized with acute heart failure (AHF).
- Trial name
- Dapagliflozin (NCT07076615)
- Testing
- Dapagliflozin (DAPA), Diuretic
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- May Mohamed Abdalla
Critically Ill, Acute Respiratory Failure
The EXCEL Registry of Patients Requiring ECMO
ECMO is associated with significant costs, risks and requires specialist training and expertise. EXCEL is a novel, high-quality, detailed prospective registry of patients requiring ECMO in Australia and New Zealand.
- Conditions
- Critically Ill, Acute Respiratory Failure, Acute Heart Failure, Cardiac Arrest
- Trial name
- NCT03793257
- Where
- 29 sites in Australia, New Zealand
- Volunteers
- 3,000 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Acute Coronary Syndrome, Renal Failure
Adaptation Dose of Enoxaparin in Moderate Renal Failure Patients With Acute Coronary Syndrome
The objective of the VALIDE study is to validate that a 25% dose reduction of enoxaparine in patients with moderate renal failure (creatinine clearance between 30 and 50 ml/min) and hospitalized for an acute coronary syndrome…
- Trial name
- NCT00412802
- Testing
- dose adaptation of Enoxaparin, normal injection of Enoxaparine
- Where
- 9 sites in France
- Volunteers
- 67 people
- Sponsor
- French Cardiology Society
Acute Heart Failure, Acute Myocardial Infarction
N-3 Fatty Acids for the Prevention of Atrial Fibrillation in Patients With Acute Heart Failure
Our study is to investigate the effect of N-3 Fatty Acids for the prevention of atrial fibrillation in patients with acute heart failure or acute myocardial infarction
- Trial name
- NCT00692718
- Testing
- Epadel, Eicosapentaenoic acid
- Volunteers
- 160 people
- Sponsor
- Osaka General Medical Center
Acute Myocardial Infarction, Cardiogenic Shock
Assessment of ECMO in Acute Myocardial Infarction Cardiogenic Shock
Data from case series and large retrospective trials suggest that the early treatment of cardiogenic shock AMI patients with the association of VA-ECMO and IABP may significantly decrease mortality, which is still unacceptably…
- Trial name
- ANCHOR (NCT04184635)
- Testing
- VA-ECMO
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Heart Failure (AHF)
Evaluating the Effects of Nitroglycerin on Heart Function and Urinary Output in Patients With Acute Heart Failure
This study aims to understand how nitroglycerin affects patients with acute heart failure, a condition where the heart struggles to pump blood effectively, leading to fluid buildup and breathing difficulties.
- Trial name
- NCT06682260
- Testing
- Nitroglycerin (NTG)
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Heart Failure NYHA Class I, Heart Failure NYHA Class II
Future Patient - Telerehabilitation of Heart Failure Patients
The idea behind the Future Patient research project is to develop a telerehabilitation program and tools for patients with heart failure.
- Conditions
- Heart Failure NYHA Class I, Heart Failure NYHA Class II, Heart Failure NYHA Class III, Heart Failure NYHA Class IV
- Trial name
- NCT03388918
- Testing
- Telerehabilitation
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Aalborg University
Acute Heart Failure
Gulf Acute Heart Failure Registry
The Gulf Heart Association (GHA) sponsored Gulf acute heart failure registry (Gulf CARE)is a multinational , multicentre, prospective, observational, hospital-based registry of patients with acute heart failure(AHF) with 3 month…
- Trial name
- GulfCARE (NCT01467973)
- Where
- Oman
- Volunteers
- 5,005 people
- Sponsor
- Gulf Heart Association
Hyponatremia
THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation
The purpose of this study is to determine the safety and efficacy of lixivaptan in the treatment of hyponatremia in patients with congestive heart failure.
- Trial name
- NCT00578695
- Testing
- lixivaptan
- Where
- 287 sites in United States, Argentina and 13 more
- Volunteers
- 652 people
- Sponsor
- CardioKine Inc.
Acute Myocardial Infarction
Impact of EMpagliflozin on Cardiac Function and Biomarkers of Heart Failure in Patients With Acute MYocardial Infarction
This study is planned to investigate the impact of Empagliflozin on biomarkers of heart failure in patients with myocardial infarction with and without type 2 diabetes mellitus within 6 months after the event.
- Trial name
- EMMY (NCT03087773)
- Testing
- Empagliflozin 10 mg
- Where
- 11 sites in Austria
- Volunteers
- 476 people
- Sponsor
- Medical University of Graz
Heart Failure
Short Term Hemodynamic Effects of Controlled Slow Breathing With Biofeedback in Patients With Heart Failure
Heart failure is associated with faster breathing, which has a negative impact on the functioning of the heart. This leads to fatigue, shortness of breath, and exercise intolerance.
