Clinical trials: Acute Cardiac Failure
Acute Heart Failure
A Study to Evaluate the Efficacy and Safety of Shenfu Zhusheye in Patients With Acute Heart Failure
The purpose of this study is to evaluate the efficacy and safety of Shenfu Zhusheye in patients with acute heart failure.
- Trial name
- NCT02135835
- Testing
- Shenfu Zhusheye, 5% glucose injection
- Where
- 25 sites in China
- Volunteers
- 365 people
- Sponsor
- China Resources Sanjiu Medical & Pharmaceutical Co., Ltd.
Acute Coronary Syndrome, Heart Failure
incidenCe and predictOrs of heaRt fAiLure After Acute coronarY Syndrome: CORALYS
Single-cohort retrospective study evaluating the incidence and prognostic markers of heart failure following acute coronary syndrome treated by percutaneous coronary intervention
- Trial name
- CORALYS (NCT04895176)
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Acute Heart Failure (AHF), Congestion, Venous
Simple Urine Composition-based Personalized Algorithm for Effective Congestion Relief in Decompensated Heart Failure
The aim of this study is to evaluate the effectiveness of loop diuretic adaptative algorithm that is based on machine learning, urine output prediction tool, in decongestion of acute heart failure patients.
- Trial name
- SAFER-DHF (NCT07099885)
- Testing
- Standard of Care (SOC), Algorithhm-based decongestion
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Wroclaw Medical University
Acute Decompensated Heart Failure, Congestive Heart Failure Compensated
Role of USCOM in Adult Patients With Heart Failure
Objective: The Ultrasonic Cardiac Output Monitor (USCOM) is a non-invasive, quantitative method for measuring and monitoring cardiovascular haemodynamic parameters in patients. The aims of this study are: 1.
- Trial name
- NCT02289508
- Testing
- Ultrasonic cardiac output monitor, Echocardiography
- Where
- China
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Kidney Tubular Necrosis, Acute
Allogeneic Multipotent Stromal Cell Treatment for Acute Kidney Injury Following Cardiac Surgery
The purpose of this trial is to determine if the administration of allogeneic MSCs at defined doses is safe in patients who are at high risk of developing significant Acute Kidney Injury (AKI) after undergoing on-pump cardiac…
- Trial name
- NCT00733876
- Testing
- Multipotent Stromal Cells, Administration of MSC
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- AlloCure Inc.
Acute Decompensated Heart Failure
Effect of Providing Education and Patient's Inferior Vena Cava Ultrasound Images on Adherence to a Heart Failure Regimen
Heart failure is a common, costly, and disabling condition characterized by recurrent exacerbations. Episodes of acute decompensated heart failure (ADHF) account for the largest proportion of admissions and 30-day readmissions to…
- Trial name
- NCT03488979
- Testing
- educational interventional group
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Heart Failure
Self-management Adherence in Heart Failure Patients
Non-adherence to self-management behaviors is prevalent and accounts for hospital readmissions in heart failure (HF) patients 65 years of age and older.
- Trial name
- PATCH (NCT01964053)
- Testing
- PATCH intervention, Usual care
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- University of Nebraska
Acute Decompensated Heart Failure
Cardiorenal Interactions During Treatment of Acute Decompensated Heart Failure: Diuretics Versus Ultrafiltration
The CRUF trial is a prospective randomized monocentric trial comparing different impact of diuretics versus ultrafiltration on renal congestion, plasma refill rate, echocardiographic filling pressures, neurohormonal activation…
- Trial name
- CRUF (NCT01138683)
- Testing
- ultrafiltration, diuretics
- Where
- Belgium
- Volunteers
- 1 people
- Sponsor
- University Hospital, Ghent
ADHF
3-dimensional Sensor Technology to Quantify Leg-edema
The purpose of the study is two-fold: 1. to test 3-dimensional reconstruction of leg-edema in patients hospitalized for acute heart failure with leg-edema. 2.
- Trial name
- NCT01700023
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- Medical University of Graz
Heart Failure, Systolic, Heart Failure; With Decompensation
Fluid Restriction in Patients With Heart Failure
There is a concept increasingly consolidated by clinical evidence that at each hospitalization due to HF decompensation there is a substantial loss of quality of life, which is associated with an initial period of great clinical…
- Conditions
- Heart Failure, Systolic, Heart Failure; With Decompensation, Pulmonary Congestion
- Trial name
- NCT04611594
- Testing
- Fluid restriction
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Acute Respiratory Distress Syndrome, Right Ventricular Dysfunction
Detection of Right Ventricular Dysfunction by 2D Strain During Acute Respiratory Distress Syndrom (ARDS)
Acute respiratory distress syndrome (ARDS) and mechanical ventilation can lead to right ventricular dysfunction and ultimately right ventricular failure by increasing pulmonary vascular resistances and pressure load.