- Trial name
- NCT00971386
- Testing
- Slow breathing
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Heart Failure, Acute Heart Failure
Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap?
The goal of this clinical trial is to learn whether a rapid and intensive optimization of heart failure medications in women can improve outcomes after hospitalization for heart failure.
- Conditions
- Heart Failure, Acute Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Preserved Ejection Fraction (HFPEF)
- Trial name
- PopS-HF (NCT07295522)
- Testing
- Guideline-Directed Medical Therapy (GDMT)
- Where
- 12 sites in Italy
- Volunteers
- 368 people
- Sponsor
- IRCCS Policlinico S. Donato
Infection, Hypervolemia
Observational Study to Evaluate Peripheral IntraVenous Analysis (PIVA) in Euvolemic, Hypovolemic, and Hypervolemic Emergency Department Patients
The overall goal of this multicenter project is to characterize the expected normal range of Peripheral IntraVenous Volume Analysis (PIVA) values during a euvolemic state, and how those ranges may be altered by comorbidities; the…
- Conditions
- Infection, Hypervolemia, Hypovolemia, Septic Shock
- Trial name
- PIVA (NCT03736421)
- Testing
- Peripheral Intravenous Analysis (PIVA), Non-invasive fluid response measure, Passive leg raise (PLR)
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Dyspnea; Cardiac
Bedside Lung Ultrasonography by Nurses in Acute Dyspnea.
This study assesses the potential of lung ultrasonography to diagnose heart failure.
- Trial name
- LUS (NCT05126940)
- Testing
- we perform a lung ultrasound to all the patients admitted for dyspnea independantly from the final diagnosis
- Where
- Tunisia
- Volunteers
- 216 people
- Sponsor
- University of Monastir
Heart Failure, Metabolic Alkalosis
Metabolic Alkalosis in Heart Failure
Metabolic alkalosis (MA) is the most common acid-base disorder and when it's severe it can have effects on cellular function and contribute to an increase in mortality.
- Conditions
- Heart Failure, Metabolic Alkalosis, Diuretics Drug Reactions, Decompensated Heart Failure
- Trial name
- NCT04740242
- Where
- Spain
- Volunteers
- 672 people
- Sponsor
- Spanish Society of Internal Medicine
Early Management, Acute Heart Failure
Early Management Strategies of Acute Heart Failure for Patients With NSTEMI
There are always poor outcomes in patients with acute myocardial infarction(AMI) combined with elevated BNP/NT-proBNP level. An elevated BNP/NT-proBNP level highly indicates acute heart failure(AHF).Levosimendan is recommended in…
- Conditions
- Early Management, Acute Heart Failure, NSTEMI - Non-ST Segment Elevation MI
- Trial name
- EMSAHF (NCT03189901)
- Testing
- Regular management+Levosimendan
- Where
- 14 sites in China
- Volunteers
- 470 people
- Sponsor
- Qilu Hospital of Shandong University
Acute Kidney Injury, Heart Failure
Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major…
- Conditions
- Acute Kidney Injury, Heart Failure, Contrast Induced Nephropathy, Coronary Angiography
- Trial name
- RICH (NCT04982419)
- Testing
- Remote ischemic preconditioning
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Acute Respiratory Distress Syndrome, Right Ventricular Dysfunction
Detection of Right Ventricular Dysfunction by 2D Strain During Acute Respiratory Distress Syndrom (ARDS)
Acute respiratory distress syndrome (ARDS) and mechanical ventilation can lead to right ventricular dysfunction and ultimately right ventricular failure by increasing pulmonary vascular resistances and pressure load.
- Conditions
- Acute Respiratory Distress Syndrome, Right Ventricular Dysfunction, Right Heart Failure, Acute Cor Pulmonale
- Trial name
- STRAIN (NCT01757522)
- Where
- France
- Volunteers
- 47 people
- Sponsor
- University Hospital, Grenoble
Heart Failure
Trial Assessing the Effectiveness of Ivabradine Started at Discharge From the Observation Unit
Ivabradine (IVA) has been shown to decrease the risk of hospitalizations for worsening Heart Failure and was associated with a trend towards improved mortality in the SHIFT1 trial.
- Trial name
- OBSERVE-IVA (NCT03168529)
- Testing
- Ivabradine
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Phillip Levy
Acute Heart Failure Syndrome
Respiratory Virus Infections in Acute Heart Failure
Patients admitted to the cardiology department with acute heart failure who have a nasopharyngeal respiratory virus PCR test performed within 72 hours of admission will be enrolled in the study cohort.
- Trial name
- NCT06967441
- Where
- 3 sites in South Korea
- Volunteers
- 360 people
- Sponsor
- Minjae Yoon
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.