- Conditions
- Acute Respiratory Distress Syndrome, Right Ventricular Dysfunction, Right Heart Failure, Acute Cor Pulmonale
- Trial name
- STRAIN (NCT01757522)
- Where
- France
- Volunteers
- 47 people
- Sponsor
- University Hospital, Grenoble
Cardiac Surgery, Extracorporeal Circulation
RRI Compared With NephroCheckTM to Predict Acute Renal Failure After Cardiac Surgery.
Postoperative acute renal failure is a frequent complication after cardiac surgery. The current practice cannot predict Acute Kidney Injuries (AKI) early enough to reduce a significant kidney assault and prevent an organic…
- Conditions
- Cardiac Surgery, Extracorporeal Circulation, Nephrocheck, Renal Failure
- Trial name
- NCT02325726
- Testing
- Renal Resistive Index compared with NephroCheckTM
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Bordeaux
Heart Failure
Access Natriuretic Peptide Assay(s) Pivotal - Emergency Department Subject Enrollment and Specimen Collection
The purpose of the pivotal study is to collect blood specimens and clinical data from patients suspected of having Heart Failure (HF), which will be tested at a future date on Natriuretic Peptide assay(s) to validate diagnostic…
- Trial name
- NCT04169815
- Testing
- Access Immunodiagnostic Products
- Where
- 15 sites in United States
- Volunteers
- 2,370 people
- Sponsor
- Beckman Coulter, Inc.
Acute Kidney Injury
Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery
This project aims to conduct an international, prospective, multicentre, observational study to determine the incidence of Postoperative Acute Kidney Injury (PO-AKI) in hospitalized children after noncardiac surgery.
- Trial name
- POAKIDS (NCT07351149)
- Where
- 16 sites in Australia, Brazil and 8 more
- Volunteers
- 2,000 people
- Sponsor
- Uppsala University
Heart Failure
Ultra-sound Assisted Management of Heart Failure
The purpose of this study is to evaluate the impact of using hand carried ultrasound measurements of volume status in directing treatment of heart failure patients admitted with acute exacerbation.
- Trial name
- USA-HF (NCT04376424)
- Testing
- Hand Held Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Heart Failure, COPD
Ultrasound in Acute Dyspnea in the Field
Acute heart failure is one of the main causes of acute respiratory distres in prehospital emergency setting. The early and correct diagnosis is important because the misdiagnosis can result in deleterious consequeance to…
- Conditions
- Heart Failure, COPD, Asthma
- Trial name
- NCT01235182
- Where
- Slovenia
- Volunteers
- 248 people
- Sponsor
- University Medical Centre Maribor
Cardiac Output, High, Heart Failure
The Effect of Semi Fowler 30' Right Lateral on Cardiac Output in Acute Heart Failure
Heart failure is a special clinical syndrome such as difficulty breathing, fatigue, and swollen legs characterized by increased JVP, crackle lung sounds, and peripheral edema caused by heart disorders both structural and/or…
- Conditions
- Cardiac Output, High, Heart Failure, Pulmonary Edema With Heart Failure, Dyspnea; Cardiac
- Trial name
- SETTLECO (NCT06039397)
- Testing
- Semifowler 30' Right Lateral Body Position
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Universitas Indonesia
Acute Coronary Syndrome, Chronic Kidney Disease
Platelet Resistance With Ticagrelor or Standard-Dose Clopidogrel Among CKD and ACS Patients
A 4 week-duration cross-over study on Ticagrelor and Clopidogrel for the Acute Coronary Syndrome (ACS) and Chronic Kidney Disease (CKD) subjects, focusing on the platelet inhibition and safety observation.
- Conditions
- Acute Coronary Syndrome, Chronic Kidney Disease, End-Stage Renal Disease
- Trial name
- APROVE-CKD (NCT02459288)
- Testing
- Clopidogrel first, Ticagrelor first
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Ping-Yen Liu
Myocardial Infarction (MI), Pacemaker Implantation
Augmented Reality as Discharge Information for Hospitalized Cardiology Patients
The goal of this clinical trial is to find out whether a simple augmented reality tool provided at hospital discharge can improve patients' understanding of their care, adherence to treatment, and health outcomes, compared with…
- Conditions
- Myocardial Infarction (MI), Pacemaker Implantation, Heart Failure, Atrial Fibrillation (AF)
- Trial name
- RACAR (NCT07399379)
- Testing
- Augmented reality app
- Where
- Spain
- Volunteers
- 303 people
- Sponsor
- Hospital Universitario Getafe
Heart Failure, Acute Myocardial Infarction (AMI)
Efficacy and Safety of Early Initiation of Vericiguat in Heart Failure After Acute Myocardial Infarction
Heart failure (HF) is a severe cardiovascular disease with extremely high morbidity and mortality rates worldwide, and ischemic cardiomyopathy is an important cause of heart failure.
- Conditions
- Heart Failure, Acute Myocardial Infarction (AMI), Acute Heart Failure (AHF)
- Trial name
- VIC-MI (NCT06812546)
- Testing
- Vericiguat
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Dongying Zhang
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